Ionis Pharmaceuticals, Inc.
US ˙ NasdaqGS ˙ US4622221004

Introduction

This page provides a comprehensive analysis of the known insider trading history of Joseph H Wender. Insiders are officers, directors, or significant investors in a company. It is illegal for insiders to make trades in their companies based on specific, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4. Despite these restrictions, academic research suggests that insiders - in general - tend to outperform the market in their own companies.

Average Trade Profitability

The average trade profitability is the average return of all the open market purchases made by the insider in the last three years. To calculate this, we examine every open-market, unplanned purchase made by the insider, excluding all trades that were marked as part of a 10b5-1 trading plan. We then calculate the average performance of those trades over 3, 6, and 12 months, averaging each of those durations to generate a final performance metric for each trade. Finally, we average all of the performance metrics to calculate a performance metric for the insider. This list only includes insiders that have made at least three trades in the last two years.

If this insiders trade profitability is "N/A", then the insider either has not made any open-market purchases in the last three years, or the trades they’ve made are too recent to calculate a reliable performance metric.

Update Frequency: Daily

See the list of most profitable insider traders.

Companies with Reported Insider Positions

The SEC filings indicate Joseph H Wender has reported holdings or trades in the following companies:

Security Title Latest Reported Holdings
US:IONS / Ionis Pharmaceuticals, Inc. Director 108,835
US:OUT / OUTFRONT Media Inc. Director 69,996
How to Interpret the Charts

The following charts show the stock performance of securities subsequent to each open-market, non-planned trade made by Joseph H Wender. Non-planned trade are trades that were not made as part of a 10b5-1 trading plan. The stock performance is charted as cumulative percent change in share price. For example, if an insider trade was made on January 1, 2019, the chart will show the daily percent change of the security to the present day. If the share price were to go from $10 to $15 during this time, the cumulative percent change in share price would be 50%. A change in price from $10 to $20 would be 100%, and a change in price of $10 to $5 would be -50%.

Ultimately, we are trying to determine how closely the insider’s trades correlate to excess returns (positive or negative) in the share price in order to see if the insider is timing their trades to profit from insider information. Consider the situation where an insider was doing this. In this situation, we would expect either (a) positive returns after purchases, or (b) negative returns after sales. In the case of (a), the PURCHASE chart would show a series of upwardly sloping curves, indicating positive returns after each purchase transaction. In the case of (b), the SALE chart would show a series of downward sloping curves, indicating negative returns after each sale transaction.

However, this alone is not enough to draw conclusions. If, for example, the share price of the company was in a non-cyclical climb over many years, then we would expect all the post-purchase plots to be upwardly sloping. Likewise, non-cyclical declines over many years would result in downward sloping post-trade plots. Neither of these charts would suggest insider trading activity.

The strongest indicator would be a situation where the share price was extremely cyclical, and there were both positive signals in the PURCHASE chart and negative plots on the SALE chart. This situation would be highly suggestive of an insider that was timing trades to their financial advantage.

Insider Purchases IONS / Ionis Pharmaceuticals, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in IONS / Ionis Pharmaceuticals, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insider Sales IONS / Ionis Pharmaceuticals, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in IONS / Ionis Pharmaceuticals, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
2019-03-19 IONS WENDER JOSEPH H 10,000 79.6258 10,000 79.6258 796,258 363 43.2500 -363,758 -45.68
2018-05-11 IONS WENDER JOSEPH H 400 44.0200 400 44.0200 17,608
2018-05-11 IONS WENDER JOSEPH H 6,010 45.7900 6,010 45.7900 275,198
2018-05-11 IONS WENDER JOSEPH H 8,590 45.0300 8,590 45.0300 386,808
2015-03-18 ISIS WENDER JOSEPH H 6,100 70.9480 6,100 70.9480 432,783
2015-03-18 ISIS WENDER JOSEPH H 6,400 71.8443 6,400 71.8443 459,804
2015-03-05 ISIS WENDER JOSEPH H 12,500 71.6139 12,500 71.6139 895,174
2015-03-02 ISIS WENDER JOSEPH H 7,000 65.9693 7,000 65.9693 461,785
2015-02-12 ISIS WENDER JOSEPH H 10,000 62.1460 10,000 62.1460 621,460
2014-02-03 ISIS WENDER JOSEPH H 4,700 48.7825 4,700 48.7825 229,278
2014-01-22 ISIS WENDER JOSEPH H 10,000 50.9803 10,000 50.9803 509,803
2013-12-20 ISIS WENDER JOSEPH H 10,000 40.0125 10,000 40.0125 400,125
2013-12-19 ISIS WENDER JOSEPH H 9,731 39.1340 9,731 39.1340 380,813
2013-11-26 ISIS WENDER JOSEPH H 10,000 36.6336 10,000 36.6336 366,336
2013-06-20 ISIS WENDER JOSEPH H 5,447 20.9300 5,447 20.9300 114,006

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

IONS / Ionis Pharmaceuticals, Inc. Insider Trades
Insider Trading History

This table shows the complete list of insider trades made by Joseph H Wender as disclosed to the Securities Exchange Commission (SEC).

File Date Tran Date Form Ticker Security Code 10b5-1 Shares Remaining Shares Percent
Change
Share
Price
Tran
Value
Remaining
Value
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11,200 108,835 -9.33 60.14 -673,549 6,545,152
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5,600 120,035 -4.46 57.53 -322,174 6,905,746
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11,200 125,635 -8.19 55.04 -616,432 6,914,775
2025-09-04 2025-09-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11,200 108,835 -9.33 60.14 -673,549 6,545,152
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -5,600 120,035 -4.46 57.53 -322,174 6,905,746
2025-09-04 2025-09-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale X -11,200 125,635 -8.19 55.04 -616,432 6,914,775
2025-07-17 2025-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4,079 136,835 3.07
2025-06-05 2025-06-03 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 771 69,996 1.11
2025-06-05 2025-06-03 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 10,125 69,225 17.13
2024-07-17 2024-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4,677 132,756 3.65
2024-06-10 2024-06-06 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 624 59,356 1.06
2024-06-10 2024-06-06 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 9,863 58,732 20.18
2024-05-13 2024-05-09 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 16,000 128,079 14.28 35.53 568,480 4,550,647
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5,333 112,079 5.00
2023-07-19 2023-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1,777 106,746 1.69
2023-06-08 2023-06-07 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 576 48,869 1.19
2023-06-08 2023-06-07 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 7,290 48,293 17.78
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2,665 104,969 2.60
2022-07-19 2022-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5,333 102,304 5.50
2022-06-09 2022-06-08 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 201 41,003 0.49
2022-06-09 2022-06-08 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 4,907 40,802 13.67
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -1,778 9,775 -15.39
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -666 11,553 -5.45
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -889 12,219 -6.78
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
M - Exercise -5,333 13,108 -28.92
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1,778 96,971 1.87
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 95,193 0.70
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 94,527 0.95
2021-07-19 2021-07-15 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5,333 93,638 6.04
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Unit
A - Award 5,333 18,441 40.69
2021-07-06 2021-07-01 4 IONS IONIS PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy)
A - Award 12,000 12,000
2021-06-09 2021-06-08 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -6,366 0 -100.00
2021-06-09 2021-06-08 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 4,907 4,907
2021-06-09 2021-06-08 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 6,366 35,895 21.56
2020-09-18 2020-09-16 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -11,250 0 -100.00
2020-09-18 2020-09-16 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -11,250 0 -100.00
2020-09-18 2020-09-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 11,250 88,305 14.60 28.47 320,288 2,514,043
2020-09-18 2020-09-16 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 11,250 77,055 17.10 12.94 145,575 997,092
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50.04
2020-07-06 2020-07-06 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 65,805 1.02
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 1,777 -33.35
2020-07-06 2020-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 65,138 1.38
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 12,000 12,000
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 5,333 5,333
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1,778 5,332 -25.01
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100.00
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 1,778 64,249 2.85
2020-07-06 2020-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 62,471 1.08
2020-06-10 2020-06-10 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -4,610 0 -100.00
2020-06-10 2020-06-10 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 312 29,529 1.07
2020-06-10 2020-06-10 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 4,610 29,217 18.73
2020-06-10 2020-06-08 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 6,366 6,366
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 1,333 -33.35
2019-07-03 2019-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 61,805 1.09
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -889 2,666 -25.01
2019-07-03 2019-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 889 61,138 1.48
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 7,110 7,110
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 666 -50.04
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -666 0 -100.00
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 60,249 1.12
2019-07-03 2019-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 666 59,582 1.13
2019-06-11 2019-06-11 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -6,018 4,610 -56.62
2019-06-11 2019-06-11 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 254 24,607 1.04
2019-06-11 2019-06-11 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 6,018 24,353 32.82
2019-06-11 2019-06-10 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 4,610 10,628 76.60
2019-03-20 2019-03-19 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -10,000 58,916 -14.51 79.63 -796,258 4,691,234
2018-07-19 2018-07-17 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -15,000 0 -100.00
2018-07-19 2018-07-17 4 IONS IONIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -15,000 0 -100.00
2018-07-19 2018-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 15,000 68,916 27.82 9.30 139,500 640,919
2018-07-19 2018-07-17 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 15,000 53,916 38.54 9.22 138,300 497,106
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2,000 -25.01
2018-07-03 2018-07-03 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 38,916 1.74
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2018-07-03 2018-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 3,555 3,555
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2,000 1,999 -50.01
2018-07-03 2018-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2,000 38,249 5.52
2018-06-14 2018-06-12 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -5,307 0 -100.00
2018-06-14 2018-06-12 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 286 18,335 1.58
2018-06-14 2018-06-12 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 5,307 18,049 41.65
2018-06-13 2018-06-11 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 6,018 6,018
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -15,000 0 -100.00
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -8,590 36,249 -19.16 45.03 -386,808 1,632,292
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 8,590 44,839 23.70 13.88 119,229 622,365
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -6,010 36,249 -14.22 45.79 -275,198 1,659,842
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6,010 42,259 16.58 13.88 83,419 586,555
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
S - Sale -400 36,249 -1.09 44.02 -17,608 1,595,681
2018-05-11 2018-05-11 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 400 36,649 1.10 13.88 5,552 508,688
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2017-07-03 2017-07-03 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2,667 2,667
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -2,469 3,999 -38.17
2017-07-03 2017-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 2,469 36,249 7.31
2017-06-14 2017-06-12 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 5,307 5,307
2017-06-09 2017-06-07 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -5,183 0 -100.00
2017-06-09 2017-06-07 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 319 12,742 2.57
2017-06-09 2017-06-07 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 5,183 12,423 71.59
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 0 -100.00
2016-07-06 2016-07-02 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 33,780 0.93
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2,667 2,667
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -1,803 3,801 -32.17
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 33,468 1.42
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 32,999 2.06
2016-07-06 2016-07-01 4 IONS IONIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 32,999 2.06
2016-06-13 2016-06-09 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -4,461 0 -100.00
2016-06-13 2016-06-09 4 OUT OUTFRONT Media Inc.
Common Stock
A - Award 262 7,240 3.75
2016-06-13 2016-06-09 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 4,461 6,978 177.23
2016-06-09 2016-06-07 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 5,183 5,183
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -312 312 -50.00
2015-07-02 2015-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 312 31,665 1.00
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2,667 2,667
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -667 2,000 -25.01
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 937 -33.36
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 667 31,353 2.17
2015-07-02 2015-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 30,686 1.55
2015-06-11 2015-06-09 4 OUT OUTFRONT Media Inc.
Restricted Share Units
A - Award 4,461 4,461
2015-04-03 2015-03-28 4/A OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 2,438 2,517 3,086.08
2015-03-31 2015-03-28 4 OUT OUTFRONT Media Inc.
Restricted Share Units
M - Exercise -2,438 0 -100.00
2015-03-31 2015-03-28 4 OUT OUTFRONT Media Inc.
Common Stock
F - Taxes -913 1,604 -36.27 30.09 -27,472 48,264
2015-03-31 2015-03-28 4 OUT OUTFRONT Media Inc.
Common Stock
M - Exercise 2,438 2,517 3,086.08
2015-03-20 2015-03-18 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -12,500 0 -100.00
2015-03-20 2015-03-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -6,400 30,217 -17.48 71.84 -459,804 2,170,919
2015-03-20 2015-03-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6,400 36,617 21.18 5.93 37,952 217,139
2015-03-20 2015-03-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -6,100 30,217 -16.80 70.95 -432,783 2,143,836
2015-03-20 2015-03-18 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 6,100 36,317 20.19 5.93 36,173 215,360
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -12,500 0 -100.00
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -12,500 30,217 -29.26 71.61 -895,174 2,163,957
2015-03-09 2015-03-05 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 12,500 42,717 41.37 9.77 122,125 417,345
2015-03-04 2015-03-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -7,000 30,217 -18.81 65.97 -461,785 1,993,394
2015-02-17 2015-02-12 4 ISIS ISIS PHARMACEUTICALS INC
Non-Employee Director Stock Option (right to buy)
M - Exercise -10,000 0 -100.00
2015-02-17 2015-02-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10,000 37,217 -21.18 62.15 -621,460 2,312,888
2015-02-17 2015-02-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10,000 47,217 26.87 3.95 39,500 186,507
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 624 -33.40
2014-07-02 2014-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 37,217 0.85
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 16,000 16,000
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 2,667 2,667
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -469 1,406 -25.01
2014-07-02 2014-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 469 36,904 1.29
2014-04-01 2014-03-28 4 CBSO CBS OUTDOOR AMERICAS INC.
Restricted Share Units
A - Award 2,143 2,143
2014-02-07 2014-02-06 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -5,300 0 -100.00
2014-02-07 2014-02-06 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 5,300 36,435 17.02 5.72 30,316 208,408
2014-02-05 2014-02-03 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -4,700 5,300 -47.00
2014-02-05 2014-02-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -4,700 31,135 -13.12 48.78 -229,278 1,518,843
2014-02-05 2014-02-03 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 4,700 35,835 15.10 5.72 26,884 204,976
2014-01-24 2014-01-22 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10,000 31,135 -24.31 50.98 -509,803 1,587,272
2013-12-20 2013-12-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10,000 41,135 -19.56 40.01 -400,125 1,645,914
2013-12-20 2013-12-19 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -15,000 0 -100.00
2013-12-20 2013-12-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -9,731 51,135 -15.99 39.13 -380,813 2,001,117
2013-12-20 2013-12-19 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 15,000 60,866 32.70 16.32 244,800 993,333
2013-11-27 2013-11-26 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
S - Sale -10,000 45,866 -17.90 36.63 -366,336 1,680,237
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
M - Exercise -313 937 -25.04
2013-07-03 2013-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 313 55,866 0.56
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1,875 1,875
2013-07-03 2013-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11,250 11,250
2013-06-24 2013-06-20 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -10,000 0 -100.00
2013-06-24 2013-06-20 4 ISIS ISIS PHARMACEUTICALS INC
Common stock
S - Sale -5,447 55,553 -8.93 20.93 -114,006 1,162,724
2013-06-24 2013-06-20 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10,000 61,000 19.61 5.17 51,700 315,370
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 11,250 11,250
2012-07-03 2012-07-02 4 ISIS ISIS PHARMACEUTICALS INC
Restricted Stock Units
A - Award 1,250 1,250
2012-06-13 2012-06-12 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
M - Exercise -10,000 0 -100.00
2012-06-13 2012-06-12 4 ISIS ISIS PHARMACEUTICALS INC
Common Stock
M - Exercise 10,000 51,000 24.39 8.15 81,500 415,650
2005-07-06 2005-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 10,000 10,000
2004-07-02 2004-07-01 4 ISIS ISIS PHARMACEUTICALS INC
Director Stock Option (right to buy)
A - Award 10,000 10,000
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)