STE / STERIS plc - SEC Filings, Annual Report, Proxy Statement

STERIS plc
US ˙ NYSE

Basic Stats
LEI 549300BRDKZ1HFI2J358
CIK 1757898
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to STERIS plc
SEC Filings (Chronological Order)
This page provides a complete, chronological list of SEC Filings, excluding ownership filings which we provide elsewhere.
August 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

August 7, 2025 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated August 7, 2025 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for the

August 6, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 STERIS plc (Exact N

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2025 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fil

August 6, 2025 EX-99.1

STERIS Announces Financial Results for Fiscal 2026 First Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2026 First Quarter • Total revenue from continuing operations increased 9%; constant currency organic revenue grew 8% • As reported EPS from continuing operations increased to $1.79; adjusted EPS increased to $2.34 • Fiscal 2026 outlook updated DUBLIN, IRELAND - (August 6, 2025) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today an

August 6, 2025 EX-99.2

STERIS Announces Chief Financial Officer Transition Long-time CFO Michael J. Tokich to be succeeded by Karen L. Burton, Chief Accounting Officer

Exhibit 99.2 STERIS Announces Chief Financial Officer Transition Long-time CFO Michael J. Tokich to be succeeded by Karen L. Burton, Chief Accounting Officer DUBLIN, IRELAND – August 6, 2025 - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) announced today that Michael J. Tokich, Senior Vice President and Chief Financial Officer (CFO), is stepping down from his role following seventeen years as

July 3, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A PROXY STATEMENT Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.  ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only as permitted by Rule 14a-6(e)(2))

July 3, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 1, 2025 STERIS plc (Exact Na

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 1, 2025 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

June 25, 2025 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K ý Annual Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the Twelve Month Period Ended December 31, 2024 OR o Transition Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the transition period from to Commission file number 001-38848 A. Full title of the plan and the address o

June 12, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only as permitted by Rule 14a-6(e)(2))

June 12, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant  ☒ Filed by a party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only   (as permitted by Rul

May 30, 2025 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation

SD UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 70 Sir John Rogerson’s Quay, Dublin 2, Ireland DE21 6LY (Address of principal executiv

May 30, 2025 EX-1.01

Conflict Minerals Report as required by Items 1.01 and 1.02 of this Form SD.

Exhibit 1.01 STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2024, to December 31, 2024 Introduction This Conflict Minerals Report is filed by STERIS plc (“STERIS”) for the reporting period from January 1, 2024 to December 31, 2024 (the “Reporting Period”) as Exhibit 1.01 to STERIS’s Form SD pursuant to the requirements of Rule 13p-1 of the Securities Exchange Act of 1

May 29, 2025 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-38848 STERIS plc (Exact name of registrant as specified i

May 29, 2025 EX-24.1

Power of Attorney

Exhibit 24.1 STERIS PLC POWER OF ATTORNEY FORM 10-K Each of the undersigned hereby makes, constitutes, and appoints Daniel A. Carestio, Michael J. Tokich, Karen L. Burton, and J. Adam Zangerle, and each of them, his or her true and lawful attorney, with full power of substitution, for and in his or her name, place, and stead, to affix, as attorney-in-fact, his or her signature in any and all capac

May 29, 2025 EX-21.1

Subsidiaries of STERIS plc.

Exhibit 21.1 SUBSIDIARIES OF STERIS PLC STERIS plc has no parent company. As of March 31, 2025, its direct and indirect subsidiaries were as follows: Name Jurisdiction of Incorporation Albert Browne Limited England and Wales American Sterilizer Company Pennsylvania, USA Bioster-Mottahedoon Egypt SAE Egypt Birkova Products, LLC Indiana, USA Bizworth Gammarad Sdn Bhd Malaysia Black Diamond Video, In

May 14, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 14, 2025 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

May 14, 2025 EX-99.1

STERIS Announces Financial Results for Fiscal 2025 Fourth Quarter and Full Year

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2025 Fourth Quarter and Full Year • Full year fiscal 2025 revenue from continuing operations increased 6%; constant currency organic revenue growth was 6% • Full year fiscal 2025 as reported diluted EPS from continuing operations increased to $6.16; adjusted EPS per diluted share increased to $9.22 • Fiscal 2026 outlook provided DUBLIN, IR

March 3, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2025 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fil

February 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended December 31, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

February 7, 2025 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated February 7, 2025 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

February 5, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 5, 2025 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

February 5, 2025 EX-99.1

STERIS Announces Financial Results for Fiscal 2025 Third Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2025 Third Quarter • Total revenue from continuing operations increased 6%; constant currency organic revenue grew 6% • As reported EPS from continuing operations increased to $1.75; adjusted EPS increased to $2.32 • Fiscal 2025 outlook updated DUBLIN, IRELAND - (February 5, 2025) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today

November 7, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numb

November 7, 2024 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated November 7, 2024 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

November 7, 2024 EX-10.1

Description of STERIS plc Non-Employee Director Compensation Program.*

Exhibit 10.1 Description of STERIS plc Non-Employee Director Compensation Program Summarized below is the Director compensation program for STERIS plc (“STERIS”) non-employee Directors for the term of office beginning August 1, 2024. Director retainer fees have remained the same for the 2024-2025 term of office as for the prior term of office. An annual retainer of $323,000 is payable to each non-

November 6, 2024 EX-99.1

STERIS Announces Financial Results for Fiscal 2025 Second Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2025 Second Quarter • Total revenue from continuing operations increased 7%; constant currency organic revenue grew 7% • As reported EPS from continuing operations increased to $1.51; adjusted EPS increased to $2.14 • Fiscal 2025 outlook reiterated DUBLIN, IRELAND - (November 6, 2024) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) to

November 6, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 6, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

October 7, 2024 8-K

Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 7, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

October 7, 2024 EX-10.1

Credit Agreement, dated as of October 7, 2024, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent. †

Exhibit 10.1 $1,100,000,000 CREDIT AGREEMENT Dated as of October 7, 2024 among STERIS PLC, as a Borrower, STERIS LIMITED, as a Borrower, STERIS CORPORATION, as a Borrower, STERIS IRISH FINCO UNLIMITED COMPANY, as a Borrower, The Guarantors Party Hereto, VARIOUS FINANCIAL INSTITUTIONS, as Lenders, and JPMORGAN CHASE BANK, N.A., as Administrative Agent BOFA SECURITIES, INC., CITIBANK, N.A. PNC BANK,

August 8, 2024 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated August 8, 2024 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for the

August 8, 2024 EX-2.1

Equity Purchase Agreement by and between STERIS Corporation, HuFriedy Group Holding LLC, Hu-Friedy Mfg. Co. LLC and Crosstex International, Inc., dated as of April 10, 2024 (filed as Exhibit 2.1 to STERIS plc Form 10-Q for the fiscal quarter ended June 30, 2024 filed August 8, 2024 (Commission File No. 001-38848) and incorporated herein by reference).

EQUITY PURCHASE AGREEMENT AMONG STERIS CORPORATION, HUFRIEDY GROUP HOLDING LLC AND SOLELY WITH RESPECT TO SECTION 2.

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

August 6, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fi

August 6, 2024 EX-99.1

STERIS Announces Financial Results for Fiscal 2025 First Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2025 First Quarter • Total revenue from continuing operations increased 8%; constant currency organic revenue grew 6% • As reported EPS from continuing operations increased to $1.41; adjusted EPS increased to $2.03 • Fiscal 2025 outlook reiterated DUBLIN, IRELAND - (August 6, 2024) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today

August 1, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

June 21, 2024 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K ý Annual Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the Twelve Month Period Ended December 31, 2023 OR o Transition Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the transition period from to Commission file number 001-38848 A. Full title of the plan and the address o

June 12, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant  ☒ Filed by a Party other than the Registrant  ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only   as permitted by Rule

June 12, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only as permitted by Rule 14a-6(e)(2)) ☐ Defini

May 31, 2024 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 70 Sir John Rogerson’s Quay, Dublin 2, Ireland DE21 6LY (Address of principal executive o

May 31, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 31, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Em

May 31, 2024 EX-1.01

STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2023 to December 31, 2023

Exhibit 1.01 STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2023 to December 31, 2023 Introduction This Conflict Minerals Report is filed by STERIS plc (“STERIS”) for the reporting period from January 1, 2023 to December 31, 2023 (the “Reporting Period”) as Exhibit 1.01 to STERIS’s Form SD pursuant to the requirements of Rule 13p-1 of the Securities Exchange Act of 19

May 29, 2024 EX-21.1

Subsidiaries of STERIS plc.

Exhibit 21.1 SUBSIDIARIES OF STERIS PLC STERIS plc has no parent company. As of March 31, 2024, its direct and indirect subsidiaries were as follows: 1666 E Touhy LLC Illinois Accelera Technologies, LLC Minnesota Accutron, Inc. Arizona Albert Browne Limited England and Wales American Sterilizer Company Pennsylvania Bioster-Mottahedoon Egypt SAE Egypt Birkova Products, LLC Indiana Bizworth Gammarad

May 29, 2024 EX-19.1

STERIS plc Insider Trading Policy

Exhibit 19.1 STERIS plc Insider Trading Policy BCP-10.2 Version # Effective Date Page 1 of 18 3 May 3, 2023 Purpose: The purpose of this Insider Trading Policy is to promote compliance with applicable securities laws by the Company and its subsidiaries and all directors, senior managers (including any manager who would be considered an “officer” as such term is defined under Rule 16a-1 of the Exch

May 29, 2024 EX-24.1

Power of Attorney

Exhibit 24.1 STERIS PLC POWER OF ATTORNEY FORM 10-K Each of the undersigned hereby makes, constitutes, and appoints Daniel A. Carestio, Michael J. Tokich, Karen L. Burton, and J. Adam Zangerle, and each of them, his or her true and lawful attorney, with full power of substitution, for and in his or her name, place, and stead, to affix, as attorney-in-fact, his or her signature in any and all capac

May 29, 2024 EX-97.1

filed as Exhibit 97.1 to STERIS plc Form 10-K for the year ended March 31, 2024 filed May 29, 2024 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 97.1 Compensation Clawback Policy Effective October 2, 2023 Purpose As required pursuant to the listing standards of the New York Stock Exchange (the “Stock Exchange”), Section 10D of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), and Rule 10D-1 under the Exchange Act, the Compensation and Organization Development Committee (the “Committee”) of the Board of Directors

May 29, 2024 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-38848 STERIS plc (Exact name of registrant as specified i

May 15, 2024 CORRESP

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland May 15, 2024 CORRESPONDENCE FILING VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Industrial Applications and Services 100 F Street, N.E. Washington,

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland May 15, 2024 CORRESPONDENCE FILING VIA EDGAR U.

May 15, 2024 CORRESP

CORRESP

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland May 15, 2024 CORRESPONDENCE FILING VIA EDGAR U.

May 8, 2024 EX-99.1

STERIS Announces Financial Results for Fiscal 2024 Fourth Quarter and Full Year

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2024 Fourth Quarter and Full Year • Total fiscal 2024 revenue increase 12% to $5.5 billion • Total fiscal 2024 U.S. GAAP earnings per diluted share of $3.81; adjusted earnings per diluted share increase to $8.83 • Targeted restructuring plan announced DUBLIN, IRELAND - (May 8, 2024) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) toda

May 8, 2024 8-K

Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 7, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

April 11, 2024 EX-99.1

STERIS to Sell Dental Segment to an affiliate of Peak Rock Capital • Transaction expected to close in STERIS’s first quarter of fiscal 2025 • Divestiture allows STERIS to focus on Customers within core markets • Proceeds primarily to be used to repay

Exhibit 99.1 STERIS to Sell Dental Segment to an affiliate of Peak Rock Capital • Transaction expected to close in STERIS’s first quarter of fiscal 2025 • Divestiture allows STERIS to focus on Customers within core markets • Proceeds primarily to be used to repay debt DUBLIN, IRELAND—(April 11, 2024)—STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announced that the Company has entered in

April 11, 2024 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 10, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

April 9, 2024 CORRESP

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland April 9, 2024 CORRESPONDENCE FILING VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Industrial Applications and Services 100 F Street, N.E. Washington

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland April 9, 2024 CORRESPONDENCE FILING VIA EDGAR U.

April 9, 2024 CORRESP

CORRESP

STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland April 9, 2024 CORRESPONDENCE FILING VIA EDGAR U.

February 13, 2024 SC 13G/A

STE / STERIS plc / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01997-sterisplc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 8)* Name of issuer: STERIS PLC Title of Class of Securities: Common Stock CUSIP Number: G8473T100 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box to designate the rule purs

February 9, 2024 SC 13G/A

STE / STERIS plc / MASSACHUSETTS FINANCIAL SERVICES CO /MA/ - SEC SCHEDULE 13G Passive Investment

SC 13G/A 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* STERIS PLC (Name of Issuer) Common Stock (Title of Class of Securities) G8473T100 (CUSIP Number) December 29, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

February 8, 2024 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated February 8, 2024 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

February 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended December 31, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

February 7, 2024 EX-99.1

STERIS Announces Financial Results for Fiscal 2024 Third Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2024 Third Quarter • Third quarter revenue increases 15% as reported; 10% constant currency organic • As reported diluted earnings per share increased to $1.42; adjusted earnings per share increased to $2.22 • Fiscal 2024 outlook updated DUBLIN, IRELAND - (February 7, 2024) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announc

February 7, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 7, 2024 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

January 30, 2024 SC 13G/A

STE / STERIS plc / WCM INVESTMENT MANAGEMENT, LLC - FORM SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* STERIS plc (Name of Issuer) Common (Title of Class of Securities) G8473T100 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

November 7, 2023 8-K/A

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 27, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission

November 7, 2023 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated November 7, 2023 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

November 7, 2023 EX-99.1

STERIS Announces Financial Results for Fiscal 2024 Second Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2024 Second Quarter • Second quarter revenue growth of 12% as reported and 8% constant currency organic • As reported diluted earnings per share increased to $1.16; adjusted earnings increased to $2.03 • Fiscal 2024 outlook maintained DUBLIN, IRELAND - (November 7, 2023) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announced

November 7, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numb

November 7, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

November 7, 2023 EX-10.1

Description of STERIS plc Non-Employee Director Compensation Program (filed as Exhibit 10.1 to STERIS plc Form 10-Q for the fiscal quarter ended September 30, 2023 (Commission File No. 001-38848) and incorporated herein by reference).*

Exhibit 10.1 Description of STERIS plc Non-Employee Director Compensation Program Summarized below is the Director compensation program for STERIS plc (“STERIS”) non-employee Directors for the term of office beginning July 27, 2023. Director retainer fees have been increased for the 2023-2024 term of office. An annual retainer of $323,000 is payable to each non-employee Director other than the Cha

August 8, 2023 EX-10.3

Amendment No. 2, dated as of May 3, 2023, to Credit Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent.

ste6302023ex103 EXECUTION VERSION AMENDMENT NO. 2 THIS AMENDMENT NO. 2 (this “Agreement”), dated as of May 3, 2023, is entered into by STERIS PLC, a public limited company organized under the laws of Ireland (“STERIS plc”), STERIS LIMITED, a private limited company organized under the laws of England and Wales (“STERIS Limited”), STERIS CORPORATION, an Ohio corporation (“STERIS Corporation”), STER

August 8, 2023 EX-2.1

Amended and Restated Asset Purchase Agreement by and between STERIS Corporation; Becton, Dickinson and Company; and STERIS plc, solely for the purposes set forth in Section 12.21, dated as of August 2, 2023 (filed as Exhibit 2.1 to STERIS plc Form 10-Q for the fiscal quarter ended June 30, 2023 filed August 8, 2023 (Commission File No. 001-38848) and incorporated herein by reference).

AMENDED & RESTATED ASSET PURCHASE AGREEMENT BY AND BETWEEN STERIS CORPORATION (“PURCHASER”); BECTON, DICKINSON AND COMPANY (“SELLER”); AND STERIS PLC (“PARENT”), solely for the purposes set forth in Section 12.

August 8, 2023 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated August 8, 2023 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for the

August 8, 2023 EX-10.1

Amendment No. 1, dated as of May 3, 2023, to Delayed Draw Term Loan Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative

EXECUTION VERSION AMENDMENT NO. 1 THIS AMENDMENT NO. 1 (this “Agreement”), dated as of May 3, 2023, is entered into by STERIS PLC, a public limited company organized under the laws of Ireland (“STERIS plc”), STERIS LIMITED, a private limited company organized under the laws of England and Wales (“STERIS Limited”), STERIS CORPORATION, an Ohio corporation (“STERIS Corporation”), STERIS IRISH FINCO U

August 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

August 8, 2023 EX-10.2

Amendment No. 1, dated as of May 3, 2023, to Term Loan Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent.

ste6302023ex102 EXECUTION VERSION AMENDMENT NO. 1 THIS AMENDMENT NO. 1 (this “Agreement”), dated as of May 3, 2023, is entered into by STERIS PLC, a public limited company organized under the laws of Ireland (“STERIS plc”), STERIS LIMITED, a private limited company organized under the laws of England and Wales (“STERIS Limited”), STERIS CORPORATION, an Ohio corporation (“STERIS Corporation”), STER

August 1, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fi

August 1, 2023 EX-99.1

STERIS Announces Financial Results for Fiscal 2024 First Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2024 First Quarter • First quarter revenue growth of 11% as reported and constant currency organic • As reported diluted earnings per share increased to $1.25; adjusted earnings increased to $2.00 • Fiscal 2024 outlook updated to reflect acquisition of BD surgical instrumentation assets DUBLIN, IRELAND - (August 1, 2023) - STERIS plc (NYSE

July 27, 2023 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 27, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

July 27, 2023 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2023 STERIS plc (Exact N

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

June 23, 2023 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K ý Annual Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the Twelve Month Period Ended December 31, 2022 OR o Transition Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the transition period from to Commission file number 001-38848 A. Full title of the plan and the address o

June 20, 2023 EX-2.1

Asset Purchase Agreement, dated June 15, 2023, by and between STERIS plc, STERIS Corporation and Becton, Dickinson and Company.

EX-2.1 Exhibit 2.1 ASSET PURCHASE AGREEMENT BY AND BETWEEN STERIS CORPORATION (“PURCHASER”); BECTON, DICKINSON AND COMPANY (“SELLER”); AND STERIS PLC (“PARENT”), solely for the purposes set forth in Section 12.21 Dated as of June 15, 2023 TABLE OF CONTENTS ARTICLE 1. THE TRANSACTION AGREEMENT 1 1.1 Purchased Assets 1 1.2 Excluded Assets 3 1.3 Excluded Liabilities 4 1.4 Non-Assignable Assets 5 1.5

June 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2023 STERIS plc (Exact N

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 15, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

June 20, 2023 EX-99.1

STERIS Expands Healthcare Products Offering with Acquisition of Surgical Instrumentation Assets from Becton, Dickinson and Company for $540 million

EX-99.1 Exhibit 99.1 STERIS Expands Healthcare Products Offering with Acquisition of Surgical Instrumentation Assets from Becton, Dickinson and Company for $540 million • A natural extension for STERIS in the operating room and sterile processing department • A primarily consumables product portfolio • Transaction expected to close by September 30, 2023 DUBLIN, IRELAND - (June 20, 2023) - STERIS p

June 7, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

June 7, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only as permitted by Rule 14a

May 31, 2023 EX-1.01

STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2022 to December 31, 2022

EX-1.01 Exhibit 1.01 STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2022 to December 31, 2022 Introduction This Conflict Minerals Report is filed by STERIS plc (“STERIS”) for the reporting period from January 1, 2022 to December 31, 2022 (the “Reporting Period”) as Exhibit 1.01 to STERIS’s Form SD pursuant to the requirements of Rule 13p-1 of the Securities Exchange A

May 31, 2023 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File Number) (IRS Employer Identification No.) 70 Sir John Rogerson’s Quay, Dublin 2, Ireland D02 R296 (Address of princ

May 26, 2023 EX-10.17

Form of STERIS plc Nonqualified Stock Option Agreement for Employees (filed as Exhibit 10.17 to STERIS plc Form 10-K for the fiscal year ended March 31, 2023 (Commission File No. 001-38848) and incorporated herein by reference).*

Exhibit 10.17 FORM OF STERIS PLC NONQUALIFIED STOCK OPTION AGREEMENT FOR EMPLOYEES – , This Agreement (“Agreement”) is between STERIS plc (“STERIS”) and (“Optionee”), with respect to the grant of a Nonqualified Stock Option by STERIS to Optionee pursuant to the STERIS plc 2006 Long-Term Equity Incentive Plan, as Amended and Restated Effective August 2, 2016, and as further amended from time to tim

May 26, 2023 EX-21.1

Subsidiaries of STERIS plc.

Exhibit 21.1 SUBSIDIARIES OF STERIS PLC STERIS plc has no parent company. As of March 31, 2023, its direct and indirect subsidiaries were as follows: 1666 E Touhy LLC Illinois Accelera Technologies, LLC Minnesota Accutron, Inc. Arizona Albert Browne Limited England and Wales American Sterilizer Company Pennsylvania Bioster-Mottahedoon Egypt SAE Egypt Birkova Products, LLC Indiana Bizworth Gammarad

May 26, 2023 EX-24.1

Power of Attorney

Exhibit 24.1 STERIS PLC POWER OF ATTORNEY FORM 10-K Each of the undersigned hereby makes, constitutes, and appoints Daniel A. Carestio, Michael J. Tokich, Karen L. Burton, and J. Adam Zangerle, and each of them, his or her true and lawful attorney, with full power of substitution, for and in his or her name, place, and stead, to affix, as attorney-in-fact, his or her signature in any and all capac

May 26, 2023 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-38848 STERIS plc (Exact name of registrant as specified i

May 26, 2023 EX-10.16

Form of STERIS plc Restricted Stock Agreement for Employees (filed as Exhibit 10.16 to STERIS plc Form 10-K for the fiscal year ended March 31, 2023 (Commission File No. 001-38848) and incorporated herein by reference).*

Exhibit 10.16 FORM OF STERIS plc RESTRICTED STOCK AGREEMENT FOR EMPLOYEES - , This Agreement (“Agreement”) is between STERIS plc (“STERIS”) and < firstname> < lastname> (“Grantee”), with respect to the grant of shares of STERIS restricted stock to Grantee pursuant to the STERIS plc 2006 Long-Term Equity Incentive Plan, as Assumed, Amended and Restated Effective March 28, 2019, and as further amend

May 26, 2023 EX-10.24

Amendment No. 2 to STERIS plc Management Incentive Compensation Plan (As Assumed, Amended and Restated Effective March 28, 2019), dated May 8, 2023 (filed

Exhibit 10.24 AMENDMENT NO. 2 TO STERIS PLC MANAGEMENT INCENTIVE COMPENSATION PLAN (As Assumed, Amended and Restated Effective March 28, 2019) WHEREAS, on March 28, 2019, the Redomiciliation of STERIS plc, a public limited company organized under the laws of England and Wales, from the United Kingdom to Ireland (the “Redomiciliation”) pursuant to a court-approved scheme of arrangement under Englis

May 10, 2023 EX-99.1

STERIS Announces Financial Results for Fiscal 2023 Fourth Quarter and Full Year

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2023 Fourth Quarter and Full Year • Fourth quarter as reported revenue increased 14%; 16% constant currency organic revenue growth • Fourth quarter as reported earnings per share of $1.88; adjusted EPS of $2.30 • Fiscal 2024 Outlook provided DUBLIN, IRELAND - (May 10, 2023) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announc

May 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2023 STERIS plc (Exact Na

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 10, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

May 3, 2023 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Emp

May 3, 2023 EX-99.1

STERIS Appoints Esther M. Alegria, Ph.D. to Board of Directors

EX-99.1 Exhibit 99.1 STERIS Appoints Esther M. Alegria, Ph.D. to Board of Directors DUBLIN, IRELAND – May 3, 2023 – STERIS plc (NYSE: STE) (“STERIS” or the “Company”) announced today that Esther M. Alegria, Ph.D. has been elected to the Board of Directors, effective today. “We are pleased to welcome Dr. Alegria to our Board,” said Mohsen Sohi, Chairman of STERIS. “She brings over three decades of

February 10, 2023 SC 13G/A

STE / Steris PLC / WCM INVESTMENT MANAGEMENT, LLC - FORM SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* STERIS plc (Name of Issuer) Common (Title of Class of Securities) G8473T100 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

February 9, 2023 SC 13G/A

STE / Steris PLC / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01966-sterisplc.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 7)* Name of issuer: STERIS plc Title of Class of Securities: Common Stock CUSIP Number: G8473T100 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box to designate the rule purs

February 8, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2023 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

February 8, 2023 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated February 8, 2023 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

February 8, 2023 EX-99.1

STERIS Announces Financial Results for Fiscal 2023 Third Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2023 Third Quarter • As reported revenue increased 1%; 7% constant currency organic revenue growth • As reported earnings per share of $1.24; adjusted EPS of $2.02 • Updated outlook provided DUBLIN, IRELAND - (February 8, 2023) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announced financial results for its fiscal 2023 third

February 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended December 31, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

February 8, 2023 SC 13G

STE / Steris PLC / MASSACHUSETTS FINANCIAL SERVICES CO /MA/ - SEC SCHEDULE 13G Passive Investment

SC 13G 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* STERIS PLC (Name of Issuer) Common Stock (Title of Class of Securities) G8473T100 (CUSIP Number) December 30, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate th

November 9, 2022 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated November 9, 2022 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

November 9, 2022 EX-10.4

Description of STERIS Non-Employee Director Compensation Program*

EXHIBIT 10.4 Description of STERIS plc Non-Employee Director Compensation Program Summarized below is the Director compensation program for STERIS plc (?STERIS?) non-employee Directors for the term of office beginning July 28, 2022. Director retainer fees have been increased for the 2022-2023 term of office. An annual retainer of $315,000 is payable to each non-employee Director other than the Cha

November 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numb

November 9, 2022 EX-99.1

STERIS Announces Financial Results for Fiscal 2023 Second Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2023 Second Quarter ? As reported revenue was flat; 7% constant currency organic revenue growth ? As reported loss per share of ($3.15); adjusted EPS of $1.99 ? As reported loss includes an impairment charge of $490.6 million related to the Dental segment DUBLIN, IRELAND - (November 9, 2022) - STERIS plc (NYSE: STE) (?STERIS? or the ?Compa

November 9, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

August 8, 2022 EX-10.3

Form of Indemnification Agreement between STERIS Corporation and each of its directors and certain executive officers (filed as Exhibit 10.3 to Form 10-Q for the fiscal quarter ended June 30, 2022 (Commission File No. 001-14643) and incorporated herein by reference). *

Exhibit 10.3 DIRECTOR AND OFFICER INDEMNIFICATION AGREEMENT This Director and Officer Indemnification Agreement, dated as of , 20 (this ?Agreement?), is made by and between STERIS Corporation, an Ohio corporation (the ?Company?), and (?Indemnitee?). RECITALS: A. In recognition of the need for corporations to be able to induce capable and responsible persons to accept and continue in positions in c

August 8, 2022 EX-10.2

Form of Deed of Indemnification for STERIS plc directors and executive officers (filed as Exhibit 10.2 to STERIS plc Form 10-Q for the fiscal quarter ended June 30, 2022)(Commission File No. 001-38848) and incorporated herein by reference).*

Exhibit 10.2 DATED STERIS plc and [Insert Name] DEED OF INDEMNIFICATION MATHESON 70 Sir John Rogerson?s Quay Dublin 2 Ireland TEL: + 353 1 232 2000 FAX: +353 1 232 3333 53466063.3 46477852.1 CONTENTS Page No 1 Interpretation ............................................................................................................................. 1 2 Agreement to Serve ..........................

August 8, 2022 EX-10.1

Form of Deed of Indemnification for STERIS plc directors and executive officers (filed as Exhibit 10.1 to STERIS plc Form 10-Q for the fiscal quarter ended June 30, 2022 (Commission File No. 001-38848) and incorporated herein by reference). *

Exhibit 10.1 DATED STERIS plc and [Insert Name] DEED OF INDEMNIFICATION MATHESON 70 Sir John Rogerson?s Quay Dublin 2 Ireland TEL: + 353 1 232 2000 FAX: +353 1 232 3333 56258095.1 46477852.1 CONTENTS Page No 1 Interpretation ............................................................................................................................. 1 2 Agreement to Serve ..........................

August 8, 2022 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated August 8, 2022 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for the

August 8, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

August 2, 2022 EX-99.1

STERIS Announces Financial Results for Fiscal 2023 First Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2023 First Quarter • First quarter revenue increases 19% as reported; 6% constant currency organic • As reported EPS of $1.10; adjusted EPS of $1.90 • Updated outlook provided DUBLIN, IRELAND - (August 2, 2022) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announced financial results for its fiscal 2023 first quarter ended Jun

August 2, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fi

July 29, 2022 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 28, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

June 24, 2022 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K ? Annual Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the Twelve Month Period Ended December 31, 2021 OR o Transition Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the transition period from to Commission file number 001-38848 A. Full title of the plan and the address o

June 7, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 d301219ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

June 7, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 d290847ddef14a.htm DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Com

May 31, 2022 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation

SD 1 d350242dsd.htm FORM SD UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 70 Sir John Rogerson’s Quay, Dublin 2, Ireland DE21 6LY (Addr

May 31, 2022 EX-21.1

Subsidiaries of STERIS plc.

Exhibit 21.1 SUBSIDIARIES OF STERIS PLC STERIS plc has no parent company. As of March 31, 2022, its direct and indirect subsidiaries(1) were as follows: Accelera Technologies LLC Minnesota Accutron, Inc. Arizona Albert Browne Limited England & Wales American Sterilizer Company Pennsylvania BHT Hygienetechnik Holding GmbH Germany Bioster Mottahedoon Egypt SAE Egypt Birkova Products Indiana Bizworth

May 31, 2022 EX-1.01

STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2021 to December 31, 2021

Exhibit 1.01 STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2021 to December 31, 2021 Introduction This Conflict Minerals Report is filed by STERIS plc (?STERIS?) for the reporting period from January 1, 2021 to December 31, 2021 (the ?Reporting Period?) as Exhibit 1.01 to STERIS?s Form SD pursuant to the requirements of Rule 13p-1 of the Securities Exchange Act of 19

May 31, 2022 EX-10.40

Amendment No. 1, dated as of January 1, 2022, to Credit Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent (filed as Exhibit 10.40 to Form 10-K filed May 31, 2022 (Commission File No. 001-38848) and incorporated herein by reference).

EXECUTION VERSIONEXHIBIT 10.40 AMENDMENT NO. 1 THIS AMENDMENT NO. 1 (this ?Agreement?), dated as of January 1, 2022, is entered into by JPMORGAN CHASE BANK, N.A., as administrative agent (in such capacity, the ?Administrative Agent?). RECITALS WHEREAS, the STERIS PLC, a public limited company organized under the laws of Ireland (?STERIS plc?), STERIS LIMITED, a private limited company organized un

May 31, 2022 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-38848 STERIS plc (Exact name of registrant as specified i

May 31, 2022 EX-24.1

Power of Attorney

Exhibit 24.1 STERIS PLC POWER OF ATTORNEY FORM 10-K Each of the undersigned hereby makes, constitutes, and appoints Daniel A. Carestio, Michael J. Tokich, Karen L. Burton, J. Adam Zangerle, and Ronald E. Snyder, and each of them, his or her true and lawful attorney, with full power of substitution, for and in his or her name, place, and stead, to affix, as attorney-in-fact, his or her signature in

May 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 11, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

May 12, 2022 EX-99.1

STERIS Announces Financial Results for Fiscal 2022 Fourth Quarter and Full Year

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2022 Fourth Quarter and Full Year ? Fourth quarter revenue increases 39% as reported; 11% constant currency organic ? As reported EPS of $0.52; adjusted EPS of $2.04 ? Company provides FY23 Outlook DUBLIN, IRELAND - (May 11, 2022) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced financial results for its fiscal 2022 fou

February 10, 2022 SC 13G/A

STE / Steris PLC / WCM INVESTMENT MANAGEMENT, LLC - FORM SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* STERIS plc (Name of Issuer) Common (Title of Class of Securities) G8473T100 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

February 10, 2022 SC 13G/A

STE / Steris PLC / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 6)* Name of issuer: STERIS plc Title of Class of Securities: Common Stock CUSIP Number: G8473T100 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ??Rule 13d

February 9, 2022 EX-22.1

List of Guarantor Subsidiaries with respect to the 2.700% Notes due 2031 and 3.750% Notes due 2051 issued by STERIS Irish Finco Unlimited Company

Exhibit 22.1 List of Guarantor Subsidiaries with respect to the 2.700% Senior Notes due 2031 and 3.750% Senior Notes due 2051 issued by STERIS Irish FinCo Unlimited Company Senior Notes Issued Under Issuer Guarantors 2021 Indenture STERIS Irish FinCo Unlimited Company STERIS plc, STERIS Corporation, STERIS Limited

February 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended December 31, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number

February 9, 2022 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated February 9, 2022 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

February 8, 2022 EX-99.1

STERIS Announces Financial Results for Fiscal 2022 Third Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2022 Third Quarter ? Third quarter revenue increases 49% as reported; 9% constant currency organic ? As reported EPS of $1.42; adjusted EPS of $2.12 ? Outlook for FY22 raised DUBLIN, IRELAND - (February 8, 2022) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced financial results for its fiscal 2022 third quarter ended De

February 8, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

January 4, 2022 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 3, 2022 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission F

December 20, 2021 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

November 8, 2021 EX-10.3

Transition Agreement effective July 31, 2021, by and among STERIS Corporation, STERIS plc and Walter M Rosebrough Jr.

EXHIBIT 10.3 TRANSITION AGREEMENT THIS TRANSITION AGREEMENT ("Agreement") is made as of the 29th day of January 2021 and will take effect on the 31st day of July, 2021 (the "Effective Date") by and between STERIS Corporation, an Ohio corporation ("Employer"), and STERIS plc, an Irish public limited company ("Parent", and together with the Employer, "Company"), and Walter M Rosebrough, Jr. ("Execut

November 8, 2021 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated November 8, 2021 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

November 8, 2021 EX-22.1

List of Guarantor Subsidiaries with respect to the 2.700% Notes due 2031 and 3.750% Notes due 2051 issued by STERIS Irish Finco Unlimited Company

Exhibit 22.1 List of Guarantor Subsidiaries with respect to the 2.700% Senior Notes due 2031 and 3.750% Senior Notes due 2051 issued by STERIS Irish FinCo Unlimited Company Senior Notes Issued Under Issuer Guarantors 2021 Indenture STERIS Irish FinCo Unlimited Company STERIS plc, STERIS Corporation, STERIS Limited

November 8, 2021 EX-10.1

Description of STERIS Non-Employee Director Compensation Program

Exhibit 10.1 Description of STERIS Non-Employee Director Compensation Program The Director compensation program for STERIS plc (?STERIS?) non-employee Directors for the term of office beginning July 29, 2021 is summarized below. An annual retainer of $300,000 is payable for the 2021-2022 term of office to each non- employee Director other than the Chairman of the Board. An annual retainer of $450,

November 8, 2021 EX-10.2

Amendment No. 1 to STERIS plc 2006 Long-Term Equity Incentive Plan (as Assumed, Amended and Restated Effective March 28, 2019), effective July 27, 2021 (filed as Exhibit 10.2 to Form 10-Q for the fiscal quarter ended September 30, 2021 (Commission File No. 001-38848) and incorporated herein by reference).*

EXHIBIT 10.2 AMENDMENT NO. 1 TO STERIS PLC 2006 LONG-TERM EQUITY INCENTIVE PLAN (AS ASSUMED, AMENDED AND RESTATED EFFECTIVE MARCH 28, 2019) (?PLAN?) WHEREAS, STERIS plc (the ?Company?) assumed, amended and restated the Plan effective March 28, 2019; and WHEREAS, the Compensation and Organization Development Committee of the Board of Directors of the Company authorized this Amendment of the Plan on

November 8, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numb

November 2, 2021 EX-99.1

STERIS Announces Financial Results for Fiscal 2022 Second Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2022 Second Quarter ? Second quarter revenue increases 58% as reported; 12% constant currency organic ? As reported EPS of $0.69; adjusted EPS of $1.99 ? Company reiterates fiscal 2022 outlook DUBLIN, IRELAND - (November 2, 2021) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced financial results for its fiscal 2022 seco

November 2, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

August 9, 2021 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated August 9, 2021 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for the

August 9, 2021 EX-99.1

STERIS Announces Financial Results for Fiscal 2022 First Quarter

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2022 First Quarter ? First quarter revenue increases 45% as reported; 21% constant currency organic ? Cantel Medical integration on track ? Company increases outlook and raises quarterly dividend DUBLIN, IRELAND - (August 9, 2021) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced financial results for its fiscal 2022 fir

August 9, 2021 EX-22.1

List of Guarantor Subsidiaries with respect to the 2.700% Notes due 2031 and 3.750% Notes due 2051 issued by STERIS Irish Finco Unlimited Company.

Exhibit 22.1 List of Guarantor Subsidiaries with respect to the 2.700% Senior Notes due 2031 and 3.750% Senior Notes due 2051 issued by STERIS Irish FinCo Unlimited Company Senior Notes Issued Under Issuer Guarantors 2021 Indenture STERIS Irish FinCo Unlimited Company STERIS plc, STERIS Corporation, STERIS Limited

August 9, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 9, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission Fi

August 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

August 2, 2021 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

August 2, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 29, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS E

June 15, 2021 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K

Securities and Exchange Commission Washington, D. C. 20549 FORM 11-K ? Annual Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the Twelve Month Period Ended December 31, 2020 OR o Transition Report Pursuant to Section 15(d) of The Securities Exchange Act of 1934 For the transition period from to Commission file number 001-38848 A. Full title of the plan and the address o

June 8, 2021 EX-4.1

First Supplemental Indenture, dated June 2, 2021, by and among Cantel Medical Corp. (now known as Cantel Medical LLC), STERIS plc and Wells Fargo, National Association, as trustee.

Exhibit 4.1 CANTEL MEDICAL LLC AND STERIS PLC AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee FIRST SUPPLEMENTAL INDENTURE June 2, 2021 3.25% Convertible Senior Notes due 2025 FIRST SUPPLEMENTAL INDENTURE, dated as of June 2, 2021 (this ?First Supplemental Indenture?), among CANTEL MEDICAL LLC, a Delaware limited liability company (formerly known as Cantel Medical Corp., the ?Company?), STE

June 8, 2021 EX-99.1

UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL DATA

Exhibit 99.1 UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL DATA The following unaudited condensed combined pro forma financial data (?pro forma financial data?) combines the historical consolidated financial positions and results of operations of STERIS plc (?STERIS?) and Cantel Medical Corp. (?Cantel?) as an acquisition by STERIS of Cantel. The transaction was announced on January 12, 2021 and

June 8, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Em

June 7, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 File

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confid

June 7, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of

June 2, 2021 EX-4.6

Omnibus Amendment to Cantel Medical Corp. 2016 Equity Incentive Plan and Cantel Medical Corp. 2020 Equity Incentive Plan

Exhibit 4.6 OMNIBUS AMENDMENT TO CANTEL MEDICAL CORP. 2016 EQUITY INCENTIVE PLAN AND CANTEL MEDICAL CORP. 2020 EQUITY INCENTIVE PLAN STERIS plc, a public limited company incorporated under the laws of Ireland (the ?Company?), hereby adopts this Omnibus Amendment (this ?Amendment?) to Cantel Medical Corp. 2016 Equity Incentive Plan (the ?2016 Plan?) and Cantel Medical Corp. 2020 Equity Incentive Pl

June 2, 2021 S-8

As filed with the Securities and Exchange Commission on June 2, 2021

As filed with the Securities and Exchange Commission on June 2, 2021 Registration No.

June 2, 2021 EX-24.1

Power of Attorney

EXHIBIT 24.1 STERIS PLC REGISTRATION STATEMENT ON FORM S-8 POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each of the undersigned officers and directors of STERIS plc, a public limited company organized under the laws or Ireland (the ?Registrant?), hereby constitutes and appoints Dr. Moshen M. Sohi, Walter M Rosebrough, Jr., Daniel A. Carestio, Michael J. Tokich, J. Adam Zangerle and K

June 1, 2021 EX-23.7

Consent of Centerview Partners LLC

Exhibit 23.7 Consent of Centerview Partners LLC The Board of Directors Cantel Medical Corp. 150 Clove Road Little Falls, NJ 07424 The Board of Directors: We hereby consent to the inclusion of our opinion letter, dated January 12, 2021, to the Board of Directors of Cantel Medical Corp. (“Cantel”) as Annex B to, and reference to such opinion letter under the headings “Summary—Opinion of Cantel’s Fin

June 1, 2021 S-4MEF

As filed with the Securities and Exchange Commission on June 1, 2021

As filed with the Securities and Exchange Commission on June 1, 2021 Registration No.

June 1, 2021 EX-15.1

LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the Registration Statement on Form S-4 filed pursuant to General Instruction K to Form S-4 and Rule 462(b) of the Securities Act of 1933 of our review reports dated August 7, 2020, November 6, 2020 and February 9, 2021 relating to th

June 1, 2021 EX-1.01

STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2020 to December 31, 2020

Exhibit 1.01 STERIS plc Conflict Minerals Report for the Reporting Period from January 1, 2020 to December 31, 2020 Introduction This Conflict Minerals Report is filed by STERIS plc (?STERIS?) for the reporting period from January 1, 2020 to December 31, 2020 (the ?Reporting Period?) as Exhibit 1.01 to STERIS?s Form SD pursuant to the requirements of Rule 13p-1 of the Securities Exchange Act of 19

June 1, 2021 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT STERIS plc (Exact name of registrant as specified in its charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.) 70 Sir John Rogerson?s Quay, Dublin 2, Ireland DE21 6LY (Address of principal executive o

May 28, 2021 EX-22.1

List of Guarantor Subsidiaries with respect to the 2.700% Notes due 2031 and 3.750% Notes due 2051 issued by STERIS Irish Finco Unlimited Company (filed as Exhibit 22.1 to Form 10-K for the fiscal year ended March 31, 2021 (Commission File No. 001-38848), and incorporated by reference).

Exhibit 22.1 List of Guarantor Subsidiaries with respect to the 2.700% Notes due 2031 and 3.750% Notes due 2051 issued by STERIS Irish Finco Unlimited Company Senior Notes Issued Under Issuer Guarantors 2021 Indenture STERIS Irish Finco Unlimited Company STERIS plc, STERIS Corporation, STERIS Limited

May 28, 2021 EX-18.1

LIFO Preferability Letter

Exhibit 18.1 May 28, 2021 The Board of Directors of STERIS plc 70 Sir John Rogerson?s Quay Dublin 2 Ireland Ladies and Gentlemen: Note 1 of the Notes to the consolidated financial statements of STERIS plc and subsidiaries included in its Annual Report on Form 10-K for the year ended March 31, 2021 describes a change in the method of accounting for inventory valuation from the last-in, first-out (L

May 28, 2021 EX-24.1

Power of Attorney

Exhibit 24.1 STERIS PLC POWER OF ATTORNEY FORM 10-K Each of the undersigned hereby makes, constitutes, and appoints Walter M Rosebrough, Jr., Daniel A. Carestio, Michael J. Tokich, Karen L. Burton, J. Adam Zangerle, Ronald E. Snyder, Julia Kipnis, and each of them, his or her true and lawful attorney, with full power of substitution, for and in his or her name, place, and stead, to affix, as attor

May 28, 2021 EX-4.5

Description of Securities Registered Under Section 12 of the Securities Exchange Act of 1934 (filed as Exhibit 4.5 to STERIS plc Form 10-K for the fiscal year ended March 31, 2021 (Commission File No. 001-38848), and incorporated herein by reference).

Exhibit 4.5 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES AND EXCHANGE ACT OF 1934 As of the date hereof, STERIS plc, a public limited company incorporated under the laws of Ireland, and its subsidiaries have three classes of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended: ordinary shares of STERIS plc and

May 28, 2021 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K

United States Securities and Exchange Commission Washington, D. C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission file number 001-38848 STERIS plc (Exact name of registrant as specified i

May 28, 2021 EX-21.1

Subsidiaries of STERIS plc.

Exhibit 21.1 SUBSIDIARIES OF STERIS PLC STERIS plc has no parent company. As of March 31, 2021, its direct and indirect subsidiaries(1) were as follows: Albert Browne Limited England & Wales American Sterilizer Company Pennsylvania Bioster Mottahedoon Egypt SAE Egypt Birkova Products Indiana Bizworth Gammarad Sdn Bhd Malaysia Black Diamond Video, Inc. California CLBV Limited England & Wales Contro

May 19, 2021 425

STERIS Announces Financial Results for Fiscal 2021 Fourth Quarter and Full Year

Filed by STERIS plc Commission File No. 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date 05/18/2021 STERIS Announces Financial Results for Fiscal 2021 Fourth Quarter and Full Year ? Fourth quarter revenue increases 6% as reported; full year increases 3% as reported ? Full year earnings per diluted

May 19, 2021 425

Corrected Transcript Total Pages: 15 19-May-2021 1-877-FACTSET www.callstreet.com Copyright © 2001-2021 FactSet CallStreet, LLC STERIS Plc (Ireland) (STE)Q4 2021 Earnings Call STERIS Plc (Ireland) (STE) Q4 2021 Earnings Call Corrected Transcript19-Ma

Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date 05/19/2021 Corrected Transcript Total Pages: 15 19-May-2021 1-877-FACTSET www.callstreet.com Copyright ? 2001-2021 FactSet CallStreet, LLC STERIS Plc (Ireland) (STE)Q4 2021 Earnings Call STERIS Plc (Ireland) (

May 18, 2021 EX-99.1

STERIS Announces Financial Results for Fiscal 2021 Fourth Quarter and Full Year

Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2021 Fourth Quarter and Full Year ? Fourth quarter revenue increases 6% as reported; full year increases 3% as reported ? Full year earnings per diluted share of $4.63 on a U.S. GAAP basis and $6.17 on an adjusted basis on effective tax rates of 23.3% and 20.7%, respectively ? Company provides outlook for fiscal 2022 including Cantel Medic

May 18, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission File

May 11, 2021 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS Emp

May 11, 2021 EX-99.1

STERIS Announces Changes to Board of Directors • David B. Lewis to retire at the Company’s 2021 Annual Meeting of Shareholders • Company appoints Paul E. Martin to Board

Exhibit 99.1 STERIS Announces Changes to Board of Directors ? David B. Lewis to retire at the Company?s 2021 Annual Meeting of Shareholders ? Company appoints Paul E. Martin to Board DUBLIN, IRELAND?(May 11, 2021)?STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced changes to its Board of Directors. David Lewis, Board member since 2010 has announced that he will not stand for electi

May 3, 2021 425

Merger Prospectus - 425

Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date 05/03/2021 Dear Cantel and STERIS Associates: Over the past few months, we have achieved a number of key objectives in our quest to complete the combination of STERIS and Cantel. We are excited to share that a

April 27, 2021 EX-99.1

STERIS Announces Preliminary Financial Results for Fiscal 2021

Exhibit 99.1 STERIS Announces Preliminary Financial Results for Fiscal 2021 ? Company expects to close the Cantel Medical acquisition by June 2, 2021, pending shareholder vote DUBLIN, IRELAND - (April 27, 2021) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced preliminary financial results for its fiscal 2021 year ending March 31, 2021. The Company expects to report that revenue

April 27, 2021 425

Merger Prospectus - 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 27, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

April 27, 2021 EX-99.1

STERIS Announces Preliminary Financial Results for Fiscal 2021

Exhibit 99.1 STERIS Announces Preliminary Financial Results for Fiscal 2021 ? Company expects to close the Cantel Medical acquisition by June 2, 2021, pending shareholder vote DUBLIN, IRELAND - (April 27, 2021) - STERIS plc (NYSE: STE) (?STERIS? or the ?Company?) today announced preliminary financial results for its fiscal 2021 year ending March 31, 2021. The Company expects to report that revenue

April 27, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 27, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

April 12, 2021 425

Merger Prospectus - 425

Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date: 04/12/2021 April 12, 2021 Dear Cantel Employees: Since we last reached out to you to share the news of our CEO succession plan in February, we have been very busy behind the scenes working to successfully clo

April 1, 2021 EX-4.2

First Supplemental Indenture, dated as of April 1, 2021, among STERIS Irish FinCo Unlimited Company, the guarantors party thereto and U.S. Bank National Association, as trustee (filed as Exhibit 4.2 to STERIS plc Form 8-K filed April 1, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 4.2 Execution Version STERIS IRISH FINCO UNLIMITED COMPANY AND THE GUARANTORS PARTY HERETO AND U.S. BANK NATIONAL ASSOCIATION, as Trustee FIRST SUPPLEMENTAL INDENTURE Dated as of April 1, 2021 $675,000,000 of 2.700% Senior Notes due 2031 $675,000,000 of 3.750% Senior Notes due 2051 THIS FIRST SUPPLEMENTAL INDENTURE (the ?First Supplemental Indenture?) is dated as of April 1, 2021 among STE

April 1, 2021 8-A12B

- 8-A12B

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 STERIS plc STERIS Irish FinCo Unlimited Company Ireland Ireland 98-1455064 98-1271422 (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organiz

April 1, 2021 425

Merger Prospectus - 425

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

April 1, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

April 1, 2021 424B3

LETTER TO STOCKHOLDERS OF CANTEL

TABLE OF CONTENTS Filed Pursuant to Rule 424(b)(3) Registration No. 333-253799 LETTER TO STOCKHOLDERS OF CANTEL Dear Stockholders: On January 12, 2021, Cantel Medical Corp., which is referred to as Cantel, and STERIS plc, Solar New US Holding Co, LLC and Crystal Merger Sub 1, LLC, which are referred to as STERIS, US Holdco and Crystal Merger Sub, respectively, entered into an Agreement and Plan of

April 1, 2021 EX-4.1

Indenture, dated as of April 1, 2021, among STERIS Irish FinCo Unlimited Company, the guarantors party thereto, and U.S. Bank National Association, as trustee (filed as Exhibit 4.1 to STERIS plc Form 8-K filed April 1, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 4.1 STERIS IRISH FINCO UNLIMITED COMPANY as Issuer AND THE GUARANTORS PARTY HERETO AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of April 1, 2021 DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE I DEFINITIONS 1 Section 1.01. Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 8 Section 2.01. Designation and Terms

April 1, 2021 EX-1.1

Underwriting Agreement, dated as of March 24, 2021, by and among STERIS Irish FinCo Unlimited Company, the guarantors party thereto, and J.P. Morgan Securities LLC, BofA Securities, Inc. and Citigroup Global Markets, Inc., as representatives of the several underwriters named therein.

Exhibit 1.1 Execution Version $1,350,000,000 STERIS Irish FinCo Unlimited Company 2.700% Senior Notes due 2031 3.750% Senior Notes due 2051 Underwriting Agreement March 24, 2021 J.P. Morgan Securities LLC BofA Securities, Inc. Citigroup Global Markets Inc. As Representatives of the several Underwriters listed in Schedule 1 hereto c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York

April 1, 2021 EX-5.3

Consent of Jones Day (included in Exhibit 5.3 hereof).

Exhibit 5.3 AUTHORISED AND REGULATED BY THE SOLICITORS REGULATION AUTHORITY SRA NO. 223597 21 TUDOR STREET ? LONDON EC4Y ODJ ? DX 67 LONDON/CHANCERY TELEPHONE: +44.020.7039.5959 ? FACSIMILE: +44.020.7039.5999 Date 1 April 2021 STERIS plc STERIS Irish FinCo Unlimited Company STERIS Corporation STERIS Limited c/o STERIS plc 70 Sir John Rogerson?s Quay Dublin 2 Ireland D02 R296 Re: $675,000,000 of 2.

March 30, 2021 CORRESP

[Signature Follows]

CORRESP 1 filename1.htm STERIS plc 70 Sir John Rogerson’s Quay Dublin 2 Ireland D02 R296 Tel: +351 1 232 2000 March 30, 2021 VIA EDGAR CORRESPONDENCE Securities and Exchange Commission Division of Corporation Finance 100 F Street, NE Washington, DC 20549 Attention: Dillon Hagius, Attorney Advisor Division of Corporation Finance Office of Life Sciences Re: STERIS plc Amendment No. 1 to Registration

March 30, 2021 S-4/A

- S-4/A

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 29, 2021 Registration No.

March 30, 2021 EX-23.7

Consent of Centerview Partners LLC

Exhibit 23.7 Consent of Centerview Partners LLC The Board of Directors Cantel Medical Corp. 150 Clove Road Little Falls, NJ 07424 The Board of Directors: We hereby consent to the inclusion of our opinion letter, dated January 12, 2021, to the Board of Directors of Cantel Medical Corp. (“Cantel”) as Annex B to, and reference to such opinion letter under the headings “Summary—Opinion of Cantel’s Fin

March 30, 2021 EX-15.1

LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION

EX-15.1 5 nt10018921x2ex15-1.htm EXHIBIT 15.1 Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in Amendment No. 1 to the Registration Statement (Form S-4 No. 333-253799) and related proxy statement/prospectus of STERIS plc for the registration of 14,287,997 shares of its common stock

March 26, 2021 424B5

CALCULATION OF REGISTRATION FEE Title of Each Class of Securities to be Registered Amount to be Registered Maximum Offering Price per Unit Maximum Aggregate Offering Price Amount of Registration Fee(1) 2.700% Senior Notes due 2031 $675,000,000 99.897

Form 424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-254608 CALCULATION OF REGISTRATION FEE Title of Each Class of Securities to be Registered Amount to be Registered Maximum Offering Price per Unit Maximum Aggregate Offering Price Amount of Registration Fee(1) 2.700% Senior Notes due 2031 $675,000,000 99.897% $674,304,750 $73,566.65 Guarantees of 2.700% Senior Notes

March 24, 2021 FWP

STERIS IRISH FINCO UNLIMITED COMPANY Pricing Term Sheet

Filed Pursuant to Rule 433 Registration Statement No. 333-254608 Pricing Term Sheet STERIS IRISH FINCO UNLIMITED COMPANY Pricing Term Sheet The information in this pricing term should be read together with (i) the preliminary prospectus supplement, dated March 24, 2021, as filed with the Securities and Exchange Commission (the ?SEC?) pursuant to Rule 424(b) under the Securities Act of 1933, as ame

March 24, 2021 424B5

STERIS Investor Relations 5960 Heisley Road Mentor, Ohio 44060 Telephone Number: +1 440 354 2600

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration No. 333-254608 The information in this preliminary prospectus supplement is not complete and may be changed. This preliminary prospectus supplement and the accompanying prospectus are not an offer to sell these securities and are not soliciting an offer to buy these securities in any jurisdiction where the offer or sale is not permitt

March 23, 2021 EX-24.1

Power of Attorney of Directors and Officers of STERIS plc

Exhibit 24.1 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that each of the undersigned directors and officers of STERIS plc, an Irish public limited company, does hereby constitute and appoint Walter M Rosebrough, Jr., Michael J. Tokich and J. Adam Zangerle, and each of them acting individually, as the true and lawful attorney-in-fact or attorneys-in-fact for each of the undersigned, with full po

March 23, 2021 EX-10.5

First Amendment dated as of March 19, 2021 to Amended and Restated Note Purchase Agreement, dated as of March 5, 2019, among STERIS Corporation and each of the institutions signatory thereto (filed as Exhibit 10.5 to Form 8-K filed March 23, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 10.5 EXECUTION VERSION STERIS CORPORATION FIRST AMENDMENT Dated as of March 19, 2021 to AMENDED AND RESTATED NOTE PURCHASE AGREEMENT Dated as of March 5, 2019 Re: $125,000,000 3.45% SENIOR NOTES, SERIES A-1, DUE MAY 14, 2025 $125,000,000 3.55% SENIOR NOTES, SERIES A-2, DUE MAY 14, 2027 $100,000,000 3.70% SENIOR NOTES, SERIES A-3, DUE MAY 14, 2030 FIRST AMENDMENT TO THE AMENDED AND RESTATED

March 23, 2021 EX-10.4

First Amendment dated as of March 19, 2021 to Amended and Restated Note Purchase Agreement, dated as of March 5, 2019, among STERIS Corporation and each of the institutions signatory thereto (filed as Exhibit 10.4 to Form 8-K filed March 23, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 10.4 EXECUTION VERSION STERIS CORPORATION FIRST AMENDMENT Dated as of March 19, 2021 to AMENDED AND RESTATED NOTE PURCHASE AGREEMENT Dated as of March 5, 2019 RE: $47,500,000 3.20% SENIOR NOTES, SERIES A-1A, DUE DECEMBER 4, 2022 $47,500,000 3.20% SENIOR NOTES, SERIES A-1B, DUE DECEMBER 4, 2022 $40,000,000 3.35% SENIOR NOTES, SERIES A-2A, DUE DECEMBER 4, 2024 $40,000,000 3.35% SENIOR NOTES,

March 23, 2021 EX-10.1

Delayed Draw Term Loan Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent (filed as Exhibit 10.1 to Form 8-K filed March 23, 2021 (Commission File No. 1-38848), and incorporated herein by reference).

Exhibit 10.1 Execution Version $750,000,000 TERM LOAN AGREEMENT Dated as of March 19, 2021 among STERIS PLC, as a Borrower, STERIS LIMITED, as a Borrower, STERIS CORPORATION, as a Borrower, STERIS IRISH FINCO UNLIMITED COMPANY, as a Borrower, The Guarantors Party Hereto, VARIOUS FINANCIAL INSTITUTIONS, as Lenders, and JPMORGAN CHASE BANK, N.A., as Administrative Agent BOFA SECURITIES, INC., CITIBA

March 23, 2021 EX-3.5

Amended and Restated Articles of Incorporation of STERIS Corporation, as filed with the Secretary of State of the State of Ohio on November 6, 2015

Exhibit 3.5 AMENDED AND RESTATED ARTICLES OF INCORPORATION OF STERIS CORPORATION ARTICLE I The name of the corporation (which is hereinafter referred to as the ?Corporation?) is: STERIS Corporation. ARTICLE II The place in Ohio where its principal office is to be located is the City of Mentor in Lake County. ARTICLE III The purpose of the Corporation shall be to engage in any lawful act or activit

March 23, 2021 EX-5.3

Opinion of Jones Day

Exhibit 5.3 Date 23 March 2021 STERIS plc STERIS Irish FinCo Unlimited Company STERIS Corporation STERIS Limited c/o STERIS plc 70 Sir John Rogerson?s Quay Dublin 2 Ireland D02 R296 Re: Registration Statement on Form S-3 filed by, amongst others, STERIS plc (a public limited company incorporated in Ireland, the ?Parent?), STERIS Irish FinCo Unlimited Company (a public unlimited company incorporate

March 23, 2021 EX-3.8

Articles of Association of STERIS Limited

Exhibit 3.8 STERIS LIMITED ARTICLES OF ASSOCIATION TABLE OF CONTENTS Page PRELIMINARY 1 1. DEFINITIONS 1 2. EXCLUSION OF MODEL ARTICLES 5 CAPITAL 5 3. LIABILITY OF MEMBERS 5 4. SHARE CAPITAL 5 5. ORDINARY SHARES 5 6. PREFERENCE SHARES 6 7. SECTION 551 AUTHORITY 6 8. SECTION 561 DISAPPLICATION 6 9. ALLOTMENT AFTER EXPIRY 7 10. DEFINITIONS FOR ARTICLES 5, 8 AND 9 7 11. ALLOTMENT POWERS?SECTION 551 A

March 23, 2021 EX-10.6

First Amendment dated as of March 19, 2021 to Amended and Restated Note Purchase Agreement, dated as of March 5, 2019, among STERIS Limited and each of the institutions signatory thereto (filed as Exhibit 10.6 to Form 8-K filed March 23, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 10.6 EXECUTION VERSION STERIS LIMITED (formerly known as STERIS plc) FIRST AMENDMENT Dated as of March 19, 2021 to AMENDED AND RESTATED NOTE PURCHASE AGREEMENT Dated as of March 5, 2019 RE: $50,000,000 3.93% SENIOR NOTES, SERIES A-1, DUE FEBRUARY 27, 2027 ?60,000,000 1.86% SENIOR NOTES, SERIES A-2, DUE FEBRUARY 27, 2027 $45,000,000 4.03% SENIOR NOTES, SERIES A-3, DUE FEBRUARY 27, 2029 ?20,

March 23, 2021 EX-24.2

Power of Attorney of Directors of STERIS Irish FinCo Unlimited

Exhibit 24.2 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that each of the undersigned directors of STERIS Irish FinCo Unlimited Company, a public unlimited company incorporated under the laws of Ireland, does hereby constitute and appoint Walter M Rosebrough, Jr., Michael J. Tokich and J. Adam Zangerle, and each of them acting individually, as the true and lawful attorney-in-fact or attorneys-in

March 23, 2021 EX-3.4

Articles of Association of STERIS Irish FinCo Unlimited Company, adopted with effect from March 18, 2021

Exhibit 3.4 ARTICLES OF ASSOCIATION OF STERIS IRISH FINCO UNLIMITED COMPANY 1 Interpretation 1.1 In this Constitution: ?Act? means the Companies Act 2014 and every statutory modification or re-enactment thereof for the time being in force; ?Company? means Steris Irish FinCo Unlimited Company; ?Constitution? has the meaning set out in regulation 1.2; ?director? means a director of the Company and t

March 23, 2021 EX-15.1

Acknowledgement Letter of Ernst & Young LLP relating to STERIS plc’s unaudited interim financial information

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the Registration Statement (Form S-3) and related Prospectus of STERIS plc for the registration of debt securities, guarantees of debt securities, ordinary shares, preferred shares, warrants, and units of our reports dated August 7,

March 23, 2021 EX-10.2

Term Loan Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent (filed as Exhibit 10.2 to Form 8-K filed March 23, 2021 (Commission File No. 1-38848), and incorporated herein by reference).

Exhibit 10.2 Execution Version $550,000,000 TERM LOAN AGREEMENT Dated as of March 19, 2021 among STERIS PLC, as a Borrower, STERIS LIMITED, as a Borrower, STERIS CORPORATION, as a Borrower, STERIS IRISH FINCO UNLIMITED COMPANY, as a Borrower, The Guarantors Party Hereto, VARIOUS FINANCIAL INSTITUTIONS, as Lenders, and JPMORGAN CHASE BANK, N.A., as Administrative Agent BOFA SECURITIES, INC., CITIBA

March 23, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 19, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IRS

March 23, 2021 EX-25.1

Form T-1 Statement of Eligibility under Trust Indenture Act of 1939 of Trustee under STERIS plc Debt Securities Indenture

Exhibit 25.1 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ? Check if an Application to Determine Eligibility of a Trustee Pursuant to Section 305(b)(2) U.S. BANK NATIONAL ASSOCIATION (Exact name of Trustee as specified in its charter) 31-0841368 I.R.S. Employer Identif

March 23, 2021 EX-3.3

Memorandum of Association of STERIS Irish Finco Unlimited Company, adopted with effect from March 18, 2021

Exhibit 3.3 MEMORANDUM OF ASSOCIATION OF STERIS IRISH FINCO UNLIMITED COMPANY 1 The name of the company is Steris Irish FinCo Unlimited Company (the ?Company?). 2 The Company is a public unlimited company having a share capital registered under Part 19 of the Companies Act 2014. 3 The objects for which the Company is established are: 3.1 To provide financing for STERIS Group activities. 3.2 To car

March 23, 2021 EX-4.1

Form of STERIS plc Debt Securities Indenture

Exhibit 4.1 STERIS PLC as Issuer AND THE GUARANTORS PARTY HERETO AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of , 20 DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE I DEFINITIONS 1 Section 1.01. Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 8 Section 2.01. Designation and Terms of Securities 8 Section 2.02. Form

March 23, 2021 EX-10.3

Credit Agreement, dated as of March 19, 2021, among STERIS plc, STERIS Limited, STERIS Corporation, STERIS Irish FinCo Unlimited Company, the lenders party thereto and JPMorgan Chase Bank, N.A., as administrative agent (filed as Exhibit 10.3 to Form 8-K filed March 23, 2021 (Commission File No. 1-38848), and incorporated herein by reference).

Exhibit 10.3 Execution Version $1,250,000,000 CREDIT AGREEMENT Dated as of March 19, 2021 among STERIS PLC, as a Borrower, STERIS LIMITED, as a Borrower, STERIS CORPORATION, as a Borrower, STERIS IRISH FINCO UNLIMITED COMPANY, as a Borrower, The Guarantors Party Hereto, VARIOUS FINANCIAL INSTITUTIONS, as Lenders, and JPMORGAN CHASE BANK, N.A., as Administrative Agent BOFA SECURITIES, INC., CITIBAN

March 23, 2021 EX-3.2

Certificate of Incorporation on Re-registration as a Public Unlimited Company of STERIS Irish Finco Unlimited Company, adopted with effect from March 18, 2021

Exhibit 3.2 Number: 570385 Certificate of Incorporation Public unlimited company with a share capital I hereby certify that STERIS IRISH FINCO formerly registered as ULC - Private Unlimited Company has this day been re-registered under the Companies Act 2014 as Public unlimited company with a share capital Given under my hand at Dublin, this Thursday 18 March 2021 for Registrar of Companies Signed

March 23, 2021 EX-3.7

Certificate of Incorporation on re-registration of a public company as a private company and registration of order of court and statement of capital of STERIS Limited, dated as of March 26, 2019

Exhibit 3.7 File Copy CERTIFICATE OF INCORPORATION OF A PRIVATE LIMITED COMPANY Company Number 9257343 The Registrar of Companies for England and Wales, hereby certifies that SOLAR NEW HOLDCO LIMITED is this day incorporated under the Companies Act 2006 as a private company, that the company is limited by shares, and the situation of its registered office is in England and Wales Given at Companies

March 23, 2021 S-3ASR

- S-3ASR

Table of Contents As filed with the Securities and Exchange Commission on March 23, 2021 Registration No.

March 23, 2021 EX-24.4

Power of Attorney of Directors of STERIS Limited

EX-24.4 21 d124684dex244.htm EX-24.4 Exhibit 24.4 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that each of the undersigned directors of STERIS Limited, a private limited company incorporated under the laws of England and Wales, does hereby constitute and appoint Walter M Rosebrough, Jr., Michael J. Tokich and J. Adam Zangerle, and each of them acting individually, as the true and lawful attorney

March 23, 2021 EX-24.3

Power of Attorney of Directors and Officers of STERIS Corporation

Exhibit 24.3 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that each of the undersigned directors and officers of STERIS Corporation, an Ohio corporation, does hereby constitute and appoint Walter M Rosebrough, Jr., Michael J. Tokich and J. Adam Zangerle, and each of them acting individually, as the true and lawful attorney-in-fact or attorneys-in-fact for each of the undersigned, with full power

March 23, 2021 EX-4.2

Form of STERIS Irish FinCo Unlimited Company Debt Securities Indenture

Exhibit 4.2 STERIS IRISH FINCO UNLIMITED COMPANY as Issuer AND THE GUARANTORS PARTY HERETO AND U.S. BANK NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of , 20 DEBT SECURITIES TABLE OF CONTENTS Page ARTICLE I DEFINITIONS 1 Section 1.01. Definitions of Terms 1 ARTICLE II ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 8 Section 2.01. Designation and Terms of Secur

March 23, 2021 EX-3.6

Amended and Restated Code of Regulations of STERIS Corporation

Exhibit 3.6 AMENDED AND RESTATED CODE OF REGULATIONS OF STERIS CORPORATION ARTICLE I MEETINGS OF SHAREHOLDERS Section 1. Place of Meeting. Meetings of the shareholders may be held either within or without the State of Ohio. Section 2. Annual Meeting. The annual meeting of the shareholders, whereat the shareholders shall elect a Board of Directors, and transact such other business as may properly b

March 23, 2021 EX-25.2

Form T-1 Statement of Eligibility under Trust Indenture Act of 1939 of Trustee under STERIS Irish FinCo Unlimited Company Debt Securities Indenture

Exhibit 25.2 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ? Check if an Application to Determine Eligibility of a Trustee Pursuant to Section 305(b)(2) U.S. BANK NATIONAL ASSOCIATION (Exact name of Trustee as specified in its charter) 31-0841368 I.R.S. Employer Identif

March 2, 2021 EX-23.7

Consent of Centerview Partners LLC

Exhibit 23.7 Consent of Centerview Partners LLC The Board of Directors Cantel Medical Corp. 150 Clove Road Little Falls, NJ 07424 The Board of Directors: We hereby consent to the inclusion of our opinion letter, dated January 12, 2021, to the Board of Directors of Cantel Medical Corp. (“Cantel”) as Annex B to, and reference to such opinion letter under the headings “Summary—Opinion of Cantel’s Fin

March 2, 2021 EX-15.1

LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the Registration Statement (Form S-4) and related proxy statement/prospectus of STERIS plc for the registration of 14,287,997 shares of its common stock of our reports dated August 7, 2020, November 6, 2020 and February 9, 2021 relat

March 2, 2021 EX-24.1

POWER OF ATTORNEY

Exhibit 24.1 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that each of the undersigned directors and officers of STERIS plc, an Irish public limited company (the ?Registrant?), does hereby constitute and appoint Walter M Rosebrough, Jr., Michael J. Tokich and J. Adam Zangerle, and each of them acting individually, as the true and lawful attorney-in-fact or attorneys-in-fact for each of the unders

March 2, 2021 EX-99.1

EX-99.1

Exhibit 99.1

March 2, 2021 S-4

Amendment to Agreement and Plan of Merger dated March 1, 2021 (filed as Exhibit 2.2 to the Registrant’s registration statement on Form S-4 filed with the Commission on March 2, 2021)

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 2, 2021 Registration No.

February 10, 2021 SC 13G/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 5)*

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 5)* Name of issuer: STERIS plc Title of Class of Securities: Common Stock CUSIP Number: G8473T100 Date of Event Which Requires Filing of this Statement: December 31, 2020 Check the appropriate box to designate the rule pursuant to which this Schedule is filed: ☒ Rule 13d

February 9, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 9, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

February 9, 2021 EX-10.5

Guarantor Supplement dated December 17, 2020 by KS Apollo Holdings Inc., KS Apollo LLC and Key Surgical LLC of Affiliate Guaranty dated March 5, 2019 of STERIS Corporation May 15, 2015 Note Purchase Agreements, as amended and restated, and Notes issues pursuant thereto.

EXHIBIT 10.5 GUARANTY SUPPLEMENT December 17, 2020 To the Holders of the Series A-1, A-2 and A-3, (each, as hereinafter defined) of STERIS Corporation (the “Company”) Ladies and Gentlemen: WHEREAS, in order to refinance certain debt and for general corporate purposes, the Company entered into that certain Amended and Restated Note Purchase Agreement, dated as of March 5, 2019 (as amended, amended

February 9, 2021 EX-10.4

Guarantor Supplement dated December 17, 2020 by KS Apollo Holdings Inc., KS Apollo LLC and Key Surgical LLC of Affiliate Guaranty dated March 5, 2019 of STERIS Corporation December 4, 2012 Note Purchase Agreements, as amended and restated, and Notes issues pursuant thereto.

EXHIBIT 10.4 GUARANTY SUPPLEMENT December 17, 2020 To the Holders of the Series A-1A, A-1B, A-2A, A-2B, A-3A and A-3B Notes, (each, as hereinafter defined) of STERIS Corporation (the “Company”) Ladies and Gentlemen: WHEREAS, in order to refinance certain debt and for general corporate purposes, the Company entered into that certain Amended and Restated Note Purchase Agreement, dated as of March 5,

February 9, 2021 EX-99.1

EXPLANATORY NOTE

Exhibit 99.1 EXPLANATORY NOTE STERIS plc (the "Company") is filing this exhibit to reflect changes to the presentation of the Company’s financial information as set forth in the Company's Annual Report on Form 10-K for the year ended March 31, 2020 (the "Fiscal 2020 Form 10-K"), as filed with the Securities and Exchange Commission ("SEC") on May 29, 2020, in order to give effect to a change in seg

February 9, 2021 EX-10.2

Guarantor Joinder Agreement dated December 18, 2020 among KS Apollo Holdings Inc., KS Apollo LLC, and Key Surgical LLC, pursuant to Credit Agreement in favor of JPMorgan Chase Bank, N.A., as Administrative Agent.

EXHIBIT 10.2 GUARANTOR JOINDER AGREEMENT This Guarantor Joinder Agreement (this “Agreement”) dated as of December 18, 2020 is made by each of the parties on Schedule I hereto (the “Additional Guarantors”), in favor of JPMorgan Chase Bank, N.A., as Administrative Agent (in such capacity, the “Administrative Agent”) for the Lenders under the Credit Agreement referred to below. RECITALS WHEREAS, refe

February 9, 2021 EX-10.3

Guarantor Joinder Agreement dated December 18, 2020 among KS Apollo Holdings Inc., KS Apollo LLC, and Key Surgical LLC pursuant to Term Loan Agreement in favor of JPMorgan Chase Bank, N.A., as Administrative Agent.

EXHIBIT 10.3 GUARANTOR JOINDER AGREEMENT This Guarantor Joinder Agreement (this “Agreement”) dated as of December 18, 2020 is made by each of the parties on Schedule I hereto (the “Additional Guarantors”), in favor of JPMorgan Chase Bank, N.A., as Administrative Agent (in such capacity, the “Administrative Agent”) for the Lenders under the Credit Agreement referred to below. RECITALS WHEREAS, refe

February 9, 2021 EX-15.1

Letter Re: Unaudited Interim Financial Information.

Exhibit 15.1 LETTER REGARDING UNAUDITED INTERIM FINANCIAL INFORMATION Shareholders and Board of Directors STERIS plc We are aware of the incorporation by reference in the following STERIS plc Registration Statements of our review report dated February 9, 2021 relating to the unaudited consolidated interim financial statements of STERIS plc and subsidiaries that are included in its Form 10-Q for th

February 9, 2021 10-Q

Quarterly Report - 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D. C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended December 31, 2020 or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

February 9, 2021 EX-10.6

Guarantor Supplement dated December 17, 2020 by KS Apollo Holdings Inc., KS Apollo LLC and Key Surgical LLC of Affiliate Guaranty dated March 5, 2019 of STERIS Limited January 23, 2017 Note Purchase Agreements, as amended and restated, and Notes issues pursuant thereto.

EXHIBIT 10.6 GUARANTY SUPPLEMENT December 17, 2020 To the Holders of the Series A-1, A-2, A-3, A-4, A-5, A-6 and A-7 Notes, (each, as hereinafter defined) of STERIS Limited (the “Company”) Ladies and Gentlemen: WHEREAS, in order to refinance certain debt and for general corporate purposes, the Company entered into that certain Amended and Restated Note Purchase Agreement, dated as of March 5, 2019

February 3, 2021 425

Merger Prospectus - 425

Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date: 02/03/2021 CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION This communication contains forward-looking statements within the meaning of the federal securities laws about STERIS, Cantel and the prop

February 3, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 29, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or Other Jurisdiction of Incorporation) (Commission File Number) (IR

February 3, 2021 425

Merger Prospectus - 425

Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date: 02/03/2021 TO: Cantel Employees FROM: STERIS President & CEO Subject: Leadership Succession Planning Dear Cantel Employees: It has been almost a month since we announced our intention to combine our two compa

February 3, 2021 EX-99.1

STERIS Announces Leadership Succession Plan

EX-99.1 Exhibit 99.1 STERIS Announces Leadership Succession Plan • Walt Rosebrough to step down as CEO at the upcoming Annual General Meeting • Chief Operating Officer, Dan Carestio, to succeed as President and CEO DUBLIN, IRELAND - (February 3, 2021) - STERIS plc (NYSE: STE) (“STERIS” or the “Company”) today announced that Walt Rosebrough, President and CEO, has announced his intention to step do

February 2, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 2, 2021 STERIS plc (Exact Name of Registrant as Specified in Charter) Ireland 001-38848 98-1455064 (State or other jurisdiction of incorporation or organization) (Commission

February 2, 2021 EX-99.1

STERIS Announces Financial Results for Fiscal 2021 Third Quarter

EX-99.1 2 ste12312020ex991.htm EX-99.1 Exhibit 99.1 STERIS Announces Financial Results for Fiscal 2021 Third Quarter • Third quarter revenue increases 4% as reported; 1% constant currency organic • Third quarter earnings per diluted share increase to $1.33 on a U.S. GAAP basis and $1.73 on an adjusted basis • Increased free cash flow driven by net income growth and working capital improvements DUB

January 22, 2021 EX-3

Exhibit 3

Exhibit 3 JOINT FILING AGREEMENT We, the undersigned, hereby express our agreement that the attached Schedule 13D is, and any further amendments thereto signed by each of the undersigned shall be, filed on behalf of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934.

January 22, 2021 SC 13D

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 CANTEL MEDICAL CORP. (Name of Issuer) Common Stock, $0.10 par value (Title of Class of Securities) 138098108 (CUSIP Number) J

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 CANTEL MEDICAL CORP.

January 13, 2021 425

Merger Prospectus - 425

1-877-FACTSET www.callstreet.com Total Pages: 12 Copyright © 2001-2021 FactSet CallStreet, LLC 13-Jan-2021 STERIS Plc (Ireland) (STE) JP Morgan Healthcare Conference Filed by STERIS plc Commission File No.: 001-38848 Pursuant to Rule 425 under the Securities Act of 1933, as amended Subject Company: Cantel Medical Corp. Commission File No.: 001-31337 Date: January 01/13/2021 Corrected Transcript ST

January 13, 2021 425

Merger Prospectus - 425

Corrected Transcript Total Pages: 17 12-Jan-2021STERIS Plc (Ireland) (STE)Acquisition of Cantel Medical Corp by STERIS plc Call 1-877-FACTSET www.

January 12, 2021 EX-99.4

Dear Cantel Employees:

Exhibit 99.4 Dear Cantel Employees: As you have heard from your leadership team, we have announced our intention to acquire Cantel. I know that announcements like this can cause significant stress and anxiety for the people of both companies, and it doesn’t help that we will not have many details until closing. I am writing today to do my best to ease your mind about the Company you will be joinin

January 12, 2021 EX-2.1

Agreement and Plan of Merger, dated January 12, 2021, by and among STERIS plc, Solar New US Holding Co, LLC, Crystal Merger Sub 1, LLC and Cantel Medical Corp. (filed as Exhibit 2.1 to STERIS plc Form 8-K filed January 12, 2021 (Commission File No. 001-38848) and incorporated herein by reference).

Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER by and among STERIS plc, Solar New US Holding Co, LLC, Crystal Merger Sub 1, LLC and Cantel Medical Corp. dated as of January 12, 2021 TABLE OF CONTENTS Page ARTICLE I THE MERGERS 5 Section 1.1 The Mergers 5 Section 1.2 Closing 6 Section 1.3 Effective Times 7 Section 1.4 Governing Documents 8 Section 1.5 Officers, Directors and Managers of

January 12, 2021 EX-10.1

Exhibit 2

Exhibit 10.1 EXECUTION VERSION VOTING AND SUPPORT AGREEMENT This VOTING AND SUPPORT AGREEMENT (this “Agreement”), is dated as of January 12, 2021 (the “Effective Date”), by and among STERIS plc, a company incorporated under the laws of Ireland (“Parent”), Solar New US Holding Co, LLC, a Delaware limited liability company and a wholly owned subsidiary of Parent (“US Holdco”), Crystal Merger Sub 1,

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