OSUR / OraSure Technologies, Inc. - SEC Filings, Annual Report, Proxy Statement

OraSure Technologies, Inc.
US ˙ NasdaqGS ˙ US68554V1089

Basic Stats
LEI 529900GNNJPNM4XHXQ77
CIK 1116463
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to OraSure Technologies, Inc.
SEC Filings (Chronological Order)
This page provides a complete, chronological list of SEC Filings, excluding ownership filings which we provide elsewhere.
August 6, 2025 EX-3.2

Third Amended and Restated Bylaws of OraSure Technologies, Inc. as of August 5, 2025.

EXHIBIT 3.2 THIRD AMENDED AND RESTATED BYLAWS OF ORASURE TECHNOLOGIES, INC. Effective as of August [5], 2025 ARTICLE I Name and Location SECTION 1. Name. The name of the Corporation shall be the name set forth in the Certificate of Incorporation. SECTION 2. Principal Office. The principal office of the Corporation is located at 220 East First Street, Bethlehem, Pennsylvania 18015-1360. SECTION 3.

August 6, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number

August 5, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 5, 2025 OraSure Technologi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 5, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 5, 2025 EX-99.1

OraSure Announces Second Quarter 2025 Financial Results

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Announces Second Quarter 2025 Financial Results BETHLEHEM, PA, August 5, 2025 (GLOBE NEWSWIRE) – OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in point-of-need and home diagnostic tests and sample management solution

May 27, 2025 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015

CORRESP OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 May 27, 2025 Via EDGAR Transmission Securities and Exchange Commission Division of Corporation Finance Office of Industrial Applications and Services 100 F Street, N.E. Washington, D.C. 20549 Attention: Nicholas O’Leary Re: OraSure Technologies, Inc.   Registration Statement on Form S-3 filed May 20, 2025 (File No. 333-28

May 20, 2025 S-8

As filed with the Securities and Exchange Commission on May 20, 2025

As filed with the Securities and Exchange Commission on May 20, 2025 Registration No.

May 20, 2025 S-3

As filed with the Securities and Exchange Commission on May 20, 2025.

As filed with the Securities and Exchange Commission on May 20, 2025. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ORASURE TECHNOLOGIES, INC. (Exact Name of Registrant as Specified in Its Charter) Delaware 36-4370966 (State or Other Jurisdiction of Incorporation or Organization) (IRS E

May 20, 2025 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) OraSure Technologies, Inc.

May 20, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) OraSure Technologies, Inc.

May 20, 2025 EX-4.1

Specimen Certificate representing shares of the Company’s $0.000001 par value Common Stock.

osur-sx3xex41 Exhibit 4.1 O R A S U R E T E C H N O L O G I E S , I N C . T H E C O R P O R A T I O N W I L L F U R N I S H W I T H O U T C H A R G E T O E A C H S H A R E H O L D E R W H O S O R E Q U E S T S , A S U M M A R Y O F T H E P O W E R S , D E S I G N A T I O N S , P R E F E R E N C E S A N D R E L A T I V E , P A R T I C I P A T I N G , O P T I O N A L O R O T H E R S P E C I A L R I

May 20, 2025 EX-4.4 1

Form of Indenture to be entered into between the Company and a Trustee acceptable to the Company.

Exhibit 4.4.1 FORM OF INDENTURE ORASURE TECHNOLOGIES, INC., as Issuer, and [ ], as Trustee Indenture Dated as of [ ] Providing for the Issuance Of Debt Securities ORASURE TECHNOLOGIES, INC. Reconciliation and tie between Trust Indenture Act of 1939 and indenture, dated as of [ ] Trust Indenture Act Section Indenture Section §310 (a)(1) 6.07 (a)(2) 6.07 (b) 6.09 §311 (a) 7.06 (b) 7.06 §312 (a) 7.01

May 14, 2025 EX-10.1

Amended and Restated OraSure Technologies, Inc. 2000 Stock Award Plan.

ORASURE TECHNOLOGIES, INC. STOCK AWARD PLAN ARTICLE 1 ESTABLISHMENT AND PURPOSE (Amended and Restated Effective as of March 24, 2025) Establishment. Epitope, Inc. established this Plan as the Epitope, Inc. 2000 Stock Award Plan, effective as of February 15, 2000, and the Plan was approved by shareholders of Epitope, Inc. at the 2000 annual shareholders meeting. Effective September 29, 2000, in con

May 14, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 14, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 9, 2025 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No.2) CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No.2) CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorp

May 9, 2025 EX-99.1

ORASURE TECHNOLOGIES, INC. UNAUDITED PROFORMA CONDENSED COMBINED FINANCIAL INFORMATION

Exhibit 99.1 ORASURE TECHNOLOGIES, INC. UNAUDITED PROFORMA CONDENSED COMBINED FINANCIAL INFORMATION On December 19, 2024, the OraSure Technologies, Inc. (the “Company”) acquired Sherlock Biosciences, Inc. (“Sherlock”), pursuant to the terms of a merger agreement (the “Merger”). In connection with the Merger, Sherlock merged with and into Project Watson Merger Sub, Inc., a wholly-owned subsidiary o

May 9, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 8, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission File

May 7, 2025 EX-99.1

OraSure Announces First Quarter 2025 Financial Results

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Announces First Quarter 2025 Financial Results BETHLEHEM, PA, May 7, 2025 (GLOBE NEWSWIRE) – OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in point-of-need and home diagnostic tests and sample management solutions, t

May 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 7, 2025 OraSure Technologies,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 7, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission File

May 7, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number

May 7, 2025 EX-18.1

Preferability Letter

Exhibit 18.1 May 7, 2025 Board of Directors OraSure Technologies, Inc. 220 E 1st St. Bethlehem, PA18015 Dear Directors: We are providing this letter solely for inclusion as an exhibit to OraSure Technologies Inc. (the “Company”") Form 10-Q filing pursuant to Item 601 of Regulation S-K. As stated in Note 1 to the unaudited consolidated financial statements included in the Company’s Quarterly Report

April 4, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defi

April 4, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

March 24, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 24, 2025 OraSure Technologi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 24, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

March 24, 2025 EX-99.1

OraSure Announces $40 Million Stock Repurchase Program

EXHIBIT 99.1 Investor Contact: Jason Plagman VP, Investor Relations [email protected] Media Contact: Amy Koch Director, Corporate Communications [email protected] OraSure Announces $40 Million Stock Repurchase Program BETHLEHEM, PA, March 24, 2025 (GLOBE NEWSWIRE) - OraSure Technologies, Inc. (the “Company”) (NASDAQ: OSUR), a leader in point-of-need and home diagnostic tests and sample mana

March 7, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File No. 001-16537

March 7, 2025 EX-24.1

Powers of Attorney.

Exhibit 24.1 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that the undersigned constitutes and appoints Michele Anthony and Stefano Taucer, and each of them, her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of Or

March 7, 2025 EX-19.1

Insider Trading Policy

Exhibit 19.1 ORASURE TECHNOLOGIES, INC. POLICY STATEMENT ON DEALING WITH COMPANY INFORMATION, INCLUDING INSIDE INFORMATION AND INSIDER SECURITIES TRADING (Effective as of May 2, 2023) In the course of conducting the business of OraSure Technologies, Inc. (the “Company”) and its subsidiaries, you may at times have information about the Company or its subsidiaries or another entity that generally is

March 7, 2025 EX-99.2

ORASURE TECHNOLOGIES, INC. UNAUDITED PROFORMA CONDENSED COMBINED FINANCIAL INFORMATION

Exhibit 99.2 ORASURE TECHNOLOGIES, INC. UNAUDITED PROFORMA CONDENSED COMBINED FINANCIAL INFORMATION On December 19, 2024, the OraSure Technologies, Inc. (the “Company”) acquired Sherlock Biosciences, Inc. (“Sherlock”), pursuant to the terms of a merger agreement (the “Merger”). In connection with the Merger, Sherlock merged with and into Project Watson Merger Sub, Inc., a wholly-owned subsidiary o

March 7, 2025 EX-99.1

Sherlock Biosciences, Inc. and Subsidiaries Consolidated Financial Statements For the Nine Months Ended September 30, 2024 and the Year Ended December 31, 2023 With Independent Auditors’ Report SHERLOCK BIOSCIENCES, INC. AND SUBSIDIARIES CONSOLIDATED

Sherlock Biosciences, Inc. and Subsidiaries Consolidated Financial Statements For the Nine Months Ended September 30, 2024 and the Year Ended December 31, 2023 With Independent Auditors’ Report SHERLOCK BIOSCIENCES, INC. AND SUBSIDIARIES CONSOLIDATED FINANCIAL STATEMENTS For the Nine Months Ended September 30, 2024 and the Year Ended December 31, 2023 TABLE OF CONTENTS Page Independent Auditors’ R

March 7, 2025 8-K/A

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No.1) CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorp

March 7, 2025 EX-2.1

Agreement and Plan of Merger, dated December 19, 2024 by and among OraSure Technologies, Inc., Project Watson Merger Sub, Inc., Sherlock Biosciences, Inc. and Mr. Paul Meister, solely in his capacity as representative of the securityholders of Sherlock Biosciences, Inc.

Exhibit 2.1 [***] Certain information in this document has been excluded pursuant to Regulation S-K, Item 601(b)(10). Such excluded information is not material and the registrant customarily and actually treats as private and confidential. Agreement and Plan of Merger by and among OraSure Technologies, Inc., Project Watson Merger Sub, Inc., Sherlock Biosciences, Inc. and Mr. Paul Meister, as the S

March 7, 2025 EX-21.2

Subsidiaries of the Company

Exhibit 21.1 Subsidiaries of the Registrant Subsidiary Place of Incorporation/ Organization DNA Genotek Inc. Canada Sherlock Biosciences, Inc Delaware Sherlock Securities Corporation Massachusetts 221B Foundation Delaware Sense Biodetection Limited England and Wales Sense Biodetection Inc Delaware

February 25, 2025 EX-99.1

OraSure Reports Fourth Quarter 2024 Financial Results

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Fourth Quarter 2024 Financial Results BETHLEHEM, PA, February 25, 2025 (GLOBE NEWSWIRE) – OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in point-of-need and home diagnostic tests and sample management solutio

February 25, 2025 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): February 25, 2025 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

December 26, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

December 19, 2024 EX-99.2

OraSure Technologies Acquires Sherlock Biosciences

EXHIBIT 99.2 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Technologies Acquires Sherlock Biosciences BETHLEHEM, PA, December 19, 2024 (GLOBE NEWSWIRE) - OraSure Technologies, Inc. (“OTI”) (NASDAQ: OSUR), a leader in point-of-need and home diagnostic tests and sample management so

December 19, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2024 OraSure Technol

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 19, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

December 19, 2024 EX-99.1

OraSure Technologies ACQUISITION OF SHERLOCK BIOSCIENCES DECEMBER 19, 2024 EXHIBIT 99.1 © 2024 OraSure Technologies, Inc. 2 This presentation contains certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform

exhibit991projwatsoninv OraSure Technologies ACQUISITION OF SHERLOCK BIOSCIENCES DECEMBER 19, 2024 EXHIBIT 99.

November 6, 2024 EX-99.1

OraSure Reports Q3 ’24 Revenue of $39.9 Million Q3 GAAP EPS of $(0.06); Q3 Non-GAAP EPS of $(0.01) OraQuick® HCV Self-test receives initial orders following receipt of WHO pre-qualification status Expanding Sample Management applications into blood p

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q3 ’24 Revenue of $39.9 Million Q3 GAAP EPS of $(0.06); Q3 Non-GAAP EPS of $(0.01) OraQuick® HCV Self-test receives initial orders following receipt of WHO pre-qualification status Expanding Sample Management appli

November 6, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 6, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 6, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Nu

October 31, 2024 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 October 31, 2024

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 October 31, 2024 VIA EDGAR Submission U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Irene Paik, James Lopez Re: ORASURE TECHNOLOGIES INC Form 8-K Filed April 12, 2024 File No. 001-16537 Dear Ladies and Gentlemen: OraSure Technologies

October 4, 2024 SC 13G

OSUR / OraSure Technologies, Inc. / Neuberger Berman Group LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 ORASURE TECHNOLOGIES INC (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is file

September 9, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 5, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

August 12, 2024 S-8

As filed with the Securities and Exchange Commission on August 12, 2024

As filed with the Securities and Exchange Commission on August 12, 2024 Registration No.

August 12, 2024 EX-FILING FEES

Filing Fee Table.

EX-FILING FEES 2 osur-formsx8ex107amended.htm EX-FILING FEES ACTIVE/130835542.2 Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) OraSure Technologies, Inc. (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered (1)(2) Proposed Maximum Offering Price Per U

August 6, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 6, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 6, 2024 EX-99.1

OraSure Reports Q2 ’24 Revenue of $54.3 Million Q2 GAAP EPS of $(0.01); Q2 Non-GAAP EPS of $0.07 OraQuick® HCV Self-test is the first globally to earn WHO pre-qualification Strong momentum with Syphilis Health CheckTM launch Expanding Sample Manageme

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q2 ’24 Revenue of $54.3 Million Q2 GAAP EPS of $(0.01); Q2 Non-GAAP EPS of $0.07 OraQuick® HCV Self-test is the first globally to earn WHO pre-qualification Strong momentum with Syphilis Health CheckTM launch Expan

August 6, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number

June 10, 2024 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 June 10, 2024         VIA EDGAR Submission U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Irene Paik, James Lopez Re: ORASURE TECHNOLOGIES INC   Form 8-K   Filed April 12, 2024   File No. 001-16537 Dear Ladies and Gentlemen: OraSure T

May 17, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 14, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 17, 2024 EX-10.1

Amended and Restated OraSure Technologies, Inc. 2000 Stock Award Plan.

Exhibit 10.1 ORASURE TECHNOLOGIES, Inc. Stock award plan ARTICLE 1 ESTABLISHMENT AND PURPOSES (Amended and Restated Effective as of March 25, 2024) Establishment. Epitope, Inc. established this Plan as the Epitope, Inc. 2000 Stock Award Plan, effective as of February 15, 2000, and the Plan was approved by shareholders of Epitope, Inc. at the 2000 annual shareholders meeting. Effective September 29

May 17, 2024 EX-3.1

Certificate of Amendment to Certificate of Incorporation dated May 16, 2024 (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K as filed on May 17, 2024)

EXHIBIT 3.1 CERTIFICATE OF AMENDMENT TO THE CERTIFICATE OF INCORPORATION OF ORASURE TECHNOLOGIES, INC. OraSure Technologies, Inc. (the “Corporation”), a corporation organized and existing under the provisions of the General Corporation Law of the State of Delaware (the “General Corporation Law”), hereby certifies that: 1. The name of this corporation is OraSure Technologies, Inc. The Corporation’s

May 9, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number

May 8, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 8, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission File

May 8, 2024 EX-99.1

OraSure Reports Q1 ’24 Revenue of $54.1 Million Q1 GAAP EPS of $(0.05); Q1 Non-GAAP EPS of $0.04 Restructuring initiatives expected to result in $15 million of annualized expense reductions once fully implemented and position OraSure to achieve cash

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q1 ’24 Revenue of $54.1 Million Q1 GAAP EPS of $(0.05); Q1 Non-GAAP EPS of $0.04 Restructuring initiatives expected to result in $15 million of annualized expense reductions once fully implemented and position OraS

May 1, 2024 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 May 1, 2024

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 May 1, 2024 VIA EDGAR Submission U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Jeanne Baker, Al Pavot Re: ORASURE TECHNOLOGIES INC Form 10-K filed March 11, 2024 Item 2.02 Form 8-K filed February 27, 2024 Response filed April 10, 202

April 12, 2024 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): April 10, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

April 10, 2024 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015

OraSure Technologies, Inc. 220 East First Street Bethlehem, PA 18015 April 10, 2024 VIA EDGAR Submission U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attn: Jeanne Baker, Al Pavot Re: ORASURE TECHNOLOGIES INC Form 10-K filed March 11, 2024 Item 2.02 Form 8-K filed February 27, 2024 File No. 001-16537 Dear L

April 4, 2024 DEFA14A

DEFA14A

Smartphone users Point your camera here and vote without entering a control number For complete information and to vote, visit www.

April 4, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Definitive Proxy State

April 3, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Defi

March 22, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: x Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) o Defi

March 11, 2024 EX-24

Powers of Attorney.

Exhibit 24.1 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that the undersigned constitutes and appoints Michele Anthony and Stefano Taucer, and each of them, her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of Or

March 11, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 or o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File No. 001-16537

March 11, 2024 EX-97.1

OraSure Technologies Inc. Compensation Recovery Policy

EXHIBIT 97.1 ORASURE TECHNOLOGIES, INC. COMPENSATION RECOVERY POLICY Adopted as of November 14, 2023 OraSure Technologies, Inc., a Delaware corporation (the “Company”), has adopted a Compensation Recovery Policy (this “Policy”) as described below. 1. Overview The Policy sets forth the circumstances and procedures under which the Company shall recover Erroneously Awarded Compensation from Covered P

February 27, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): February 27, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

February 27, 2024 EX-99.1

OraSure Reports Q4 ‘23 Revenue of $75.9 Million Q4 GAAP EPS of $0.27; Q4 Non-GAAP EPS of $0.22 Grew cash balance to $290.4 million as of December 31, 2023 Enters U.S. Syphilis testing market via strategic distribution agreement with Diagnostics Direc

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q4 ‘23 Revenue of $75.9 Million Q4 GAAP EPS of $0.27; Q4 Non-GAAP EPS of $0.22 Grew cash balance to $290.4 million as of December 31, 2023 Enters U.S. Syphilis testing market via strategic distribution agreement wi

February 13, 2024 SC 13G/A

OSUR / OraSure Technologies, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01624-orasuretechnologiesi.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 7)* Name of issuer: OraSure Technologies Inc Title of Class of Securities: Common Stock CUSIP Number: 68554V108 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box t

February 9, 2024 SC 13G

OSUR / OraSure Technologies, Inc. / DIMENSIONAL FUND ADVISORS LP - SEC SCHEDULE 13G Passive Investment

SC 13G 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* OraSure Technologies Inc (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 29, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box t

January 4, 2024 EX-99.1

OraSure Technologies, Inc. STRATEGIC PARTNERSHIP & INVESTMENT IN SAPPHIROS JANUARY 4, 2024 Exhibit 99.1 © 2024 OraSure Technologies, Inc. 2 This presentation contains certain “forward-looking statements” within the meaning of the Private Securities L

exhibit991sapphireinves OraSure Technologies, Inc. STRATEGIC PARTNERSHIP & INVESTMENT IN SAPPHIROS JANUARY 4, 2024 Exhibit 99.1 © 2024 OraSure Technologies, Inc. 2 This presentation contains certain “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including with respect to products, product development and manufacturing activities, the invest

January 4, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): January 4, 2024 OraSure Technolog

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): January 4, 2024 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

January 4, 2024 EX-99.2

OraSure Technologies, Inc. Secures Strategic Distribution Rights and Invests in Sapphiros, a Next-Generation Consumer Diagnostics Company The relationship expands OraSure’s innovation pipeline with access to a broad portfolio of key Sapphiros product

EXHIBIT 99.2 Investor Contact: Jason Plagman VP, Investor Relations [email protected] Media Contact: Amy Koch Director, Corporate Communications [email protected] OraSure Technologies, Inc. Secures Strategic Distribution Rights and Invests in Sapphiros, a Next-Generation Consumer Diagnostics Company The relationship expands OraSure’s innovation pipeline with access to a broad portfolio of k

December 5, 2023 8-K

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 29, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

December 5, 2023 EX-16.1

LLP to the Securities and Exchange Commission, dated December 5, 2023.

EXHIBIT 16.1 December 5, 2023 Securities and Exchange Commission Washington, D.C. 20549 Ladies and Gentlemen: We are currently principal accountants for OraSure Technologies, Inc. (“the Company”) and, under the date of March 3, 2023, we reported on the consolidated financial statements of the Company as of and for the three year period ended December 31, 2022, and the effectiveness of internal con

November 8, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Nu

November 7, 2023 EX-99.1

OraSure Reports Q3 ‘23 Revenue of $89.2 Million; Core Revenue Grows 7% Year-over-Year Q3 GAAP EPS of $0.15; Q3 Non-GAAP EPS of $0.27 Grew cash balance to $224.9 million as of September 30, 2023

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q3 ‘23 Revenue of $89.2 Million; Core Revenue Grows 7% Year-over-Year Q3 GAAP EPS of $0.15; Q3 Non-GAAP EPS of $0.27 Grew cash balance to $224.9 million as of September 30, 2023 BETHLEHEM, PA, November 7, 2023 (GLO

November 7, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 7, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

August 4, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023. OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number

August 4, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) OraSure Technologies, Inc.

August 4, 2023 S-8

As filed with the Securities and Exchange Commission on August 4, 2023

As filed with the Securities and Exchange Commission on August 4, 2023 Registration No.

August 3, 2023 EX-99.1

OraSure Reports Q2 ‘23 Revenue of $85.4 Million; Core Revenue Grows 3% Year-over-Year InteliSwab® test revenue of $47.5 million in Q2 Q2 Core revenue of $37.9 million grew 4% sequentially and 3% year-over-year Q2 GAAP EPS of $(0.07); Q2 Non-GAAP EPS

EXHIBIT 99.1 Investor Contact: Media Contact: Jason Plagman Amy Koch VP, Investor Relations Director, Corporate Communications [email protected] [email protected] OraSure Reports Q2 ‘23 Revenue of $85.4 Million; Core Revenue Grows 3% Year-over-Year InteliSwab® test revenue of $47.5 million in Q2 Q2 Core revenue of $37.9 million grew 4% sequentially and 3% year-over-year Q2 GAAP EPS of $(0.0

August 3, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 3, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 2, 2023 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 16, 2023 OraSure Technologi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 16, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

July 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): July 19, 2023 OraSure Technologie

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): July 19, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fi

May 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 16, 2023 OraSure Technologies

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 16, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 16, 2023 EX-10.1

Amended and Restated OraSure Technologies, Inc. 2000 Stock Award Plan.

EXHIBIT 10.1 ORASURE TECHNOLOGIES, INC. STOCK AWARD PLAN ARTICLE 1 ESTABLISHMENT AND PURPOSE (Amended and Restated Effective as of March 31, 2023) Establishment. Epitope, Inc. established this Plan as the Epitope, Inc. 2000 Stock Award Plan, effective as of February 15, 2000, and the Plan was approved by shareholders of Epitope, Inc. at the 2000 annual shareholders meeting. Effective September 29,

May 12, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 9, 2023 OraSure Technologies,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 9, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission File

May 10, 2023 10-Q

ou UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

ou UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023. OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORAS

May 10, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 10, 2023 OraSure Technologies

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 10, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 10, 2023 EX-3

Second Amended and Restated Bylaws of OraSure Technologies, Inc., as of May 9, 2023 (incorporated by reference to Exhibit 3.1 to the Registrant’s Quarterly Report on Form 10-Q as filed on May 10, 2023).

EXHIBIT 3.1 SECOND AMENDED AND RESTATED BYLAWS OF ORASURE TECHNOLOGIES, INC. Effective as of May 9, 2023 ARTICLE I Name and Location SECTION 1. Name. The name of the Corporation shall be the name set forth in the Certificate of Incorporation. SECTION 2. Principal Office. The principal office of the Corporation is located at 220 East First Street, Bethlehem, Pennsylvania 18015-1360. SECTION 3. Addi

May 10, 2023 EX-99

OraSure Reports 1Q23 Record Revenue of $155.0 Million; Announces New Collaborations as Company Increasingly Focuses on Core Growth InteliSwab® test revenue of $118.3 million in Q1, up 33% sequentially; Company delivers cost savings and begins to tape

EXHIBIT 99.1 Investor Contact: Scott Gleason SVP Investor Relations & Corp. Communications (484) 425-0588 [email protected] Media Contact: Amy Koch Director, Corporate Communications (484) 523-1815 [email protected] OraSure Reports 1Q23 Record Revenue of $155.0 Million; Announces New Collaborations as Company Increasingly Focuses on Core Growth InteliSwab® test revenue of $118.3 million in Q1,

April 27, 2023 PX14A6G

OraSure Technologies Exempt Solicitation

PX14A6G 1 x425231px14a6g.htm OraSure Technologies Exempt Solicitation Notice of Exempt Solicitation (Voluntary Submission) Pursuant to Rule 14a-103 Name of the Registrant: OraSure Technologies, Inc. Name of persons relying on exemption: Nia Impact Capital Address of persons relying on exemption: 4900 Shattuck Ave #3648, Oakland, CA 94609 Written materials are submitted pursuant to Rule 14a-6(g)(1)

April 14, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

April 14, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

March 27, 2023 S-8

As filed with the Securities and Exchange Commission on March 27, 2023

S-8 As filed with the Securities and Exchange Commission on March 27, 2023 Registration No.

March 27, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) OraSure Technologies, Inc.

March 27, 2023 EX-99.2

Form of Inducement Restricted Unit Award Agreement.

EX-99.2 Exhibit 99.2 RESTRICTED UNIT INDUCEMENT AWARD AGREEMENT (Performance Vested) (Executive Officers –Employment Agreements) This Restricted Unit Inducement Award Agreement (“Agreement”) is entered into as of [DATE] between OraSure Technologies, Inc,, a Delaware corporation (“OraSure” or the “Company”), and NAME (“Participant”). OraSure hereby awards to the Participant the number of restricted

March 27, 2023 EX-99.1

Form of Inducement Restricted Share Award Agreement.

EX-99.1 Exhibit 99.1 RESTRICTED SHARE INDUCEMENT AWARD AGREEMENT This Restricted Share Inducement Award Agreement (“Agreement”) is entered into as of [DATE] between OraSure Technologies, Inc., a Delaware corporation (“OraSure” or the “Company”), and [Recipient] (“Participant”). OraSure hereby awards to the Participant the number of restricted shares of OraSure common stock set forth in Section 1.2

March 27, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) OraSure Technologies, Inc.

March 27, 2023 S-8

Registration Statement No. 333-270861 filed on March 27, 2023

S-8 As filed with the Securities and Exchange Commission on March 27, 2023 Registration No.

March 16, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 15, 2023 OraSure Technologi

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 15, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

March 3, 2023 10-K

Annual Report on Form 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ Annual report pursuant to Section 13 or 15(d) of the Securities Exchange ACT OF 1934 For the fiscal year ended December 31, 2022 or ☐ Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File No. 001-16537 ORASURE TECHNOLOGI

March 3, 2023 EX-24

Powers of Attorney.

Exhibit 24 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that the undersigned constitutes and appoints Michele Anthony and Stefano Taucer and each of them, her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the Annual Report on Form 10-K of OraSure Technologies, Inc.

March 3, 2023 EX-10

Amendment No. 2 to Employment Agreement, dated as of November 7, 2022, between Kathleen G. Weber, DNA Genotek, Inc. and OraSure Technologies, Inc.

EXHIBIT 10.5 AMENDMENT NO. 2 TO EMPLOYMENT AGREEMENT This Amendment No. 2 to Employment Agreement is entered into on November 7, 2022 (this “Amendment”), by and among Kathleen G. Weber, DNA Genotek, Inc. and OraSure Technologies, Inc. WHEREAS, the parties have entered into an Employment Agreement, dated as of January 1, 2019, and amended that agreement on December 20, 2021 (as amended, the “Employ

February 14, 2023 EX-99

OraSure Reports 4Q22 Record Revenue of $123.1 Million Growing 94% Year-Over-Year; Positions for Longer-Term Growth and Profitability InteliSwab® revenue of $88.9 million in Q4, up 12% sequentially; wins two new federal government contracts extending

EXHIBIT 99.1 Investor Contact: Scott Gleason SVP investor Relations & Corporate Communications (484) 425-0588 [email protected] Media Contact: Amy Koch Sr. Manager Corporate Communications (484) 523-1815 [email protected] OraSure Reports 4Q22 Record Revenue of $123.1 Million Growing 94% Year-Over-Year; Positions for Longer-Term Growth and Profitability InteliSwab® revenue of $88.9 million in Q4

February 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): February 14, 2023 OraSure Technol

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): February 14, 2023 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

February 9, 2023 SC 13G/A

OSUR / OraSure Technologies, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01592-orasuretechnologiesi.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 6)* Name of issuer: OraSure Technologies Inc. Title of Class of Securities: Common Stock CUSIP Number: 68554V108 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box

February 7, 2023 SC 13G/A

OSUR / OraSure Technologies, Inc. / MANAGED ACCOUNT ADVISORS LLC Passive Investment

SC 13G/A 1 doc1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 02)* ORASURE TECHNOLOGIES, INC. (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the r

February 2, 2023 SC 13G

OSUR / OraSure Technologies, Inc. / Camber Capital Management LP - PRIMARY DOCUMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 ORASURE TECHNOLOGIES, INC (Name of Issuer) Common Stock, $0.000001 par value (Title of Class of Securities) 68554V108 (CUSIP Number) February 02, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

February 2, 2023 EX-1

JOINT FILING AGREEMENT

EXHIBIT 1 JOINT FILING AGREEMENT This Joint Filing Agreement dated February 2, 2023 is by and between Camber Capital Management LP, a Delaware limited partnership, and Stephen DuBois, an individual (the foregoing are collectively referred to herein as the "Filers").

November 22, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 22, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

November 14, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 7, 2022 OraSure Technolo

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 7, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 8, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORA

November 8, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 8, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 8, 2022 EX-99.1

OraSure Reports 3Q22 Record Revenue of $116.5 Million Growing 116% Year-Over-Year InteliSwab® revenue of $79.6 million in Q3, up 85% sequentially; Company continues to expand test production capacity Company wins new contracts for COVID-19 testing al

EXHIBIT 99.1 Investor Contact: Scott Gleason SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Reports 3Q22 Record Revenue of $116.5 Million Growing 116% Year-Over-Year InteliSwab? revenue of $79.6 million in Q3, up 85% sequentially; Company continues to expand test produc

August 12, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 8, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 12, 2022 EX-10.1

Employment Agreement dated August 8, 2022, between OraSure Technologies, Inc. and Kenneth J. McGrath is incorporated by reference to Exhibit 10.1 to the Company's Current Report on Form 8-K filed on August 12, 2022.*

EXHIBIT 10.1 EMPLOYMENT AGREEMENT This Employment Agreement (this ?Agreement?) is entered into on August 8, 2022 between KEN MCGRATH (?Employee?) and ORASURE TECHNOLOGIES, INC. (?OraSure? or the ?Company?). WHEREAS, the parties wish to set forth the terms of their relationship and to enter into this Agreement and a confidentiality agreement of even date herewith (the ?Confidentiality Agreement?).

August 9, 2022 EX-99.1

OraSure Reports 2Q22 Record Revenue of $80.2 Million Growing 39% Year-Over-Year InteliSwab® revenue of $43.1 million in Q2, up 95% sequentially with significant scaling in production InteliSwab® gross margins improve sequentially by over 2,000 basis

EXHIBIT 99.1 Investor Contact: Scott Gleason SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Reports 2Q22 Record Revenue of $80.2 Million Growing 39% Year-Over-Year InteliSwab? revenue of $43.1 million in Q2, up 95% sequentially with significant scaling in production Int

August 9, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 9, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

August 9, 2022 EX-99.2

2Q22 Financial Results – Record Revenue and Improved Profitability FINANCIAL METRIC 2Q22 RESULTS 1Q22 RESULTS 2Q21 RESULTS SEQUENTIAL GROWTH RATE YEAR-OVER-YEAR GROWTH RATE Quarterly Revenue $80.2 million $67.7 million $57.6 million 18% 39% GAAP EPS

OraSure 2Q22 Earnings August 9, 2022 EXHIBIT 99.2 Required Disclosures This press release contains certain forward-looking statements, including with respect to products, product development activities, regulatory submissions and authorizations, revenue growth, cost savings, cash flow, increasing margins and other matters. Forward-looking statements are not guarantees of future performance or resu

July 15, 2022 8-K/A

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A Amendment No. 1 CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 20, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporatio

June 9, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): June 3, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 26, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 20, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 26, 2022 EX-10.1

Employment Agreement, dated as of May 20, 2022, between OraSure Technologies, Inc. and Carrie Eglinton-Manner is incorporated by reference to exhibit 10.1 to the company's Current Report on Form 8-K filed on May 26, 2022.

Exhibit 10.1 EMPLOYMENT AGREEMENT This Employment Agreement (this ?Agreement?) is entered into on May 20, 2022 between Carrie Eglinton Manner (?Employee?) and OraSure Technologies, Inc. (?OraSure? or the ?Company?). WHEREAS, the parties wish to set forth the terms of their relationship and to enter into this Agreement and a confidentiality agreement of even date herewith (the ?Confidentiality Agre

May 26, 2022 EX-99.1

Carrie Eglinton Manner Appointed Chief Executive Officer of OraSure

Exhibit 99.1 Carrie Eglinton Manner Appointed Chief Executive Officer of OraSure May 23, 2022 Company Concludes Strategic Alternative Process Given Market Conditions and its Belief in its Ability to Build on Recent Operational Success BETHLEHEM, Pa., May 23, 2022 (GLOBE NEWSWIRE) ? OraSure Technologies, Inc. (NASDAQ: OSUR), a global leader in point-of-care and home diagnostic testing and sample co

May 20, 2022 S-3/A

As filed with the Securities and Exchange Commission on May 19, 2022

As filed with the Securities and Exchange Commission on May 19, 2022 Registration No.

May 18, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 17, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 18, 2022 EX-10.1

Amended and Restated OraSure Technologies, Inc. 2000 Stock Award Plan

EXHIBIT 10.1 ORASURE TECHNOLOGIES, INC. STOCK AWARD PLAN ARTICLE 1 ESTABLISHMENT AND PURPOSE (Amended and Restated Effective as of April 1, 2022) Establishment. Epitope, Inc. established this Plan as the Epitope, Inc. 2000 Stock Award Plan, effective as of February 15, 2000, and the Plan was approved by shareholders of Epitope, Inc. at the 2000 annual shareholders meeting. Effective September 29,

May 18, 2022 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 18, 2022

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 18, 2022 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street NE Washington, D.C. 20549 Attn: Michael Davis and Celeste Murphy Re: OraSure Technologies, Inc. Registration Statement on Form S-3 Filed February 10, 2022 (File No. 333-262633) Lad

May 18, 2022 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 18, 2022

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 18, 2022 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street NE Washington, D.C. 20549 Attn: Michael Davis and Celeste Murphy Re: OraSure Technologies, Inc. Registration Statement on Form S-3 Filed February 10, 2022 (File No. 333-262633) Lad

May 13, 2022 CORRESP

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 13, 2022

OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 May 13, 2022 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street NE Washington, D.C. 20549 Attn: Michael Davis and Celeste Murphy Re: OraSure Technologies, Inc. Registration Statement on Form S-3 Filed February 10, 2022 (File No. 333-262633) Lad

May 10, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 10, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 10, 2022 EX-99.2

1Q22 Financial Results FINANCIAL METRIC 1Q22 RESULTS 1Q21 RESULTS YEAR-OVER-YEAR GROWTH RATE Quarterly Revenue $67.7 million $58.6 million 16% Diagnostics Revenue $38.3 million $14.5 million 163% Diagnostics Revenue W/O COVID-19 Products $16.2 millio

OraSure 1Q22 Earnings May 10, 2022 EXHIBIT 99.2 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to products, product development activities, regulatory submissions and authorizations and other matters. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause

May 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

May 10, 2022 EX-99.1

OraSure Reports 1Q22 Record Revenue of $67.7 Million; +16% Year-Over-Year With 21% Growth in Non-COVID Revenue InteliSwab® revenue of $22.1 million in Q1, up 50% sequentially with significant scaling in production Non-COVID molecular kits increase 42

EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO, SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Reports 1Q22 Record Revenue of $67.7 Million; +16% Year-Over-Year With 21% Growth in Non-COVID Revenue InteliSwab? revenue of $22.1 million in Q1, up 50% sequentiall

April 7, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEFA14A 1 d349071ddefa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as

April 7, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 d330681ddef14a.htm DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ PreliminaryProxy Statement ☐ Confidential,for Use of the Commi

March 23, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 20, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

March 23, 2022 EX-10.1

Employment Agreement, dated as of March 21, 2022, between OraSure Technologies, Inc. and Nancy J. Gagliano, M.D., M.B.A

Exhibit 10.1 ORASURE TECHNOLOGIES, INC. 220 East First Street Bethlehem, PA USA 18015 March 21, 2022 Via Email Nancy J. Gagliano, M.D. Dear Nancy: On behalf of OraSure Technologies, Inc. (the ?Company?), this letter sets forth the terms of your employment as the Interim Chief Executive Officer of the Company (the ?Interim CEO?). 1. Period of Service: Your employment as Interim CEO will commence on

March 1, 2022 EX-10.12

Employment Agreement, dated as of November 29, 2021, between OraSure Technologies, Inc. and Agnieszka M. Gallagher.*

EXHIBIT 10.12 EMPLOYMENT AGREEMENT This Employment Agreement (this ?Agreement?) is entered into as of November 29, 2021 (the ?Effective Date?), between Agnieszka M. Gallagher (?Employee?) and OraSure Technologies, Inc. (?OraSure? or the ?Company?). WHEREAS, the parties wish to set forth the terms of their relationship and to enter into this Agreement and a confidentiality agreement of even date he

March 1, 2022 EX-10.13

Severance Letter Agreement, dated August 25, 2021, between OraSure Technologies, Inc. and Michele M. Miller is incorporated by reference to Exhibit 10.13 to the Company's Annual Report on Form 10-K for the year ended December 31, 2021.*

EXHIBIT 10.13 August 25, 2021 Ms. Michele M. Miller Vice President, Finance and Controller Re: Severance Benefit Dear Michele: As a valued employee of OraSure Technologies, Inc. (the ?Company?), the Company would like to provide you with certain compensation in the event that your employment is terminated by the Company without Cause (as defined below) or by you for Good Reason (as defined below),

March 1, 2022 EX-10.10

Amendment No. 1 to Employment Agreement, dated as of December 20, 2021, between Kathleen G. Weber, DNA Genotek, Inc. and OraSure Technologies, Inc. is incorporated by reference to exhibit 10.10 to the Company's Annual Report on form 10-K for the year ended December 31, 2021*

EXHIBIT 10.10 AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT This Amendment No. 1 to Employment Agreement entered into as of December 20, 2021 (this ?Amendment?), by and among Kathleen G. Weber, DNA Genotek, Inc. and OraSure Technologies, Inc. WHEREAS, the parties have previously entered into an Employment Agreement, dated as of January 1, 2019 (the ?Employment Agreement?), and desire to amend the Employ

March 1, 2022 EX-10.30

Industrial Lease between Core5 at Laughman Farms Phase 1, LLC as Landlord and OraSure Technologies, Inc. as Tenant, dated January 3, 2022 is incorporated by reference to Exhibit 10.30 to the Company's Annual Report on Form 10-K for the year ended December 31, 2021.

Exhibit 10.30 INDUSTRIAL LEASE BETWEEN Core5 at Laughman Farms Phase 1, LLC AS LANDLORD AND OraSure Technologies, Inc. AS TENANT 9747900?4 LEASE INDEX Section Subject 1 Basic Lease Provisions 2 Premises 3 Term 4 Base Rent 5 Security Deposit 6 Operating Expenses and Additional Rent 7 Utilities 8 Maintenance and Repairs 9 Use of Premises 10 Insurance 11 Indemnity 12 Tenant's Fixtures 13 Signs 14 Gov

March 1, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? Annual report pursuant to Section 13 or 15(d) of the Securities Exchange ACT OF 1934 For the fiscal year ended December 31, 2021 or ? Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File No. 001-16537 ORASURE TECHNOLOGI

March 1, 2022 EX-10.20

Form of Restricted Unit Award Agreement (Executive Officers-Employment Agreements) for 2021 awards is incorporated by reference to Exhibit 10.20 to the Company's Annual Report on Form 10-K for the year ended December 31, 2021.*

EXHIBIT 10.20 RESTRICTED UNIT AWARD AGREEMENT (Performance-Vested) (OSUR Executives ?Employment Agreements) This Restricted Unit Award Agreement ("Agreement") is entered into as of February 1, 2021 between OraSure Technologies, Inc., a Delaware corporation ("OraSure" or the ?Company?), and NAME ("Participant"). The OraSure Technologies, Inc. Stock Award Plan (the "Plan") is administered by the Com

March 1, 2022 EX-24

Powers of Attorney.

EX-24 8 osur-ex24.htm EX-24 Exhibit 24 POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints Michele Miller and Agnieszka M. Gallagher, and each of them, his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign

February 23, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): February 23, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

February 23, 2022 EX-99.1

OraSure Technologies Reports 4Q21 Revenue of $63.6 Million; InteliSwab® Production Scales Up Total 2021 revenue of $233.7 million, up 36% year-over year InteliSwab® receives emergency use authorization expansion and demonstrates accurate detection of

EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Technologies Reports 4Q21 Revenue of $63.6 Million; InteliSwab? Production Scales Up Total 2021 revenue of $233.7 million, up 36% year-over year InteliSwab? receives

February 23, 2022 EX-99.2

4Q21 and FY21 Financial Results FINANCIAL METRIC 4Q21/FY21 RESULTS 4Q20/FY20 RESULTS YEAR-OVER-YEAR GROWTH RATE Quarterly Revenue $63.6 million $62.9 million 1% Annual Revenue $233.7 million $171.7 million 36% Annual Revenue Diagnostics $90.0 million

OraSure 4Q21 Earnings February 23, 2022 EXHIBIT 99.2 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to products, product development activities, regulatory submissions and authorizations and other matters. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could

February 10, 2022 EX-4.1

Specimen Certificate representing shares of the Company’s $0.000001 par value Common Stock.

Exhibit 4.1 ORASURE TECHNOLOGIES, INC. THE CORPORATION WILL FURNISH WITHOUT CHARGE TO EACH SHAREHOLDER WHO SO REQUESTS, A SUMMARY OF THE POWERS, DESIGNATIONS, PREFERENCES AND RELATIVE, PARTICIPATING, OPTIONAL OR OTHER SPECIAL RIGHTS OF EACH CLASS OF STOCK OF THE CORPORATION AND THE QUALIFICATIONS, LIMITATIONS OR RESTRICTIONS OF SUCH PREFERENCES AND RIGHTS, AND THE VARIATIONS IN RIGHTS, PREFERENCES

February 10, 2022 EX-4.4.1

Form of Indenture to be entered into between the Company and a Trustee acceptable to the Company.

Exhibit 4.4.1 FORM OF INDENTURE ORASURE TECHNOLOGIES, INC., as Issuer, and [ ], as Trustee Indenture Dated as of [ ] Providing for the Issuance Of Debt Securities ORASURE TECHNOLOGIES, INC. Reconciliation and tie between Trust Indenture Act of 1939 and indenture, dated as of [ ] Trust Indenture Act Section Indenture Section ?310 (a)(1) 6.07 (a)(2) 6.07 (b) 6.09 ?311 (a) 7.06 (b) 7.06 ?312 (a) 7.01

February 10, 2022 S-3

As filed with the Securities and Exchange Commission on February 10, 2022

Table of Contents As filed with the Securities and Exchange Commission on February 10, 2022 Registration No.

February 10, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables FORM S-3 (Form Type) OraSure Technologies, Inc.

February 10, 2022 SC 13G/A

OSUR / OraSure Technologies, Inc. / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv01591-orasuretechnologiesi.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 5)* Name of issuer: OraSure Technologies Inc. Title of Class of Securities: Common Stock CUSIP Number: 68554V108 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box

January 26, 2022 SC 13G/A

OSUR / OraSure Technologies, Inc. / MANAGED ACCOUNT ADVISORS LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 01)* ORASURE TECHNOLOGIES INC (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

January 10, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): January 5, 2022 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

January 6, 2022 EX-10.1

Transition Agreement dated as of January 2, 2022, between OraSure Technologies, Inc. and Stephen S. Tang, Ph.D. is incorporated by reference to Exhibit 10.1 to the Company's Current Report on Form 8-k filed January 6, 2022*

TRANSITION AGREEMENT This Transition Agreement (?Agreement?) is made on January 2, 2022 by and between Stephen S.

January 6, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 31, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

November 10, 2021 EX-14.1

Amended and Restated Code of Business Conduct and Ethics of OraSure Technologies, Inc. is incorporated by reference to Exhibit 14.1 to the Company’s Current Report on Form 8-K filed November 10, 2021.

EXHIBIT 14.1 ORASURE TECHNOLOGIES, INC. CODE OF BUSINESS CONDUCT AND ETHICS (As amended through November 8, 2021) Introduction The reputation and integrity of OraSure Technologies, Inc. (together with its subsidiaries, the ?Company? or ?we?) are valuable assets that are vital to the Company?s success. Each director, officer and employee of the Company is therefore responsible for conducting the Co

November 10, 2021 8-K

Amendment to Registrant's Code of Ethics, or Waiver of a Provision of the Code of Ethics, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 8, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 9, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 8, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 9, 2021 EX-99.1

OraSure Technologies Announces the Retirement of Jack E. Jerrett and Appointment of Agnieszka M. Gallagher as General Counsel, Chief Compliance Officer and Secretary

EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO & SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Technologies Announces the Retirement of Jack E. Jerrett and Appointment of Agnieszka M. Gallagher as General Counsel, Chief Compliance Officer and Secretary BETHLE

November 9, 2021 EX-10.1

Retirement Agreement, dated as November 9, 2021, between OraSure Technologies, Inc. and Jack E. Jerrett is incorporated by reference to Exhibit 10.1 to the Company’s Current Report on For 8-K filed November 9, 2021.*

EXHIBIT 10.1 RETIREMENT AGREEMENT This Retirement Agreement (?Agreement?) is made as of November 9, 2021, by and between Jack E. Jerrett (?Executive?) and OraSure Technologies, Inc. (collectively, with its predecessors, successors, affiliates and subsidiaries, the ?Company?) (jointly referred to as the ?Parties? and singularly as a ?Party?): RECITALS WHEREAS, Executive has been employed by the Com

November 8, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 7, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 8, 2021 EX-1

JOINT FILING AGREEMENT

EX-1 2 OSUR13Dex.htm JOINT FILING AGREEMENT EXHIBIT 1 JOINT FILING AGREEMENT This Joint Filing Agreement dated November 08, 2021 is by and between Camber Capital Management LP, a Delaware limited partnership, and Stephen DuBois, an individual (the foregoing are collectively referred to herein as the "Filers"). Each of the Filers may be required to file with the United States Securities and Exchang

November 8, 2021 SC 13D

OSUR / OraSure Technologies, Inc. / Camber Capital Management LP - PRIMARY DOCUMENT Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 ORASURE TECHNOLOGIES, INC (Name of Issuer) Common stock, $0.000001 par value (Title of Class of Securities) 68554V108 (CUSIP Number) Camber Capital Management LP, 101 Huntington Avenue, Suite 2101, Boston, MA 02199 617-717-6600 (Name, Address and Telephone Number of Person

November 8, 2021 EX-99.1

OraSure Technologies Appoints Two New Members to the Board of Directors New Appointments Bring to the Company Significant Executive Leadership, Global Product Development, Public Health, and the Retail Pharmacy Market Experience

EX-99.1 2 osur-ex991.htm EX-99.1 EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO & SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Technologies Appoints Two New Members to the Board of Directors New Appointments Bring to the Company Significant Executive Leaders

November 4, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORA

November 4, 2021 EX-10.2

$109 Million Capital Funding Agreement with the U.S. Department of Defense, in coordination with the Department of Health and Human Services is incorporated by reference to Exhibit 10.2 to the Company's Quarterly Report on From 10-Q for the period ended September 30, 2021, filed November 4, 2021.

EX-10.2 3 osur-ex102.htm EX-10.2 EXHIBIT 10.2 Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain identified information marked with [***] has been excluded from this exhibit because it is both (i) not material and (ii) is of the type that the registrant treats as private or confidential. SOLICITATION/CONTRACT/ORDER FOR COMMERCIAL ITEMS OFFEROR TO COMPLETE BLOCKS 12, 17, 23, 24, & 30 1. REQ

November 4, 2021 EX-10.1

Change of Control Severance Letter of Michele Miller, Vice President, Finance and Controller.

Exhibit 10.1 August 25, 2021 Ms. Michele M. Miller Vice President, Finance and Controller Re: Severance Benefit Dear Michele: As a valued employee of OraSure Technologies, Inc. (the “Company”), the Company would like to provide you with certain compensation in the event that your employment is terminated by the Company without Cause (as defined below) or by you for Good Reason (as defined below),

November 3, 2021 EX-99.3

Forward-Looking Statements Disclaimer This document contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results.

EX-99.3 4 osur-ex993.htm EX-99.3 OraSure 3Q21 Earnings November 3, 2021 EXHIBIT 99.3 Forward-Looking Statements Disclaimer This document contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or

November 3, 2021 EX-99.1

OraSure Technologies Reports 3Q21 Revenue of $53.9 Million, Signs Three Major U.S. Government Contracts Positioning the Company for Significant InteliSwab™ Growth in FY22

EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Technologies Reports 3Q21 Revenue of $53.9 Million, Signs Three Major U.S. Government Contracts Positioning the Company for Significant InteliSwab? Growth in FY22 ? T

November 3, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 3, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 3, 2021 EX-99.2

OraSure Technologies, Inc. Third Quarter 2021 Analyst-Investor Conference Call November 3, 2021 Prepared Remarks of Dr. Stephen S. Tang and Scott Gleason Please see “Important Information” at the conclusion of the following prepared remarks

EX-99.2 3 osur-ex992.htm EX-99.2 EXHIBIT 99.2 OraSure Technologies, Inc. Third Quarter 2021 Analyst-Investor Conference Call November 3, 2021 Prepared Remarks of Dr. Stephen S. Tang and Scott Gleason Please see “Important Information” at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies third quarter 2021 financial res

October 4, 2021 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 30, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissi

October 4, 2021 EX-99.1

OraSure Awarded $109 Million Contract from U.S. Department of Defense to Ramp Manufacturing of InteliSwab™ COVID-19 Rapid Test Agreement Ensures OraSure Will Have Sufficient Capacity to Meet Market Need for Rapid Antigen Tests and Ensure Future Prepa

EX-99.1 2 osur-ex991.htm EX-99.1 Exhibit 99.1 Investor Contact: Scott Gleason SVP Investor Relations & Corporate Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Awarded $109 Million Contract from U.S. Department of Defense to Ramp Manufacturing of InteliSwab™ COVID-19 Rapid Test Agreement Ensures OraS

September 23, 2021 EX-99.1

OraSure to Receive up to $13.6 Million from Biomedical Advanced Research Development Authority to Support InteliSwab™ COVID-19 Rapid Test 510(k) Clearance and CLIA Waiver

EX-99.1 2 osur-20210917ex991.htm EX-99.1 EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO, SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure to Receive up to $13.6 Million from Biomedical Advanced Research Development Authority to Support InteliSwab™ COVID-19 Rapid

September 23, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 17, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissi

September 20, 2021 EX-99.1

OraSure Receives $205 Million Procurement Contract for InteliSwab™ from the Defense Logistics Agency to Supply Over-the-Counter (OTC) Kits as Part of National Pandemic Response

EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO, SVP Investor Relations & Corp. Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Receives $205 Million Procurement Contract for InteliSwab? from the Defense Logistics Agency to Supply Over-the-Counter (OTC) Kits as Part of National Pandemic Respo

September 20, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 14, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissi

September 8, 2021 EX-99.1

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

Investor Presentation August 2021 EXHIBIT 99.1 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or results to be materially different

September 8, 2021 8-K

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): September 8, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

September 2, 2021 EX-99.1

OraSure Technologies Announces Resignation of CFO Roberto Cuca and Succession Plan Scott Gleason, SVP, Investor Relations and Corporate Communications, Will Serve as Interim CFO

EX-99.1 2 osur-20210827ex991.htm EX-99.1 EXHIBIT 99.1 Investor Contact: Scott Gleason Interim CFO & SVP Investor Relations & Corporate Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-523-1815 [email protected] OraSure Technologies Announces Resignation of CFO Roberto Cuca and Succession Plan Scott Gleason, SVP, Investor Relations and C

September 2, 2021 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported):August 27, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 13, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 9, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 5, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

August 3, 2021 EX-99.1

OraSure Technologies Reports 2Q21 Revenue of $57.6 Million Driven by Strong Rebound in Core Business

EXHIBIT 99.1 Investor Contact: Scott Gleason SVP Investor Relations & Corporate Communications 484-425-0588 [email protected] Media Contact: Amy Koch Sr. Mgr. Corporate Communications 484-353-1815 [email protected] OraSure Technologies Reports 2Q21 Revenue of $57.6 Million Driven by Strong Rebound in Core Business ? Excluding COVID-19 product revenues, revenues for the second quarter grew 122%

August 3, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 3, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 3, 2021 EX-99.2

OraSure Technologies, Inc. Second Quarter 2021 Analyst-Investor Conference Call August 3, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks

EX-99.2 3 osur-20210803ex992.htm EX-99.2 EXHIBIT 99.2 OraSure Technologies, Inc. Second Quarter 2021 Analyst-Investor Conference Call August 3, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies second quarter 2021 financ

August 3, 2021 EX-99.3

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

EX-99.3 4 osur-20210803ex993.htm EX-99.3 OraSure 2Q21 Earnings August 3, 2021 EXHIBIT 99.3 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual perfo

July 29, 2021 EX-1

JOINT FILING AGREEMENT

EX-1 2 osur13g2021ex1.htm JOINT FILING AGREEMENT EXHIBIT 1 JOINT FILING AGREEMENT This Joint Filing Agreement dated July 29, 2021 is by and between Camber Capital Management LP, a Delaware limited partnership, and Stephen DuBois, an individual (the foregoing are collectively referred to herein as the "Filers"). Each of the Filers may be required to file with the United States Securities and Exchan

July 29, 2021 SC 13G

OSUR / OraSure Technologies, Inc. / Camber Capital Management LP - PRIMARY DOCUMENT Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 ORASURE TECHNOLOGIES, INC. (Name of Issuer) Common Stock, $0.000001 par value per share (Title of Class of Securities) 68554V108 (CUSIP Number) July 19, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to

May 26, 2021 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 21, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 18, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 18, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 6, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021. OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

May 5, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 5, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission File

May 5, 2021 EX-99.1

OraSure Technologies, Inc. Announces First Quarter 2021 Financial Results and Provides COVID-19 Update First Quarter 2021 Net Revenues of $59 Million Increased 85% Over 2020, Driven by $27 Million in Sales of Sample Collection Devices for COVID-19 Mo

EX-99.1 2 osur-ex991117.htm EX-99.1 Exhibit 99.1 Investor Contact: Sam Martin Argot Partners 212-600-1902 [email protected] Media Contact Jeanne Mell OraSure Technologies 484-353-1575 [email protected] OraSure Technologies, Inc. Announces First Quarter 2021 Financial Results and Provides COVID-19 Update First Quarter 2021 Net Revenues of $59 Million Increased 85% Over 2020, Driven by $27 M

May 5, 2021 EX-99.3

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

EX-99.3 4 osur-ex993205.htm EX-99.3 OraSure Technologies Investor presentation MAy 2021 Exhibit 99.3 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause ac

May 5, 2021 EX-99.2

OraSure Technologies, Inc. First Quarter 2021 Analyst-Investor Conference Call May 5, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks

Exhibit 99.2 OraSure Technologies, Inc. First Quarter 2021 Analyst-Investor Conference Call May 5, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see ?Important Information? at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies first quarter 2021 financial results conference call and simultaneous w

April 8, 2021 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 8, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

March 1, 2021 EX-99.1

OraSure Technologies, Inc. Announces 2020 Full-Year and Fourth Quarter Financial Results and Provides COVID-19 Update Full-Year 2020 Net Revenues of $172 Million Increased 11% Year-Over-Year, Driven by $50 Million in Sales of Oral Fluid Collection De

EXHIBIT 99.1 Investor contact: Sam Martin Argot Partners 212-600-1902 [email protected] Media contact: Jeanne Mell OraSure Technologies 484-353-1575 [email protected] OraSure Technologies, Inc. Announces 2020 Full-Year and Fourth Quarter Financial Results and Provides COVID-19 Update Full-Year 2020 Net Revenues of $172 Million Increased 11% Year-Over-Year, Driven by $50 Million in Sales of

March 1, 2021 EX-99.3

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

OraSure Technologies Investor presentation March 2021 Exhibit 99.3 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or results to be

March 1, 2021 EX-99.2

OraSure Technologies, Inc. 2020 Fourth Quarter and Full Year Analyst-Investor Conference Call March 1, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remark

EX-99.2 3 osur-ex99267.htm EX-99.2 EXHIBIT 99.2 OraSure Technologies, Inc. 2020 Fourth Quarter and Full Year Analyst-Investor Conference Call March 1, 2021 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies 2020 fourth quarter

March 1, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): March 1, 2021 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 1, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? Annual report pursuant to Section 13 or 15(d) of the Securities Exchange ACT OF 1934 For the fiscal year ended December 31, 2020 or ? Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 For the transition period from to Commission File No. 001-16537 ORASURE TECHNOLOGI

March 1, 2021 EX-24

Powers of Attorney.

EX-24 3 osur-ex2410.htm EX-24 Exhibit 24 POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned constitutes and appoints Michele Miller and Jack E. Jerrett, and each of them, his true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution for the undersigned and in the undersigned’s name, place, and stead, in any and all capacities, to sign the

February 16, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendme

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. )* OraSure Technologies, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) 12/31/2020 (Date of Event W

February 12, 2021 SC 13G/A

SCHEDULE 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* OraSure Technologies Inc (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which th

February 10, 2021 SC 13G/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 4)*

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 4)* Name of issuer: OraSure Technologies Inc. Title of Class of Securities: Common Stock CUSIP Number: 68554V108 Date of Event Which Requires Filing of this Statement: December 31, 2020 Check the appropriate box to designate the rule pursuant to which this Schedule is fi

February 4, 2021 SC 13G/A

SCHEDULE 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* ORASURE TECHNOLOGIES INC (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which th

February 3, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. n/a )* OraSure Technologies Inc (Name of Issuer) Common Stock (Title of Class of Securities) (CUSIP Number)

Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. n/a )* OraSure Technologies Inc (Name of Issuer) Common Stock (Title of Class of Securities) 68554V108 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursu

December 21, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): December 21, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commissio

December 21, 2020 EX-99.1

OraSure Technologies Provides Update on Its Emergency Use Authorization Application for Its Lab-based Oral Fluid SARS-CoV-2 Antibody Test

Exhibit 99.1 Investor Contact:Media Contact: Sam MartinJeanne Mell Argot PartnersVP Corporate Communications 212-600-1902484-353-1575 [email protected]@orasure.com OraSure Technologies Provides Update on Its Emergency Use Authorization Application for Its Lab-based Oral Fluid SARS-CoV-2 Antibody Test BETHLEHEM, Pa., December 21, 2020 - OraSure Technologies, Inc. (NASDAQ: OSUR), a lead

December 21, 2020 EX-99.2

Questions and Answers Regarding OraSure Technologies, Inc. EUA Application for Lab-based Oral Fluid SARS-CoV-2 Update – December 2020

EX-99.2 3 osur-ex99224.htm EX-99.2 Exhibit 99.2 Questions and Answers Regarding OraSure Technologies, Inc. EUA Application for Lab-based Oral Fluid SARS-CoV-2 Update – December 2020 1. What additional information has FDA requested? • The FDA requested that OraSure perform additional analytical studies related to collection and stability in support of the use of oral fluid as a sample matrix. • The

December 21, 2020 EX-99.3

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

OraSure Technologies Investor presentation december 2020 Exhibit 99.3 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or results to

November 5, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 5, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

November 5, 2020 EX-99.1

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

OraSure Technologies Investor presentation NOVEMBER 2020 Exhibit 99.1 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or results to

November 5, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2020. OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORA

November 4, 2020 EX-99.1

OraSure Technologies, Inc. Announces Third Quarter 2020 Financial Results and Provides Update on COVID-19 Developments Net Third Quarter Revenues of $48.0 Million Increased 33% Year-Over-Year, Driven by $18.4 Million in Sales of Oral Fluid Collection

Exhibit 99.1 Investor contact: Media contact: Sam Martin Jeanne Mell Argot Partners VP Corporate Communications 212-600-1902 484-353-1575 [email protected] [email protected] OraSure Technologies, Inc. Announces Third Quarter 2020 Financial Results and Provides Update on COVID-19 Developments Net Third Quarter Revenues of $48.0 Million Increased 33% Year-Over-Year, Driven by $18.4 Million i

November 4, 2020 EX-99.2

OraSure Technologies, Inc. 2020 Third Quarter Analyst-Investor Conference Call November 4, 2020 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks

Exhibit 99.2 OraSure Technologies, Inc. 2020 Third Quarter Analyst-Investor Conference Call November 4, 2020 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies 2020 third quarter financial results conference call and simultane

November 4, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): November 4, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

September 1, 2020 EX-99.1

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

OraSure Technologies Investor presentation september 2020 Exhibit 99.1 Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or results. Known and unknown factors that could cause actual performance or results to

September 1, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 31, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

August 26, 2020 EX-24

Power of Attorney.

Exhibit 24 POWER OF ATTORNEY Each person whose signature appears below constitutes and appoints Michele Miller and Jack E.

August 26, 2020 S-8

- S-8

Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ORASURE TECHNOLOGIES, INC. (Exact Name of Registrant as Specified in Its Charter) Delaware 36-4370966 (State or Other Jurisdiction of Incorporation or Organization) (IRS Employer Identification No.) 220 East First Street Bethlehem, PA 18015

August 25, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 25, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission

August 25, 2020 EX-99.1

Forward-Looking Statements Disclaimer This presentation contains certain forward-looking statements, including with respect to expected revenues and earnings/loss per share. Forward-looking statements are not guarantees of future performance or resul

OraSure Technologies Summary of Recent CoVID-19 Communications August 25, 2020 Exhibit 99.

August 10, 2020 SC 13G

OSUR / OraSure Technologies, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

August 6, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2020. OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

August 6, 2020 EX-10.2

Employment Agreement, dated as of May 11, 2020, between OraSure Technologies, Inc. and Lisa Nibauer is incorporated by reference to Exhibit 10.2 to the Company’s Quarterly Report on form 10-Q for the quarter ended June 30, 2020.*

EX-10.2 2 osur-ex102142.htm EX-10.2 Exhibit 10.2 EMPLOYMENT AGREEMENT This Employment Agreement (this “Agreement”) is entered into as of May 11, 2020 (the “Effective Date”), between Lisa A. Nibauer (“Employee”) and OraSure Technologies, Inc. (“OraSure” or the “Company”). WHEREAS, the parties wish to set forth the terms of their relationship and to enter into this Agreement and a confidentiality ag

August 5, 2020 EX-99.2

OraSure Technologies, Inc. 2020 Second Quarter Analyst-Investor Conference Call August 5, 2020 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks

EXHIBIT 99.2 OraSure Technologies, Inc. 2020 Second Quarter Analyst-Investor Conference Call August 5, 2020 Prepared Remarks of Dr. Stephen S. Tang and Roberto Cuca Please see “Important Information” at the conclusion of the following prepared remarks Operator Remarks Good afternoon everyone and welcome to the OraSure Technologies 2020 second quarter financial results conference call and simultane

August 5, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): August 5, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission F

August 5, 2020 EX-99.1

OraSure Technologies, Inc. Announces 2020 Second Quarter Financial Results and Update on COVID-19 Testing Programs

Exhibit 99.1 Investor contact: Sam Martin Argot Partners 212-600-1902 [email protected] Media contact: Jeanne Mell VP Corporate Communications 484-353-1575 [email protected] OraSure Technologies, Inc. Announces 2020 Second Quarter Financial Results and Update on COVID-19 Testing Programs BETHLEHEM, PA, August 5, 2020 (GLOBE NEWSWIRE) - OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in

June 4, 2020 EX-99.2

OraSure Technologies, Inc. Announces Exercise of Option to Purchase Additional Shares of Common Stock

EX-99.2 Exhibit 99.2 Investor Contact: Media Contact: Sam Martin Jeanne Mell Argot Partners 212-600-1902 VP Corporate Communications 484-353-1575 [email protected] [email protected] OraSure Technologies, Inc. Announces Exercise of Option to Purchase Additional Shares of Common Stock BETHLEHEM, Pa., June 3, 2020 (Globe Newswire) – OraSure Technologies, Inc. (Nasdaq: OSUR) (“OraSure” or the

June 4, 2020 EX-99.1

OraSure Technologies, Inc. Prices Underwritten Offering of Common Stock

EX-99.1 Exhibit 99.1 Investor Contact: Media Contact: Sam Martin Jeanne Mell Argot Partners VP Corporate Communications 212-600-1902 484-353-1575 [email protected] [email protected] OraSure Technologies, Inc. Prices Underwritten Offering of Common Stock BETHLEHEM, Pa., June 2, 2020 (Globe Newswire) – OraSure Technologies, Inc. (Nasdaq: OSUR) (“OraSure” or the “Company”) today announced the

June 4, 2020 EX-1.1

Underwriting Agreement among the Company and J.P. Morgan Securities LLC, Citigroup Global Markets Inc. and Evercore Group L.L.C., as representatives of the underwriters named therein, dated as of June 2, 2020.

EX-1.1 Exhibit 1.1 Execution Version ORASURE TECHNOLOGIES, INC. 8,000,000 Shares of Common Stock Underwriting Agreement June 2, 2020 J.P. Morgan Securities LLC Citigroup Global Markets Inc. and Evercore Group L.L.C. As Representatives of the several Underwriters listed in Schedule 1 hereto c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 c/o Citigroup Global Markets Inc.

June 4, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): June 2, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

June 3, 2020 424B5

Corporate Secretary OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 (610) 882-1820

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration Statement No.

June 2, 2020 EX-99.1

OraSure Technologies, Inc. Announces Proposed Public Offering of Common Stock

EX-99.1 Exhibit 99.1 Investor Contact: Media Contact: Sam Martin Jeanne Mell Argot Partners 212-600-1920 VP Corporate Communications 484-353-1575 [email protected] [email protected] OraSure Technologies, Inc. Announces Proposed Public Offering of Common Stock BETHLEHEM, Pa., June 1, 2020 (Globe Newswire) – OraSure Technologies, Inc. (Nasdaq: OSUR) (“OraSure” or the “Company”) today announc

June 2, 2020 424B5

Corporate Secretary OraSure Technologies, Inc. 220 East First Street Bethlehem, Pennsylvania 18015 (610) 882-1820

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration Statement No.

June 2, 2020 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): June 1, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 29, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 29, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 29, 2020 EX-99.1

ORASURE TECHNOLOGIES APPOINTS LELIO MARMORA TO BOARD OF DIRECTORS

Exhibit 99.1 Investor Contact: Sam Martin Argot Partners 212-600-1902 [email protected] Media Contact: Jeanne Mell VP Corporate Communications 484-353-1575 [email protected] ORASURE TECHNOLOGIES APPOINTS LELIO MARMORA TO BOARD OF DIRECTORS BETHLEHEM, PA, May 29, 2020 - OraSure Technologies, Inc. (NASDAQ: OSUR), a leader in point of care diagnostic tests, specimen collection devices, and mi

May 29, 2020 EX-99.2

OraSure Technologies, Inc. Announces Purchase of UrSure, Inc. Acquisition strengthens OraSure’s leadership position in HIV field

Exhibit 99.2 Company contacts: Investors: Media: Samuel Martin Jeanne Mell Argot Partners VP Corporate Communications 212-600-1902 484-353-1575 [email protected] [email protected] OraSure Technologies, Inc. Announces Purchase of UrSure, Inc. Acquisition strengthens OraSure’s leadership position in HIV field Bethlehem, PA – May 29, 2020 – OraSure Technologies, Inc. (NASDAQ: OSUR), a leader

May 19, 2020 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of Report (Date of earliest event reported): May 19, 2020 OraSure Technologies, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-16537 36-4370966 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 11, 2020 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2020. OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to . Commission File Number 001-16537 ORASURE

May 11, 2020 EX-10.3

Employment Agreement dated as of May 11, 2020 between OraSure Technologies, Inc. and Lisa A. Nibauer

Exhibit 10.3 EMPLOYMENT AGREEMENT This Employment Agreement (this “Agreement”) is entered into as of May 11, 2020 (the “Effective Date”), between Lisa A. Nibauer (“Employee”) and OraSure Technologies, Inc. (“OraSure” or the “Company”). WHEREAS, the parties wish to set forth the terms of their relationship and to enter into this Agreement and a confidentiality agreement of even date herewith (the “

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