| Shares Outstanding | 126,289,910 shares |
| Insider Shares | 38,975,141 shares |
| Insider Ownership | 30.86 % |
| Total Insiders | 38 |
Insider Sentiment Score
The Insider Sentiment Score finds the companies being bought by corporate insiders.
It is the result of a sophisticated, multi-factor quantitative model that identifies companies with the highest levels of insider accumulation. The scoring model uses a combination of the net number of insiders buying the prior 90 days, the total shares bought as a percentage of float, and the total shares owned by insiders. The number ranges from 0 to 100, with higher numbers indicating a higher level of accumulation to its peers, and 50 being the average.
Update Frequency: Daily
See Insiders Top Picks, which provides a list of companies with highest insider accumulation.
Officer Sentiment Score
The Officer Sentiment Score finds companies being bought by Corporate Officers.
By definition Corporate Officers are Corporate Insiders, but unlike some of the other Insiders (10% Shareholders and Board Members), Officers work for the company on a daily basis, and they user their own money when trading. (10% Shareholders and Board Members are often fund managers managing other people’s money.) As such, insider trades made by Officers are much more significant and should be treated appropriately.
Like the Insider Sentiment Score, the Officer Sentiment Score is the result of a sophisticated, multi-factor quantitative model that identifies companies with the highest levels of officer accumulation.
Update Frequency: Daily
See Insiders Top Picks, which provides a list of companies with highest insider sentiment.
Key Insider Metrics
This card shows how the company ranks along various insider metrics. The percentile rank shows how this company compares to other companies in the US markets. Higher rankings are indicative of better situations.
For example, it is generally accepted that insider buying is a positive indicator, so companies with more insider buying would rank higher than companies with less insider buying (or even insider selling).
Insider Trading Chart
Apellis Pharmaceuticals, Inc. insider trades are shown in the following chart. Insiders are officers, directors, or significant investors in a company. In general, it is generally illegal for insiders to make trades in their companies based on material, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4.
Insider Roster and Profitability Metrics
This table shows the list known insiders, and is generated automatically from filings disclosed to the SEC. In addition to the names, most recent title, and director, officer, or 10% owner designation, we provide the latest disclosed holdings. Additionally, when possible we provide the historical trade performance for the insider. The historical trade performance is a weighted average of the performance of actual open-market purchase transactions made by the insider. For more information on how this is calculated, watch this YouTube webinar.
See our leaderboard of most profitable insider traders.
| Insider | Avg Profit (%) | Shares Owned |
Split Adjusted |
|---|---|---|---|
|
AJU IB Investment Co., Ltd.
10% Owner -
|
2,292,062 | 2,292,062 | |
| Steven Axon Chief Business Officer - [O] | 50,110 | 50,110 | |
| Caroline Baumal Chief Medical Officer - [O] | 93,301 | 93,301 | |
| Kelley Boucher Chief People Officer - [O] | 97,658 | 97,658 | |
| Brown Victoria L. Program Team Lead - [O] | 23,556 | 23,556 | |
| Lucia Celona See Remarks - [O] | 5,213 | 5,213 | |
| Gerald Chan Director - [D] | 17,705 | 17,705 | |
|
Bihua Chen
Director, 10% Owner -
[D]
|
3,473,925 | 3,473,925 | |
| James George Chopas VP/Chief Accounting Officer - [O] | 53,657 | 53,657 | |
|
Cormorant Asset Management, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare GP, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare Master Fund, LP
10% Owner -
|
3,473,925 | 3,473,925 |
| Insider | Avg Profit (%) | Shares Owned |
Split Adjusted |
|---|---|---|---|
| Mark Jeffrey DeLong Chief Business & Strat Officer - [O] | 83,945 | 83,945 | |
| Pascal Deschatelets Chief Scientific Officer - [O] | 1,160,496 | 1,160,496 | |
| Dunlop A. Sinclair Director - [D] | 158,393 | 158,393 | |
| Jeffrey Eisele Chief Development Officer - [O] | 55,312 | 55,312 | |
| Fonteyne Paul R. Director - [D] | 22,705 | 22,705 | |
| Cedric Francois Chief Executive Officer, Director - [D] [O] | 1,646,027 | 1,646,027 | |
|
Michael E Gellert
10% Owner -
|
943,989 | 943,989 | |
| Federico Grossi Chief Medical Officer - [O] | 94,884 | 94,884 | |
|
Hillhouse Capital Management, Ltd.
10% Owner -
|
3,527,152 | 3,527,152 | |
| Lackner Thomas A. See Remarks - [O] | 7,725 | 7,725 | |
| Karen Lewis Chief People Officer - [O] | 70,251 | 70,251 | |
| Leslie Meltzer Chief Research and Development - [O] | 61,804 | 61,804 | |
| Alec Machiels Director - [D] | 377,028 | 377,028 |
| Insider | Avg Profit (%) | Shares Owned |
Split Adjusted |
|---|---|---|---|
|
Morningside Venture Investments Ltd
10% Owner -
|
12,806,342 | 12,806,342 | |
| Nur Nicholson Chief Technical Officer - [O] | 83,664 | 83,664 | |
| Stephanie Monaghan O'Brien Director - [D] | 17,705 | 17,705 | |
| Nicole D Perry Vice President - Accounting - [O] | 4,847 | 4,847 | |
|
Potentia Holdings, LLC
10% Owner -
|
7,653,202 | 7,653,202 | |
| Lukas Scheibler Chief Research Officer - [O] | 68,299 | 68,299 | |
| Ahmad Sadr See Remarks - [O] | 2,725 | 2,725 | |
| Timothy Eugene Sullivan Chief Financial Officer - [O] | 128,665 | 128,665 | |
| Townsend Adam J. Chief Commercial Officer - [O] | 84,050 | 84,050 | |
| Craig A Wheeler Director - [D] | 16,483 | 16,483 | |
| Keli Walbert Director - [D] | 9,090 | 9,090 | |
| Watson David O. General Counsel - [O] | 203,866 | 203,866 | |
|
venBio Global Strategic Fund II L.P.
10% Owner -
|
3,579,305 | 3,579,305 |
Report errors via our new Insider Auditing Tool
Track Records of Insider Purchases - Short Term Profit Analysis
In this section, we analyze the profitability of every unplanned, open-market insider purchase made in APLS / Apellis Pharmaceuticals, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical .
The following table shows the most recent open market purchases that were not part of an automatic trading plan.
Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.
Track Records of Insider Sales - Short Term Loss Analysis
In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in APLS / Apellis Pharmaceuticals, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical .
The following table shows the most recent open market sales that were not part of an automatic trading plan.
Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.
Transaction History
Click the link icon to see the full transaction history. Transactions reported as part of a 10b5-1 automatic trading plan will have an X in the column marked 10b-5.
| File Date |
Trade Date |
Form | Insider | Ticker | Security Title | Code | Direct | Exercise Price |
Unit Price |
Units Changed |
Value Changed (1K) |
Remaining Options |
Remaining Shares |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-09-03 | 2025-09-02 | 4 | Chopas James George | APLS | Common Stock | D | 28.0770 | -548 | -15 | 53,657 | ||||
| 2025-09-03 | 2025-09-02 | 4 | Boucher Kelley | APLS | Common Stock | D | 30,476 | 97,658 | ||||||
| 2025-09-02 | 2025-08-26 | 4 | MELTZER LESLIE | APLS | Common Stock | D | 61,804 | 61,804 | ||||||
| 2025-08-29 | 2025-08-28 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.3900 | -49,963 | -1,418 | 307,946 | ||||
| 2025-08-29 | 2025-08-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.1900 | -175,037 | -4,934 | 357,909 | ||||
| 2025-08-19 | 2025-08-18 | 4 | Watson David O. | APLS | Common Stock | D | 27.8000 | -5,000 | -139 | 123,730 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 20.2147 | -19,725 | -399 | 331,605 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 8,997 | 39 | 351,330 | ||||
| 2025-07-18 | 2025-07-16 | 4 | Watson David O. | APLS | Common Stock | D | 19.5500 | -5,000 | -98 | 128,730 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 20.0884 | -1,900 | -38 | 342,333 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 800 | 3 | 344,233 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 20.1864 | -137,465 | -2,775 | 343,433 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 65,203 | 281 | 480,898 | ||||
| 2025-06-20 | 2025-06-18 | 4 | Chopas James George | APLS | Common Stock | D | 6,250 | 54,205 | ||||||
| 2025-06-18 | 2025-06-16 | 4 | Watson David O. | APLS | Common Stock | D | 18.7700 | -5,000 | -94 | 133,730 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Boucher Kelley | APLS | Common Stock | D | 45,095 | 67,182 | ||||||
| 2025-05-29 | 2025-05-28 | 4 | Boucher Kelley | APLS | Common Stock | D | 22,087 | 22,087 | ||||||
| 2025-05-22 | 2025-05-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 12,780 | 48 | 1,160,496 | ||||
| 2025-04-21 | 2025-04-17 | 4 | WHEELER CRAIG A | APLS | Common Stock | D | 16,483 | 16,483 | ||||||
| 2025-03-18 | 2025-03-17 | 4 | Chopas James George | APLS | Common Stock | D | 24.8237 | -183 | -5 | 47,955 | ||||
| 2025-03-06 | 2025-03-05 | 4 | Watson David O. | APLS | Common Stock | D | 25.1013 | -5,569 | -140 | 138,730 | ||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (Custodial Account for Son) | APLS | Common Stock | I | 6,667 | 10,000 | ||||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (The Watson Education Trust) | APLS | Common Stock | I | -6,667 | 0 | ||||||
| 2025-02-12 | 2025-02-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.5388 | -363 | -10 | 83,945 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 144,299 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 84,050 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.5236 | -546 | -16 | 128,665 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.5236 | -825 | -24 | 83,664 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 29.5236 | -364 | -11 | 70,251 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 29.5236 | -278 | -8 | 55,312 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.5236 | -826 | -24 | 1,147,716 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 29.5236 | -2,824 | -83 | 415,695 | ||||
| 2025-01-30 | 2025-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.5236 | -365 | -11 | 84,308 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 144,994 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 84,745 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30.4255 | -3,088 | -94 | 129,211 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 84,489 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 30.4255 | -1,751 | -53 | 70,615 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 30.4255 | -13,551 | -412 | 418,519 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 30.4255 | -1,291 | -39 | 55,590 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 1,148,542 | ||||
| 2025-01-23 | 2025-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 30.4255 | -1,396 | -42 | 84,673 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 30.4255 | -1,096 | -33 | 48,138 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 42,762 | 148,317 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Watson David O. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 105,555 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 88,068 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 45,929 | 132,299 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.9582 | -1,730 | -52 | 86,370 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 36,426 | 88,437 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.9582 | -2,145 | -64 | 52,011 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 28,508 | 72,366 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 29.9582 | -1,241 | -37 | 43,858 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 130,662 | 432,070 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9582 | -6,007 | -180 | 301,408 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 15,045 | 1,152,490 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.9582 | -750 | -22 | 1,137,445 | ||||
| 2025-01-21 | 2025-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28,508 | 86,069 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.9582 | -1,235 | -37 | 57,561 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 12,591 | 49,234 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Chopas James George | APLS | Common Stock | D | 29.9582 | -715 | -21 | 36,643 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Baumal Caroline | APLS | Common Stock | D | 39,594 | 93,301 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Baumal Caroline | APLS | Common Stock | D | 29.9582 | -1,853 | -56 | 53,707 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Watson David O. | APLS | Common Stock | D | 28.7021 | -4,965 | -143 | 107,756 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Townsend Adam J. | APLS | Common Stock | D | 28.7021 | -2,685 | -77 | 90,269 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 28.7021 | -2,170 | -62 | 88,100 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 28.7021 | -2,632 | -76 | 54,156 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Lewis Karen | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 45,099 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Francois Cedric | APLS | Common Stock | D | 28.7021 | -6,247 | -179 | 307,415 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 28.7021 | -264 | -8 | 56,881 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 28.7021 | -2,288 | -66 | 1,138,195 | ||||
| 2025-01-14 | 2025-01-13 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 58,796 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Chopas James George | APLS | Common Stock | D | 28.7021 | -783 | -22 | 37,358 | ||||
| 2025-01-10 | 2025-01-08 | 4 | Walbert Keli | APLS | Common Stock | D | 9,090 | 9,090 | ||||||
| 2025-01-08 | 2025-01-06 | 4 | Baumal Caroline | APLS | Common Stock | D | 33.8120 | -2,816 | -95 | 55,560 | ||||
| 2025-01-03 | 2025-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 6,267 | 377,028 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 6,267 | 22,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 6,267 | 158,393 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 13.8500 | 10,054 | 139 | 90,270 | ||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 14.9500 | 1,042 | 16 | 80,216 | ||||
| 2024-12-27 | 2024-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 33.0900 | -63 | -2 | 57,145 | ||||
| 2024-12-13 | 2024-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 34.2350 | -5,000 | -171 | 112,721 | ||||
| 2024-11-01 | 2024-11-01 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | -182,146 | 472,065 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. | APLS | Common Stock | D | 10,569 | 117,721 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | -10,569 | 70,136 | ||||||
| 2024-09-24 | 2024-09-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,600 | 61 | 152,126 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.7900 | -7,524 | -277 | 100,000 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.0900 | -29,476 | -1,064 | 107,524 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Chopas James George | APLS | Common Stock | D | 36.2060 | -192 | -7 | 38,141 | ||||
| 2024-09-04 | 2024-09-03 | 4 | Chopas James George | APLS | Common Stock | D | 39.4910 | -550 | -22 | 38,333 | ||||
| 2024-08-13 | 2024-08-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 5,201 | 72 | 60,395 | ||||
| 2024-07-01 | 2024-06-28 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 900 | 12 | 134,418 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.6300 | -1,695 | -67 | 136,998 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.2200 | -35,305 | -1,385 | 138,693 | ||||
| 2024-05-21 | 2024-05-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 24,500 | 92 | 1,140,483 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0250 | -100 | -4 | 1,115,983 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8490 | -22,472 | -963 | 1,116,083 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.1504 | -56,335 | -2,375 | 1,138,555 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 4.3100 | 78,907 | 340 | 1,194,890 | ||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 14,164 | 70,396 | ||||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -14,164 | 79,174 | ||||||
| 2024-04-15 | 2024-04-12 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 1,500 | 20 | 133,518 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.9152 | -4,728 | -260 | 1,115,983 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.1165 | -64,379 | -3,484 | 1,120,711 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 69,107 | 260 | 1,185,090 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.6600 | -4,000 | -235 | 93,338 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 4,000 | 40 | 97,338 | ||||
| 2024-03-20 | 2024-03-19 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 57.1790 | -18,681 | -1,068 | 173,998 | ||||
| 2024-03-19 | 2024-03-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.9000 | -9,913 | -564 | 54,693 | ||||
| 2024-03-18 | 2024-03-15 | 4 | Chopas James George | APLS | Common Stock | D | 56.4610 | -184 | -10 | 38,883 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.1335 | -3,452 | -201 | 56,287 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 57.3070 | -7,768 | -445 | 59,739 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.3500 | -100 | -6 | 1,115,983 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.6896 | -26,257 | -1,646 | 1,116,083 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 61.8754 | -42,750 | -2,645 | 1,142,340 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 69,107 | 254 | 1,185,090 | ||||
| 2024-03-08 | 2024-03-06 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 3,762 | 52 | 107,152 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 65.6800 | -413 | -27 | 313,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9163 | -116,512 | -7,564 | 314,075 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.2573 | -62,503 | -4,016 | 430,587 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.9631 | -41,704 | -2,626 | 493,090 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.2130 | -28,868 | -1,796 | 534,794 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 200,000 | 862 | 563,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 50,000 | 188 | 363,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 63.9500 | -2,000 | -128 | 93,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 62.8600 | -4,000 | -251 | 95,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,000 | 60 | 99,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Watson David O. | APLS | Common Stock | D | 67.7669 | -781 | -53 | 103,390 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 92,453 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 67.7669 | -1,431 | -97 | 93,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Francois Cedric | APLS | Common Stock | D | 67.7669 | -3,962 | -268 | 313,662 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 1,115,983 | ||||
| 2024-02-13 | 2024-02-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.7669 | -597 | -40 | 64,606 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 104,171 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 93,601 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.1382 | -906 | -58 | 94,769 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.1382 | -874 | -56 | 1,117,131 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5300 | -971 | -64 | 57,208 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.1382 | -279 | -18 | 58,179 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.1382 | -835 | -54 | 67,507 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 64.1382 | -2,843 | -182 | 317,624 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5300 | -883 | -58 | 46,387 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 64.1382 | -367 | -24 | 47,270 | ||||
| 2024-01-31 | 2024-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.1382 | -367 | -24 | 65,203 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 63.6900 | -4,286 | -273 | 47,637 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 63.6900 | -7,378 | -470 | 58,458 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9960 | -13,431 | -873 | 320,467 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 64.9960 | -4,184 | -272 | 105,077 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.9960 | -3,413 | -222 | 94,507 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.9960 | -3,551 | -231 | 95,675 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.9960 | -2,593 | -169 | 68,342 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 64.9960 | -1,738 | -113 | 51,923 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.9960 | -1,607 | -104 | 65,836 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.9960 | -3,913 | -254 | 1,118,005 | ||||
| 2024-01-23 | 2024-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9960 | -1,384 | -90 | 65,570 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 64.9960 | -1,061 | -69 | 39,067 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5800 | -5,207 | -341 | 67,443 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5800 | -3,276 | -215 | 53,661 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 1,121,918 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 6,743 | 1,123,550 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 66.8086 | -864 | -58 | 40,128 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 8,312 | 40,992 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 56,937 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 16,963 | 58,569 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 66.8086 | -1,631 | -109 | 66,954 | ||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 16,963 | 68,585 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 66.8086 | -1,857 | -124 | 70,935 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 19,508 | 72,792 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 66.8086 | -4,240 | -283 | 109,261 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 23,748 | 113,501 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 97,920 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 23,748 | 100,155 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 99,226 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 23,748 | 101,461 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Baumal Caroline | APLS | Common Stock | D | 25,445 | 58,376 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 66.8086 | -7,851 | -525 | 333,898 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 72,094 | 341,749 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 66.8086 | -438 | -29 | 72,650 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 19,508 | 73,088 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Baumal Caroline | APLS | Common Stock | D | 60.0534 | -2,751 | -165 | 32,931 | ||||
| 2024-01-02 | 2024-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,341 | 16,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,341 | 132,018 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,341 | 370,761 | ||||||
| 2023-12-28 | 2023-12-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 60.2300 | -235 | -14 | 53,580 | ||||
| 2023-12-28 | 2023-12-26 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 57.8609 | -68 | -4 | 53,815 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.3827 | -2,300 | -132 | 89,753 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.0041 | -1,605 | -91 | 92,053 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 7,905 | 109 | 93,658 | ||||
| 2023-12-15 | 2023-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 6,274 | 83 | 128,677 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -10,000 | -600 | 68,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 78,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 61.3052 | -42,443 | -2,602 | 76,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.5019 | -67,557 | -4,087 | 118,850 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 110,000 | 1,660 | 186,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 61.1350 | -24,000 | -1,467 | 192,679 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7866 | -300 | -16 | 77,713 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7300 | -13,858 | -758 | 78,013 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 14,158 | 142 | 91,871 | ||||
| 2023-11-21 | 2023-11-21 | 4 | Francois Cedric | APLS | Common Stock | D | 48.8000 | -5,000 | -244 | 269,655 | ||||
| 2023-11-21 | 2023-10-17 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 49.0000 | -24,000 | -1,176 | 216,679 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9910 | -8,894 | -445 | 122,403 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 47.7400 | -1,250 | -60 | 367,420 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-11-15 | 2023-11-14 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 45,000 | 169 | 1,116,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.2700 | -12,000 | -567 | 1,071,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 17,494 | 47 | 1,083,807 | ||||
| 2023-10-24 | 2023-10-23 | 4 | Chopas James George | APLS | Common Stock | D | 46.0362 | -132 | -6 | 32,680 | ||||
| 2023-10-24 | 2023-10-23 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 46.0362 | -131 | -6 | 51,622 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 48.5000 | -1,250 | -61 | 367,420 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.3800 | -12,000 | -485 | 1,066,313 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,078,313 | ||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 150,000 | 804,211 | ||||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric | APLS | Common Stock | D | -150,000 | 274,655 | ||||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 45.0000 | -1,250 | -56 | 367,420 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 46.1470 | -10,631 | -491 | 53,284 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 42.2085 | -9,719 | -410 | 63,915 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.7600 | 9,719 | 289 | 73,634 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3400 | -1,250 | -57 | 367,420 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-18 | 2023-09-14 | 4 | Chopas James George | APLS | Common Stock | D | 2,500 | 32,812 | ||||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8700 | -12,000 | -514 | 1,059,813 | ||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,071,813 | ||||
| 2023-09-07 | 2023-09-06 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0100 | -1,756 | -76 | 68,299 | ||||
| 2023-09-01 | 2023-08-31 | 4 | Chopas James George | APLS | Common Stock | D | 41.2260 | -551 | -23 | 30,312 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 42.4400 | -10,284 | -436 | 424,655 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 41.7025 | -139,716 | -5,827 | 434,939 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 300,000 | 801 | 574,655 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 23.6600 | -12,000 | -284 | 1,053,313 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,065,313 | ||||
| 2023-07-24 | 2023-07-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 49,779 | 133 | 367,420 | ||||
| 2023-07-21 | 2023-07-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 50,000 | 134 | 317,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.7900 | -1,250 | -81 | 267,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 84.5500 | -12,000 | -1,015 | 1,046,813 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,058,813 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 91.0983 | -300 | -27 | 77,713 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.4165 | -3,287 | -297 | 78,013 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.4109 | -3,192 | -285 | 81,300 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,779 | 68 | 84,492 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Watson David O. | APLS | Common Stock | D | 89.9800 | -8,510 | -766 | 85,753 | ||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 12,750 | 80,705 | ||||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. | APLS | Common Stock | D | -12,750 | 94,263 | ||||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 88.4100 | -1,250 | -111 | 267,641 | ||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 91.3500 | -12,000 | -1,096 | 1,040,313 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,052,313 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.8259 | -30,506 | -2,740 | 77,713 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 88.3649 | -7,064 | -624 | 108,219 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 87.7886 | -30,609 | -2,687 | 115,283 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.6044 | -1,600 | -145 | 145,892 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 69,779 | 700 | 147,492 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 86.0000 | -5,000 | -430 | 41,504 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,504 | ||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 654,211 | ||||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric | APLS | Common Stock | D | -20,000 | 274,655 | ||||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 88.6600 | -1,250 | -111 | 267,641 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 294,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.6739 | -2,120 | -186 | 274,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.0163 | -7,528 | -655 | 276,775 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.9012 | -3,007 | -258 | 284,303 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.0089 | -14,611 | -1,242 | 287,310 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.8450 | -1,800 | -151 | 301,921 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.1711 | -934 | -78 | 303,721 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 304,655 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 92.3900 | -12,000 | -1,109 | 1,033,813 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,045,813 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 82.7100 | -5,000 | -414 | 75,995 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 56,232 | ||||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -20,000 | 77,713 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 382,946 | 382,946 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric | APLS | Common Stock | D | -382,946 | 274,655 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 67,955 | 67,955 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -67,955 | 107,013 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 657,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 82.0240 | -30,000 | -2,461 | 637,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 667,601 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 36,232 | 36,232 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -36,232 | 97,713 | ||||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 81.0500 | -1,250 | -101 | 267,641 | ||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 78.2100 | -12,000 | -939 | 1,027,313 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,039,313 | ||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 26,990 | 634,211 | ||||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric | APLS | Common Stock | D | -26,990 | 637,601 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 380,000 | 607,221 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric | APLS | Common Stock | D | -380,000 | 664,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 227,221 | 227,221 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric | APLS | Common Stock | D | -227,221 | 1,044,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 74.0500 | -500 | -37 | 131,297 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 75.0000 | -5,000 | -375 | 41,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 74.0500 | -5,000 | -370 | 75,995 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 13.8500 | 7,221 | 100 | 1,271,812 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,264,591 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 1,164,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 62.7444 | -30,000 | -1,882 | 1,144,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 1,174,591 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.0300 | -1,250 | -80 | 267,641 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.7900 | -12,000 | -765 | 1,020,813 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,032,813 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 63.8400 | -5,000 | -319 | 75,995 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-02 | 2023-03-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 65.3300 | -500 | -33 | 131,797 | ||||
| 2023-03-01 | 2023-02-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,144,591 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 68.7600 | -1,646 | -113 | 53,883 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Lewis Karen | APLS | Common Stock | D | 68.7600 | -1,104 | -76 | 41,430 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 58.5000 | -825 | -48 | 55,529 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 9,886 | 56,354 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 58.5000 | -334 | -20 | 30,863 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 4,044 | 31,197 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 58.5000 | -553 | -32 | 42,534 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 6,628 | 43,087 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 58.5000 | -1,195 | -70 | 1,014,313 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,886 | 1,015,508 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 58.5000 | -825 | -48 | 174,968 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 9,886 | 175,793 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 58.5000 | -715 | -42 | 69,643 | ||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,886 | 70,358 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 58.5000 | -1,602 | -94 | 1,044,591 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 13,908 | 1,046,193 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.5000 | -974 | -57 | 133,945 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,683 | 134,919 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5000 | -1,041 | -61 | 75,995 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,886 | 77,036 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.5000 | -825 | -48 | 63,503 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 9,886 | 64,328 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.5000 | -441 | -26 | 51,341 | ||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 5,280 | 51,782 | ||||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3800 | -1,250 | -65 | 267,641 | ||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 51.2100 | -532 | -27 | 165,907 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 51.2100 | -782 | -40 | 67,150 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 51.2100 | -975 | -50 | 123,236 | ||||
| 2023-02-14 | 2023-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 51.2100 | -678 | -35 | 60,472 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 51.2100 | -3,958 | -203 | 1,032,285 | ||||
| 2023-02-14 | 2023-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 51.2100 | -670 | -34 | 46,502 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 51.2100 | -1,134 | -58 | 1,005,622 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.4500 | -12,000 | -653 | 1,006,756 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,018,756 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 55.8500 | -5,000 | -279 | 67,932 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 72,932 | ||||
| 2023-02-02 | 2023-02-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 52.6100 | -500 | -26 | 132,297 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7600 | -883 | -47 | 46,468 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7600 | -883 | -47 | 36,459 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.7700 | -551 | -29 | 124,211 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 67,932 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 166,439 | ||||
| 2023-01-30 | 2023-01-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.7700 | -542 | -29 | 61,150 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7700 | -367 | -19 | 37,342 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.7700 | -551 | -29 | 54,442 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 52.7700 | -2,879 | -152 | 1,036,243 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,351 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.7700 | -832 | -44 | 1,000,256 | ||||
| 2023-01-30 | 2023-01-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,172 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 51.5800 | -2,955 | -152 | 37,709 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.5800 | -4,479 | -231 | 47,718 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Brown Victoria L. | APLS | Common Stock | D | 52.0500 | -1,412 | -73 | 23,556 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Chopas James George | APLS | Common Stock | D | 52.0500 | -919 | -48 | 27,153 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.0500 | -2,326 | -121 | 1,001,088 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.0500 | -2,033 | -106 | 52,197 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.0500 | -2,379 | -124 | 124,762 | ||||
| 2023-01-24 | 2023-01-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.0500 | -1,149 | -60 | 47,539 | ||||
| 2023-01-24 | 2023-01-20 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.0500 | -2,015 | -105 | 61,692 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0500 | -9,453 | -492 | 1,039,122 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Lewis Karen | APLS | Common Stock | D | 52.0500 | -1,411 | -73 | 40,664 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 54,993 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.0500 | -1,912 | -100 | 68,483 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Watson David O. | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 166,990 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.4200 | -1,250 | -66 | 267,641 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-01-17 | 2023-01-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 27,488 | 127,141 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -3,750 | 99,653 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 22,580 | 63,707 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Francois Cedric | APLS | Common Stock | D | 83,447 | 1,048,575 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 29,452 | 169,024 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 24,003 | 139,572 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 19,634 | 1,003,414 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 27,488 | 70,395 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 19,634 | 48,688 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Nicholson Nur | APLS | Common Stock | D | 22,580 | 57,027 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Nicholson Nur | APLS | Common Stock | D | -1,875 | 33,680 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Lewis Karen | APLS | Common Stock | D | 19,634 | 42,075 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Lewis Karen | APLS | Common Stock | D | -1,250 | 22,224 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 22,580 | 54,230 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Chopas James George | APLS | Common Stock | D | 9,621 | 28,072 | ||||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.0800 | -12,000 | -553 | 983,780 | ||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 995,780 | ||||
| 2023-01-09 | 2023-01-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.7900 | -2,500 | -122 | 94,884 | ||||
| 2023-01-09 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-05 | 2023-01-03 | 4 | Baumal Caroline | APLS | Common Stock | D | 35,549 | 35,682 | ||||||
| 2023-01-05 | 2023-01-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 50.7000 | -500 | -25 | 132,797 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.7000 | -5,000 | -254 | 42,907 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2023-01-05 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-04 | 2023-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,867 | 267,641 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,867 | 133,297 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,867 | 13,097 | ||||||
| 2022-12-30 | 2022-12-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 7,000 | 26 | 977,280 | ||||
| 2022-12-23 | 2022-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.6800 | -89 | -5 | 31,650 | ||||
| 2022-12-23 | 2022-04-25 | 4 | Eisele Jeffrey | APLS | Common Stock | D | -1,250 | 31,739 | ||||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0697 | -24,449 | -1,273 | 965,128 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 51.9678 | -3,751 | -195 | 989,577 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 14.9500 | 6,688 | 100 | 993,328 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 15,000 | 56 | 986,640 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 28,200 | 75 | 971,640 | ||||
| 2022-12-21 | 2022-04-25 | 4 | Francois Cedric | APLS | Common Stock | D | -12,500 | 943,440 | ||||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3500 | -1,250 | -65 | 263,774 | ||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.5000 | -12,000 | -570 | 970,280 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 982,280 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.3800 | -5,000 | -252 | 42,907 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 49.9300 | -2,500 | -125 | 97,384 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9300 | -500 | -25 | 129,430 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 48.0100 | -1,250 | -60 | 263,774 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.4700 | -12,000 | -558 | 963,780 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 975,780 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5400 | -5,000 | -293 | 42,907 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.8300 | -2,500 | -152 | 99,884 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 60.8300 | -500 | -30 | 129,930 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 58.4100 | -130 | -8 | 24,844 | ||||
| 2022-10-24 | 2022-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.0000 | -196 | -11 | 29,054 | ||||
| 2022-10-24 | 2022-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 58.0000 | -130 | -8 | 18,451 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 59.3100 | -1,250 | -74 | 263,774 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 57.5000 | -12,000 | -690 | 957,280 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 969,280 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Grossi Federico | APLS | Common Stock | D | 66.6900 | -2,500 | -167 | 102,384 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.6900 | -5,000 | -333 | 42,907 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 66.0000 | -1,250 | -82 | 263,774 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.9800 | -12,000 | -768 | 950,780 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 962,780 | ||||
| 2022-09-08 | 2022-09-08 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.0000 | -15,000 | -975 | 240,679 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.3800 | -5,000 | -302 | 42,907 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-02 | 2022-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.3000 | -2,500 | -151 | 104,884 | ||||
| 2022-08-31 | 2022-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 58.8400 | -558 | -33 | 18,581 | ||||
| 2022-08-26 | 2022-08-25 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,306 | 57 | 130,430 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 69.5000 | -5,000 | -348 | 29,250 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-17 | 2022-08-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 25,394 | 356 | 126,124 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 69.0000 | -12,500 | -862 | 42,907 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 67.2100 | -1,250 | -84 | 263,774 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.6300 | -30,000 | -1,969 | 255,679 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.0000 | -5,000 | -335 | 29,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.0000 | -12,500 | -838 | 42,907 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.5000 | -12,000 | -750 | 944,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 956,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 65.0000 | -12,500 | -812 | 42,907 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.5000 | -5,000 | -322 | 29,250 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.0000 | -5,000 | -310 | 29,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 59.5000 | -5,000 | -298 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 10,000 | 155 | 39,250 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 42,907 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 56.4300 | -5,000 | -282 | 37,907 | ||||
| 2022-08-02 | 2022-08-01 | 4 | Grossi Federico | APLS | Common Stock | D | 55.9900 | -2,500 | -140 | 107,384 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 57.0000 | -5,000 | -285 | 29,250 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-22 | 2022-07-21 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 9,606 | 134 | 100,730 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.4200 | -5,000 | -282 | 29,250 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.3300 | -1,250 | -58 | 263,774 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 48.4200 | -5,000 | -242 | 42,907 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-07-12 | 2022-04-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | -1,875 | 42,138 | ||||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.9500 | -12,000 | -575 | 937,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 949,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 943,280 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Dunlop A. Sinclair Indirect Owner (ECM) | APLS | Common Stock | I | 46.7881 | -1,341 | -63 | 1,341 | ||||
| 2022-06-24 | 2022-06-23 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 45.0000 | -15,000 | -675 | 285,679 | ||||
| 2022-06-23 | 2022-06-22 | 4 | Watson David O. | APLS | Common Stock | D | 44.5140 | -10,000 | -445 | 115,569 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 33,005 | 88 | 931,280 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Brown Victoria L. | APLS | Common Stock | D | 45.0000 | -2,698 | -121 | 24,974 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 41.7850 | -10,000 | -418 | 29,250 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 39,250 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.2900 | -1,250 | -49 | 263,774 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 898,275 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0900 | -12,000 | -529 | 891,775 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 903,775 | ||||
| 2022-06-02 | 2022-06-01 | 4 | Grossi Federico | APLS | Common Stock | D | 41.7800 | -2,500 | -104 | 109,561 | ||||
| 2022-05-31 | 2022-05-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0000 | -10,000 | -430 | 40,358 | ||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | -1,875 | 50,358 | ||||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 122,279 | |||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.1800 | -1,250 | -49 | 263,774 | ||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-05-03 | 2022-05-02 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5600 | -2,500 | -109 | 112,061 | ||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Common Stock | D | -1,875 | 114,561 | ||||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,000 | 364,999 | |||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.4300 | -4,000 | -178 | 891,775 | ||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,000 | 11 | 895,775 | ||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -1,875 | 891,775 | ||||||
| 2022-04-27 | 2022-04-25 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -5,000 | -250 | 125,569 | ||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -1,875 | 130,569 | ||||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -20,000 | 35,000 | |||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 20,000 | 280 | 91,124 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -7,000 | 35,000 | |||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.5300 | -7,000 | -368 | 28,481 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 7,000 | 109 | 35,481 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 123,529 | |||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 50.9000 | -1,250 | -64 | 263,774 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -609 | 49,391 | |||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0870 | -609 | -37 | 52,233 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 609 | 8 | 52,842 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -3,504 | 50,000 | |||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 57.8050 | -1,249 | -72 | 52,233 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 56.8640 | -1,437 | -82 | 53,482 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.8400 | -818 | -46 | 54,919 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 3,504 | 49 | 55,737 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -11,496 | 53,504 | |||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.0500 | -11,496 | -633 | 52,233 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 11,496 | 159 | 63,729 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 49.2800 | -82 | -4 | 28,325 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 2.67 | -1,250 | 124,779 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.5700 | -1,250 | -49 | 259,544 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 260,794 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -7,000 | 50,723 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 39.5700 | -375 | -15 | 116,436 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 7,000 | 30 | 116,811 | ||||
| 2022-03-02 | 2022-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5300 | -375 | -16 | 109,811 | ||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -4,100 | 57,723 | |||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 4,100 | 18 | 110,186 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Grossi Federico | APLS | Common Stock | D | 45.4300 | -375 | -17 | 106,086 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 126,029 | |||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.4300 | -1,250 | -57 | 673,774 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,600 | 61,823 | |||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,600 | 16 | 106,461 | ||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -720 | 133,777 | |||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 720 | 19 | 52,233 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.1200 | -491 | -23 | 132,444 | ||||
| 2022-02-14 | 2022-02-11 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 46.8000 | -1,666 | -78 | 51,513 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.1200 | -2,523 | -119 | 955,940 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.1200 | -875 | -41 | 103,403 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.1200 | -1,057 | -50 | 893,650 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.1200 | -895 | -42 | 44,013 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 65,000 | |||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 50.0000 | -10,000 | -500 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.1200 | -678 | -32 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.1200 | -705 | -33 | 102,861 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.1200 | -175 | -8 | 28,407 | ||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.12 | 6,952 | 6,952 | |||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 4,901 | 28,481 | ||||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 47.1200 | -271 | -13 | 23,580 | ||||
| 2022-02-10 | 2021-12-08 | 5 | Watson David O. | APLS | Common Stock | D | -3,333 | 3,333 | ||||||
| 2022-02-10 | 2021-07-22 | 5 | Machiels Alec | APLS | Common Stock | D | -160,000 | 259,544 | ||||||
| 2022-02-10 | 2021-06-16 | 5 | Francois Cedric | APLS | Common Stock | D | -80,000 | 854,243 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 75,000 | |||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 45.0000 | -10,000 | -450 | 53,857 | ||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,857 | ||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Stock Option (right to buy) | D | 35.46 | 19,735 | 19,735 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Common Stock | D | 13,913 | 24,285 | ||||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Stock Option (right to buy) | D | 35.46 | 15,116 | 15,116 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Common Stock | D | 10,657 | 19,139 | ||||||
| 2022-02-02 | 2022-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5800 | -375 | -15 | 103,566 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 38.5900 | -434 | -17 | 28,582 | ||||
| 2022-02-01 | 2022-01-28 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 20,530 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 38.5900 | -650 | -25 | 103,941 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 32,989 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 38.5900 | -650 | -25 | 35,555 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 38.5900 | -650 | -25 | 104,278 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 38.5900 | -650 | -25 | 132,935 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 38.5900 | -800 | -31 | 44,908 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 38.5900 | -931 | -36 | 894,707 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 38.5900 | -434 | -17 | 23,474 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 38.5900 | -2,024 | -78 | 1,338,463 | ||||
| 2022-02-01 | 2022-01-31 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.4700 | -1,233 | -47 | 53,857 | ||||
| 2022-02-01 | 2022-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.5900 | -642 | -25 | 55,090 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 35.46 | 150,672 | 150,672 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 106,244 | 1,340,487 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26,051 | 55,732 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 35.46 | 43,670 | 43,670 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30,787 | 104,928 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 26,051 | 45,708 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 26,051 | 895,638 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Common Stock | D | 26,051 | 104,591 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 26,051 | 36,205 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 26,051 | 33,423 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 26,051 | 133,585 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 17,466 | 23,908 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Common Stock | D | 17,466 | 29,016 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 15,024 | 15,024 | |||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 10,592 | 20,964 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Stock Option (Right to Buy) | D | 35.46 | 9,892 | 9,892 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 6,974 | 15,456 | ||||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -3,021 | 134,497 | |||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 3,021 | 81 | 29,681 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Stock Option(Right to Buy) | D | 2.67 | -1,250 | 27,279 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 40.5600 | -1,250 | -51 | 673,774 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,400 | 65,423 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5600 | -375 | -15 | 78,540 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,400 | 15 | 78,915 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -1,500 | 68,823 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -3,661 | 0 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 1,500 | 6 | 75,515 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 3,661 | 14 | 74,015 | ||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 4,230 | 673,774 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 4,230 | 9,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 4,230 | 71,124 | ||||||
| 2022-01-04 | 2022-01-03 | 4 | Grossi Federico | APLS | Common Stock | D | 47.3100 | -375 | -18 | 70,354 | ||||
| 2021-12-28 | 2021-12-27 | 4 | Watson David O. | APLS | Common Stock | D | 48.5000 | -1,200 | -58 | 107,534 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -5,397 | 14,888 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -4,715 | 20,285 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -4,826 | 11,667 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -5,174 | 16,493 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 48.5770 | -300 | -15 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.8550 | -5,097 | -244 | 109,034 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 5,397 | 81 | 114,131 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 4,715 | 70 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.7160 | -5,174 | -247 | 104,019 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 4,826 | 67 | 109,193 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 5,174 | 72 | 104,367 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 47.8200 | -89 | -4 | 7,372 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8800 | -375 | -16 | 70,729 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 128,529 | |||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 42.8800 | -3,000 | -129 | 669,544 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -7,000 | 3,661 | |||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 7,000 | 26 | 71,104 | ||||
| 2021-12-03 | 2021-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 42.4000 | -375 | -16 | 64,104 | ||||
| 2021-11-18 | 2021-11-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 40.0000 | 250,000 | 10,000 | 12,806,342 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 131,529 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 43.5000 | -3,000 | -130 | 669,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 134,529 | |||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -3,000 | -105 | 669,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5000 | -625 | -27 | 64,479 | ||||
| 2021-11-02 | 2021-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.7000 | -625 | -19 | 64,805 | ||||
| 2021-10-27 | 2021-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 882 | 8,482 | ||||||
| 2021-10-27 | 2021-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 882 | 10,372 | ||||||
| 2021-10-27 | 2021-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 882 | 11,422 | ||||||
| 2021-10-15 | 2021-10-14 | 4 | Grossi Federico | APLS | Common Stock | D | 34.5700 | -750 | -26 | 65,430 | ||||
| 2021-10-05 | 2021-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 33.2600 | -750 | -25 | 66,180 | ||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -4,000 | 10,661 | |||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 4,000 | 15 | 66,930 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -6,894 | 55,000 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 6,894 | 97 | 66,894 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -954 | 0 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 954 | 4 | 99,193 | ||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Stock Option (right to buy) | D | 65.41 | 21,750 | 21,750 | |||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 7,600 | 7,600 | ||||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 137,529 | |||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 56.9500 | -2,500 | -142 | 669,544 | ||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Grossi Federico | APLS | Common Stock | D | 63.9900 | -250 | -16 | 62,930 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 6,161 | |||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 63.9900 | -1,000 | -64 | 4,847 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 42,000 | |||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 65.0000 | -1,000 | -65 | 9,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -14,410 | 375,538 | |||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 14,410 | 62 | 1,234,243 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 43,000 | |||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.3000 | -1,000 | -62 | 9,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 140,029 | |||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 62.3000 | -2,500 | -156 | 669,544 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-07-15 | 2021-07-14 | 4 | Grossi Federico | APLS | Common Stock | D | 64.6800 | -500 | -32 | 63,180 | ||||
| 2021-07-09 | 2021-07-08 | 4 | Grossi Federico | APLS | Common Stock | D | 65.6800 | -250 | -16 | 63,680 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 7,161 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 64.0000 | -1,000 | -64 | 4,847 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -9,000 | 14,661 | |||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 9,000 | 34 | 63,930 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 368,999 | |||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 65.6100 | -6,250 | -410 | 869,587 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 954 | |||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 98,239 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 142,529 | |||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 64.8300 | -2,500 | -162 | 669,544 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -4,000 | 44,000 | |||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9575 | -4,000 | -260 | 9,490 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 4,000 | 62 | 13,490 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.20 | -1,000 | 34,161 | |||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 61.5550 | -1,000 | -62 | 4,847 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.2000 | 1,000 | 3 | 5,847 | ||||
| 2021-06-15 | 2021-06-14 | 4 | Grossi Federico | APLS | Common Stock | D | 61.8400 | -500 | -31 | 54,930 | ||||
| 2021-06-11 | 2021-06-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -3,417 | -205 | 26,651 | ||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 10.03 | -39,880 | 358,619 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 39,880 | 400 | 74,141 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 2,682 | 303,361 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13,108 | 73,108 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | -31,855 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 8,161 | |||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 56.4000 | -1,000 | -56 | 4,847 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,443 | |||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,750 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 375,249 | |||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.4000 | -6,250 | -296 | 869,587 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-05-20 | 2021-05-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 48.1000 | -5,773 | -278 | 31,855 | ||||
| 2021-05-20 | 2021-05-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0000 | -7,612 | -381 | 300,679 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.0200 | -800 | -43 | 308,291 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.5000 | -10,388 | -556 | 309,091 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.0100 | -1,200 | -62 | 319,479 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.5700 | -22,318 | -1,218 | 37,628 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.7800 | -36,387 | -1,957 | 59,946 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.6300 | -14,216 | -748 | 96,333 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.6600 | -64,179 | -3,315 | 110,549 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -2,000 | 48,000 | |||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 55.0000 | -2,000 | -110 | 9,490 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 2,000 | 31 | 11,490 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Grossi Federico | APLS | Common Stock | D | 45.3900 | -500 | -23 | 55,430 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 145,029 | |||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3900 | -2,500 | -113 | 669,544 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 9,161 | |||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.7300 | -1,000 | -51 | 4,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Grossi Federico | APLS | Common Stock | D | 50.7300 | -600 | -30 | 55,614 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 10,161 | |||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -1,000 | -50 | 4,847 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,500 | 381,499 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,500 | 12 | 869,587 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 385,999 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.1300 | -6,250 | -288 | 865,087 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -10,000 | 61,894 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 10,000 | 140 | 60,000 | ||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,932 | |||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,261 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 147,529 | |||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 45.7600 | -2,500 | -114 | 669,544 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -50,000 | 71,894 | |||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 50,000 | 700 | 50,000 | ||||
| 2021-04-15 | 2021-04-14 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8200 | -500 | -21 | 56,214 | ||||
| 2021-04-09 | 3 | DeLong Mark Jeffrey | APLS | Common Stock | D | 8,698 | ||||||||
| 2021-04-05 | 2021-04-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.4100 | -600 | -26 | 56,714 | ||||
| 2021-03-29 | 2021-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 41.1600 | -82 | -3 | 9,952 | ||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -978 | 2,421 | |||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 978 | 4 | 96,772 | ||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Common Stock | D | 1,250 | 10,034 | ||||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 150,029 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.7700 | -2,500 | -117 | 669,544 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 46.7700 | -500 | -23 | 57,314 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 392,249 | |||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 50.7400 | -6,250 | -317 | 865,087 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,000 | 34,073 | |||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.6150 | -5,000 | -243 | 57,814 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,000 | 16 | 62,814 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,250 | 7,461 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 11,161 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.5800 | -600 | -29 | 57,814 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Grossi Federico | APLS | Common Stock | D | 46.0000 | -500 | -23 | 58,414 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 152,529 | |||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 46.0000 | -2,500 | -115 | 669,544 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-02-11 | 2021-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.7200 | -680 | -32 | 29,290 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.7200 | -858 | -41 | 34,261 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 47.7200 | -153 | -7 | 2,347 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.7200 | -688 | -33 | 865,087 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.7200 | -688 | -33 | 18,865 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.7200 | -144 | -7 | 8,784 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.7200 | -688 | -33 | 58,914 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.7200 | -2,523 | -120 | 1,219,833 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.7200 | -468 | -22 | 95,794 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 13,161 | |||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,500 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,500 | ||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | I | 250,000 | 250,000 | ||||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | D | -250,000 | 419,544 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | I | 300,000 | 300,000 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | D | -300,000 | 813,079 | ||||||
| 2021-02-02 | 2021-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 44.0000 | -600 | -26 | 59,602 | ||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 1,875 | 19,553 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 7,500 | 17,678 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 1,875 | 60,202 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 7,500 | 58,327 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 22,500 | 22,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 3,750 | 35,119 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 7,500 | 31,369 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 75,000 | 75,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 150,000 | 150,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 12,500 | 1,222,356 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 25,000 | 1,209,856 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 1,875 | 96,262 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 7,500 | 94,387 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 1,875 | 29,970 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 7,500 | 28,095 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 1,875 | 9,375 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 7,500 | 7,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 7,500 | 7,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 1,250 | 6,250 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 5,000 | 5,000 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 5,000 | 8,928 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 5,000 | 6,211 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 44.90 | 15,000 | 15,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 1,875 | 865,775 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 7,500 | 863,900 | ||||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -31,992 | 389,948 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -39,785 | 273,840 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 31,992 | 138 | 1,184,856 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 39,785 | 150 | 1,152,864 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -20,042 | 3,399 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 3.76 | -23,441 | 0 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 20,042 | 86 | 86,887 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 3.7600 | 23,441 | 88 | 66,845 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -11,500 | 23,661 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -3,500 | 39,073 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 11,500 | 43 | 50,827 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 3,500 | 11 | 39,327 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 155,029 | |||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 53.1500 | -2,500 | -133 | 669,544 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-01-15 | 2021-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 51.9900 | -4,000 | -208 | 35,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Grossi Federico | APLS | Common Stock | D | 57.2400 | -600 | -34 | 39,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 15,161 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 57.2400 | -2,000 | -114 | 0 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 2,000 | ||||
| 2021-01-04 | 2021-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2020-12-23 | 2020-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,211 | 1,211 | ||||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 157,529 | |||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.1600 | -2,500 | -130 | 669,544 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Francois Cedric | APLS | Common Stock | D | 52.1600 | -5,000 | -261 | 1,113,079 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 56.2500 | -214 | -12 | 174,728 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 55.0100 | -17,132 | -942 | 174,942 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.8600 | -7,654 | -412 | 192,074 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -8,398 | 21,667 | |||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.9080 | -200 | -11 | 43,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.0010 | -900 | -50 | 43,604 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 53.8610 | -900 | -48 | 44,504 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 52.7270 | -1,163 | -61 | 45,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 51.3160 | -2,526 | -130 | 46,567 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 50.6070 | -2,709 | -137 | 49,093 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 8,398 | 116 | 51,802 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -9,935 | 30,065 | |||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -9,935 | -497 | 43,404 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 9,935 | 138 | 53,339 | ||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -7,482 | 137,518 | |||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 7,482 | 200 | 20,595 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -18,000 | 17,161 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -18,000 | -900 | 0 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 18,000 | 68 | 18,000 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -7,250 | 42,573 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 7,250 | 23 | 40,427 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0000 | -9,470 | -483 | 199,728 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.4100 | -9,094 | -458 | 209,198 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0500 | -1,384 | -71 | 218,292 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0400 | -5,052 | -253 | 219,676 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -40,000 | 313,625 | |||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 40,000 | 150 | 1,118,079 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.2500 | -600 | -29 | 33,177 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Francois Cedric | APLS | Common Stock | D | 39.3800 | -5,000 | -197 | 1,078,079 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,750 | 49,823 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,750 | 18 | 33,777 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 160,029 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.3800 | -2,500 | -98 | 669,544 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-11-03 | 2020-11-02 | 4 | Grossi Federico | APLS | Common Stock | D | 31.0900 | -600 | -19 | 27,725 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 162,529 | |||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -2,500 | -88 | 669,544 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 34.4600 | -5,000 | -172 | 1,083,079 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -7,500 | 165,029 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -7,500 | -262 | 669,544 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 7,500 | 20 | 677,044 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 18.98 | -12,000 | 39,268 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 35.0000 | -12,000 | -420 | 3,607 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 18.9800 | 12,000 | 228 | 15,607 | ||||
| 2020-10-02 | 2020-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2200 | -600 | -18 | 28,325 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.9600 | -5,000 | -155 | 1,088,079 | ||||
| 2020-09-02 | 2020-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 31.5800 | -600 | -19 | 28,925 | ||||
| 2020-08-21 | 2020-08-20 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -3,457 | -104 | 1,093,079 | ||||
| 2020-08-20 | 2020-08-18 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -1,543 | -46 | 1,096,536 | ||||
| 2020-08-05 | 2020-08-03 | 4 | Grossi Federico | APLS | Common Stock | D | 26.2800 | -600 | -16 | 29,525 | ||||
| 2020-07-16 | 2020-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 32.1200 | -5,000 | -161 | 1,098,079 | ||||
| 2020-07-02 | 2020-07-01 | 4 | Grossi Federico | APLS | Common Stock | D | 32.4300 | -850 | -28 | 30,125 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 172,529 | |||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.2100 | -2,500 | -76 | 669,544 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2100 | -856 | -26 | 30,975 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.2100 | -5,000 | -151 | 1,103,079 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 175,029 | |||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9200 | -5,000 | -150 | 1,108,079 | ||||
| 2020-05-12 | 2020-05-08 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 31.8068 | 5,000 | 159 | 5,000 | ||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 177,529 | |||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.7700 | -5,000 | -149 | 1,113,079 | ||||
| 2020-04-06 | 2020-04-02 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 26.13 | 37,500 | 37,500 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 180,029 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 0 | |||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 30,637 | |||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 23.8600 | -300 | -7 | 1,053,067 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2780 | -3,212 | -72 | 1,053,367 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5790 | -15,065 | -325 | 1,056,579 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.6930 | -12,060 | -250 | 1,071,644 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2860 | -700 | -16 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5690 | -2,192 | -47 | 1,084,404 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.7280 | -2,108 | -44 | 1,086,596 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,088,704 | ||||
| 2020-03-12 | 2020-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -161,656 | 847,025 | ||||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 61,274 | |||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,058,067 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 91,911 | |||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6660 | -5,000 | -203 | 1,027,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6630 | -30,637 | -1,246 | 1,032,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,063,067 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 182,529 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 42.3500 | -2,500 | -106 | 669,544 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,205 | 0 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.9790 | -55,398 | -2,270 | 1,008,681 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,205 | 251 | 1,064,079 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,206 | 117,205 | |||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8030 | -52,075 | -2,229 | 946,874 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,206 | 251 | 998,949 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 2.67 | -7,505 | 0 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 44.33 | 38,250 | 38,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 7,505 | 20 | 42,922 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 44.5000 | -5,000 | -222 | 35,417 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 6,375 | 40,417 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 9,375 | 31,831 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Common Stock | D | 2,725 | 2,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Common Stock | D | 2,725 | 7,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 44.33 | 15,000 | 15,000 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Stock option (right to buy) | D | 44.33 | 31,275 | 31,275 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Common Stock | D | 5,213 | 5,213 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,375 | 9,375 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 44.33 | 206,250 | 206,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 34,375 | 1,066,805 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 44.33 | 70,125 | 70,125 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,688 | 23,387 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,375 | 891,118 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,375 | 12,310 | ||||||
| 2020-02-05 | 3/A | Machiels Alec | APLS | Common Stock | I | 1,020 | ||||||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -15,000 | 7,505 | |||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 15,000 | 40 | 34,042 | ||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 40.4670 | -3,000 | -121 | 19,042 | ||||
| 2020-01-21 | 2020-01-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 37.0000 | 540,540 | 20,000 | 12,556,342 | ||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 122,548 | |||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,032,430 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,638 | 153,185 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,638 | 66 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 41.4700 | -5,000 | -207 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.5470 | -4,562 | -194 | 1,006,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.1590 | -26,076 | -1,099 | 1,011,355 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 185,029 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 41.4700 | -2,500 | -104 | 669,544 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-01-03 | 2020-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2019-12-20 | 2019-12-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5300 | -25,000 | -738 | 224,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5100 | -31,000 | -915 | 249,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.9900 | -54,110 | -1,569 | 320,681 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.5500 | -25,890 | -739 | 374,791 | ||||
| 2019-12-17 | 2019-12-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.9500 | -5,000 | -140 | 1,006,793 | ||||
| 2019-11-18 | 2019-11-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.2810 | -5,000 | -136 | 1,011,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.6130 | -3,524 | -94 | 1,016,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 25.5870 | -1,476 | -38 | 1,020,317 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.6410 | -1,010 | -26 | 881,743 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.2380 | -20,531 | -518 | 882,753 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.9580 | -1,295 | -32 | 903,284 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.5610 | -20,307 | -499 | 904,579 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.5300 | -100 | -3 | 924,886 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.0680 | -20,758 | -520 | 924,986 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.1700 | -260 | -7 | 1,021,793 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 26.5580 | -4,740 | -126 | 1,022,053 | ||||
| 2019-09-03 | 2019-08-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.7145 | 11,699 | 348 | 11,699 | ||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.67 | -37,505 | 478,200 | |||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 37,505 | 100 | 1,026,793 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -10,000 | 183,823 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.0000 | -2,246 | -61 | 989,288 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.7430 | -7,754 | -207 | 991,534 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 10,000 | 21 | 999,288 | ||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -5,000 | 22,505 | |||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 5,000 | 13 | 22,042 | ||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -275,000 | 193,823 | |||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 275,000 | 588 | 989,288 | ||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-03-13 | 2019-03-11 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 17.0000 | 441,176 | 7,500 | 12,015,802 | ||||
| 2019-02-12 | 2019-02-08 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 13.85 | 40,000 | 40,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 13.85 | 22,000 | 22,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 13.85 | 281,000 | 281,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Chan Gerald | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Stock Option (Right to Buy) | D | 2.59 | -11,500 | 348,389 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 11,500 | 30 | 50,110 | ||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -6,250 | 55,573 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 6,250 | 20 | 22,456 | ||||
| 2018-09-24 | 2018-09-21 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.8400 | 40,000 | 794 | 11,574,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.4300 | 21,724 | 422 | 11,534,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.7900 | 19,599 | 368 | 11,512,902 | ||||
| 2018-09-19 | 2018-09-19 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.0900 | 60,000 | 1,085 | 11,493,303 | ||||
| 2018-09-19 | 2018-09-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.4700 | 40,000 | 739 | 11,433,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.8400 | 8,600 | 162 | 11,393,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.5000 | 31,400 | 581 | 11,384,703 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -32,818 | 27,505 | |||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 18.7840 | -15,776 | -296 | 17,042 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 32,818 | 88 | 32,818 | ||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -624 | 60,323 | |||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | -624 | 0 | ||||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 624 | 2 | 624 | ||||
| 2018-05-29 | 2018-05-24 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 20.3700 | 2,935 | 60 | 2,935 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 384,292 | 945,744 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 94,357 | 280,728 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Francois Cedric | APLS | Common Stock | D | 384,292 | 714,288 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Grossi Federico | APLS | Common Stock | D | 7,706 | 16,206 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec Held by spouse | APLS | Common Stock | I | 930 | 930 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec | APLS | Common Stock | D | 288,219 | 669,544 | ||||||
| 2018-04-17 | 3 | SCHEIBLER LUKAS | APLS | No securities are beneficially owned | D | 0 | ||||||||
| 2018-04-17 | 2018-04-13 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (right to buy) | D | 26.73 | 145,000 | 145,000 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 3.20 | -8,500 | 61,823 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 8,500 | 27 | 8,500 | ||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 2.59 | 38,610 | 359,889 | |||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 38,610 | 100 | 38,610 | ||||
| 2018-02-21 | 2018-02-16 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 14.95 | 60,000 | 60,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Francois Cedric | APLS | Stock Option (right to buy) | D | 14.95 | 280,000 | 280,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 14.95 | 200,000 | 200,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Perry Nicole D | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Deschatelets Pascal | APLS | Stock Option (right to buy) | D | 14.95 | 110,000 | 110,000 | |||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Series D Convertible Preferred Stock | I | 4,476,275 | 0 | ||||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 14.0000 | 1,428,571 | 20,000 | 3,527,152 | ||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 2,098,581 | 2,098,581 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series E Convertible Preferred Stock | D | -303,916 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series D Convertible Preferred Stock | D | -2,098,581 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 14.0000 | 1,071,428 | 15,000 | 3,473,925 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 2,402,497 | 2,402,497 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series C Preferred Stock | D | -556,830 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series B Preferred Stock | D | -545,454 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series A Preferred Stock | D | -600,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Common Stock | D | 798,068 | 943,989 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series E Preferred Stock | D | -259,302 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series D Preferred Stock | D | -4,476,275 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series C Preferred Stock | D | -17,200,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series B Preferred Stock | D | -1,054,544 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 14.0000 | 575,000 | 8,050 | 11,353,303 | ||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 10,778,303 | 10,778,303 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series E Preferred Stock | D | -648,256 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series D Preferred Stock | D | -6,714,413 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 14.0000 | 127,515 | 1,785 | 3,579,305 | ||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 3,451,790 | 3,451,790 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series D Preferred Stock | I | -888,969 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series C Preferred Stock | I | -4,000,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Common Stock | I | 2,292,062 | 2,292,062 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series E Preferred Stock | I | -6,078 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series D Preferred Stock | I | -31,478 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series C Preferred Stock | I | -150,023 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series B Preferred Stock | I | -213,100 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 400,679 | 400,679 | ||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 |
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)
