Protagonist Therapeutics, Inc.
US ˙ NasdaqGM ˙ US74366E1029

Introduction

This page provides a comprehensive analysis of the known insider trading history of Dinesh V Ph D Patel. Insiders are officers, directors, or significant investors in a company. It is illegal for insiders to make trades in their companies based on specific, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4. Despite these restrictions, academic research suggests that insiders - in general - tend to outperform the market in their own companies.

Average Trade Profitability

The average trade profitability is the average return of all the open market purchases made by the insider in the last three years. To calculate this, we examine every open-market, unplanned purchase made by the insider, excluding all trades that were marked as part of a 10b5-1 trading plan. We then calculate the average performance of those trades over 3, 6, and 12 months, averaging each of those durations to generate a final performance metric for each trade. Finally, we average all of the performance metrics to calculate a performance metric for the insider. This list only includes insiders that have made at least three trades in the last two years.

If this insiders trade profitability is "N/A", then the insider either has not made any open-market purchases in the last three years, or the trades they’ve made are too recent to calculate a reliable performance metric.

Update Frequency: Daily

See the list of most profitable insider traders.

Companies with Reported Insider Positions

The SEC filings indicate Dinesh V Ph D Patel has reported holdings or trades in the following companies:

Security Title Latest Reported Holdings
US:PTGX / Protagonist Therapeutics, Inc. President and CEO, Director 520,603
How to Interpret the Charts

The following charts show the stock performance of securities subsequent to each open-market, non-planned trade made by Dinesh V Ph D Patel. Non-planned trade are trades that were not made as part of a 10b5-1 trading plan. The stock performance is charted as cumulative percent change in share price. For example, if an insider trade was made on January 1, 2019, the chart will show the daily percent change of the security to the present day. If the share price were to go from $10 to $15 during this time, the cumulative percent change in share price would be 50%. A change in price from $10 to $20 would be 100%, and a change in price of $10 to $5 would be -50%.

Ultimately, we are trying to determine how closely the insider’s trades correlate to excess returns (positive or negative) in the share price in order to see if the insider is timing their trades to profit from insider information. Consider the situation where an insider was doing this. In this situation, we would expect either (a) positive returns after purchases, or (b) negative returns after sales. In the case of (a), the PURCHASE chart would show a series of upwardly sloping curves, indicating positive returns after each purchase transaction. In the case of (b), the SALE chart would show a series of downward sloping curves, indicating negative returns after each sale transaction.

However, this alone is not enough to draw conclusions. If, for example, the share price of the company was in a non-cyclical climb over many years, then we would expect all the post-purchase plots to be upwardly sloping. Likewise, non-cyclical declines over many years would result in downward sloping post-trade plots. Neither of these charts would suggest insider trading activity.

The strongest indicator would be a situation where the share price was extremely cyclical, and there were both positive signals in the PURCHASE chart and negative plots on the SALE chart. This situation would be highly suggestive of an insider that was timing trades to their financial advantage.

Insider Purchases PTGX / Protagonist Therapeutics, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in PTGX / Protagonist Therapeutics, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
2019-12-03 PTGX PATEL DINESH V PH D 10,000 5.5500 10,000 5.5500 55,500 363 24.1600 186,100 335.32
2019-12-03 PTGX PATEL DINESH V PH D 20,000 5.6500 20,000 5.6500 113,000

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

PTGX / Protagonist Therapeutics, Inc. Insider Trades
Insider Sales PTGX / Protagonist Therapeutics, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in PTGX / Protagonist Therapeutics, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
2025-07-25 PTGX PATEL DINESH V PH D 10,415 54.7800 10,415 54.7800 570,534 13 50.9600 -39,785 -6.97
2025-07-23 PTGX PATEL DINESH V PH D 17,520 54.7900 17,520 54.7900 959,921
2025-07-22 PTGX PATEL DINESH V PH D 22,065 55.0500 22,065 55.0500 1,214,678
2025-07-21 PTGX PATEL DINESH V PH D 12,859 54.8600 12,859 54.8600 705,445
2025-02-19 PTGX PATEL DINESH V PH D 5,359 38.1800 5,359 38.1800 204,607
2024-11-26 PTGX PATEL DINESH V PH D 21,480 46.2500 21,480 46.2500 993,450
2024-11-25 PTGX PATEL DINESH V PH D 78,520 46.9600 78,520 46.9600 3,687,299
2021-12-21 PTGX PATEL DINESH V PH D 15,000 32.1447 15,000 32.1447 482,170
2019-08-06 PTGX PATEL DINESH V PH D 10,792 8.8524 10,792 8.8524 95,535
2019-03-01 PTGX PATEL DINESH V PH D 2,183 8.0300 2,183 8.0300 17,529
2019-02-06 PTGX PATEL DINESH V PH D 777 8.0981 777 8.0981 6,292
2019-02-06 PTGX PATEL DINESH V PH D 10,132 7.7100 10,132 7.7100 78,118

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

PTGX / Protagonist Therapeutics, Inc. Insider Trades
Insider Trading History

This table shows the complete list of insider trades made by Dinesh V Ph D Patel as disclosed to the Securities Exchange Commission (SEC).

File Date Tran Date Form Ticker Security Code 10b5-1 Shares Remaining Shares Percent
Change
Share
Price
Tran
Value
Remaining
Value
2025-07-28 2025-07-25 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -10,415 520,603 -1.96 54.78 -570,534 28,518,632
2025-07-23 2025-07-23 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -17,520 531,018 -3.19 54.79 -959,921 29,094,476
2025-07-23 2025-07-22 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -22,065 548,538 -3.87 55.05 -1,214,678 30,197,017
2025-07-23 2025-07-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -12,859 570,603 -2.20 54.86 -705,445 31,303,281
2025-07-23 2025-07-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 25,000 583,462 4.48
2025-07-18 2025-07-16 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -5,000 558,462 -0.89
2025-06-17 2025-06-16 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -685 562,905 -0.12
2025-06-17 2025-06-13 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -670 563,590 -0.12
2025-03-05 2025-03-05 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 24,000 564,260 4.44 4.21 101,040 2,375,535
2025-02-20 2025-02-19 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -5,359 540,260 -0.98 38.18 -204,607 20,627,127
2025-01-17 2025-01-15 4 PTGX Protagonist Therapeutics, Inc
Common Stock
F - Taxes -12,636 545,619 -2.26
2025-01-06 2025-01-02 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 149,800 558,255 36.67
2024-11-27 2024-11-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -21,480 408,455 -5.00 46.25 -993,450 18,891,044
2024-11-27 2024-11-25 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 1,727 429,935 0.40 21.58 37,269 9,277,997
2024-11-27 2024-11-25 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -7,000 428,208 -1.61
2024-11-27 2024-11-25 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -78,520 435,208 -15.28 46.96 -3,687,299 20,437,368
2024-11-21 2024-11-19 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -1,000 513,415 -0.19
2024-06-17 2024-06-13 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -1,000 514,415 -0.19
2024-06-11 2024-06-07 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -35,000 515,415 -6.36 35.19 -1,231,650 18,137,454
2024-04-02 2024-04-01 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -25,000 549,590 -4.35 28.31 -707,750 15,558,893
2024-03-01 2024-03-01 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -30,000 574,590 -4.96 31.62 -948,600 18,168,536
2024-02-28 2024-02-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
F - Taxes -10,915 604,590 -1.77 29.53 -322,320 17,853,543
2024-02-20 2024-02-15 4 PTGX Protagonist Therapeutics, Inc
Common Stock
F - Taxes -3,717 615,505 -0.60 28.23 -104,931 17,375,706
2024-01-04 2024-01-02 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 84,875 619,222 15.88
2023-12-15 2023-12-13 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -75,000 534,347 -12.31 20.08 -1,506,000 10,729,688
2023-10-19 2023-10-18 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 6,000 609,347 0.99 4.21 25,260 2,565,351
2023-06-02 2023-05-31 4 PTGX Protagonist Therapeutics, Inc
Common Stock
F - Taxes -12,165 602,946 -1.98 26.07 -317,142 15,718,802
2023-06-02 2023-05-31 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 30,000 615,111 5.13
2023-06-02 2023-02-22 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -10,000 583,448 -1.69
2023-01-18 2022-12-28 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -3,116 598,096 -0.52
2023-01-18 2022-05-04 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -3,000 581,048 -0.51
2022-08-24 2022-08-23 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 20,000 604,048 3.42 4.21 84,200 2,543,042
2022-05-04 2022-05-04 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -15,742 80,000 -16.44
2022-05-04 2022-05-04 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 15,742 584,048 2.77 4.21 66,274 2,458,842
2022-04-26 2022-04-26 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -30,000 95,742 -23.86
2022-04-26 2022-04-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 30,000 568,306 5.57 4.21 126,300 2,392,568
2022-04-14 2022-04-14 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -34,087 0 -100.00
2022-04-14 2022-04-14 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 34,087 537,847 6.77 1.89 64,424 1,016,531
2022-03-02 2022-02-28 4 PTGX Protagonist Therapeutics, Inc
Common Stock
F - Taxes -4,648 503,760 -0.91 24.28 -112,853 12,231,293
2022-02-17 2022-02-15 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 187,500 187,500
2022-02-17 2022-02-15 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 31,250 508,408 6.55
2021-12-23 2021-12-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -15,000 477,158 -3.05 32.14 -482,170 15,338,101
2021-09-21 2021-09-21 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -40,000 125,742 -24.13
2021-09-21 2021-09-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 40,000 492,158 8.85 4.21 168,400 2,071,985
2021-02-26 2021-02-26 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 225,000 225,000
2021-02-26 2021-02-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 25,000 451,144 5.87
2021-01-20 2021-01-19 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -13,000 165,742 -7.27
2021-01-20 2021-01-19 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -24,846 426,144 -5.51 24.60 -611,105 10,481,310
2021-01-20 2021-01-19 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 13,000 450,990 2.97 4.21 54,730 1,898,668
2020-05-01 2020-04-29 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -2,000 437,990 -0.45
2020-03-23 2020-03-20 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -10,000 34,087 -22.68
2020-03-23 2020-03-20 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 10,000 439,990 2.33 1.89 18,900 831,581
2020-03-13 2020-03-12 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -18,344 0 -100.00
2020-03-13 2020-03-12 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 18,344 429,990 4.46 1.16 21,279 498,788
2020-02-28 2020-02-28 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 235,000 235,000
2019-12-03 2019-12-03 4 PTGX Protagonist Therapeutics, Inc
Common Stock
P - Purchase 20,000 409,824 5.13 5.65 113,000 2,315,506
2019-12-03 2019-12-03 4 PTGX Protagonist Therapeutics, Inc
Common Stock
P - Purchase 10,000 389,824 2.63 5.55 55,500 2,163,523
2019-11-27 2019-11-26 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -4,000 18,343 -17.90
2019-11-27 2019-11-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 4,000 379,824 1.06 1.16 4,640 440,596
2019-08-08 2019-08-06 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -10,792 374,792 -2.80 8.85 -95,535 3,317,809
2019-03-04 2019-03-01 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -2,183 383,831 -0.57 8.03 -17,529 3,082,163
2019-03-04 2019-02-28 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 172,500 172,500
2019-03-04 2019-02-28 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 28,750 386,014 8.05
2019-02-08 2019-02-06 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -10,132 357,264 -2.76 7.71 -78,118 2,754,505
2019-02-08 2019-02-06 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale -777 367,396 -0.21 8.10 -6,292 2,975,210
2019-01-14 2019-01-11 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -22,344 22,343 -50.00
2019-01-14 2019-01-11 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 22,344 368,173 6.46 1.16 25,919 427,081
2018-08-17 2018-08-15 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 54,700 54,700
2018-08-17 2018-08-15 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 82,050 345,829 31.11
2018-07-13 2018-07-12 4 PTGX Protagonist Therapeutics, Inc
Common Stock
G - Gift -2,000 263,779 -0.75
2018-05-11 2018-05-10 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -13,516 44,687 -23.22
2018-05-11 2018-05-10 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 13,516 265,779 5.36 1.16 15,679 308,304
2018-04-03 2018-04-02 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -20,000 58,203 -25.57
2018-04-03 2018-04-02 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 20,000 252,263 8.61 1.16 23,200 292,625
2018-03-28 2018-03-26 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -11,298 0 -100.00
2018-03-28 2018-03-26 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 11,298 232,263 5.11 0.87 9,829 202,069
2018-03-02 2018-02-28 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 150,000 150,000
2018-03-02 2018-02-28 4 PTGX Protagonist Therapeutics, Inc
Common Stock
A - Award 25,000 219,259 12.87
2017-12-21 2017-12-21 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -8,210 44,087 -15.70
2017-12-21 2017-12-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -8,210 190,437 -4.13 19.56 -160,570 3,724,529
2017-12-21 2017-12-21 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 8,210 198,647 4.31 1.89 15,517 375,443
2017-12-20 2017-12-20 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -1,790 52,297 -3.31
2017-12-20 2017-12-20 4 PTGX Protagonist Therapeutics, Inc
Common Stock
S - Sale X -1,790 190,437 -0.93 19.55 -34,987 3,722,282
2017-12-20 2017-12-20 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 1,790 192,227 0.94 1.89 3,383 363,309
2017-05-10 2017-05-09 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -19,099 78,203 -19.63
2017-05-10 2017-05-09 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 19,099 190,437 11.15 1.16 22,155 220,907
2017-04-07 2017-04-06 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -20,000 97,302 -17.05
2017-04-07 2017-04-06 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 20,000 171,338 13.22 1.16 23,200 198,752
2017-03-13 2017-03-10 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -16,362 11,297 -59.16
2017-03-13 2017-03-10 4 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 16,362 151,338 12.12 0.87 14,235 131,664
2017-02-03 2016-12-22 5 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
M - Exercise -3,000 27,659 -9.79
2017-02-03 2016-12-22 5 PTGX Protagonist Therapeutics, Inc
Common Stock
M - Exercise 3,000 134,976 2.27 0.87 2,610 117,429
2016-10-13 2016-10-11 4 PTGX Protagonist Therapeutics, Inc
Stock Option (right to buy)
A - Award 320,000 320,000
2016-08-10 3 PTGX Protagonist Therapeutics, Inc
Common Stock
263,952
2016-08-10 3 PTGX Protagonist Therapeutics, Inc
Common Stock
263,952
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)