QTTB Insider Trading - Q32 Bio Inc.

Shares Outstanding	12,197,615 shares
Insider Shares	27,366,359 shares
Total Insiders	63

Insider Sentiment Score

The Insider Sentiment Score finds the companies being bought by corporate insiders.

It is the result of a sophisticated, multi-factor quantitative model that identifies companies with the highest levels of insider accumulation. The scoring model uses a combination of the net number of insiders buying the prior 90 days, the total shares bought as a percentage of float, and the total shares owned by insiders. The number ranges from 0 to 100, with higher numbers indicating a higher level of accumulation to its peers, and 50 being the average.

Update Frequency: Daily

See Insiders Top Picks, which provides a list of companies with highest insider accumulation.

See Highest Ranking Stocks

Officer Sentiment Score

The Officer Sentiment Score finds companies being bought by Corporate Officers.

By definition Corporate Officers are Corporate Insiders, but unlike some of the other Insiders (10% Shareholders and Board Members), Officers work for the company on a daily basis, and they user their own money when trading. (10% Shareholders and Board Members are often fund managers managing other people’s money.) As such, insider trades made by Officers are much more significant and should be treated appropriately.

Like the Insider Sentiment Score, the Officer Sentiment Score is the result of a sophisticated, multi-factor quantitative model that identifies companies with the highest levels of officer accumulation.

Update Frequency: Daily

See Insiders Top Picks, which provides a list of companies with highest insider sentiment.

See Highest Ranking Stocks

Key Insider Metrics

This card shows how the company ranks along various insider metrics. The percentile rank shows how this company compares to other companies in the US markets. Higher rankings are indicative of better situations.

For example, it is generally accepted that insider buying is a positive indicator, so companies with more insider buying would rank higher than companies with less insider buying (or even insider selling).

Net Number of Insiders Buying (Rank)

-3 ( )

10604 out of 11314

Net Number of Insiders Buying is the total number of insiders buying minus the total number of insiders selling in the last 90 days. The percentile rank is shown here (range from 0 to 100%).

Percent of Float Bought by Insiders (Rank)

-0.329 %( )

10871 out of 11237

Percent of Float Bought by Insiders is the total number of shares purchased by insiders minus the total number of shares sold by insiders in the last 90 days, divided by the total float and multiplied by 100.

Insider Trading Chart

Q32 Bio Inc. insider trades are shown in the following chart. Insiders are officers, directors, or significant investors in a company. In general, it is generally illegal for insiders to make trades in their companies based on material, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4.

Insider Roster and Profitability Metrics

This table shows the list known insiders, and is generated automatically from filings disclosed to the SEC. In addition to the names, most recent title, and director, officer, or 10% owner designation, we provide the latest disclosed holdings. Additionally, when possible we provide the historical trade performance for the insider. The historical trade performance is a weighted average of the performance of actual open-market purchase transactions made by the insider. For more information on how this is calculated, watch this YouTube webinar.

See our leaderboard of most profitable insider traders.

Insider	Shares Owned	Split Adjusted
5AM Co-Investors IV, L.P. 10% Owner - [10%]	181,435	181,435
5AM Partners IV, LLC 10% Owner - [10%]	181,435	181,435
5AM Ventures IV, L.P. 10% Owner - [10%]	181,435	181,435
ARCH Venture Fund VIII Overage, L.P. 10% Owner - [10%]	5,768,694	5,768,694
ARCH Venture Fund VIII, L.P. 10% Owner - [10%]	5,768,694	5,768,694
ARCH Venture Partners VIII, L.P. 10% Owner - [10%]	5,768,694	5,768,694
ARCH Venture Partners VIII, LLC 10% Owner - [10%]	5,768,694	5,768,694
Paul Alloway See Remarks - [O]	2,596	2,596
Atlas Venture Fund X, L.P. 10% Owner - [10%]	724,549	724,549
Clinton Bybee 10% Owner - [10%]	5,768,694	5,768,694
Michael Lee Blum Chief Commercial Officer - [O]	3,280	3,280
Keith Crandell 10% Owner - [10%]	5,768,694	5,768,694
Jason Campagna Chief Medical Officer - [O]	37,500	37,500
Saswati Chatterjee 10% Owner - [10%]	950,028	950,028
Gabriel Cohn Chief Medical Officer - [O]	2,629	2,629
Management Co Deerfield 10% Owner - [10%]	0	0
Deerfield Partners, L.p. Director, 10% Owner - [D] [10%]	0	0
John D Diekman 10% Owner - [10%]	181,435	181,435
Deerfield Healthcare Innovations Fund, L.P. 10% Owner - [10%]	0	0
Deerfield Mgmt HIF, L.P. 10% Owner - [10%]	0	0
Deerfield Mgmt III, L.P. 10% Owner - [10%]	0	0

Insider	Shares Owned	Split Adjusted
Deerfield Mgmt L.P. Director, 10% Owner - [D] [10%]	0	0
Deerfield Private Design Fund III, L.P. 10% Owner - [10%]	0	0
James E Flynn 10% Owner - [10%]	0	0
Management Pte Ltd Fullerton 10% Owner - [10%]	3,220,293	3,220,293
Steven Gillis Director - [D]	6,068,695	6,068,695
Grayzel David S. Director - [D]	724,549	724,549
Gregory Richard J. Director - [D]	10,806	10,806
Julie Jordan Chief Medical Officer - [O]	7,496	7,496
Lee Kalowski CFO and President - [O]	49,010	49,010
Timothy P Kelly Chief Operating Officer - [O]	2,224	2,224
Kathleen Laporte Director - [D]	5,431	5,431
Sven Ante Lundberg Director - [D]	1,200	1,200
Charles Jr Michaud See Remarks - [O]	927	927
Jodie Pope Morrison CEO, Director - [D] [O]	121,506	121,506
Robert Nelsen 10% Owner - [10%]	5,768,694	5,768,694
Ag Novartis 10% Owner - [10%]	1,979,226	1,979,226
Novartis Institutes for BioMedical Research, Inc. 10% Owner - [10%]	1,979,226	1,979,226
Orbimed Advisors Llc Director, 10% Owner - [D] [10%]	2,252,987	2,252,987
Kush Parmar Director - [D]	181,435	181,435
Matthew R Patterson	18,000
Poulton Jeffrey V.	36,000

Insider	Shares Owned	Split Adjusted
Alise Reicin	18,000
Scott M Rocklage 10% Owner - [10%]	181,435	181,435
Siyamak Rasty Chief Operating Officer - [O]	222,707	222,707
Rock Springs Capital LLC 10% Owner - [10%]	645,845	645,845
Rock Springs Capital Management LP 10% Owner - [10%]	645,845	645,845
Rock Springs Capital Master Fund LP 10% Owner - [10%]	645,845	645,845
Mahendra Shah Director - [D]	909,742	909,742
Schwab Andrew J. 10% Owner - [10%]	181,435	181,435
Albert Seymour See Remarks, Director - [D] [O]	150,874	150,874
W Bradford Smith See Remarks - [O]	14,219	14,219
TLS Beta Pte. Ltd. 10% Owner - [10%]	3,220,293	3,220,293
Arthur Tzianabos Director - [D]	7,983	7,983
Temasek Holdings (Private) Ltd 10% Owner - [10%]	3,220,293	3,220,293
Temasek Life Sciences Private Ltd 10% Owner - [10%]	3,220,293	3,220,293
Mary Thistle	18,000
V-Sciences Investments Pte Ltd 10% Owner - [10%]	3,220,293	3,220,293
VV Manager LLC 10% Owner - [10%]	770,845	770,845
Vida Ventures, LLC 10% Owner - [10%]	770,845	770,845
Violette Shelia M. Chief Scientific Officer - [O]	94,661	94,661
Cameron Wheeler	15,580
Diyong Xu Director, 10% Owner - [D] [10%]	2,252,987	2,252,987

Report errors via our new Insider Auditing Tool

Track Records of Insider Purchases - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in QTTB / Q32 Bio Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical .

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date	Insider	Reported Shares	Reported Price	Adjusted Shares	Adjusted Price	Cost Basis	Days to Max	Price at Max	Max Profit ($)	Max Return (%)
2019-04-12	Flynn James E	533,333	22.5000	533,333	22.5000	11,999,992	11	23.26	405,334	3.38
2018-04-02	Temasek Holdings (Private) Ltd	625,000	16.0000	625,000	16.0000	10,000,000
2018-04-02	Vida Ventures, LLC	375,000	16.0000	375,000	16.0000	6,000,000
2018-04-02	Rock Springs Capital Management LP	250,000	16.0000	250,000	16.0000	4,000,000
2018-04-02	Flynn James E	625,000	16.0000	625,000	16.0000	10,000,000
2018-04-02	Flynn James E	625,000	16.0000	625,000	16.0000	10,000,000

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

Track Records of Insider Sales - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in QTTB / Q32 Bio Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical .

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date	Insider	Reported Shares	Reported Price	Adjusted Shares	Adjusted Price	Cost Basis	Days to Min	Price at Min	Max Loss Avoided ($)	Max Loss Avoided (%)
2025-08-26	Kalowski Lee	4,240	1.8010	4,240	1.8010	7,636	9	1.6600	-598	-7.83
2025-08-26	Violette Shelia M.	2,990	1.8010	2,990	1.8010	5,385
2025-08-26	Morrison Jodie Pope	10,494	1.8010	10,494	1.8010	18,900
2024-03-25	TZIANABOS ARTHUR	265	24.2000	265	24.2000	6,413
2023-08-03	Jordan Julie	1,308	1.3900	1,308	1.3900	1,818
2020-12-22	5AM Ventures IV, L.P.	20,000	12.8200	20,000	12.8200	256,400
2020-12-22	5AM Ventures IV, L.P.	480,000	12.8200	480,000	12.8200	6,153,600
2020-12-14	5AM Ventures IV, L.P.	13,703	11.8800	13,703	11.8800	162,792
2020-12-14	5AM Ventures IV, L.P.	6,297	13.0609	6,297	13.0609	82,244

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

Transaction History

Click the link icon to see the full transaction history. Transactions reported as part of a 10b5-1 automatic trading plan will have an X in the column marked 10b-5.

File Date	Trade Date	Form	Insider	Ticker	Security Title	Code	Direct	Exercise Price	Unit Price	Units Changed	Value Changed (1K)	Remaining Options	Remaining Shares
2025-08-28	2025-08-26	4	Morrison Jodie Pope	QTTB	Common Stock	S - Sale	D		1.8010	-10,494	-19		121,506
2025-08-28	2025-08-26	4	Violette Shelia M.	QTTB	Common Stock	S - Sale	D		1.8010	-2,990	-5		58,384
2025-08-28	2025-08-26	4	Kalowski Lee	QTTB	Common Stock	S - Sale	D		1.8010	-4,240	-8		49,010
2025-02-27	2025-02-24	4	Kalowski Lee	QTTB	Common Stock	A - Award	D			53,250			53,250
2025-02-26	2025-02-24	4	Morrison Jodie Pope	QTTB	Common Stock	A - Award	D			132,000			132,000
2025-02-26	2025-02-24	4	Campagna Jason	QTTB	Common Stock	A - Award	D			37,500			37,500
2025-02-26	2025-02-24	4	Violette Shelia M.	QTTB	Common Stock	A - Award	D			37,500			61,374
2024-10-16	2024-10-15	4	Violette Shelia M.	QTTB	Common Stock	M - Exercise	D		7.2900	6,000	44		23,874
2024-10-16	2024-10-11	4	Violette Shelia M.	QTTB	Common Stock	M - Exercise	D		3.1200	4,574	14		17,874
2024-10-10	2024-10-08	4	Violette Shelia M.	QTTB	Common Stock	M - Exercise	D		3.1200	13,300	41		13,300
2024-08-14	2024-03-25	4	TZIANABOS ARTHUR	QTTB	Common Stock	S - Sale	D		24.2000	-265	-6		7,983
2024-08-14	2024-03-25	4	TZIANABOS ARTHUR	QTTB	Common Stock	M - Exercise	D			1,095			8,248
2024-04-23	2024-03-25	4	Alloway Paul	QTTB	Common Stock	S - Sale	D		24.2100	-268	-6		2,596
2024-04-23	2024-03-25	4	Michaud Charles Jr	QTTB	Common Stock	S - Sale	D		24.2000	-75	-2		927
2024-03-27		3	Violette Shelia M. By Violette Holdings LLC	QTTB	Common Stock		I						36,277
2024-03-27		3	GRAYZEL DAVID S. By Atlas Venture Opportunity Fund II, L.P.	QTTB	Common Stock		I						724,549
2024-03-27		3	GRAYZEL DAVID S. By Atlas Venture Fund X, L.P.	QTTB	Common Stock		I						864,261
2024-03-27		3	GRAYZEL DAVID S. By Atlas Venture Opportunity Fund I, L.P.	QTTB	Common Stock		I						503,296
2024-03-27		3	Xu Diyong By OrbiMed Private Investments VII, LP	QTTB	Common Stock		I						2,252,987
2024-03-27		3	LAPORTE KATHLEEN By the Kathleen LaPorte Revocable Trust	QTTB	Common Stock		I						5,431
2024-03-27		3	ORBIMED ADVISORS LLC By OrbiMed Private Investments VII, LP	QTTB	Common Stock		I						2,252,987
2024-03-27		3	Atlas Venture Fund X, L.P. By Atlas Venture Opportunity Fund I, L.P.	QTTB	Common Stock		I						503,296
2024-03-27		3	Atlas Venture Fund X, L.P.	QTTB	Common Stock		D						864,261
2024-03-27		3	Atlas Venture Fund X, L.P. By Atlas Venture Opportunity Fund II, L.P.	QTTB	Common Stock		I						724,549
2024-03-27		3	Lundberg Sven Ante	QTTB	Common Stock		D						1,200
2024-03-27	2024-03-25	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			23,530			51,566
2024-03-27	2024-03-25	4	Michaud Charles Jr	FIXX	Common Stock	M - Exercise	D			6,448			18,046
2024-02-15	2024-01-09	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		0.5711	-13,037	-7		128,778
2024-02-15	2024-01-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	M - Exercise	D			19,140			141,815
2024-02-15	2024-01-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	M - Exercise	D			14,280			122,675
2024-01-05	2024-01-03	4	Alloway Paul	FIXX	Common Stock	S - Sale	D		0.5660	-7,280	-4		28,036
2024-01-05	2024-01-03	4	Michaud Charles Jr	FIXX	Common Stock	S - Sale	D		0.5710	-1,708	-1		11,598
2024-01-03	2024-01-01	4	Michaud Charles Jr	FIXX	Common Stock	M - Exercise	D			2,640			13,306
2024-01-03	2024-01-01	4	Michaud Charles Jr	FIXX	Common Stock	M - Exercise	D			1,056			10,666
2024-01-03	2024-01-01	4	Michaud Charles Jr	FIXX	Common Stock	M - Exercise	D			544			9,610
2024-01-03	2024-01-01	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			8,910			35,316
2024-01-03	2024-01-01	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			5,280			26,406
2024-01-03	2024-01-01	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			4,420			21,126
2023-12-11		3/A	Michaud Charles Jr	FIXX	Common Stock		D						9,066
2023-11-17		3	Michaud Charles Jr	FIXX	Common Stock		D						2,112
2023-09-08	2023-09-06	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		1.1502	-1,448	-2		150,874
2023-09-08	2023-09-06	4	Seymour Albert	FIXX	Common Stock	M - Exercise	D			4,620			152,322
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	S - Sale	D		1.3900	-1,308	-2		7,496
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	M - Exercise	D			4,644			8,804
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	S - Sale	D		1.3900	-109	-0		4,160
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	M - Exercise	D			387			4,269
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	S - Sale	D		1.3900	-436	-1		3,882
2023-08-07	2023-08-03	4	Jordan Julie	FIXX	Common Stock	M - Exercise	D			1,548			4,318
2023-08-04	2023-08-02	4	Jordan Julie	FIXX	Common Stock	S - Sale	D		1.3100	-99	-0		2,770
2023-08-04	2023-08-02	4	Jordan Julie	FIXX	Common Stock	M - Exercise	D			350			2,869
2023-03-16		3	Jordan Julie	FIXX	Common Stock		D						2,519
2023-03-06	2023-03-02	4	Alloway Paul	FIXX	Common Stock	S - Sale	D		1.4467	-10,965	-16		16,706
2023-01-20		3/A	Blum Michael Lee	FIXX	Common Stock		D						3,280
2023-01-11	2023-01-09	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		1.3904	-3,620	-5		143,166
2023-01-11	2023-01-09	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		1.3912	-3,729	-5		14,219
2023-01-11	2023-01-09	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		1.3905	-10,616	-15		108,395
2023-01-11	2023-01-09	4	Alloway Paul	FIXX	Common Stock	S - Sale	D		1.3903	-3,090	-4		20,103
2023-01-11	2023-01-09	4	Blum Michael Lee	FIXX	Common Stock	S - Sale	D		1.3904	-2,454	-3		13,538
2023-01-04	2023-01-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D			6,930			17,948
2023-01-04	2023-01-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D			6,600			11,018
2023-01-04	2023-01-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	M - Exercise	D			19,140			119,011
2023-01-04	2023-01-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	M - Exercise	D			13,860			99,871
2023-01-04	2023-01-01	4	Seymour Albert	FIXX	Common Stock	M - Exercise	D			6,930			146,786
2023-01-04	2023-01-01	4	Seymour Albert	FIXX	Common Stock	M - Exercise	D			4,290			139,856
2023-01-04	2023-01-01	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			5,280			23,193
2023-01-04	2023-01-01	4	Alloway Paul	FIXX	Common Stock	M - Exercise	D			4,290			17,913
2023-01-04	2023-01-01	4	Blum Michael Lee	FIXX	Common Stock	M - Exercise	D			4,950			15,992
2023-01-04	2023-01-01	4	Blum Michael Lee	FIXX	Common Stock	M - Exercise	D			2,640			11,042
2022-04-21	2022-04-21	4	Seymour Albert	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	1.78		60,000		60,000
2022-03-11		3	Blum Michael Lee	FIXX	Common Stock		D						6,780
2022-03-11		3	Alloway Paul	FIXX	Common Stock		D						10,226
2022-02-28	2022-02-24	4	Seymour Albert	FIXX	Restricted Stock Units	A - Award	D			21,000		21,000
2022-02-28	2022-02-24	4	Seymour Albert	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	2.71		128,000		128,000
2022-02-28	2022-02-24	4	Smith W Bradford	FIXX	Restricted Stock Units	A - Award	D			21,000		21,000
2022-02-28	2022-02-24	4	Smith W Bradford	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	2.71		126,000		126,000
2022-02-28	2022-02-24	4	TZIANABOS ARTHUR	FIXX	Restricted Stock Units	A - Award	D			58,000		58,000
2022-02-28	2022-02-24	4	TZIANABOS ARTHUR	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	2.71		350,000		350,000
2022-02-28	2022-02-24	4	Kelly Timothy P	FIXX	Restricted Stock Units	A - Award	D			4,800		4,800
2022-02-28	2022-02-24	4	Kelly Timothy P	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	2.71		28,200		28,200
2022-01-12	2022-01-05	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		3.7802	-2,182	-8		4,418
2022-01-12	2022-01-01	4	Smith W Bradford	FIXX	Restricted Stock Units	M - Exercise	D			-6,600		13,400
2022-01-12	2022-01-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D			6,600			6,600
2022-01-12	2022-01-05	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		3.7801	-1,661	-6		131,646
2022-01-12	2022-01-01	4	Seymour Albert	FIXX	Restricted Stock Units	M - Exercise	D			-4,290		8,710
2022-01-12	2022-01-01	4	Seymour Albert	FIXX	Common Stock	M - Exercise	D			4,290			133,307
2022-01-12	2022-01-05	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		3.7801	-1,406	-5		2,224
2022-01-12	2022-01-01	4	Kelly Timothy P	FIXX	Restricted Stock Units	M - Exercise	D			-3,630		7,370
2022-01-12	2022-01-01	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D			3,630			3,630
2022-01-12	2022-01-05	4	Cohn Gabriel	FIXX	Common Stock	S - Sale	D		3.7801	-1,661	-6		2,629
2022-01-12	2022-01-01	4	Cohn Gabriel	FIXX	Restricted Stock Units	M - Exercise	D			-4,290		8,710
2022-01-12	2022-01-01	4	Cohn Gabriel	FIXX	Common Stock	M - Exercise	D			4,290			4,290
2022-01-12	2022-01-05	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		3.7802	-5,354	-20		86,011
2022-01-12	2022-01-01	4	TZIANABOS ARTHUR	FIXX	Restricted Stock Units	M - Exercise	D			-13,860		28,140
2022-01-12	2022-01-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	M - Exercise	D			13,860			91,365
2021-09-08	2021-09-03	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		7.7000	-54	-0		0
2021-09-08	2021-03-01	4/A	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		11.1622	-6,232	-70		0
2021-06-22	2021-06-17	4	Gregory Richard J.	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	Poulton Jeffrey V.	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	Patterson Matthew R	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	REICIN ALISE	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	PARMAR KUSH	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	GILLIS STEVEN	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-06-22	2021-06-17	4	Thistle Mary	FIXX	Option (Right to Buy)	A - Award	D	7.26		18,000		18,000
2021-04-09	2021-04-07	4	Kelly Timothy P	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	7.18		10,000		10,000
2021-03-03	2021-03-01	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	6.63		-2,000		32,001
2021-03-03	2021-03-01	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	2.89		-2,000		32,001
2021-03-03	2021-03-01	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		11.1622	6,232	70		0
2021-03-03	2021-03-01	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		2.8947	2,000	6		6,232
2021-03-03	2021-03-01	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		6.6314	2,000	13		4,232
2021-02-09	2021-02-05	4	Seymour Albert	FIXX	Restricted Stock Units	A - Award	D			13,000		13,000
2021-02-09	2021-02-05	4	Seymour Albert	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	13.78		78,000		78,000
2021-02-09	2021-02-05	4	Kelly Timothy P	FIXX	Restricted Stock Units	A - Award	D			11,000		11,000
2021-02-09	2021-02-05	4	Kelly Timothy P	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	13.78		65,000		65,000
2021-02-09	2021-02-05	4	Cohn Gabriel	FIXX	Restricted Stock Units	A - Award	D			13,000		13,000
2021-02-09	2021-02-05	4	Cohn Gabriel	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	13.78		78,000		78,000
2021-02-09	2021-02-08	4	Smith W Bradford	FIXX	Employee Stock Option (Right to Buy)	M - Exercise	D	0.64		-13,500		101,904
2021-02-09	2021-02-08	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		14.2537	-13,500	-192		0
2021-02-09	2021-02-08	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	13,500	9		13,500
2021-02-09	2021-02-05	4	Smith W Bradford	FIXX	Restricted Stock Units	A - Award	D			20,000		20,000
2021-02-09	2021-02-05	4	Smith W Bradford	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	13.78		122,000		122,000
2021-02-09	2021-02-05	4	TZIANABOS ARTHUR	FIXX	Restricted Stock Units	A - Award	D			42,000		42,000
2021-02-09	2021-02-05	4	TZIANABOS ARTHUR	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	13.78		254,000		254,000
2021-02-05	2021-02-02	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	6.63		-500		44,500
2021-02-05	2021-02-02	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		13.0000	-500	-6		0
2021-02-05	2021-02-02	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		6.6314	500	3		500
2021-02-03	2021-02-01	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	2.89		-2,000		34,001
2021-02-03	2021-02-01	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	6.63		-2,000		34,001
2021-02-03	2021-02-01	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		12.3650	-4,000	-49		0
2021-02-03	2021-02-01	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		2.8947	2,000	6		4,000
2021-02-03	2021-02-01	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		6.6314	2,000	13		2,000
2021-01-14	2021-01-12	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	6.63		-500		45,000
2021-01-14	2021-01-12	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		13.0000	-500	-6		0
2021-01-14	2021-01-12	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		6.6314	500	3		500
2021-01-08	2021-01-07	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		12.0457	-5,103	-61		129,017
2021-01-08	2021-01-06	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		12.0638	-9,897	-119		134,120
2021-01-07	2021-01-05	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		11.4422	-10,000	-114		144,017
2021-01-06	2021-01-04	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	2.89		-2,000		36,001
2021-01-06	2021-01-04	4	Kelly Timothy P	FIXX	Employee Stock Options	M - Exercise	D	6.63		-2,000		36,001
2021-01-06	2021-01-04	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		11.4957	-4,000	-46		0
2021-01-06	2021-01-04	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		2.8947	2,000	6		4,000
2021-01-06	2021-01-04	4	Kelly Timothy P	FIXX	Common Stock	M - Exercise	D		6.6314	2,000	13		2,000
2020-12-28	2020-12-22	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		12.8200	-20,000	-256		181,435
2020-12-28	2020-12-22	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		12.8200	-480,000	-6,154		4,354,484
2020-12-28	2020-12-22	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		12.8200	-20,000	-256		181,435
2020-12-28	2020-12-22	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		12.8200	-480,000	-6,154		4,354,484
2020-12-16	2020-12-14	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		11.8800	-13,703	-163		201,435
2020-12-16	2020-12-14	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		13.0609	-6,297	-82		215,138
2020-12-16	2020-12-14	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		11.8800	-328,862	-3,907		4,834,484
2020-12-16	2020-12-14	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		13.0609	-151,138	-1,974		5,163,346
2020-12-16	2020-12-14	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		11.8800	-13,703	-163		201,435
2020-12-16	2020-12-14	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		13.0609	-6,297	-82		215,138
2020-12-16	2020-12-14	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		11.8800	-328,862	-3,907		4,834,484
2020-12-16	2020-12-14	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		13.0609	-151,138	-1,974		5,163,346
2020-07-21	2020-07-21	4	Poulton Jeffrey V.	FIXX	Option (Right to Buy)	A - Award	D	16.48		36,000		36,000
2020-06-12	2020-06-10	4	PARMAR KUSH	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-06-12	2020-06-10	4	REICIN ALISE	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-06-12	2020-06-10	4	GILLIS STEVEN	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-06-12	2020-06-10	4	Patterson Matthew R	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-06-12	2020-06-10	4	Thistle Mary	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-06-12	2020-06-10	4	Gregory Richard J.	FIXX	Option (Right to Buy)	A - Award	D	16.32		18,000		18,000
2020-03-18	2020-03-17	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		13.0103	-1,315	-17		0
2020-02-05	2020-02-03	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		16.1617	-12,500	-202		77,505
2020-02-05	2020-02-03	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-12,000		103,404
2020-02-05	2020-02-03	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		16.1555	-12,000	-194		0
2020-02-05	2020-02-03	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6316	12,000	8		12,000
2020-01-31	2020-01-30	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	S - Sale	I		15.4500	-509,970	-7,879		0
2020-01-31	2020-01-29	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	S - Sale	I		15.4463	-8,857	-137		509,970
2020-01-29	2019-11-18	4	Gregory Richard J.	FIXX	Employee Stock Option	M - Exercise	D	0.03		-10,806		0
2020-01-29	2019-11-18	4	Gregory Richard J.	FIXX	COMMON STOCK	M - Exercise	D		0.0300	10,806	0		10,806
2020-01-28	2020-01-28	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	S - Sale	I		15.5095	-65,891	-1,022		518,827
2020-01-28	2020-01-27	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	S - Sale	I		15.7717	-193,359	-3,050		584,718
2020-01-28	2020-01-24	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	S - Sale	I		15.6868	-380,256	-5,965		778,077
2020-01-03	2020-01-02	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		115,404
2020-01-03	2020-01-02	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		20.4974	-6,000	-123		0
2020-01-03	2020-01-02	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6316	6,000	4		6,000
2020-01-03	2020-01-02	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		20.4989	-9,133	-187		154,017
2020-01-03	2020-01-02	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		20.4953	-12,500	-256		90,005
2019-12-27	2019-12-24	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	S - Sale	I		21.9501	-151,233	-3,320		1,766,106
2019-12-27	2019-12-24	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	S - Sale	I		21.9501	-198,767	-4,363		2,321,199
2019-12-23	2019-12-23	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	S - Sale	I		21.8294	-56,595	-1,235		1,917,339
2019-12-23	2019-12-23	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	S - Sale	I		21.8294	-74,384	-1,624		2,519,966
2019-12-23	2019-12-20	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	S - Sale	I		21.5002	-9,130	-196		1,973,934
2019-12-23	2019-12-20	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	S - Sale	I		21.5002	-11,999	-258		2,594,350
2019-12-23	2019-12-19	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	S - Sale	I		21.6756	-5,454	-118		1,983,064
2019-12-23	2019-12-19	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	S - Sale	I		21.6756	-7,168	-155		2,606,349
2019-12-13	2019-12-11	4	Smith W Bradford	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	19.92		111,000		111,000
2019-12-13	2019-12-11	4	Kelly Timothy P	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	19.92		112,000		112,000
2019-12-13	2019-12-11	4	Seymour Albert	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	19.92		110,000		110,000
2019-12-13	2019-12-11	4	Cohn Gabriel	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	19.92		15,000		15,000
2019-12-13	2019-12-11	4	TZIANABOS ARTHUR	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	19.92		358,000		358,000
2019-12-03	2019-12-02	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		16.2333	-9,300	-151		163,150
2019-12-03	2019-11-29	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		16.0634	-9,300	-149		172,450
2019-12-03	2019-12-02	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		16.2541	-12,500	-203		102,505
2019-12-03	2019-11-29	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		16.0447	-12,500	-201		115,005
2019-12-03	2019-12-02	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		121,404
2019-12-03	2019-12-02	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		16.2110	-6,000	-97		0
2019-12-03	2019-12-02	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-12-03	2019-11-29	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		127,404
2019-12-03	2019-11-29	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		16.0000	-6,000	-96		0
2019-12-03	2019-11-29	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-12-03	2019-12-02	4	Cohn Gabriel	FIXX	Employee Stock Option (Right to Buy)	A - Award	D	17.14		120,000		120,000
2019-10-02	2019-10-01	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		18.2300	-100	-2		181,750
2019-10-02	2019-10-01	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		17.3844	-9,200	-160		181,850
2019-10-02	2019-10-01	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		133,404
2019-10-02	2019-10-01	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		18.2300	-100	-2		0
2019-10-02	2019-10-01	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		17.3803	-5,900	-103		100
2019-10-02	2019-10-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-10-02	2019-10-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		18.2300	-100	-2		127,505
2019-10-02	2019-10-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		17.3907	-12,400	-216		127,605
2019-09-09	2019-09-05	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		19.9412	-1,166	-23		0
2019-09-05	2019-09-03	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		18.7456	-12,500	-234		140,005
2019-09-05	2019-09-03	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		18.7402	-9,300	-174		191,050
2019-09-05	2019-09-03	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		139,404
2019-09-05	2019-09-03	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		18.7365	-6,000	-112		0
2019-09-05	2019-09-03	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-08-05	2019-08-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		17.3689	-12,500	-217		152,505
2019-08-05	2019-08-01	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		145,404
2019-08-05	2019-08-01	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		17.3651	-6,000	-104		0
2019-08-05	2019-08-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-08-05	2019-08-01	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		17.3681	-9,300	-162		200,350
2019-07-15	2019-07-11	4	REICIN ALISE	FIXX	Option (Right to Buy)	A - Award	D	19.25		31,160		31,160
2019-07-11	2019-07-09	4	Rasty Siyamak	FIXX	Common Stock	S - Sale	D		20.0000	-8,000	-160		222,707
2019-07-03	2019-07-01	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		18.9840	-12,500	-237		165,005
2019-07-03	2019-07-01	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		151,404
2019-07-03	2019-07-01	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		18.9952	-6,000	-114		0
2019-07-03	2019-07-01	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-07-03	2019-07-01	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		19.5600	-100	-2		209,650
2019-07-03	2019-07-01	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		18.9764	-9,200	-175		209,750
2019-06-11	2019-06-06	4/A	Wheeler Cameron	FIXX	Option (Right to Buy)	A - Award	I	19.51		15,580		15,580
2019-06-11	2019-06-06	4	Flynn James E Through Deerfield Management Company, L.P.	FIXX	Stock Option (Right to Buy)	A - Award	I	19.51		15,580		15,580
2019-06-10	2019-06-06	4	GILLIS STEVEN	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-10	2019-06-06	4	PARMAR KUSH	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-10	2019-06-06	4	Patterson Matthew R	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-10	2019-06-06	4	Thistle Mary	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-10	2019-06-06	4	Wheeler Cameron	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-10	2019-06-06	4	Gregory Richard J.	FIXX	Option (Right to Buy)	A - Award	D	19.51		15,580		15,580
2019-06-05	2019-06-03	4	Rasty Siyamak	FIXX	Common Stock	S - Sale	D		20.2222	-8,000	-162		230,707
2019-06-05	2019-06-03	4	TZIANABOS ARTHUR	FIXX	Common Stock	S - Sale	D		19.8610	-12,500	-248		177,505
2019-06-05	2019-06-03	4	Seymour Albert	FIXX	Common Stock	S - Sale	D		19.9025	-9,300	-185		218,950
2019-06-05	2019-06-03	4	Kelly Timothy P	FIXX	Common Stock	S - Sale	D		20.0038	-1,288	-26		0
2019-06-05	2019-06-03	4	Smith W Bradford	FIXX	Employee Stock Option	M - Exercise	D	0.64		-6,000		157,404
2019-06-05	2019-06-03	4	Smith W Bradford	FIXX	Common Stock	S - Sale	D		19.9440	-6,000	-120		0
2019-06-05	2019-06-03	4	Smith W Bradford	FIXX	Common Stock	M - Exercise	D		0.6400	6,000	4		6,000
2019-05-23	2019-05-21	4	ARCH Venture Fund VIII, L.P.	FIXX	Common Stock	J - Other	D			-300,001			5,768,694
2019-05-20	2019-05-16	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		21.4700	-24,600	-528		221,435
2019-05-20	2019-05-16	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		21.4700	-590,400	-12,676		5,314,484
2019-05-20	2019-05-16	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		21.4700	-24,600	-528		221,435
2019-05-20	2019-05-16	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		21.4700	-590,400	-12,676		5,314,484
2019-04-15	2019-04-12	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	P - Purchase	I		22.5000	533,333	12,000		1,158,333
2018-12-18	2018-12-14	4	TZIANABOS ARTHUR	FIXX	Employee stock option	A - Award	D	24.28		203,000		203,000
2018-12-18	2018-12-14	4	Kelly Timothy P	FIXX	Employee stock option	A - Award	D	24.28		66,000		66,000
2018-12-18	2018-12-14	4	Seymour Albert	FIXX	Employee stock option	A - Award	D	24.28		74,000		74,000
2018-12-18	2018-12-14	4	Smith W Bradford	FIXX	Employee stock option	A - Award	D	24.28		88,000		88,000
2018-12-12	2018-12-10	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		26.0051	-623	-16		246,035
2018-12-12	2018-12-10	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		26.0051	-14,952	-389		5,904,884
2018-12-12	2018-12-10	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		26.0051	-623	-16		246,035
2018-12-12	2018-12-10	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		26.0051	-14,952	-389		5,904,884
2018-11-27	2018-11-23	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		20.0360	-1,187	-24		246,658
2018-11-27	2018-11-23	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		20.0360	-28,495	-571		5,919,836
2018-11-27	2018-11-23	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		20.0360	-1,187	-24		246,658
2018-11-27	2018-11-23	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		20.0360	-28,495	-571		5,919,836
2018-11-20	2018-11-16	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		20.2000	-21,036	-425		247,845
2018-11-20	2018-11-16	4	5AM Ventures IV, L.P.	FIXX	Common Stock	S - Sale	I		20.2000	-504,864	-10,198		5,948,331
2018-11-20	2018-11-16	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		20.2000	-21,036	-425		247,845
2018-11-20	2018-11-16	4	PARMAR KUSH	FIXX	Common Stock	S - Sale	I		20.2000	-504,864	-10,198		5,948,331
2018-05-16	2018-04-02	4/A	SHAH MAHENDRA	FIXX	Common Stock	A - Award	I		16.0000	250,000	4,000		909,742
2018-04-04	2018-04-02	4/A	PARMAR KUSH	FIXX	Common Stock	C - Conversion	I			5,392,037			6,722,076
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Series B Preferred Stock	C - Conversion	I			-6,944,444		0
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Series B Preferred Stock	C - Conversion	I			-6,944,445		0
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Series A Preferred Stock	C - Conversion	I			-3,521,126		0
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Series A Preferred Stock	C - Conversion	I			-3,521,126		0
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	P - Purchase	I		16.0000	625,000	10,000		625,000
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Partners, L.P.	FIXX	Common Stock	P - Purchase	I		16.0000	625,000	10,000		625,000
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	C - Conversion	I			1,319,483			1,988,517
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	C - Conversion	I			1,319,484			1,988,518
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Private Design Fund III, L.P.	FIXX	Common Stock	C - Conversion	I			669,034			669,034
2018-04-04	2018-04-02	4	Flynn James E Through Deerfield Healthcare Innovations Fund, L.P.	FIXX	Common Stock	C - Conversion	I			669,034			669,034
2018-04-04	2018-04-02	4	5AM Ventures IV, L.P.	FIXX	Series B Preferred Stock	C - Conversion	I			-1,187,535		0
2018-04-04	2018-04-02	4	5AM Ventures IV, L.P.	FIXX	Series A Preferred Stock	C - Conversion	I			-4,204,502		0
2018-04-04	2018-04-02	4	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock	C - Conversion	I			5,392,037			6,722,076
2018-04-04	2018-04-02	4	SHAH MAHENDRA	FIXX	Series B Preferred Stock	C - Conversion	I			-659,742		0
2018-04-04	2018-04-02	4	SHAH MAHENDRA	FIXX	Common Stock	A - Award	I		16.0000	500,000	8,000		1,159,742
2018-04-04	2018-04-02	4	SHAH MAHENDRA	FIXX	Common Stock	C - Conversion	I			659,742			659,742
2018-04-04	2018-04-02	4	Vida Ventures, LLC	FIXX	Series B Preferred Stock	C - Conversion	I			-395,845		0
2018-04-04	2018-04-02	4	Vida Ventures, LLC	FIXX	Common Stock	P - Purchase	I		16.0000	375,000	6,000		770,845
2018-04-04	2018-04-02	4	Vida Ventures, LLC	FIXX	Common Stock	C - Conversion	I			395,845			395,845
2018-04-04	2018-04-02	4	Rock Springs Capital Management LP	FIXX	Series B Preferred Stock	C - Conversion	I			-395,845		0
2018-04-04	2018-04-02	4	Rock Springs Capital Management LP	FIXX	Common Stock	P - Purchase	I		16.0000	250,000	4,000		645,845
2018-04-04	2018-04-02	4	Rock Springs Capital Management LP	FIXX	Common Stock	C - Conversion	I			395,845			395,845
2018-04-04	2018-04-02	4	Novartis Institutes for BioMedical Research, Inc.	FIXX	Series B Preferred Stock	C - Conversion	D			-1,979,226		0
2018-04-04	2018-04-02	4	Novartis Institutes for BioMedical Research, Inc.	FIXX	Common Stock	C - Conversion	D			1,979,226			1,979,226
2018-04-04	2018-04-02	4	PARMAR KUSH	FIXX	Series B Preferred Stock	C - Conversion	I			-1,187,535		0
2018-04-04	2018-04-02	4	PARMAR KUSH	FIXX	Series A Preferred Stock	C - Conversion	I			-4,204,502		0
2018-04-04	2018-04-02	4	PARMAR KUSH	FIXX	Common Stock	C - Conversion	I			5,392,037			6,722,076
2018-04-04	2018-04-02	4	ARCH Venture Fund VIII, L.P.	FIXX	Series B Preferred Stock	C - Conversion	I			-1,385,457		0
2018-04-04	2018-04-02	4	ARCH Venture Fund VIII, L.P.	FIXX	Series A Preferred Stock	C - Conversion	I			-4,683,238		0
2018-04-04	2018-04-02	4	ARCH Venture Fund VIII, L.P.	FIXX	Common Stock	C - Conversion	I			6,068,695			6,068,695
2018-04-04	2018-04-02	4	GILLIS STEVEN	FIXX	Series B Preferred Stock	C - Conversion	I			-1,385,457		0
2018-04-04	2018-04-02	4	GILLIS STEVEN	FIXX	Series A Preferred Stock	C - Conversion	I			-4,683,238		0
2018-04-04	2018-04-02	4	GILLIS STEVEN	FIXX	Common Stock	C - Conversion	I			6,068,695			6,068,695
2018-04-04	2018-04-02	4	Temasek Holdings (Private) Ltd See footnotes	FIXX	Series B Preferred Stock	C - Conversion	I			-989,612		0
2018-04-04	2018-04-02	4	Temasek Holdings (Private) Ltd See footnotes	FIXX	Series A Preferred Stock	C - Conversion	I			-1,605,681		0
2018-04-04	2018-04-02	4	Temasek Holdings (Private) Ltd	FIXX	Common Stock	P - Purchase	I		16.0000	625,000	10,000		3,220,293
2018-04-04	2018-04-02	4	Temasek Holdings (Private) Ltd	FIXX	Common Stock	C - Conversion	I			989,612			2,595,293
2018-04-04	2018-04-02	4	Temasek Holdings (Private) Ltd	FIXX	Common Stock	C - Conversion	I			1,605,681			1,605,681
2018-03-29	2018-03-27	4	Gregory Richard J.	FIXX	Employee stock option	A - Award	D	16.00		31,160		31,160
2018-03-29	2018-03-27	4	PARMAR KUSH	FIXX	Employee stock option	A - Award	D	16.00		31,160		31,160
2018-03-29	2018-03-27	4	Seymour Albert	FIXX	Employee stock option	A - Award	D	16.00		66,501		66,501
2018-03-29	2018-03-27	4	Wheeler Cameron	FIXX	Employee stock option	A - Award	I	16.00		31,160		31,160
2018-03-29	2018-03-27	4	TZIANABOS ARTHUR	FIXX	Employee stock option	A - Award	D	16.00		92,376		92,376
2018-03-29	2018-03-27	4	Thistle Mary	FIXX	Employee stock option	A - Award	D	16.00		31,160		31,160
2018-03-29	2018-03-27	4	Rasty Siyamak	FIXX	Employee stock option	A - Award	D	16.00		30,780		30,780
2018-03-29	2018-03-27	4	Patterson Matthew R	FIXX	Employee stock option	A - Award	D	16.00		8,360		8,360
2018-03-29	2018-03-27	4	Smith W Bradford	FIXX	Employee stock option	A - Award	D	16.00		49,711		49,711
2018-03-29	2018-03-27	4	SHAH MAHENDRA	FIXX	Employee stock options	A - Award	D	16.00		31,160		31,160
2018-03-29	2018-03-27	4	GILLIS STEVEN	FIXX	Employee stock option	A - Award	D	16.00		31,160		31,160
2018-03-29	2018-03-27	4	Flynn James E Through Deerfield Management Company, L.P.	FIXX	Stock Option (Right to Buy)	A - Award	I	16.00		31,160		31,160
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	5AM Ventures IV, L.P. See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	Seymour Albert	FIXX	Common Stock		D						456,500
2018-03-27		3	Seymour Albert	FIXX	Common Stock		D						456,500
2018-03-27		3	Seymour Albert	FIXX	Common Stock		D						456,500
2018-03-27		3	PARMAR KUSH See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	PARMAR KUSH See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	PARMAR KUSH See footnotes	FIXX	Common Stock		I						2,660,078
2018-03-27		3	Chatterjee Saswati	FIXX	Common Stock		D						950,028
2018-03-27		3	Chatterjee Saswati	FIXX	Common Stock		D						950,028
2018-03-27		3	Chatterjee Saswati	FIXX	Common Stock		D						950,028
2018-03-27		3	TZIANABOS ARTHUR	FIXX	Common Stock		D						380,010
2018-03-27		3	TZIANABOS ARTHUR	FIXX	Common Stock		D						380,010
2018-03-27		3	TZIANABOS ARTHUR	FIXX	Common Stock		D						380,010
2018-03-27		3	Rasty Siyamak	FIXX	Common Stock		D						477,414
2018-03-27		3	Rasty Siyamak	FIXX	Common Stock		D						477,414
2018-03-27		3	Rasty Siyamak	FIXX	Common Stock		D						477,414

Open market or private purchase of non-derivative or derivative security

Open market or private sale of non-derivative or derivative security

Grant, award, or other acquisition of securities from the company (such as an option)

Conversion of derivative

Sale or transfer of securities back to the company

Payment of exercise price or tax liability using portion of securities received from the company

Gift of securities by or to the insider

Equity swaps and similar hedging transactions

Exercise or conversion of derivative security received from the company (such as an option)

A transaction voluntarily reported on Form 4

Other (accompanied by a footnote describing the transaction)

QTTB / Q32 Bio Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5