CLNN Stock Financial Analysis - Clene Inc. (NasdaqCM) Stock

Overview

Clene Inc. is a biopharmaceutical company based in the United States, primarily focused on the innovation of unique therapies for neurodegenerative diseases. The company is pioneering in the development of nanotherapeutics designed to enhance cellular energetics. One of their key projects includes CNM-Au8, an investigational nanocatalyst aimed at improving the cellular bioenergetic processes critical for repairing and maintaining cellular health. The company’s approach involves a proprietary clean-surfaced nanotechnology platform that is being tested in various clinical trials for conditions such as multiple sclerosis, Parkinson’s disease, and amyotrophic lateral sclerosis. With its uniquely positioned technology, Clene Inc. is committed to addressing complex neurodegenerative disorders by improving fundamental cellular functions.

Quality, Value, Momentum Scores

This card shows the Quality, Value, and Momentum scores for the company

Quality

The QualityScore is a proprietary scoring model that identifies high quality companies, based on cash generating efficiencies.

Value

Proprietary scoring model that ranks companies based on their relative valuation. Scores range from 0 to 100, with 100 being the most undervalued.

Momentum

Proprietary scoring model that ranks companies on their six-month momentum.

Fund Sentiment

The Fund Sentiment (fka Ownership) score is a proprietary quantitative model that ranks companies based on levels of ownership accumulation.

QVM

The QVM Score is a proprietary scoring model that combines Quality, Value, and Momentum into a single metric that ranks companies from 0 to 100.

Income Statement: Revenue, Operating Income, Net Income

The revenue for Clene Inc. as of June 30, 2025 is 0.29 MM.
The operating income for Clene Inc. as of June 30, 2025 is -26.41 MM.
The net income for Clene Inc. as of June 30, 2025 is -29.70 MM.

Period End (TTM)	Revenue (MM)	Operating Income (MM)	Net Income (MM)
2025-06-30	0.29	-26.41	-29.70
2025-03-31	0.35	-27.94	-29.07
2024-12-31	0.34	-33.09	-39.40
2024-09-30	0.42	-34.37	-36.02
2024-06-30	0.44	-36.09	-30.46
2024-03-31	0.62	-39.04	-48.81
2023-12-31	0.65	-40.54	-49.50
2023-09-30	0.72	-42.28	-40.38
2023-06-30	0.78	-42.55	-48.94
2023-03-31	0.55	-45.80	-28.33
2022-12-31	0.47	-48.41	-29.92
2022-09-30	0.44	-50.79	-24.44
2022-06-30	0.37	-51.44	15.48
2022-03-31	0.54	-51.62	16.66
2021-12-31	0.72	-49.98	-9.74
2021-09-30	0.55	-41.88	-13.38
2021-06-30	0.54	-37.12	-52.62
2021-03-31	0.35	-27.91	-55.09
2020-12-31	0.21	-20.21	-19.28
2020-09-30	0.18	-18.61	-24.30

Income Statement: EPS

The earnings per share basic for Clene Inc. as of June 30, 2025 is -3.57.
The earnings per share diluted for Clene Inc. as of June 30, 2025 is -3.57.

Period End (TTM)	Earnings Per Share Basic	Earnings Per Share Diluted
2025-06-30	-3.57	-3.57
2025-03-31	-3.85	-3.85
2024-12-31	-5.67
2024-09-30	-5.58	-5.58
2024-06-30	-4.74	-4.74
2024-03-31	-8.27	-8.27
2023-12-31	-9.43
2023-09-30	-8.92	-8.92
2023-06-30	-13.19	-13.19
2023-03-31	-0.41	-0.41
2022-12-31	-0.46
2022-09-30	-0.39	-0.39
2022-06-30	0.25	0.25
2022-03-31	0.27	0.27
2021-12-31	-0.16
2021-09-30	-0.27	-0.26
2021-06-30	-1.34	-1.34
2021-03-31	-1.94	-1.94
2020-12-31	-1.10
2020-09-30	-0.19	-0.20

Cash Flow: Operations, Investing, Financing

The cash from operating activities for Clene Inc. as of June 30, 2025 is -17.64 MM.
The cash from investing activities for Clene Inc. as of June 30, 2025 is -0.00 MM.
The cash from financing activities for Clene Inc. as of June 30, 2025 is 3.27 MM.

Period End (TTM)	Cash From Operating Activities (MM)	Cash From Investing Activities (MM)	Cash From Financing Activities (MM)
2025-06-30	-17.64	-0.00	3.27
2025-03-31	-19.25	6.25	1.16
2024-12-31	-21.33	6.32	-1.53
2024-09-30	-23.63	0.11	-4.08
2024-06-30	-27.37	0.06	-0.25
2024-03-31	-28.04	-6.15	37.56
2023-12-31	-30.17	-1.50	42.16
2023-09-30	-30.71	7.00	58.55
2023-06-30	-32.44	15.45	58.88
2023-03-31	-35.15	19.08	21.60
2022-12-31	-39.01	-10.16	17.25
2022-09-30	-40.90	-13.12	0.86
2022-06-30	-39.73	-21.77	6.00
2022-03-31	-38.55	-25.65	29.24
2021-12-31	-34.62	-1.33	27.11
2021-09-30	-30.83	-0.78	55.30
2021-06-30	-31.24	-0.61	87.76
2021-03-31	-24.84	-0.57	66.09
2020-12-31	-18.93	-0.39	69.53
2020-09-30	-16.48	-0.31	41.32

Valuation Metrics : PE, PriceToBook, PriceToTBV

The p/book for Clene Inc. as of June 30, 2025 is -6.99.
The p/tbv for Clene Inc. as of June 30, 2025 is -6.99.

P/Book: The current closing price divided by the book value per share.

P/TBV: The current price divided by the tangible book value per share.

Period End (TTM)	p/e	P/Book	P/TBV
2025-06-30		-6.99	-6.99
2025-03-31	-0.70	-3.12	-3.12
2024-12-31		-9.67	-9.67
2024-09-30	-1.02	-61.88	-61.88
2024-06-30	-0.97	11.11	11.11
2024-03-31		4.08	4.08
2023-12-31	-0.92	1.74	1.74
2023-09-30	-1.26	2.87	2.87
2023-06-30	-2.43	-42.40	-42.40
2023-03-31	-2.93	27.05
2022-12-31		-7.92	-7.92
2022-09-30		-315.82	-315.82
2022-06-30	9.55	78.87	78.87
2022-03-31	-25.37	19.62	19.62
2021-12-31	-19.05	44.85	44.85
2021-09-30	-8.00	-16.25	-16.25
2021-06-30
2021-03-31	-3.40	-5.19	-5.19
2020-12-31	-9.71	549.00	549.00
2020-09-30

Valuation Metrics : EBitToEv, EBit3YrAvgToEv

The ebit/ev for Clene Inc. as of June 30, 2025 is -0.71.
The ebit (3y)/ev for Clene Inc. as of June 30, 2025 is -0.88.

Period End (TTM)	EBIT/EV	EBIT (3y)/EV
2025-06-30	-0.71	-0.88
2025-03-31	-1.26	-1.24
2024-12-31	-0.84	-0.89
2024-09-30	-0.82	-0.86
2024-06-30	-0.92	-0.38
2024-03-31	-0.94	-0.57
2023-12-31	-1.89	-1.22
2023-09-30	-1.27	-0.75
2023-06-30	-0.37	-0.28
2023-03-31	-0.32	-0.24
2022-12-31	-0.28	-0.24
2022-09-30	0.08	-0.04
2022-06-30	0.10	-0.11
2022-03-31	-0.05	-0.13
2021-12-31	-0.06	-0.08
2021-09-30	-0.14	-0.07
2021-06-30
2021-03-31	-0.21	-0.10
2020-12-31	-0.07	-0.06
2020-09-30

Management Effectiveness

The roa for Clene Inc. as of June 30, 2025 is -0.72.
The roic for Clene Inc. as of June 30, 2025 is -1.82.
The croic for Clene Inc. as of June 30, 2025 is -0.75.
The ocroic for Clene Inc. as of June 30, 2025 is -1.21.

Period End (TTM)	ROA	ROE	ROIC	CROIC	OCROIC
2025-06-30	-0.72		-1.82	-0.75	-1.21
2025-03-31	-0.87	-9.24	-3.29	-1.39	-1.78
2024-12-31	-0.69	-2.69	-1.92	-1.46	-1.26
2024-09-30	-0.50	-1.42	-0.95	-0.86	-0.85
2024-06-30	-1.22		-1.33	0.09	-0.76
2024-03-31	-1.11	-15.29	-1.09	0.23	-0.66
2023-12-31	-1.12		-0.76	0.65	-0.58
2023-09-30	-1.10		-0.92	0.79	-0.61
2023-06-30	-0.64		-0.91	0.78	-0.60
2023-03-31	-0.56	-14.83	-0.94	0.18	-1.17
2022-12-31	-0.33	-4.30	-1.40	-3.05	-2.34
2022-09-30	0.21	2.72	-1.42	-3.09	-2.37
2022-06-30	0.23		0.61	-2.20	-1.57
2022-03-31	-0.17		0.60	-1.27	-1.40
2021-12-31	-0.20	-39.25	-0.27	-0.24	-1.05
2021-09-30	-0.28	-1.39	-0.53
2021-06-30	-3.99	-52.21
2021-03-31	-3.70	-6.80
2020-12-31	-1.30	-2.38	-2.55	6.68	-2.50
2020-09-30		-1.58	-0.54	0.55	-0.37

Gross Margins

The gross margin for Clene Inc. as of June 30, 2025 is 0.79.
The net margin for Clene Inc. as of June 30, 2025 is -83.06.
The operating margin for Clene Inc. as of June 30, 2025 is -79.82.

Gross Margin: The Gross Margin is the ratio of revenue left after substracting the Cost of Goods Sold. It is calculated as 1.0 - (Revenue - COGS ) / Revenue.

Net Margin: The Net Margin (aka Profit Margin) is the ratio of revenue left after substracting the Net Income. It is calculated as Net Income / Revenue.

Operating Margin: The Operaing Margin is the ratio of revenue left after substracting the Operating Income. It is calculated as Operating Income / Revenue.

Period End (TTM)	Gross Margin	Net Margin	Operating Margin
2025-06-30	0.79	-83.06	-79.82
2025-03-31	0.80	-115.20	-96.76
2024-12-31	0.79	-85.57	-81.63
2024-09-30	0.81	-68.90	-81.66
2024-06-30	0.79	-78.73	-62.97
2024-03-31	0.81	-75.69	-61.99
2023-12-31	0.87	-56.25	-58.89
2023-09-30	0.88	-62.43	-54.27
2023-06-30	0.94	-62.43	-54.27
2023-03-31	0.95	-51.52	-83.28
2022-12-31	2.15	-55.80	-115.97
2022-09-30	2.36	-55.80	-115.97
2022-06-30	0.91	41.39	-137.54
2022-03-31	0.60	30.86	-95.59
2021-12-31	-0.48	-13.47	-69.13
2021-09-30	-0.49	-24.20	-75.73
2021-06-30	-0.49	-97.27	-68.62
2021-03-31	0.28	-157.86	-79.96
2020-12-31	0.68	-93.58	-98.13
2020-09-30	0.67	-137.27	-105.13