NBSE / NeuBase Therapeutics, Inc. - SEC Filings, Annual Report, Proxy Statement

NeuBase Therapeutics, Inc.
US ˙ NasdaqCM ˙ US64132K2015
THIS SYMBOL IS NO LONGER ACTIVE

Basic Stats
LEI 529900RHAZB85RGSJZ73
CIK 1173281
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to NeuBase Therapeutics, Inc.
SEC Filings (Chronological Order)
This page provides a complete, chronological list of SEC Filings, excluding ownership filings which we provide elsewhere.
January 13, 2025 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File No. 001-35963 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in

January 7, 2025 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 2, 2025 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

June 27, 2024 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File No. 001-35963 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in

June 27, 2024 S-8 POS

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 POS AM

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 S-8 POS

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 EX-4.1

State of Delaware Certificate of Dissolution (Section 275)

Exhibit 4.1 State of Delaware Certificate of Dissolution (Section 275) NeuBase Therapeutics, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware (the “Corporation”), hereby certifies as follows: 1. The dissolution of the Corporation (the “Dissolution”) has been duly authorized by the board of directors of the Corporation and the holders of a majori

June 27, 2024 8-K

Material Modification to Rights of Security Holders, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 26, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

June 27, 2024 POS AM

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 S-8 POS

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 S-8 POS

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 27, 2024 S-8 POS

As filed with the Securities and Exchange Commission on June 27, 2024

As filed with the Securities and Exchange Commission on June 27, 2024 Registration No.

June 3, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. __)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a party other than the Registrant ¨ Check the appropriate box: ¨ ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(

May 31, 2024 EX-3.1

CERTIFICATE OF AMENDMENT TO AMENDED AND RESTATED BYLAWS OF NEUBASE THERAPEUTICS, INC.

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO AMENDED AND RESTATED BYLAWS OF NEUBASE THERAPEUTICS, INC. The undersigned hereby certifies that he is the duly elected, qualified and acting Interim Chief Executive Officer of NeuBase Therapeutics, Inc., a Delaware corporation (the “Corporation”), and that the Amended and Restated Bylaws of the Corporation (as amended from time to time, the “Bylaws”) were am

May 31, 2024 EX-3.2

CERTIFICATE OF DESIGNATION OF SERIES A PREFERRED STOCK OF NEUBASE THERAPEUTICS, INC.

Exhibit 3.2 CERTIFICATE OF DESIGNATION OF SERIES A PREFERRED STOCK OF NEUBASE THERAPEUTICS, INC. NeuBase Therapeutics, Inc., a Delaware corporation (the “Corporation”), does hereby certify that, pursuant to the authority conferred upon the Board of Directors of the Corporation (the “Board of Directors”) by the Amended and Restated Certificate of Incorporation of the Corporation (as amended and/or

May 31, 2024 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Material Modification to Rights of Security Holders, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 28, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 31, 2024 EX-10.1

SUBSCRIPTION AND INVESTMENT REPRESENTATION AGREEMENT

Exhibit 10.1 SUBSCRIPTION AND INVESTMENT REPRESENTATION AGREEMENT THIS SUBSCRIPTION AND INVESTMENT REPRESENTATION AGREEMENT, dated as of May 29, 2024 (this “Agreement”), is by and between NeuBase Therapeutics, Inc., a Delaware corporation (the “Company”), and the undersigned subscriber (the “Subscriber”). In consideration of the mutual promises contained herein, and other good, valuable and adequa

May 22, 2024 8-K

Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 22, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 14, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive

May 13, 2024 8-K

Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 13, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 6, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ¨ Definitive

May 3, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 2, 2024 NeuBase Therapeutics,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 2, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

April 9, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant ☒ Filed by a party other than the Registrant ☐ Check the appropriate box: ☐ ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as per

April 5, 2024 EX-99.1

NeuBase Therapeutics Announces Receipt of Notice from Nasdaq

Exhibit 99.1 NeuBase Therapeutics Announces Receipt of Notice from Nasdaq PITTSBURGH, April 5, 2024 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”) today reported that it received a notice (the “Notice) on April 4, 2024 from the Listing Qualifications Department of The Nasdaq Stock Market LLC (“Nasdaq”) notifying the Company that it was not in compliance with Nasdaq’s cont

April 5, 2024 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 4,2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

March 25, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.    ) Filed by the Registrant ☒ Filed by a party other than the Registrant ☐ Check the appropriate box: ☐ ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as per

March 7, 2024 EX-2.1

PLAN OF LIQUIDATION AND DISSOLUTION OF NEUBASE THERAPEUTICS, INC.

Exhibit 2.1 PLAN OF LIQUIDATION AND DISSOLUTION OF NEUBASE THERAPEUTICS, INC. This Plan of Liquidation and Dissolution (the “Plan”) is intended to accomplish the complete liquidation and dissolution of NEUBASE THERAPEUTICS, INC., a Delaware corporation (such corporation or a successor entity, the “Company”), in accordance with Section 281(b) of the General Corporation Law of the State of Delaware

March 7, 2024 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 5, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

February 23, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 22, 2024 NeuBase Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 22, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

February 14, 2024 SC 13G/A

US64132K2015 / NeuBase Therapeutics, Inc. / GREENLIGHT CAPITAL INC - AMENDMENT NO. 3 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* NeuBase Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 64132K201 (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate

January 26, 2024 EX-10.1

redemption and termination Agreement

Exhibit 10.1 redemption and termination Agreement This Redemption and Termination Agreement (this “Agreement”) is dated as of January 26, 2024, by and between NeuBase Therapeutics, Inc. or any Successor Entity thereto (together, the “Company”) and Armistice Capital Master Fund Ltd. (the “Warrant Holder”). Capitalized terms used and not otherwise defined herein shall have the meanings set forth in

January 26, 2024 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 26, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

January 17, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 12, 2024 NeuBase Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 12, 2024 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

December 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 27, 2023 NeuBase Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 27, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 28, 2023 EX-10.2

BILL OF SALE

Exhibit 10.2 BILL OF SALE THIS BILL OF SALE (this “Bill of Sale”) is dated as of this 27th day of December, 2023, by NEUBASE THERAPEUTICS, INC., a Delaware corporation (the “Transferor”) for the benefit of UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, a Pennsylvania non-profit corporation (the “Transferee”). WITNESSETH: WHEREAS, Transferor and 350 Technology Drive Partne

December 28, 2023 EX-10.1

LEASE TERMINATION AND MUTUAL RELEASE AGREEMENT

Exhibit 10.1 LEASE TERMINATION AND MUTUAL RELEASE AGREEMENT THIS LEASE TERMINATION AND MUTUAL RELEASE AGREEMENT (this “Agreement”) is made as of this 27 day of December, 2023 (the “Effective Date”), by and between 350 TECHNOLOGY DRIVE PARTNERS, LLC, a Pennsylvania limited liability company (“Landlord”), and NEUBASE THERAPEUTICS, INC., a Delaware corporation (“Tenant”). RECITALS WHEREAS, Landlord a

December 28, 2023 424B3

293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-254980 SUPPLEMENT NO. 2 TO PROSPECTUS SUPPLEMENT DATED DECEMBER 29, 2022 (to Prospectus dated April 14, 2021) 293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock This Supplement No. 2 to Prospectus Supplement (this “Supplement No. 2”) amends and supplements the information in the prospectus, dated April 14, 2021 (the “Pro

December 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2023 NeuBase Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

November 9, 2023 10-Q

3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents 3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended September 30, 2023 Or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to. Commission File Number

November 6, 2023 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 3, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

October 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 17, 2023 NeuBase Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 17, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

October 18, 2023 EX-4.1

SERIES A-1 COMMON STOCK PURCHASE WARRANT NEUBASE THERAPEUTICS, INC.

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

October 18, 2023 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 17, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

October 18, 2023 EX-10.1

exchange Agreement

Exhibit 10.1 exchange Agreement This Exchange Agreement (this “Agreement”) is dated as of October 17, 2023, by and between NeuBase Therapeutics, Inc. or any Successor Entity thereto (together, the “Company”) and Armistice Capital Master Fund Ltd. (the “Warrant Holder”). Capitalized terms used and not otherwise defined herein shall have the meanings set forth in the Securities Purchase Agreements (

September 29, 2023 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 28, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Comm

September 20, 2023 SC 13D/A

US64132K2015 / NeuBase Therapeutics, Inc. / Symetryx Corp - AMENDMENT NO. 2 TO SCHEDULE 13D Activist Investment

SC 13D/A 1 ea185515-13da2symetryxneuba.htm AMENDMENT NO. 2 TO SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION, Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 2) NeuBase Therapeutics, Inc. (Name of Issuer) Common stock, par value $0.0001 (Title of Class of Securities) 64132K201 (CUSIP Number) Barry Shiff, 2828 Bathurst Street, Suite 400,

September 18, 2023 EX-3.1

CERTIFICATE OF AMENDMENT TO AMENDED AND RESTATED BYLAWS OF NEUBASE THERAPEUTICS, INC.

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO AMENDED AND RESTATED BYLAWS OF NEUBASE THERAPEUTICS, INC. The undersigned hereby certifies that he is the duly elected, qualified and acting Chief Executive Officer of NeuBase Therapeutics, Inc., a Delaware corporation (the “Corporation”), and that the Amended and Restated Bylaws of the Corporation (the “Bylaws”) were amended by unanimous written consent of

September 18, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 15, 2023 NeuBase Therap

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 15, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Comm

September 18, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. 1) Filed by the Registrant x Filed by a party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e

September 14, 2023 SC 13D/A

US64132K2015 / NeuBase Therapeutics, Inc. / Symetryx Corp - AMENDMENT NO. 1 TO SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION, Washington, D.C. 20549 SCHEDULE 13D/A Under the Securities Exchange Act of 1934 (Amendment No. 1) NeuBase Therapeutics, Inc. (Name of Issuer) Common stock, par value $0.0001 (Title of Class of Securities) 64132K201 (CUSIP Number) Barry Shiff, 2828 Bathurst Street, Suite 400, Toronto, Canada M6B-3A7, 416-453-7832 (Name, Address and Telephone Number

August 31, 2023 SC 13D

US64132K2015 / NeuBase Therapeutics, Inc. / Symetryx Corp - SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION, Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No.)* Neubase Therapeutics, Inc. (Name of Issuer) Common stock, par value $0.0001 (Title of Class of Securities) 64132K201 (CUSIP Number) Barry Shiff, 2828 Bathurst Street, Suite 400, Toronto, Canada M6B-3A7, 416-453-7832 (Name, Address and Telephone Number of

August 31, 2023 EX-99.1

1

EX-99.1 2 ea184525ex99-1neubase.htm PURCHASES BY REPORTING PERSONS OF SHARES OF ISSUER COMMON STOCK DURING THE PAST 60 DAYS Exhibit 99.1 Purchases by Reporting Persons of Shares of Issuer Common Stock During the Past Sixty Days Trade Date Quantity Trade Price Transaction Purchaser August 21, 2023 7,700 0.673 On market Symetryx Corporation August 21, 2023 5,100 0.663 On market Symetryx Corporation

August 31, 2023 EX-99.2

Barry Shiff Power of Attorney for Legal Counsel to Make SEC Filings LIMITED POWER OF ATTORNEY FOR FILINGS UNDER THE SECURITIES ACT OF 1933, AS AMENDED AND THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED

EX-99.2 3 ea184525ex99-2neubase.htm POWER OF ATTORNEY OF SYMETRYX AND BARRY SHIFF AUTHORIZING LEGAL COUNSEL TO CAUSE THIS SCHEDULE 13D TO BE FILED WITH THE SECURITIES AND EXCHANGE COMMISSION Exhibit 99.2 Barry Shiff Power of Attorney for Legal Counsel to Make SEC Filings LIMITED POWER OF ATTORNEY FOR FILINGS UNDER THE SECURITIES ACT OF 1933, AS AMENDED AND THE SECURITIES EXCHANGE ACT OF 1934, AS A

August 31, 2023 EX-99.3

Aleta Shiff Power of Attorney for Legal Counsel to Make SEC Filings LIMITED POWER OF ATTORNEY FOR FILINGS UNDER THE SECURITIES ACT OF 1933, AS AMENDED AND THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED

EX-99.3 4 ea184525ex99-3neubase.htm POWER OF ATTORNEY OF ALETA SHIFF AUTHORIZING LEGAL COUNSEL TO CAUSE THIS SCHEDULE 13D TO BE FILED WITH THE SECURITIES AND EXCHANGE COMMISSION Exhibit 99.3 Aleta Shiff Power of Attorney for Legal Counsel to Make SEC Filings LIMITED POWER OF ATTORNEY FOR FILINGS UNDER THE SECURITIES ACT OF 1933, AS AMENDED AND THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED Know a

August 14, 2023 10-Q

3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents 3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended June 30, 2023 Or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to. Commission File Number 001-

August 11, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6

August 11, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permit

August 10, 2023 424B3

Up to 5,394,068 shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-273494 Prospectus Up to 5,394,068 shares of Common Stock Pursuant to this prospectus, the selling stockholders identified herein (the “Selling Stockholders”) are offering on a resale basis an aggregate of up to 5,394,068 shares of common stock of NeuBase Therapeutics, Inc. (the “Company,” “we,” “us” or “our”), par value $0.0001 per share (the “

August 7, 2023 CORRESP

NeuBase Therapeutics, Inc. 350 Technology Drive, Fourth Floor Pittsburgh, PA 15219

NeuBase Therapeutics, Inc. 350 Technology Drive, Fourth Floor Pittsburgh, PA 15219 August 7, 2023 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549-0406 Re: NeuBase Therapeutics, Inc. Registration Statement on Form S-1 Registration No. 333-273494 Ladies and Gentlemen: Pursuant to Rule 461 und

August 3, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 28, 2023 NeuBase Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 28, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

August 3, 2023 EX-99.1

NeuBase Therapeutics to Explore Strategic Alternatives

Exhibit 99.1 NeuBase Therapeutics to Explore Strategic Alternatives PITTSBURGH, August 3, 2023 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology company developing Stealth Editors™ to perform in vivo gene editing without triggering the immune system, today announced that its Board of Directors (the “Board”) has completed a review of the Company’s business, i

August 1, 2023 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permit

July 31, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 28, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

July 31, 2023 EX-10.1

AMendment NO. 1 to NEUBASE Therapeutics, INC. 2019 STOCK Incentive PLAN

Exhibit 10.1 AMendment NO. 1 to NEUBASE Therapeutics, INC. 2019 STOCK Incentive PLAN This Amendment No. 1 to the NeuBase Therapeutics, Inc. 2019 Stock Incentive Plan (this “Amendment”) is effective as of July 28, 2023. All capitalized terms in this Amendment, to the extent not otherwise defined herein, shall have the meaning assigned to them in the Plan (as defined below). Recitals Whereas, the Bo

July 28, 2023 S-1

As filed with the Securities and Exchange Commission on July 28, 2023

As filed with the Securities and Exchange Commission on July 28, 2023 Registration No.

July 28, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-1 (Form Type) NeuBase Therapeutics, Inc.

June 30, 2023 EX-99.2

NeuBase Announces Closing of $5 Million Concurrent Registered Direct Offering and Private Placement Priced At-the-Market Under Nasdaq Rules

Exhibit 99.2 NeuBase Announces Closing of $5 Million Concurrent Registered Direct Offering and Private Placement Priced At-the-Market Under Nasdaq Rules PITTSBURGH, June 30, 2023 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology company developing Stealth Editors™ to perform in vivo gene editing without triggering the immune system, today announced the closi

June 30, 2023 EX-4.5

Form of Placement Agent Common Stock Purchase Warrant.

Exhibit 4.5 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

June 30, 2023 EX-10.1

Securities Purchase Agreement, dated June 28, 2023 (Registered Direct Offering).

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of June 28, 2023, between NeuBase Therapeutics, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditio

June 30, 2023 424B5

187,700 Shares of Common Stock Pre-funded Warrants to Purchase up to 390,997 Shares of Common Stock Up to 390,997 Shares of Common Stock Underlying the Pre-funded Warrants

Filed Pursuant to Rule 424(b)(5) Registration No. 333-254980 PROSPECTUS SUPPLEMENT (To prospectus dated April 14, 2021) 187,700 Shares of Common Stock Pre-funded Warrants to Purchase up to 390,997 Shares of Common Stock Up to 390,997 Shares of Common Stock Underlying the Pre-funded Warrants We are offering (i) 187,700 shares of our common stock, $0.0001 par value per share, and (ii) Pre-funded War

June 30, 2023 EX-99.1

NeuBase Announces $5 Million Concurrent Registered Direct Offering and Private Placement Priced At-the-Market Under Nasdaq Rules

Exhibit 99.1 NeuBase Announces $5 Million Concurrent Registered Direct Offering and Private Placement Priced At-the-Market Under Nasdaq Rules PITTSBURGH, June 28, 2023 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology company developing Stealth Editors™ to perform in vivo gene editing without triggering the immune system, today announced that it has entered

June 30, 2023 EX-4.4

Form of Pre-Funded Common Stock Purchase Warrant (PIPE Private Placement).

Exhibit 4.4 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

June 30, 2023 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 28, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

June 30, 2023 EX-4.3

Form of Pre-Funded Common Stock Purchase Warrant (Registered Direct Offering).

Exhibit 4.3 PRE-FUNDED COMMON STOCK PURCHASE WARRANT NEUBASE THERAPEUTICS, INC. Warrant Shares: Issue Date: June 30, 2023 Initial Exercise Date: June 30, 2023 THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth,

June 30, 2023 EX-4.1

Form of Series A Common Stock Purchase Warrant.

Exhibit 4.1 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

June 30, 2023 EX-4.2

Form of Series B Common Stock Purchase Warrant.

Exhibit 4.2 NEITHER THIS SECURITY NOR THE SECURITIES FOR WHICH THIS SECURITY IS EXERCISABLE HAVE BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTR

June 30, 2023 424B3

293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-254980 SUPPLEMENT NO. 1 TO PROSPECTUS SUPPLEMENT DATED DECEMBER 29, 2022 (to Prospectus dated April 14, 2021) 293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock This Supplement No. 1 to Prospectus Supplement (this “Supplement No. 1”) amends and supplements the information in the prospectus, dated April 14, 2021 (the “Pro

June 30, 2023 EX-10.2

Securities Purchase Agreement, dated June 28, 2023 (PIPE Private Placement).

Exhibit 10.2 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of June 28, 2023, between NeuBase Therapeutics, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”). WHEREAS, subject to the terms and conditio

June 30, 2023 EX-10.3

Registration Rights Agreement, dated June 28, 2023.

Exhibit 10.3 REGISTRATION RIGHTS AGREEMENT This Registration Rights Agreement (this “Agreement”) is made and entered into as of June 28, 2023, by and between NeuBase Therapeutics, Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”). This Agreement is made pursuant to the Securitie

June 14, 2023 EX-99.1

NeuBase Announces 1-for-20 Reverse Stock Split

Exhibit 99.1 NeuBase Announces 1-for-20 Reverse Stock Split PITTSBURGH, June 14, 2023 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology company developing Stealth Editors™ to perform in vivo gene editing without triggering the immune system, today announced that it will effect a reverse stock split of its outstanding shares of common stock at a ratio of 1-fo

June 14, 2023 EX-3.1

Certificate of Amendment to the Amended and Restated Certificate of Incorporation of NeuBase Therapeutics, Inc., filed with the Secretary of State of the State of Delaware on June 14, 2023.

Exhibit 3.1 CERTIFICATE OF AMENDMENT TO THE AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF NEUBASE THERAPEUTICS, INC. NeuBase Therapeutics, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Corporation”), DOES HEREBY CERTIFY: FIRST: The name of the Corporation is NeuBase Therapeutics, Inc. SECOND: The original Certificate of Incorporation of the Corpora

June 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 14, 2023 NeuBase Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 14, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

June 5, 2023 10-QT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QT

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-QT ☐ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended Or ☒ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from October 1, 2022 to December 31, 2022. Commission File

May 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 22, 2023 NeuBase Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 22, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 22, 2023 EX-99.1

Safe Harbor Statement Certain statements contained in this presentation regarding matters that are not historical facts are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Priva

Exhibit 99.1 NEUBASE THERAPEUTICS, INC. The Future of Gene Editing is Stealth Editing™ Investor Conference Call | May 22, 2023 Safe Harbor Statement Certain statements contained in this presentation regarding matters that are not historical facts are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigatio

May 22, 2023 EX-99.2

NeuBase Announces Positive Preclinical Data Supporting the Capabilities of Stealth Editors™

Exhibit 99.2 NeuBase Announces Positive Preclinical Data Supporting the Capabilities of Stealth Editors™ - Data show that Stealth Editors™ achieve ex vivo gene editing using simple synthetic reagents to harness the cell's own high-fidelity editing machinery - Data show that Stealth Editors™ do not elicit a cell-based immunity and promise a non-immunogenic in vivo solution - Data show that Stealth

May 18, 2023 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 12, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 11, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 11, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 11, 2023 10-Q

3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents 3………………. UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended March 31, 2023 Or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to. Commission File Number 001

May 11, 2023 EX-99.1

NeuBase Reports Business Update and Financial Results for the First Quarter of 2023 Announced oral presentations at the American Society of Gene & Cell Therapy (“ASGCT”) 26th Annual Meeting to take place on May 16-20, 2023 Company to present addition

Exhibit 99.1 NeuBase Reports Business Update and Financial Results for the First Quarter of 2023 Announced oral presentations at the American Society of Gene & Cell Therapy (“ASGCT”) 26th Annual Meeting to take place on May 16-20, 2023 Company to present additional data showcasing gene editing capabilities at scientific conferences throughout remainder of 2023 PITTSBURGH, May 11, 2023 - NeuBase Th

April 24, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 21, 2023 NeuBase Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 21, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

March 29, 2023 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 29, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

March 16, 2023 CORRESP

Chief Financial Officer (Principal Financial and Accounting Officer)

March 16, 2023 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Jenn Do Kevin Vaughn Re: NeuBase Therapeutics, Inc. Form 10-K for Fiscal Year Ended September 30, 2022 Filed December 21, 2022 File No. 1-35963 Ladies and Gentlemen: This letter is submitted on behalf of NeuBase Therapeutics,

March 6, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) NeuBase Therapeutics, Inc.

March 6, 2023 S-8

As filed with the Securities and Exchange Commission on March 6, 2023

As filed with the Securities and Exchange Commission on March 6, 2023 Registration No.

February 14, 2023 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for the First Quarter of Fiscal Year 2023

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for the First Quarter of Fiscal Year 2023 PITTSBURGH, February 14, 2023 – NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology platform company Drugging the Genome™ to address disease at the base level using a new class of precision genetic medicines, today reported its financial resu

February 14, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended December 31, 2022 Or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to. Commission File Number 001-35963

February 14, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ___________________ FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 14,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 14, 2023 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

January 27, 2023 SC 13G/A

NBSE / Neubase Therapeutics Inc / Kershner Trading Americas,LLC - KTA NBSE 13G AMEND Passive Investment

SC 13G/A 1 nbse13g-amend2.htm KTA NBSE 13G AMEND UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* NeuBase Therapeutics, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 64132K102 (CUSIP Number) December 29, 2022 (Date of Event which Requires Filing of this Statement) Check the appropri

January 27, 2023 SC 13G/A

NBSE / Neubase Therapeutics Inc / Kershner Trading Americas,LLC - KTA NBSE 13G AMEND Passive Investment

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December 29, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 28, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 29, 2022 EX-10.1

Purchase Agreement, dated December 28, 2022, by and between NeuBase Therapeutics, Inc. and Alumni Capital LP

EX-10.1 2 tm2233671d1ex10-1.htm EXHIBIT 10.1   Exhibit 10.1   PURCHASE AGREEMENT   PURCHASE AGREEMENT (the “Agreement”), dated as of December 28, 2022, by and between NEUBASE THERAPEUTICS, INC., a Delaware corporation (the “Company”), and ALUMNI CAPITAL LP, a Delaware limited partnership (the “Investor”).   RECITALS   WHEREAS, subject to the terms and conditions set forth in this Agreement, the Co

December 29, 2022 424B5

293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock

424B5 1 tm2233672d1424b5.htm 424B5 Filed Pursuant to Rule 424(b)(5) Registration No. 333-254980 PROSPECTUS SUPPLEMENT (to Prospectus dated April 14, 2021) 293,398 Shares of Common Stock Up to $10,000,000 of Shares of Common Stock This prospectus supplement relates to the issuance and sale, from time to time, of up to ten million dollars ($10,000,000) in shares of the common stock, par value $0.000

December 21, 2022 EX-21.1

List of Subsidiaries of NeuBase Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries of NeuBase Therapeutics, Inc. 1. NeuBase Corporation (incorporated in Delaware) 2. Ohr Opco, Inc. (incorporated in Delaware) 3. Ohr Pharma, LLC (organized in Delaware)

December 21, 2022 EX-10.5

Amendment #1 to License Agreement, dated January 1, 2022, by and between NeuBase Therapeutics, Inc. and Carnegie Mellon University.

Exhibit 10.5 *** Certain information in this document has been excluded pursuant to Regulation S-K, Item 601(b)(10). Such excluded information is not material and is the type the registrant treats as confidential. Such omitted information is indicated by brackets “[***]”) in this exhibit. *** AMENDMENT #1 TO LICENSE AGREEMENT This Amendment #1 to the License Agreement (hereinafter this “Amendment”

December 21, 2022 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2022

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2022 PITTSBURGH, December 21, 2022 ? NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (?NeuBase? or the ?Company?), a biotechnology platform company Drugging the Genome? to address disease at the base level using a new class of precision genetic medicines, today reported its financial results for the fiscal ye

December 21, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 21, 2022 NeuBase Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 21, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 21, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Fiscal Year Ended September 30, 2022 or ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to Commission File Number 001-35963 NEUBASE

October 24, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 18, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

October 14, 2022 EX-99.1

NeuBase Therapeutics Announces Strategic Restructuring Focused on Advancing Its Platform in Gene Editing

Exhibit 99.1 NeuBase Therapeutics Announces Strategic Restructuring Focused on Advancing Its Platform in Gene Editing ? Workforce reductions of ~60% and implementation of a robust cost reduction plan are expected to extend the Company?s cash runway into Q2 CY2024 ? The Company plans to maximize shareholder value by focusing R&D resources on advancement of the differentiated gene editing capabiliti

October 14, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 7, 2022 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35963 46-5622433 (State or other jurisdiction of incorporation) (Commis

October 3, 2022 8-K

Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 29, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Comm

September 12, 2022 8-K

Financial Statements and Exhibits, Other Events, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 8, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

September 12, 2022 EX-10.1

NeuBase Therapeutics, Inc. Outside Director Compensation Policy.

Exhibit 10.1 NeuBase Therapeutics, Inc. OUTSIDE DIRECTOR COMPENSATION POLICY Most Recently Amended Effective as of September 8, 2022 NeuBase Therapeutics, Inc. (the ?Company?) believes that the granting of equity and cash compensation to its members of the Board of Directors (the ?Board,? and members of the Board, the ?Directors?) represents an effective tool to attract, retain and reward Director

August 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 11, 2022 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for the Third Quarter of Fiscal Year 2022

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for the Third Quarter of Fiscal Year 2022 ? Lead myotonic dystrophy type 1 (DM1) candidate continues to show promising preclinical data, including the pharmacokinetics (PK) and biodistribution data presented at the American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting supporting a differentiated whole-b

August 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 11, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

July 22, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.?? ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? ? Preliminary Proxy Statement ? ? Confidential, for Use of the Commission Only (as pe

July 22, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.?? ) Filed by the Registrant x Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6

July 12, 2022 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   )

PRE 14A 1 tm2220750-1pre14a.htm PRE 14A TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.   ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, f

June 29, 2022 EX-99.1

NeuBase Therapeutics Announces Promotion of Dr. William Mann to President and COO

Exhibit 99.1 NeuBase Therapeutics Announces Promotion of Dr. William Mann to President and COO PITTSBURGH and CAMBRIDGE, Mass., June 29, 2022 ? NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (?NeuBase? or the ?Company?), a biotechnology platform company Drugging the Genome? to address disease at the base level using a new class of precision genetic medicines, today announced the promotion of William (B

June 29, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 23, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

May 12, 2022 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for the Second Quarter of Fiscal Year 2022

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for the Second Quarter of Fiscal Year 2022 ? Investigational New Drug (IND)-enabling studies continue to generate promising data that support further development of the company?s lead myotonic dystrophy type 1 (DM1) candidate; new preclinical data to be presented at the American Society of Gene and Cell Therapy (ASGCT)

May 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 12, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 12, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

April 8, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) NeuBase Therapeutics, Inc.

April 8, 2022 S-8

As filed with the Securities and Exchange Commission on April 8, 2022

As filed with the Securities and Exchange Commission on April 8, 2022 Registration No.

March 14, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 14, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

March 14, 2022 EX-99.2

NeuBase Therapeutics Presents New Preclinical Data at MDA 2022 for Its Myotonic Dystrophy Type 1 Program Demonstrating Splice Rescue, Nuclear Aggregate Resolution, and Myotonia Reversal

Exhibit 99.2 NeuBase Therapeutics Presents New Preclinical Data at MDA 2022 for Its Myotonic Dystrophy Type 1 Program Demonstrating Splice Rescue, Nuclear Aggregate Resolution, and Myotonia Reversal ? A single intravenous dose of NeuBase?s Myotonic Dystrophy Type 1 (DM1) development candidate, NT-0231.F, potently rescues splicing, restores chloride channel (Clcn1) function, and durably reverses my

March 14, 2022 EX-99.1

1 NEUBASE THERAPEUTICS, INC. Drugging the Genome Œ with Precision Genetic Medicines Investor Update for Myotonic Dystrophy, Type 1 (DM1) Program March 14, 2022

Exhibit 99.1 1 NEUBASE THERAPEUTICS, INC. Drugging the Genome ? with Precision Genetic Medicines Investor Update for Myotonic Dystrophy, Type 1 (DM1) Program March 14, 2022 2 NEUBASE THERAPEUTICS, INC. Safe Harbor Statement Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking statements within the meaning of Section 21E of the Secu

February 14, 2022 SC 13G/A

NBSE / Neubase Therapeutics Inc / GREENLIGHT CAPITAL INC - AMENDMENT NO. 2 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* NeuBase Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 64132K102 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate

February 11, 2022 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for the First Quarter of Fiscal Year 2022

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for the First Quarter of Fiscal Year 2022 ? Investigational New Drug (IND)-enabling studies for the myotonic dystrophy type 1 (DM1) program development candidate continue as planned; invited to present new rodent pharmacokinetic (PK) and bioavailability data in an oral presentation at an upcoming scientific meeting; ex

February 11, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 10, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

February 11, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

January 10, 2022 EX-99.1

NeuBase Therapeutics Appoints Todd P. Branning Chief Financial Officer

Exhibit 99.1 NeuBase Therapeutics Appoints Todd P. Branning Chief Financial Officer PITTSBURGH and CAMBRIDGE, Mass., Jan. 10, 2022 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology platform company Drugging the Genome? to address disease at the base level using a new class of precision genetic medicines, announced today the appointment of Todd P. Branning as

January 10, 2022 EX-10.1

Offer Letter of Employment, dated January 10, 2022, by and between NeuBase Therapeutics, Inc. and Todd Branning.

Exhibit 10.1 January 3, 2022 Todd Branning, MBA via email to [email protected] Re: Offer Letter of Employment Dear Mr. Branning: I am very pleased to confirm our offer to you of full-time employment with NeuBase Therapeutics, Inc. (the ?Company?) in the position of Chief Financial Officer. Your effective start date will be mutually decided, but our hope is that you are able to join the Company o

January 10, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 10, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

January 5, 2022 EX-99.1

NeuBase Therapeutics Appoints Dr. Eric J. Ende to Board of Directors

Exhibit 99.1 NeuBase Therapeutics Appoints Dr. Eric J. Ende to Board of Directors PITTSBURGH and CAMBRIDGE, Mass., Jan. 5, 2022 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology platform company Drugging the Genome? to address disease at the base level using a new class of precision genetic medicines, announced today the appointment of Eric J. Ende, M.D., to

January 5, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 1, 2022 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

December 23, 2021 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

December 23, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 23, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 23, 2021 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2021

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2021 ? Validated ability to Drug the Genome? to address both rare and common diseases without the limitations of early precision genetic medicine technologies; the Company?s delivery shuttle enables pharmacology across programs in multiple tissues, including in the brain and muscle, after subcutaneous a

December 23, 2021 EX-21.1

List of Subsidiaries of NeuBase Therapeutics, Inc.

Exhibit 21.1 ? List of Subsidiaries of NeuBase Therapeutics, Inc. ? 1. NeuBase Corporation (incorporated in Delaware) 2. Ohr Opco, Inc. (incorporated in Delaware) 3. Ohr Pharma, LLC (organized in Delaware)

October 22, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 22, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commis

October 1, 2021 EX-10.1

Separation Agreement and General Release, dated September 30, 2021, by and between Sam Backenroth and NeuBase Therapeutics, Inc.

Exhibit 10.1 Separation Agreement and General Release In order to settle as fully as possible all known and unknown claims Sam Backenroth (?Employee?) might have against NeuBase Therapeutics, Inc. (the ?Company?) and all related parties, the Company and the Employee agree to the terms and conditions of this Separation Agreement and General Release (the ?Agreement?) as of the Effective Date. The Em

October 1, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 30, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Comm

August 27, 2021 424B5

Up to $50,000,000 Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-254980 PROSPECTUS SUPPLEMENT (To Prospectus dated April 14, 2021) Up to $50,000,000 Shares of Common Stock We have entered into an Open Market Sale AgreementSM, or the Sales Agreement, with Jefferies LLC, or Jefferies, dated August 27, 2021, relating to the sale of shares of our common stock, $0.0001 par value per share, offered by this prospec

August 27, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 27, 2021 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35963 46-5622433 (State or other jurisdiction of incorporation) (Commis

August 27, 2021 EX-1.1

Open Market Sale AgreementSM dated August 27, 2021, by and between NeuBase Therapeutics, Inc. and Jefferies LLC

Exhibit 1.1 OPEN MARKET SALE AGREEMENTSM August 27, 2021 JEFFERIES LLC 520 Madison Avenue New York, New York 10022 Ladies and Gentlemen: NeuBase Therapeutics, Inc., a Delaware corporation (the ?Company?), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the ?Agent?), shares of the Company?s comm

August 19, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 18, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

August 13, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of Contents ? ? UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 12, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 tm2124930d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 10, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisd

August 12, 2021 EX-99.1

NeuBase Therapeutics Reports Financial Results for the Third Quarter of Fiscal Year 2021 and Recent Operating Highlights

EX-99.1 2 tm2124930d1ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the Third Quarter of Fiscal Year 2021 and Recent Operating Highlights · Further demonstrated broad potential of novel genetic medicine platform with in vivo data in three diseases driven by different genetic mechanisms of disease · Presented preclinical data showing compounds enabled with N

July 7, 2021 424B3

NeuBase Therapeutics, Inc. 308,635 Shares of Common Stock

Filed Pursuant to Rule 424(b)(3) Registration No. 333-257327 PROSPECTUS NeuBase Therapeutics, Inc. 308,635 Shares of Common Stock This prospectus relates solely to the resale from time to time by the selling stockholder listed in the section of this prospectus entitled ?Selling Stockholder? (the ?Selling Stockholder?) of up to 308,635 shares (the ?Shares?) of our common stock, par value $0.0001 pe

July 2, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? ? Definitive Proxy Statement ? ?

July 2, 2021 CORRESP

NeuBase Therapeutics, Inc. 350 Technology Drive Pittsburgh, PA 15219

NeuBase Therapeutics, Inc. 350 Technology Drive Pittsburgh, PA 15219 July 2, 2021 VIA EDGAR Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549-0406 Re: NeuBase Therapeutics, Inc. Registration Statement on Form S-3, filed June 23, 2021 File No. 333-257327 Ladies and Gentlemen: Pursuant to Rule 461 under the Securities Act of 1933, as amended, NeuBase Therapeutics, Inc. (the

July 2, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Definitive Proxy Statement x Definitive Additional M

June 23, 2021 S-3

As filed with the Securities and Exchange Commission on June 23, 2021

S-3 1 tm2120228d1s3.htm FORM S-3 As filed with the Securities and Exchange Commission on June 23, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 NEUBASE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation o

June 23, 2021 EX-4.5

Form of Warrant

Exhibit 4.5 COMMON STOCK PURCHASE WARRANT NEUBASE THERAPEUTICS, INC. Warrant Shares: Issue Date: July , 2020 Initial Exercise Date: August , 2020 THIS COMMON STOCK PURCHASE WARRANT (the ?Warrant?) certifies that, for value received, or its assigns (the ?Holder?) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after

June 8, 2021 EX-99.2

Ultra - precision genetic medicines R&D DAY 2021 Drugging the genome to increase, decrease, or edit protein function to address base causality in disease

Exhibit 99.2 Ultra - precision genetic medicines R&D DAY 2021 Drugging the genome to increase, decrease, or edit protein function to address base causality in disease 2 2021 NeuBase Therapeutics, Inc. All Rights Reserved CAUTIONARY STATEMENT REGARDING FORWARD - LOOKING STATEMENTS Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking

June 8, 2021 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 8, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

June 8, 2021 EX-99.1

NeuBase Therapeutics Demonstrates Functional Rescue in Myotonic Dystrophy Type 1 Model and Allele-Selective Inhibition of KRAS Mutations to Inhibit Tumor Growth

Exhibit 99.1 NeuBase Therapeutics Demonstrates Functional Rescue in Myotonic Dystrophy Type 1 Model and Allele-Selective Inhibition of KRAS Mutations to Inhibit Tumor Growth ? Data presented today at NeuBase?s R&D Day show functional rescue of myotonic dystrophy type 1 (DM1) phenotype in vivo after subcutaneous dosing; positions program to enter the clinic in CY 2022 ? Company also presented data

May 25, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

8-K 1 tm2117300d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 25, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdict

May 25, 2021 EX-10.1

Offer Letter of Employment, dated May 17, 2021, by and between NeuBase Therapeutics, Inc. and Kia Motesharei.

Exhibit 10.1 May 17, 2021 Kianoush Motesharei, Ph.D. via email Re: Offer Letter of Employment Dear Dr. Motesharei: I am very pleased to confirm our offer to you of full-time employment with NeuBase Therapeutics, Inc. (the ?Company?) in the position of Chief Business and Strategy Officer. Your effective start date will be mutually decided, but our hope is that you are able to join the Company on Ma

May 25, 2021 EX-99.1

NeuBase Therapeutics Appoints Dr. Kia Motesharei Chief Business and Strategy Officer Expansion of management team continues with addition of an industry leader with deep experience in business development, licensing, and strategy in the life-science

Exhibit 99.1 NeuBase Therapeutics Appoints Dr. Kia Motesharei Chief Business and Strategy Officer Expansion of management team continues with addition of an industry leader with deep experience in business development, licensing, and strategy in the life-science industry PITTSBURGH, May 25, 2021 ? NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology company accel

May 20, 2021 EX-99.1

NeuBase Therapeutics Appoints Dr. Sandra Rojas-Caro Chief Medical Officer Expansion of management team to support the Company’s advancement of its first drug candidate into clinical trials next year and growth of therapeutic pipeline

Exhibit 99.1 NeuBase Therapeutics Appoints Dr. Sandra Rojas-Caro Chief Medical Officer Expansion of management team to support the Company?s advancement of its first drug candidate into clinical trials next year and growth of therapeutic pipeline PITTSBURGH, May 20, 2021 ? NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology company accelerating the genetic revol

May 20, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 17, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 20, 2021 EX-10.1

Offer Letter of Employment, effective May 17, 2021, by and between NeuBase Therapeutics, Inc. and Sandra Rojas-Caro.

Exhibit 10.1 May 15, 2021 Sandra Rojas-Caro, MD via email to [email protected] Re: Offer Letter of Employment Dear Dr. Rojas-Caro: I am thrilled to confirm our offer to you of full-time employment with NeuBase Therapeutics, Inc. (the ?Company?) in the position of Chief Medical Officer. Your effective start date will be on May 24, 2021. Your principal place of employment will be in the Boston,

May 14, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended March 31, 2021 Or ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to . Commission File Number 333-88480 NEUBASE THERAPEUTIC

May 13, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 13, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 13, 2021 EX-99.1

NeuBase Therapeutics Reports Financial Results for the Second Quarter of Fiscal Year 2021

Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the Second Quarter of Fiscal Year 2021 ? Extended cash runway into CY2023 following completion of an equity financing from leading healthcare investors generating $42.6 million in net proceeds; supports advancing the Company?s lead program into the clinic and scaling of its precision genetic medicine pipeline ? Completed acquisition o

May 12, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

8-K 1 tm2115934d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 11, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter)  Delaware 001-35963 46-5622433 (State or Other Jurisdic

May 12, 2021 EX-99.1

NeuBase Therapeutics Appoints Gerald J. McDougall to Board of Directors

Exhibit 99.1 NeuBase Therapeutics Appoints Gerald J. McDougall to Board of Directors ? Professional dealmaker operating across the healthcare continuum to bring together key partners to translate scientific breakthroughs into commercial applications for the benefit of patients and society ? Creator and guide of strategic alliances, including TGen, MMRC, and CIRM, the drivers behind large-scale tra

April 30, 2021 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 29, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

April 27, 2021 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 21, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

April 27, 2021 EX-10.1

Second Amendment to Lease Agreement, dated April 21, 2021.

Exhibit 10.1 SECOND AMENDMENT TO LEASE AGREEMENT THIS SECOND AMENDMENT TO LEASE AGREEMENT (this ?Amendment?) is made as of this 21st day of April, 2021 (the ?Effective Date?), by and between 350 TECHNOLOGY DRIVE PARTNERS, LLC, a Pennsylvania limited liability company (?Landlord?), and NEUBASE THERAPEUTICS, INC., a Delaware corporation (?Tenant?). WITNESSETH: WHEREAS, Landlord and Tenant are partie

April 26, 2021 8-K

Financial Statements and Exhibits, Other Events

8-K 1 tm2114180-18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 26, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdi

April 26, 2021 EX-99.1

NeuBase Therapeutics Announces Closing of Public Offering and Full Exercise of Underwriters’ Option to Purchase Additional Shares

EX-99.1 2 tm2114180d1ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 NeuBase Therapeutics Announces Closing of Public Offering and Full Exercise of Underwriters’ Option to Purchase Additional Shares PITTSBURGH, PA, April 26, 2021 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE), (“NeuBase”), a biotechnology company accelerating the genetic revolution with a new class of precision genetic medicines, announced toda

April 23, 2021 424B5

PROSPECTUS SUPPLEMENT (to Prospectus dated April 14, 2021) 8,000,000 Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-254980 PROSPECTUS SUPPLEMENT (to Prospectus dated April 14, 2021) 8,000,000 Shares of Common Stock We are offering 8,000,000 shares of our common stock, $0.0001 par value per share, in this offering. Our common stock is listed on The Nasdaq Capital Market under the symbol “NBSE.” On April 20, 2021, the last reported sale price of our common sto

April 22, 2021 EX-1.1

Underwriting Agreement, dated as of April 22, 2021, by and among NeuBase Therapeutics, Inc. and RBC Capital Markets, LLC, Oppenheimer & Co. Inc. and Chardan Capital Markets LLC, as representatives of the underwriters named therein.

Exhibit 1.1 NeuBase Therapeutics, Inc. 8,000,000 Shares Common Stock ($0.0001 par value per share) UNDERWRITING AGREEMENT New York, New York April 22, 2021 RBC Capital Markets, LLC Oppenheimer & Co. Inc. Chardan Capital Markets LLC As Representatives of the several Underwriters c/o RBC Capital Markets, LLC 200 Vesey Street New York, New York 10281-8098 c/o Oppenheimer & Co. Inc. 85 Broad Street, F

April 22, 2021 8-K

Entry into a Material Definitive Agreement, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 22, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

April 22, 2021 EX-99.1

NeuBase Therapeutics Announces Pricing of $40 Million Public Offering of Common Stock

Exhibit 99.1 NeuBase Therapeutics Announces Pricing of $40 Million Public Offering of Common Stock PITTSBURGH, PA, April 22, 2021 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (?NeuBase?), a biotechnology company accelerating the genetic revolution with a new class of precision genetic medicines, announced today the pricing of an underwritten public offering of 8,000,000 shares of its common stock,

April 21, 2021 424B5

SUBJECT TO COMPLETION, DATED APRIL 21, 2021

Filed Pursuant to Rule 424(b)(5) Registration No. 333-254980 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying base prospectus are not an offer to sell these securities, a

April 12, 2021 CORRESP

-

NeuBase Therapeutics, Inc. 350 Technology Drive Pittsburgh, PA 15219 April 12, 2021 VIA EDGAR Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549-0406 Re: NeuBase Therapeutics, Inc. Registration Statement on Form S-3, Filed April 1, 2021 File No. 333-254980 Pursuant to Rule 461 under the Securities Act of 1933, as amended, NeuBase Therapeutics, Inc. (the ?Company?) hereby re

April 1, 2021 S-3

- FORM S-3

S-3 1 tm2111161d1s3.htm FORM S-3 As filed with the Securities and Exchange Commission on April 1, 2021 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 46-5622433 (State or other jurisdiction of inco

April 1, 2021 EX-4.4

Form of Indenture, between the Registrant and one or more trustees to be named

Exhibit 4.4 NEUBASE THERAPEUTICS, INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of , 20 Debt Securities Table of Contents Page Article 1 DEFINITIONS 1 Section 1.01 Definitions of Terms 1 Article 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 5 Section 2.01 Designation and Terms of Securities 5 Section 2.02 Form of Securities and Trustee?s Certificate 8 Sec

March 26, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 tm2111103d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 25, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdi

February 16, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* NeuBase Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.0001 per share (Title of Class of Securities) 64132K102 (CUSIP Number) Decembner 31, 2020 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designat

February 16, 2021 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G and/or 13D (including any and all amendments thereto) with respect to Common Stock, par value $0.0001 per share, of NeuBase Therapeutics, Inc., and further agree that this Joint

February 11, 2021 EX-10.2

First Amendment to Lease Agreement, dated December 28, 2020.

EX-10.2 2 tm215685d1ex10-2.htm EXHIBIT 10.2 Exhibit 10.2 FIRST AMENDMENT TO LEASE AGREEMENT THIS FIRST AMENDMENT TO LEASE AGREEMENT (this “Amendment”) is made as of this 28 day of December, 2020, by and between 350 TECHNOLOGY DRIVE PARTNERS, LLC, a Pennsylvania limited liability company (“Landlord”), and NEUBASE THERAPEUTICS, INC., a Delaware corporation (“Tenant”). WITNESSETH: WHEREAS, Landlord a

February 11, 2021 EX-99.1

NeuBase Therapeutics Reports Financial Results for the First Quarter of Fiscal Year 2021 Recently demonstrated single-dose intravenous administration of a PATrOL™-enabled compound resolves the causal genetic defect in myotonic dystrophy type 1 (DM1)

Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the First Quarter of Fiscal Year 2021 Recently demonstrated single-dose intravenous administration of a PATrOL™-enabled compound resolves the causal genetic defect in myotonic dystrophy type 1 (DM1) in transgenic animals; Company on course to move one program into clinical development in CY2022 Plans to host an R&D day in the first ha

February 11, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 11, 2021 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

February 11, 2021 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended December 31, 2020 Or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to . Commission File Number 333-88480 NEUBASE THERAPEU

January 11, 2021 S-8

- FORM S-8

As filed with the Securities and Exchange Commission on January 11, 2021 Registration No.

December 29, 2020 SC 13G/A

UNITED STATES SECURIFIES AN D EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G U nder the Securities Exchange Act of I 934 (Amendment No. I )*

UNITED STATES SECURIFIES AN D EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G U nder the Securities Exchange Act of I 934 (Amendment No. I )* NexBase Therapeutics, Inc. (Name of Issuer) Common (Title of Class of Secu ri ties) 64132Kl02 (CUSI P umber) December 4, 2020 (Date of Event Which Requires Filing of this Statement) Checm the appropriate box to designate the rule pursuant to which th

December 23, 2020 EX-21.1

List of Subsidiaries of NeuBase Therapeutics, Inc.

Exhibit 21.1 List of Subsidiaries of NeuBase Therapeutics, Inc. 1. NeuBase Corporation (incorporated in Delaware) 2. Ohr Opco, Inc. (incorporated in Delaware) 3. Ohr Pharma, LLC (organized in Delaware)

December 23, 2020 EX-99.1

NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2020 Data presented throughout 2020 have validated the potential of the PATrOL™ platform to develop highly targeted therapies that increase, decrease or change causal

Exhibit 99.1 NeuBase Therapeutics Reports Business Update and Financial Results for Fiscal Year 2020 Data presented throughout 2020 have validated the potential of the PATrOL™ platform to develop highly targeted therapies that increase, decrease or change causal protein function Plan to provide updates on development pipeline, including the myotonic dystrophy type 1 (DM1) and Huntington’s disease

December 23, 2020 EX-10.30

Lease Agreement, dated as of October 2, 2020, by and between NeuBase Therapeutics, Inc. and 350 Technology Drive Partners, LLC.

Exhibit 10.30 LEASE AGREEMENT BY AND BETWEEN 350 TECHNOLOGY DRIVE PARTNERS, LLC, a Pennsylvania limited liability company (“LANDLORD”) AND NEUBASE THERAPEUTICS, INC. a Delaware corporation (“TENANT”) TABLE OF CONTENTS Page ARTICLE I - LEASED PREMISES 1 1.1 Demise 1 1.2 Tenant's Pro Rata Share 2 1.3 Landlord's Work; Early Access 2 1.4 Completion of Landlord's Work and Tenant Improvements 2 ARTICLE

December 23, 2020 EX-10.26

Amendment No. 4 to Sublease Agreement, dated as of August 20, 2020.

Exhibit 10.26 AMENDMENT NO. 4 TO SUBLEASE AGREEMENT This Amendment No. 4 to Lease Agreement (this "Amendment") is made and entered into this 20th day of August, 2020, with an effective date of October 1, 2020 (the "Effective Date"), by and between StartUptown dba Avenu ("Tenant"), and NeuBase Therapeutics Inc. ("Subtenant"). Tenant has previously amended its lease agreement with Carnegie Mellon Un

December 23, 2020 EX-10.27

Amendment No. 5 to Sublease Agreement, dated as of September 25, 2020.

Exhibit 10.27 AMENDMENT NO. 5 TO SUBLEASE AGREEMENT This Amendment No. 5 to Lease Agreement (this "Amendment") is made and entered into this 25th day of September, 2020, with an effective date of October 1, 2020 (the “Effective Date”), by and between StartUptown dba Avenu ("Tenant"), and NeuBase Therapeutics Inc. ("Subtenant"). Tenant has previously amended its lease agreement with Carnegie Mellon

December 23, 2020 10-K

Annual Report - FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Fiscal Year Ended September 30, 2020 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to Commission File Number 333-88480 NEUBASE THERAPEUTICS, INC

December 23, 2020 8-K

Results of Operations and Financial Condition, Financial Statements and Exhibits - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 23, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 16, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 16, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 16, 2020 EX-99.2

NeuBase Therapeutics Announces Positive Preclinical In Vivo Data for PATrOL™-enabled Anti-gene for the Treatment of Myotonic Dystrophy Type 1 In vivo data after single-dose IV administration demonstrate engagement with DMPK mRNA and broad rescue of m

Exhibit 99.2 NeuBase Therapeutics Announces Positive Preclinical In Vivo Data for PATrOL™-enabled Anti-gene for the Treatment of Myotonic Dystrophy Type 1 In vivo data after single-dose IV administration demonstrate engagement with DMPK mRNA and broad rescue of mis-splicing across key transcripts. Findings provide support for hypothesized mechanism of action of anti-gene, which is designed to not

December 16, 2020 EX-99.1

December 16, 2020 Accelerating the genetic revolution using a new class of synthetic medicines An emerging pipeline: resolution of causality in myotonic dystrophy, type 1 (DM1) via a PATrOL™ - enabled therapy

Exhibit 99.1 December 16, 2020 Accelerating the genetic revolution using a new class of synthetic medicines An emerging pipeline: resolution of causality in myotonic dystrophy, type 1 (DM1) via a PATrOL™ - enabled therapy Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking statements within the meaning of Section 21E of the Securi

December 2, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 30, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commi

December 2, 2020 EX-10.1

Offer Letter of Employment, dated November 30, 2020, by and between NeuBase Therapeutics, Inc. and Curt Bradshaw

Exhibit 10.1 November 30, 2020 Curt Bradshaw, Ph.D. Re: Offer Letter of Employment Dear Dr. Bradshaw: I am very pleased to confirm our offer to you of full-time employment with NeuBase Therapeutics, Inc. (the “Company”) in the position of Chief Science Officer. Your effective start date will be mutually decided, but our hope is that you are able to join the Company on or before December 1, 2020. Y

December 2, 2020 EX-99.1

NeuBase Therapeutics Announces Appointment of Curt Bradshaw, Ph.D. as Chief Scientific Officer

Exhibit 99.1 NeuBase Therapeutics Announces Appointment of Curt Bradshaw, Ph.D. as Chief Scientific Officer PITTSBURGH, PA – December 2, 2020 – NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology company accelerating the genetic revolution using a new class of synthetic medicines, today announced the appointment of Curt Bradshaw, Ph.D., as its new Chief Scientif

October 6, 2020 8-K

Entry into a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 2, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

September 11, 2020 8-K

Financial Statements and Exhibits, Other Events

8-K 1 tm2030702d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 9, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Juri

September 11, 2020 EX-10.1

Outside Director Compensation Policy

Exhibit 10.1 NeuBase Therapeutics, Inc. OUTSIDE DIRECTOR COMPENSATION POLICY Most Recently Amended Effective as of September 9, 2020 (the “Effective Date”) NeuBase Therapeutics, Inc. (the “Company”) believes that the granting of equity and cash compensation to its members of the Board of Directors (the “Board,” and members of the Board, the “Directors”) represents an effective tool to attract, ret

August 13, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 13, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

August 13, 2020 EX-99.1

NeuBase Therapeutics Reports Financial Results for the Third Fiscal Quarter of 2020 Strong Pharmacokinetic and Pharmacodynamic Data Presented in March Validate Platform and Position Company for Scalable Output of Synthetic Precision Genetic Medicines

Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the Third Fiscal Quarter of 2020 Strong Pharmacokinetic and Pharmacodynamic Data Presented in March Validate Platform and Position Company for Scalable Output of Synthetic Precision Genetic Medicines Company Continues to Progress Candidates in Huntington’s Disease (HD) and Myotonic Dystrophy (DM1) PITTSBURGH, PA, August 13, 2020 – Neu

August 13, 2020 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended June 30, 2020 Or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to . Commission File Number 333-88480 NEUBASE THERAPEUTICS

August 13, 2020 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 12, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commiss

July 28, 2020 EX-10.1

Offer Letter of Employment, dated July 22, 2020, by and between NeuBase Therapeutics, Inc. and William Mann.

Exhibit 10.1 July 22, 2020 Dr. William Mann via email Re: Offer Letter of Employment Dr. William Mann: I am very pleased to confirm our offer to you of full-time employment with NeuBase Therapeutics, Inc. (the “Company”) in the position of Chief Operating Officer. Your effective start date will be mutually decided, but our hope is that you are able to join the Company on or before July 27th, 2020.

July 28, 2020 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Other Events

8-K 1 tm2025871d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 22, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdic

July 28, 2020 EX-99.1

NeuBase Therapeutics Strengthens Senior Management Team with Appointment of Industry Veteran William Mann, Ph.D., MBA as Chief Operating Officer

Exhibit 99.1 NeuBase Therapeutics Strengthens Senior Management Team with Appointment of Industry Veteran William Mann, Ph.D., MBA as Chief Operating Officer PITTSBURGH, PA – July 28, 2020 – NeuBase Therapeutics, Inc. (Nasdaq: NBSE) ("NeuBase" or the "Company"), a biotechnology company developing next-generation antisense oligonucleotide (ASO) therapies using its scalable PATrOL™ platform to addre

July 1, 2020 DEFA14A

- DEFA14A

DEFA14A 1 tm2023902-2defa14a.htm DEFA14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A INFORMATION PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as pe

July 1, 2020 DEF 14A

- DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy State

June 9, 2020 8-K

Other Events

8-K 1 tm2022163-18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 8, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdict

May 14, 2020 EX-99.1

- - - Announced positive preclinical data that validates the key advantages of the proprietary NeuBase peptide-nucleic acid antisense oligonucleotide (PATrOL™) platform - - - Completed a public offering with net proceeds of approximately $33.3 millio

Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the Second Fiscal Quarter of 2020 - - - Announced positive preclinical data that validates the key advantages of the proprietary NeuBase peptide-nucleic acid antisense oligonucleotide (PATrOL™) platform - - - Completed a public offering with net proceeds of approximately $33.3 million in April 2020, strengthening the Company’s balance

May 14, 2020 10-Q

Quarterly Report - FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended March 31, 2020 Or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to . Commission File Number 333-88480 NEUBASE THERAPEUTIC

May 14, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 14, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commission

May 1, 2020 SC 13G/A

NBSE / NeuBase Therapeutics, Inc. / HIRSCHMAN ORIN - AMENDMENT TO FORM SC 13G Passive Investment

SC 13G/A 1 nbse-sc13ga071219.htm AMENDMENT TO FORM SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Schedule 13G/A (Amendment No. 4) (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934 NEUBASE THERAPEUTICS, INC . - (Name of I

April 30, 2020 EX-99.1

NeuBase Therapeutics Announces Closing of Public Offering and Full Exercise of Underwriters' Option to Purchase Additional Shares

Exhibit 99.1 NeuBase Therapeutics Announces Closing of Public Offering and Full Exercise of Underwriters' Option to Purchase Additional Shares PITTSBURGH, PA, April 30, 2020 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE), a preclinical-stage biotechnology company focused on developing next generation therapies to treat rare genetic diseases caused by mutant genes, announced today the closing of its p

April 30, 2020 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 30, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

April 29, 2020 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 28, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

April 29, 2020 424B5

5,250,000 Shares of Common Stock

Filed Pursuant to Rule 424(b)(5) Registration No. 333-220487 PROSPECTUS SUPPLEMENT (to Prospectus dated September 27, 2017) 5,250,000 Shares of Common Stock We are offering 5,250,000 shares of our common stock, $0.0001 par value per share, in this offering. Our common stock is listed on The Nasdaq Capital Market under the symbol “NBSE.” On April 27, 2020, the last reported sale price of our common

April 29, 2020 EX-1.1

Underwriting Agreement, dated as of April 28, 2020, by and between NeuBase Therapeutics, Inc. and Oppenheimer & Co. Inc. and BTIG, LLC, as representatives of the underwriters named therein.

Exhibit 1.1 NeuBase Therapeutics, Inc. (a Delaware corporation) 5,250,000 Shares of Common Stock UNDERWRITING AGREEMENT April 28, 2020 Oppenheimer & Co. Inc. BTIG, LLC As Representatives of the several Underwriters c/o Oppenheimer & Co. Inc. 85 Broad Street, Floor 23 New York, NY 10004 c/o BTIG, LLC 65 East 55th Street New York, NY, 10022 Ladies and Gentlemen: NeuBase Therapeutics, a Delaware corp

April 29, 2020 EX-99.1

NeuBase Therapeutics Announces Pricing of $31,500,000 Public Offering of Common Stock

Exhibit 99.1 NeuBase Therapeutics Announces Pricing of $31,500,000 Public Offering of Common Stock PITTSBURGH, PA, April 28, 2020 - NeuBase Therapeutics, Inc. (Nasdaq: NBSE), a preclinical-stage biotechnology company focused on developing next generation therapies to treat rare genetic diseases caused by mutant genes, announced today the pricing of an underwritten public offering of 5,250,000 shar

April 27, 2020 424B5

Subject to Completion, Dated April 27, 2020

Filed Pursuant to Rule 424(b)(5) Registration No. 333-220487 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been declared effective by the Securities and Exchange Commission. This preliminary prospectus supplement and the accompanying base prospectus are not an offer to sell these securities, a

April 3, 2020 EX-99.2

NeuBase Therapeutics Announces Positive, Preclinical Data Validating its Novel Genetic Therapy PATrOL™ Platform Demonstrates broad biodistribution, including across the blood-brain barrier into the central nervous system, and into skeletal muscle, in

Exhibit 99.2 NeuBase Therapeutics Announces Positive, Preclinical Data Validating its Novel Genetic Therapy PATrOL™ Platform Demonstrates broad biodistribution, including across the blood-brain barrier into the central nervous system, and into skeletal muscle, in non-human primates (“NHPs”) after systemic administration Durable and therapeutically relevant drug concentrations achieved in NHPs afte

April 3, 2020 EX-99.1

THE NEXT GENERATION OF ANTISENSE THERAPIES

Exhibit 99.1 THE NEXT GENERATION OF ANTISENSE THERAPIES 2 2020 NeuBase Therapeutics, Inc. All Rights Reserved CAUTIONARY STATEMENT REGARDING FORWARD - LOOKING STATEMENTS Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Priva

April 3, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 1, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissio

April 3, 2020 8-K/A

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 27, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Inco

April 3, 2020 EX-99.1

THE NEXT GENERATION OF ANTISENSE THERAPIES

Exhibit 99.1 THE NEXT GENERATION OF ANTISENSE THERAPIES 2 2020 NeuBase Therapeutics, Inc. All Rights Reserved CAUTIONARY STATEMENT REGARDING FORWARD - LOOKING STATEMENTS Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Priva

March 31, 2020 EX-99.2

THE NEXT GENERATION OF ANTISENSE THERAPIES

Exhibit 99.2 THE NEXT GENERATION OF ANTISENSE THERAPIES 2 2020 NeuBase Therapeutics, Inc. All Rights Reserved CAUTIONARY STATEMENT REGARDING FORWARD - LOOKING STATEMENTS Certain statements contained in this presentation regarding matters that are not historical facts are forward - looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Priva

March 31, 2020 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 27, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

March 31, 2020 EX-99.1

NeuBase Therapeutics Announces Positive, Preclinical Data Validating its Novel Genetic Therapy PATrOL™ Platform Demonstrates broad biodistribution, including across the blood-brain barrier into the central nervous system, and into skeletal muscle, in

Exhibit 99.1 NeuBase Therapeutics Announces Positive, Preclinical Data Validating its Novel Genetic Therapy PATrOL™ Platform Demonstrates broad biodistribution, including across the blood-brain barrier into the central nervous system, and into skeletal muscle, in non-human primates (“NHPs”) after systemic administration Durable and therapeutically relevant drug concentrations achieved in NHPs afte

March 26, 2020 EX-99.2

NEUBASE THERAPEUTICS, INC. INDEX TO FINANCIAL STATEMENTS

Exhibit 99.2 NEUBASE THERAPEUTICS, INC. INDEX TO FINANCIAL STATEMENTS Page Unaudited Balance Sheets as of December 31, 2018 (Restated) and September 30, 2018 2 Unaudited Statement of Operations for the three months ended December 31, 2018 (Restated) 3 Unaudited Statement of Stockholders Equity (Deficit) for the three months ended December 31, 2018 (Restated) 4 Unaudited Statement of Cash Flows for

March 26, 2020 EX-10.1

Lease Extension to Sublease Agreement, dated as of February 26, 2020, by and between NeuBase Therapeutics, Inc. and StartUptown dba Avenu.

Exhibit 10.1 February 26, 2020 Shannon Logan Chief of Staff and Operations Manager, NeuBase Therapeutics, Inc. 700 Technology Drive Pittsburgh, PA 15219 Re: Confirmation of lease extension Dear Shannon, NeuBase has the option to extend its current lease at 700 Technology Drive until September 30, 2020. All terms and conditions remain the same from the current lease as amended on July 29, 2019. Ple

March 26, 2020 8-K/A

Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 2) Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 12, 2019 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incor

March 26, 2020 10-Q

Our Quarterly Report on Form 10-Q for the quarter ended December 31, 2019, filed with the SEC on March 26, 2020

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended December 31, 2019 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from to . Commission File Number 333-88480 NEUBASE THERAPEU

March 26, 2020 EX-99.1

NeuBase Therapeutics Reports Financial Results for the First Fiscal Quarter of 2020 - - - NeuBase expects to announce pharmacokinetic data in non-human primates and in-vitro pharmacodynamic data for the PATrOL™ platform during the week of March 30th

Exhibit 99.1 NeuBase Therapeutics Reports Financial Results for the First Fiscal Quarter of 2020 - - - NeuBase expects to announce pharmacokinetic data in non-human primates and in-vitro pharmacodynamic data for the PATrOL™ platform during the week of March 30th as planned PITTSBURGH, PA, March 26, 2020 – NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”), a biotechnology compa

March 26, 2020 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 26, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of Incorporation) (Commissi

February 21, 2020 8-K

Regulation FD Disclosure, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 19, 2020 NeuBase Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 001-35963 46-5622433 (State or other jurisdiction of incorporation) (Commi

February 21, 2020 EX-99.1

NeuBase Therapeutics Receives Notification of Deficiency from Nasdaq Related to Delayed Quarterly Report on Form 10-Q

Exhibit 99.1 NeuBase Therapeutics Receives Notification of Deficiency from Nasdaq Related to Delayed Quarterly Report on Form 10-Q - - - Engaged Marcum LLP as its independent registered public accounting firm PITTSBURGH, Feb. 21, 2020 (GLOBE NEWSWIRE) - NeuBase Therapeutics, Inc. (Nasdaq: NBSE) (“NeuBase” or the “Company”) announced today that it received a standard notification letter dated Febru

February 18, 2020 8-K/A

Financial Statements and Exhibits, Changes in Registrant's Certifying Accountant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 9, 2020 NeuBase Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-35963 46-5622433 (State or Other Jurisdiction of In

February 18, 2020 EX-16.1

Letter from CohnReznick, LLP, dated February 18, 2020

Exhibit 16.1 February 18, 2020 Securities and Exchange Commission 100 F Street NE Washington, DC 20549 Ladies and Gentlemen: We have read the statements made by Neubase Therapeutics, Inc. (the “Company”), set forth in Item 4.01 of the Company’s Current Report on Form 8-K, dated February 13, 2020 (the “Form 8-K”). We agree with the statements concerning our Firm contained in such Item 4.01, except

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