Voyager Therapeutics, Inc.
US ˙ NasdaqGS ˙ US92915B1061

Introduction

This page provides a comprehensive analysis of the known insider trading history of Steven M Paul. Insiders are officers, directors, or significant investors in a company. It is illegal for insiders to make trades in their companies based on specific, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4. Despite these restrictions, academic research suggests that insiders - in general - tend to outperform the market in their own companies.

Average Trade Profitability

The average trade profitability is the average return of all the open market purchases made by the insider in the last three years. To calculate this, we examine every open-market, unplanned purchase made by the insider, excluding all trades that were marked as part of a 10b5-1 trading plan. We then calculate the average performance of those trades over 3, 6, and 12 months, averaging each of those durations to generate a final performance metric for each trade. Finally, we average all of the performance metrics to calculate a performance metric for the insider. This list only includes insiders that have made at least three trades in the last two years.

If this insiders trade profitability is "N/A", then the insider either has not made any open-market purchases in the last three years, or the trades they’ve made are too recent to calculate a reliable performance metric.

Update Frequency: Daily

See the list of most profitable insider traders.

Companies with Reported Insider Positions

The SEC filings indicate Steven M Paul has reported holdings or trades in the following companies:

Security Title Latest Reported Holdings
Director 477,642
US:KRTX / Karuna Therapeutics, Inc. Director 0
US:SAGE / Sage Therapeutics, Inc. Director 78,539
US:ALNY / Alnylam Pharmaceuticals, Inc. Director 0
US:VYGR / Voyager Therapeutics, Inc. Director 15,000
US:SIAL / Sigma-Aldrich Corporation Director 0
How to Interpret the Charts

The following charts show the stock performance of securities subsequent to each open-market, non-planned trade made by Steven M Paul. Non-planned trade are trades that were not made as part of a 10b5-1 trading plan. The stock performance is charted as cumulative percent change in share price. For example, if an insider trade was made on January 1, 2019, the chart will show the daily percent change of the security to the present day. If the share price were to go from $10 to $15 during this time, the cumulative percent change in share price would be 50%. A change in price from $10 to $20 would be 100%, and a change in price of $10 to $5 would be -50%.

Ultimately, we are trying to determine how closely the insider’s trades correlate to excess returns (positive or negative) in the share price in order to see if the insider is timing their trades to profit from insider information. Consider the situation where an insider was doing this. In this situation, we would expect either (a) positive returns after purchases, or (b) negative returns after sales. In the case of (a), the PURCHASE chart would show a series of upwardly sloping curves, indicating positive returns after each purchase transaction. In the case of (b), the SALE chart would show a series of downward sloping curves, indicating negative returns after each sale transaction.

However, this alone is not enough to draw conclusions. If, for example, the share price of the company was in a non-cyclical climb over many years, then we would expect all the post-purchase plots to be upwardly sloping. Likewise, non-cyclical declines over many years would result in downward sloping post-trade plots. Neither of these charts would suggest insider trading activity.

The strongest indicator would be a situation where the share price was extremely cyclical, and there were both positive signals in the PURCHASE chart and negative plots on the SALE chart. This situation would be highly suggestive of an insider that was timing trades to their financial advantage.

Insider Purchases VYGR / Voyager Therapeutics, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in VYGR / Voyager Therapeutics, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
2016-01-14 VYGR PAUL STEVEN M 10,000 14.0690 10,000 14.0690 140,690 207 16.2600 21,910 15.57

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

VYGR / Voyager Therapeutics, Inc. Insider Trades
Insider Sales VYGR / Voyager Therapeutics, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in VYGR / Voyager Therapeutics, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

VYGR / Voyager Therapeutics, Inc. Insider Trades
Insider Trading History

This table shows the complete list of insider trades made by Steven M Paul as disclosed to the Securities Exchange Commission (SEC).

File Date Tran Date Form Ticker Security Code 10b5-1 Shares Remaining Shares Percent
Change
Share
Price
Tran
Value
Remaining
Value
2024-06-06 3 RAPP Rapport Therapeutics, Inc.
Common Stock
477,642
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -35,877 0 -100.00 330.00 -11,839,410
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -30,304 0 -100.00 330.00 -10,000,320
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -30,304 0 -100.00 330.00 -10,000,320
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -33,882 0 -100.00 330.00 -11,181,060
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -10,000 0 -100.00 330.00 -3,300,000
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -8,550 0 -100.00 330.00 -2,821,500
2024-03-18 2024-03-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
D - Sale to Issuer -2,046 8,550 -19.31 330.00 -675,180 2,821,500
2024-03-04 2024-03-04 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift 30,304 30,304
2024-03-04 2024-03-04 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift -30,304 2,364 -92.76
2024-03-04 2024-03-01 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift 30,304 32,668 1,281.90
2024-03-04 2024-03-01 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift 30,304 32,668 1,281.90
2024-03-04 2024-03-01 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift -30,304 10,000 -75.19
2024-03-04 2024-03-01 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift -30,304 10,000 -75.19
2024-03-04 2024-02-29 4 KRTX Karuna Therapeutics, Inc.
Common Stock
J - Other 47,378 70,608 203.95 315.18 14,932,598 22,254,229
2024-02-26 2024-02-23 4 KRTX Karuna Therapeutics, Inc.
Common Stock
M - Exercise 4,008 42,114 10.52 99.72 399,678 4,199,608
2024-02-26 2024-02-23 4 KRTX Karuna Therapeutics, Inc.
Common Stock
M - Exercise 27,510 38,106 259.63 7.27 199,998 277,031
2024-02-12 2024-02-09 4 KRTX Karuna Therapeutics, Inc.
Common Stock
F - Taxes -804 10,596 -7.05 317.14 -254,981 3,360,415
2023-02-13 2023-02-09 4 KRTX Karuna Therapeutics, Inc.
Common Stock
A - Award 11,400 11,400
2023-02-13 2022-05-31 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift 106,485 106,485
2023-02-13 2022-05-31 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift -106,485 0 -100.00
2023-02-13 2022-05-27 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift 106,485 106,485
2023-02-13 2022-05-27 4 KRTX Karuna Therapeutics, Inc.
Common Stock
G - Gift -106,485 0 -100.00
2022-11-30 2022-11-28 4 SAGE Sage Therapeutics, Inc.
Common Stock
J - Other 5 78,539 0.01 38.17 191 2,997,637
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy)
M - Exercise X -15,000 0 -100.00
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -175 1,000 -14.89 178.60 -31,255 178,600
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -825 1,175 -41.25 177.58 -146,504 208,656
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -526 2,000 -20.82 176.51 -92,844 353,020
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -90 2,526 -3.44 174.33 -15,690 440,358
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -642 2,616 -19.71 173.06 -111,105 452,725
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -1,434 3,258 -30.56 172.10 -246,791 560,702
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -1,235 4,692 -20.84 171.16 -211,383 803,083
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -4,872 5,927 -45.12 169.71 -826,827 1,005,871
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -4,948 10,799 -31.42 168.95 -835,965 1,824,491
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -253 15,747 -1.58 166.04 -42,008 2,614,632
2022-04-05 2022-04-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
M - Exercise X 15,000 16,000 1,500.00 11.33 169,950 181,280
2022-02-17 2022-02-16 4 KRTX Karuna Therapeutics, Inc.
Option (right to buy)
A - Award 146,900 146,900
2022-01-05 2022-01-04 4 SAGE Sage Therapeutics, Inc.
Stock Options (Right to buy)
A - Award 1,638 1,638
2021-11-12 2021-11-09 4 SAGE Sage Therapeutics, Inc.
Common Stock
J - Other 1 1 43.36 43 43
2021-08-18 2021-08-18 4 KRTX Karuna Therapeutics, Inc.
Common Stock
P - Purchase 1,181 108,849 1.10 106.10 125,304 11,548,879
2021-08-18 2021-08-17 4 KRTX Karuna Therapeutics, Inc.
Common Stock
P - Purchase 1,183 107,668 1.11 105.63 124,960 11,372,971
2021-07-19 2021-07-15 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 4,032 4,032
2021-06-11 2021-06-10 4 SAGE Sage Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 10,000 10,000
2021-06-04 2021-06-03 4 VYGR Voyager Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 15,000 15,000
2021-02-24 2021-02-23 4 KRTX Karuna Therapeutics, Inc.
Option (right to buy)
A - Award 161,850 161,850
2021-01-15 2020-03-31 5 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
G - Gift 292,207 292,207
2021-01-15 2020-03-31 5 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
G - Gift -292,207 0 -100.00
2021-01-15 2020-03-30 5 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
G - Gift 292,207 292,207
2021-01-15 2020-03-30 5 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
G - Gift -292,207 0 -100.00
2020-12-22 2020-12-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
M - Exercise X -15,000 0 -100.00
2020-12-22 2020-12-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -15,000 1,000 -93.75 140.00 -2,100,000 140,000
2020-12-22 2020-12-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
M - Exercise X 15,000 16,000 1,500.00 9.30 139,500 148,800
2020-07-06 2020-07-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 4,581 4,581
2020-06-30 2020-06-29 4 KRTX Karuna Therapeutics, Inc.
Option (right to buy)
M - Exercise -292,207 0 -100.00
2020-06-30 2020-06-29 4 KRTX Karuna Therapeutics, Inc.
Common Stock
S - Sale -292,207 106,485 -73.29 103.50 -30,243,424 11,021,198
2020-06-30 2020-06-29 4 KRTX Karuna Therapeutics, Inc.
Common Stock
M - Exercise 292,207 398,692 274.41 0.11 32,143 43,856
2020-06-11 2020-06-09 4 SAGE Sage Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 10,000 10,000
2020-06-05 2020-06-04 4 VYGR Voyager Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 15,000 15,000
2020-02-19 2020-02-14 4 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award -140,000 140,000 -50.00
2020-02-11 2020-02-10 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy)
M - Exercise X -30,000 0 -100.00
2020-02-11 2020-02-10 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
S - Sale X -30,000 1,000 -96.77 130.00 -3,900,000 130,000
2020-02-11 2020-02-10 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
M - Exercise X 30,000 31,000 3,000.00 14.67 440,100 454,770
2019-07-02 2019-07-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 9,000 9,000
2019-07-02 2019-07-02 4 KRTX Karuna Therapeutics, Inc.
Series A Preferred Stock
C - Conversion -74,294 0 -100.00
2019-07-02 2019-07-02 4 KRTX Karuna Therapeutics, Inc.
Common Stock
C - Conversion 96,485 106,485 964.85
2019-07-01 2019-06-28 4 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award -71,121 71,121 -50.00
2019-07-01 2019-06-28 4 KRTX Karuna Therapeutics, Inc.
Common Stock
P - Purchase 3,200 10,000 47.06 23.43 74,976 234,300
2019-07-01 2019-06-28 4 KRTX Karuna Therapeutics, Inc.
Common Stock
P - Purchase 6,800 6,800 22.86 155,448 155,448
2019-07-01 2019-06-27 4 KRTX Karuna Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award -616,703 616,703 -50.00
2019-06-17 2019-06-13 4 VYGR Voyager Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 15,000 15,000
2019-06-06 2019-06-05 4 SAGE Sage Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 10,000 10,000
2019-03-22 2019-03-21 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -1,967 122,400 -1.58 161.02 -316,726 19,708,848
2019-03-22 2019-03-21 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -2,919 124,367 -2.29 161.05 -470,105 20,029,305
2019-03-22 2019-03-21 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -2,993 127,286 -2.30 161.04 -481,993 20,498,137
2019-03-20 2019-03-20 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -13,047 130,279 -9.10 161.35 -2,105,133 21,020,517
2019-03-20 2019-03-20 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -13,096 143,326 -8.37 161.32 -2,112,647 23,121,350
2019-03-20 2019-03-20 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -16,182 156,422 -9.38 161.20 -2,608,538 25,215,226
2019-03-20 2019-03-20 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -14,321 172,604 -7.66 161.32 -2,310,264 27,844,477
2019-03-20 2019-03-18 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -875 186,925 -0.47 161.01 -140,884 30,096,794
2019-03-20 2019-03-18 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -800 187,800 -0.42 161.02 -128,816 30,239,556
2019-03-20 2019-03-18 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -1,200 188,600 -0.63 161.14 -193,368 30,391,004
2019-03-20 2019-03-18 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -900 189,800 -0.47 161.01 -144,909 30,559,698
2019-03-05 2019-03-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -700 190,700 -0.37 161.00 -112,700 30,702,700
2019-03-05 2019-03-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -700 190,700 -0.37 161.00 -112,700 30,702,700
2019-03-05 2019-03-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -700 190,700 -0.37 161.00 -112,700 30,702,700
2019-03-05 2019-03-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 192,100 -0.26 161.00 -80,500 30,928,100
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 30,600 193,300 18.81
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 30,600 193,300 18.81
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 30,600 435,477 7.56
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 30,600 404,877 8.18
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -122,400 119,295 -50.64
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 70,900 -0.70 161.00 -80,500 11,414,900
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 70,900 -0.70 161.00 -80,500 11,414,900
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 344,177 -0.15 161.00 -80,500 55,412,497
2019-02-27 2019-02-25 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 344,677 -0.14 161.00 -80,500 55,492,997
2019-02-20 2019-02-19 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -200 72,900 -0.27 162.00 -32,400 11,809,800
2019-02-20 2019-02-19 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -200 72,900 -0.27 162.00 -32,400 11,809,800
2019-02-20 2019-02-19 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -643 73,100 -0.87 161.37 -103,761 11,796,147
2019-02-20 2019-02-19 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -500 73,743 -0.67 161.62 -80,812 11,918,639
2019-02-20 2019-02-15 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -12,388 74,443 -14.27 161.02 -1,994,716 11,986,812
2019-02-20 2019-02-15 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -12,044 86,831 -12.18 161.02 -1,939,325 13,981,528
2019-02-20 2019-02-15 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -12,510 98,875 -11.23 161.02 -2,014,360 15,920,852
2019-02-20 2019-02-15 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -12,519 111,385 -10.10 161.02 -2,015,809 17,935,213
2019-02-20 2019-02-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 241,695 241,695
2019-02-20 2019-02-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -241,695 272,777 -46.98
2019-02-14 2018-07-26 5 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 123,904 123,904
2019-02-14 2018-07-26 5 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -123,904 0 -100.00
2019-02-14 2018-07-13 5 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift 121,035 123,904 4,218.72
2019-02-14 2018-07-13 5 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -121,035 514,472 -19.05
2018-06-22 2018-06-20 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 9,000 9,000
2018-06-08 2018-06-06 4 SAGE Sage Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 10,000 10,000
2018-03-09 2018-03-07 4 VYGR Voyager Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 110,000 110,000
2018-03-08 2018-03-06 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -58,139 632,712 -8.42 172.00 -9,999,908 108,826,464
2017-06-08 2017-06-07 4 SAGE Sage Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 14,000 14,000
2017-06-06 2017-06-02 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 11,250 11,250
2017-02-17 2017-01-31 4 SAGE Sage Therapeutics, Inc.
Common Stock
J - Other 2,174 690,851 0.32 3.15 6,848 2,176,181
2017-02-10 2017-02-08 4 VYGR Voyager Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 240,000 240,000 11.83 2,839,200 2,839,200
2016-06-24 2016-06-22 4 SAGE Sage Therapeutics, Inc.
Stock Options (Right to buy)
A - Award 13,922 13,922 28.35 394,689 394,689
2016-06-07 2016-06-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 11,250 11,250
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -847 4,763,954 -0.02
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -847 4,763,954 -0.02
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -847 4,763,954 -0.02
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -423 4,763,954 -0.01
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -423 678,569 -0.06
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -847 678,992 -0.12
2016-04-05 2016-02-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
G - Gift -847 678,992 -0.12
2016-02-02 2016-02-01 4 VYGR Voyager Therapeutics, Inc.
Stock Options (Right to Buy)
A - Award 200,000 200,000 11.09 2,218,000 2,218,000
2016-01-15 2016-01-14 4 VYGR Voyager Therapeutics, Inc.
Common Stock
P - Purchase 10,000 872,351 1.16 14.07 140,690 12,273,106
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
D - Sale to Issuer -624 0 -100.00
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
D - Sale to Issuer -374 0 -100.00
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -4,430 0 -100.00 92.78 -411,015
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -6,800 0 -100.00 74.77 -508,436
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option, Right to Buy
D - Sale to Issuer -10,000 0 -100.00 71.10 -711,000
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option, Right to Buy
D - Sale to Issuer -10,000 0 -100.00 69.14 -691,400
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -10,000 0 -100.00 57.76 -577,600
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -10,000 0 -100.00 44.58 -445,800
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -10,000 0 -100.00 57.05 -570,500
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
D - Sale to Issuer -20,000 0 -100.00 38.71 -774,200
2015-11-19 2015-11-18 4 SIAL SIGMA ALDRICH CORP
Common Stock
D - Sale to Issuer -478 0 -100.00 140.00 -66,920
2015-11-10 3 VYGR Voyager Therapeutics, Inc.
Common Stock
1,724,702
2015-11-10 3 VYGR Voyager Therapeutics, Inc.
Common Stock
1,724,702
2015-09-02 2015-09-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -9,518 683,650 -1.37 52.10 -495,888 35,618,165
2015-09-02 2015-09-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -10,482 693,168 -1.49 52.69 -552,297 36,523,022
2015-08-04 2015-08-03 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -6,020 703,650 -0.85 66.42 -399,848 46,736,433
2015-08-04 2015-08-03 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -9,158 709,670 -1.27 67.05 -614,044 47,583,374
2015-08-04 2015-08-03 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -4,822 718,828 -0.67 67.98 -327,800 48,865,927
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -803 723,650 -0.11 67.46 -54,170 48,817,429
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -9,702 724,453 -1.32 68.12 -660,900 49,349,738
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -1,859 734,155 -0.25 68.90 -128,085 50,583,280
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -1,600 736,014 -0.22 70.50 -112,800 51,888,987
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -5,336 737,614 -0.72 71.47 -381,364 52,717,273
2015-07-02 2015-07-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -700 742,950 -0.09 72.44 -50,708 53,819,298
2015-06-15 2015-05-29 4 SIAL SIGMA ALDRICH CORP
Common Stock
G - Gift -7,779 478 -94.21
2015-06-03 2015-06-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 11,250 11,250
2015-06-02 2015-06-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -8,705 743,650 -1.16 71.36 -621,153 53,063,815
2015-06-02 2015-06-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -3,291 752,355 -0.44 72.06 -237,162 54,217,560
2015-06-02 2015-06-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -4,604 755,646 -0.61 73.13 -336,710 55,263,641
2015-06-02 2015-06-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale X -3,400 760,250 -0.45 74.05 -251,774 56,297,425
2015-05-29 2015-05-28 4 SAGE Sage Therapeutics, Inc.
Stock Options (Right to buy)
A - Award 13,922 13,922 73.13 1,018,116 1,018,116
2015-05-05 2015-05-01 4 BFAM Sage Therapeutics, Inc.
Common Stock
S - Sale X -20,000 763,650 -2.55 53.31 -1,066,200 40,710,182
2015-04-02 2015-04-01 4 SAGE Sage Therapeutics, Inc.
Common Stock
S - Sale -20,000 783,650 -2.49 48.51 -970,200 38,014,862
2015-01-28 2015-01-26 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock
P - Purchase 1,000 1,000 95.00 95,000 95,000
2015-01-09 2015-01-02 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
M - Exercise -311 624 -33.26
2015-01-09 2015-01-02 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
M - Exercise -373 374 -49.93
2015-01-09 2015-01-02 4 SIAL SIGMA ALDRICH CORP
Common Stock
M - Exercise 311 8,257 3.91
2015-01-09 2015-01-02 4 SIAL SIGMA ALDRICH CORP
Common Stock
M - Exercise 373 7,946 4.93
2014-07-23 2014-07-23 4 SAGE Sage Therapeutics, Inc.
Common Stock
P - Purchase 10,000 803,650 1.26 18.00 180,000 14,465,700
2014-07-17 3 SAGE Sage Therapeutics, Inc.
Common Stock
1,587,300
2014-07-17 3 SAGE Sage Therapeutics, Inc.
Common Stock
1,587,300
2014-06-06 2014-06-05 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 15,000 15,000
2014-01-06 2014-01-02 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
M - Exercise -373 747 -33.30
2014-01-06 2014-01-02 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
A - Award 935 935
2014-01-06 2014-01-02 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
A - Award 4,430 4,430
2014-01-06 2014-01-02 4 SIAL SIGMA ALDRICH CORP
Common Stock
M - Exercise 373 7,573 5.18
2014-01-03 2014-01-02 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 3,388 3,388
2013-06-10 2013-06-06 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (Right to Buy)
A - Award 15,000 15,000
2013-01-04 2013-01-02 4 SIAL SIGMA ALDRICH CORP
Restricted Stock Unit
A - Award 1,120 1,120
2013-01-04 2013-01-02 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option Right to Buy
A - Award 6,800 6,800
2012-06-25 2012-06-21 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (Right to Buy)
A - Award 15,000 15,000
2012-05-04 2012-05-02 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option, Right to Buy
A - Award 10,000 10,000
2012-01-19 2012-01-03 4/A SIAL SIGMA ALDRICH CORP
Common Stock
A - Award 1,200 7,200 20.00
2012-01-05 2012-01-03 4 SIAL SIGMA ALDRICH CORP
Common Stock
A - Award 1,200 2,400 100.00
2011-06-13 2011-06-09 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Stock Option (right to buy)
A - Award 15,000 15,000
2011-05-06 2011-05-04 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option, Right to Buy
A - Award 10,000 10,000 69.14 691,400 691,400
2011-01-05 2011-01-03 4 SIAL SIGMA ALDRICH CORP
Common Stock, $1 Par Value
A - Award 1,200 6,000 25.00 67.30 80,760 403,800
2010-09-24 2010-09-22 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy)
A - Award 30,000 30,000
2010-01-11 2010-01-07 4 SIAL SIGMA ALDRICH CORP
Common Stock, $1 Par Value
A - Award 1,200 4,800 33.33 50.59 60,708 242,832
2009-05-07 2009-05-06 4 SIAL SIGMA ALDRICH CORP
NQ Stock Option, Right to Buy
A - Award 10,000 10,000 44.58 445,780 445,780
2009-01-06 2009-01-02 4 SIAL SIGMA ALDRICH CORP
Common Stock, Par Value $1
A - Award 1,200 1,200
2009-01-06 2009-01-02 4/A SIAL SIGMA ALDRICH CORP
Common Stock, $1 Par Value
A - Award 1,200 3,600 50.00
2006-11-15 3 SIAL SIGMA ALDRICH CORP
Common Stock, $1 Par Value
0
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)