Caribou Biosciences, Inc.
US ˙ NasdaqGS ˙ US1420381089

Introduction

This page provides a comprehensive analysis of the known insider trading history of Andrew Guggenhime. Insiders are officers, directors, or significant investors in a company. It is illegal for insiders to make trades in their companies based on specific, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4. Despite these restrictions, academic research suggests that insiders - in general - tend to outperform the market in their own companies.

Average Trade Profitability

The average trade profitability is the average return of all the open market purchases made by the insider in the last three years. To calculate this, we examine every open-market, unplanned purchase made by the insider, excluding all trades that were marked as part of a 10b5-1 trading plan. We then calculate the average performance of those trades over 3, 6, and 12 months, averaging each of those durations to generate a final performance metric for each trade. Finally, we average all of the performance metrics to calculate a performance metric for the insider. This list only includes insiders that have made at least three trades in the last two years.

If this insiders trade profitability is "N/A", then the insider either has not made any open-market purchases in the last three years, or the trades they’ve made are too recent to calculate a reliable performance metric.

Update Frequency: Daily

See the list of most profitable insider traders.

Companies with Reported Insider Positions

The SEC filings indicate Andrew Guggenhime has reported holdings or trades in the following companies:

Security Title Latest Reported Holdings
US:PCVX / Vaxcyte, Inc. PRESIDENT AND CFO 127,199
US:CRBU / Caribou Biosciences, Inc. Director 27,500
US:MTCR / Metacrine Inc Director 16,500
US:DERM / Journey Medical Corporation CFO 0
How to Interpret the Charts

The following charts show the stock performance of securities subsequent to each open-market, non-planned trade made by Andrew Guggenhime. Non-planned trade are trades that were not made as part of a 10b5-1 trading plan. The stock performance is charted as cumulative percent change in share price. For example, if an insider trade was made on January 1, 2019, the chart will show the daily percent change of the security to the present day. If the share price were to go from $10 to $15 during this time, the cumulative percent change in share price would be 50%. A change in price from $10 to $20 would be 100%, and a change in price of $10 to $5 would be -50%.

Ultimately, we are trying to determine how closely the insider’s trades correlate to excess returns (positive or negative) in the share price in order to see if the insider is timing their trades to profit from insider information. Consider the situation where an insider was doing this. In this situation, we would expect either (a) positive returns after purchases, or (b) negative returns after sales. In the case of (a), the PURCHASE chart would show a series of upwardly sloping curves, indicating positive returns after each purchase transaction. In the case of (b), the SALE chart would show a series of downward sloping curves, indicating negative returns after each sale transaction.

However, this alone is not enough to draw conclusions. If, for example, the share price of the company was in a non-cyclical climb over many years, then we would expect all the post-purchase plots to be upwardly sloping. Likewise, non-cyclical declines over many years would result in downward sloping post-trade plots. Neither of these charts would suggest insider trading activity.

The strongest indicator would be a situation where the share price was extremely cyclical, and there were both positive signals in the PURCHASE chart and negative plots on the SALE chart. This situation would be highly suggestive of an insider that was timing trades to their financial advantage.

Insider Purchases CRBU / Caribou Biosciences, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in CRBU / Caribou Biosciences, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

CRBU / Caribou Biosciences, Inc. Insider Trades
Insider Sales CRBU / Caribou Biosciences, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in CRBU / Caribou Biosciences, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

CRBU / Caribou Biosciences, Inc. Insider Trades
Insider Purchases DERM / Journey Medical Corporation - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in CRBU / Caribou Biosciences, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

DERM / Journey Medical Corporation Insider Trades
Insider Sales DERM / Journey Medical Corporation - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in CRBU / Caribou Biosciences, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

DERM / Journey Medical Corporation Insider Trades
Insider Purchases PCVX / Vaxcyte, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in CRBU / Caribou Biosciences, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

PCVX / Vaxcyte, Inc. Insider Trades
Insider Sales PCVX / Vaxcyte, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in CRBU / Caribou Biosciences, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

PCVX / Vaxcyte, Inc. Insider Trades
Insider Trading History

This table shows the complete list of insider trades made by Andrew Guggenhime as disclosed to the Securities Exchange Commission (SEC).

File Date Tran Date Form Ticker Security Code 10b5-1 Shares Remaining Shares Percent
Change
Share
Price
Tran
Value
Remaining
Value
2025-09-04 2025-09-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -1,429 127,199 -1.11 31.56 -45,099 4,014,400
2025-09-04 2025-09-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -2,381 128,628 -1.82 31.56 -75,144 4,059,500
2025-09-04 2025-09-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -1,270 131,009 -0.96 31.56 -40,081 4,134,644
2025-04-09 2025-04-07 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 4,777 131,950 3.76 20.93 99,983 2,761,714
2025-03-03 2025-03-03 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -3,809 127,173 -2.91 72.10 -274,629 9,169,173
2025-03-03 2025-02-28 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -1,270 130,982 -0.96 73.02 -92,735 9,564,306
2025-03-03 2025-02-27 4 PCVX Vaxcyte, Inc.
Common Stock
A - Award 22,761 132,252 20.79
2025-02-19 2025-02-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,818 109,491 -1.63 84.58 -153,766 9,260,749
2025-02-19 2025-02-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -6,182 111,309 -5.26 83.64 -517,056 9,309,773
2025-02-19 2025-02-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 117,491 7.31 5.35 42,800 628,577
2025-01-22 2025-01-21 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -683 109,491 -0.62 87.70 -59,899 9,602,361
2025-01-22 2025-01-21 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,999 110,174 -1.78 87.25 -174,407 9,612,351
2025-01-22 2025-01-21 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -5,318 112,173 -4.53 86.08 -457,795 9,656,301
2025-01-22 2025-01-21 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 117,491 7.31 5.35 42,800 628,577
2024-12-19 2024-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -280 109,491 -0.26 90.24 -25,267 9,880,577
2024-12-19 2024-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,157 109,771 -2.80 89.31 -281,958 9,803,868
2024-12-19 2024-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,373 112,928 -2.90 88.70 -299,188 10,016,827
2024-12-19 2024-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,190 116,301 -1.01 87.26 -103,835 10,147,960
2024-12-19 2024-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 117,491 7.31 5.35 42,800 628,577
2024-11-19 2024-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -132 109,491 -0.12 87.05 -11,491 9,531,192
2024-11-19 2024-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,757 109,623 -1.58 86.49 -151,956 9,480,855
2024-11-19 2024-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -6,111 111,380 -5.20 85.60 -523,071 9,533,571
2024-11-19 2024-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 117,491 7.31 5.35 42,800 628,577
2024-10-28 2024-10-25 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 19,108 109,491 21.14 20.93 399,930 2,291,647
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -5,886 90,383 -6.11 116.19 -683,900 10,501,691
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -36,114 96,269 -27.28 115.26 -4,162,608 11,096,254
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 14,000 132,383 11.83 5.35 74,900 708,249
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 12,000 118,383 11.28 5.35 64,200 633,349
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 106,383 8.13 5.35 42,800 569,149
2024-10-22 2024-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 106,383 8.13 5.35 42,800 569,149
2024-09-19 2024-09-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -829 90,383 -0.91 117.53 -97,433 10,622,813
2024-09-19 2024-09-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,686 91,212 -1.81 116.29 -196,065 10,607,043
2024-09-19 2024-09-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -5,485 92,898 -5.58 115.60 -634,052 10,738,777
2024-09-19 2024-09-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 98,383 8.85 5.35 42,800 526,349
2024-09-05 2024-09-03 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -6,337 90,383 -6.55 110.15 -698,021 9,955,687
2024-08-20 2024-08-19 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,006 96,720 -3.01 79.14 -237,880 7,653,937
2024-08-20 2024-08-19 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -4,994 99,726 -4.77 78.25 -390,771 7,803,360
2024-08-20 2024-08-19 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 104,720 8.27 5.35 42,800 560,252
2024-07-22 2024-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -926 96,720 -0.95 83.14 -76,985 8,041,011
2024-07-22 2024-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,479 97,646 -1.49 82.32 -121,747 8,037,926
2024-07-22 2024-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,500 99,125 -2.46 81.06 -202,638 8,034,577
2024-07-22 2024-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,095 101,625 -2.96 80.12 -247,956 8,141,687
2024-07-22 2024-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 104,720 8.27 5.35 42,800 560,252
2024-06-20 2024-06-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -348 96,720 -0.36 72.56 -25,249 7,017,616
2024-06-20 2024-06-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,652 97,068 -7.31 71.89 -550,125 6,978,510
2024-06-20 2024-06-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 104,720 8.27 5.35 42,800 560,252
2024-05-22 2024-05-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -4,456 95,679 -4.45 75.46 -336,250 7,219,937
2024-05-22 2024-05-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,544 100,135 -3.42 74.40 -263,659 7,449,643
2024-05-22 2024-05-20 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 103,679 8.36 5.35 42,800 554,683
2024-04-22 2024-04-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -376 95,679 -0.39 61.90 -23,275 5,922,721
2024-04-22 2024-04-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,624 96,055 -7.35 61.24 -466,924 5,882,792
2024-04-22 2024-04-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 103,679 8.36 5.35 42,800 554,683
2024-03-20 2024-03-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -236 95,679 -0.25 69.64 -16,436 6,663,277
2024-03-20 2024-03-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,764 95,915 -7.49 69.00 -535,708 6,618,039
2024-03-20 2024-03-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 103,679 8.36 5.35 42,800 554,683
2024-03-04 2024-03-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -3,795 95,679 -3.82 71.55 -271,532 6,845,832
2024-03-04 2024-02-29 4 PCVX Vaxcyte, Inc.
Common Stock
A - Award 20,000 99,474 25.17
2024-02-22 2024-02-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -340 79,474 -0.43 75.80 -25,772 6,024,129
2024-02-22 2024-02-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,751 79,814 -3.33 75.17 -206,801 5,999,858
2024-02-22 2024-02-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -4,909 82,565 -5.61 74.08 -363,659 6,116,415
2024-02-22 2024-02-20 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 87,474 10.07 5.35 42,800 467,986
2024-01-19 2024-01-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -23 79,474 -0.03 63.35 -1,457 5,034,678
2024-01-19 2024-01-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -463 79,497 -0.58 61.88 -28,651 4,919,354
2024-01-19 2024-01-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,127 79,960 -3.76 61.19 -191,344 4,892,832
2024-01-19 2024-01-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -4,387 83,087 -5.02 60.28 -264,426 5,008,069
2024-01-19 2024-01-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 87,474 10.07 5.35 42,800 467,986
2023-12-20 2023-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -117 79,474 -0.15 60.79 -7,112 4,831,224
2023-12-20 2023-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,883 79,591 -9.01 60.17 -474,304 4,788,831
2023-12-20 2023-12-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 87,474 10.07 5.35 42,800 467,986
2023-12-18 2023-12-14 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -14,000 79,474 -14.98 60.22 -843,080 4,785,924
2023-12-18 2023-12-14 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 14,000 93,474 17.62 5.35 74,900 500,086
2023-11-22 2023-11-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -124 79,474 -0.16 51.95 -6,442 4,128,674
2023-11-22 2023-11-20 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,876 79,598 -9.00 51.12 -402,621 4,069,050
2023-11-22 2023-11-20 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 87,474 10.07 5.35 42,800 467,986
2023-10-20 2023-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -503 79,474 -0.63 46.32 -23,300 3,681,474
2023-10-20 2023-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -7,497 79,977 -8.57 45.88 -344,000 3,669,745
2023-10-20 2023-10-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 8,000 87,474 10.07 5.35 42,800 467,986
2023-09-06 2023-09-05 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -3,568 79,474 -4.30 51.00 -181,968 4,053,174
2023-03-03 2023-03-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -1,727 82,002 -2.06 41.49 -71,653 3,402,263
2023-03-03 2023-03-01 4 PCVX Vaxcyte, Inc.
Common Stock
A - Award 22,500 83,729 36.75
2023-01-04 2022-12-30 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 23,691 61,229 63.11 5.35 126,747 327,575
2022-09-21 2022-09-19 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -477 37,538 -1.25 26.52 -12,650 995,508
2022-09-21 2022-09-19 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,623 38,015 -6.45 26.02 -68,248 989,112
2022-09-21 2022-09-19 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 40,638 8.26 5.35 16,585 217,413
2022-09-07 2022-09-02 4 PCVX Vaxcyte, Inc.
Common Stock
F - Taxes -4,649 37,538 -11.02 26.38 -122,641 990,252
2022-08-29 2022-08-29 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -17,653 42,187 -29.50 28.00 -494,284 1,181,236
2022-08-29 2022-08-29 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 17,653 59,840 41.84 5.35 94,444 320,144
2022-08-29 2022-08-26 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -1,295 42,187 -2.98 28.00 -36,260 1,181,236
2022-08-29 2022-08-26 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 1,295 43,482 3.07 5.35 6,928 232,629
2022-08-29 2022-08-25 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -17,052 42,187 -28.79 28.00 -477,456 1,181,236
2022-08-29 2022-08-25 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 17,052 59,239 40.42 5.35 91,228 316,929
2022-08-22 2022-08-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -549 42,187 -1.28 25.89 -14,214 1,092,221
2022-08-22 2022-08-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,551 42,736 -5.63 25.13 -64,107 1,073,956
2022-08-22 2022-08-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 45,287 7.35 5.35 16,585 242,285
2022-07-20 2022-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -9 42,187 -0.02 25.00 -225 1,054,675
2022-07-20 2022-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,091 42,196 -6.83 24.53 -75,822 1,035,068
2022-07-20 2022-07-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 45,287 7.35 5.35 16,585 242,285
2022-07-12 2022-07-08 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,100 42,187 -6.85 24.00 -74,400 1,012,488
2022-07-12 2022-07-08 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 45,287 7.35 5.35 16,585 242,285
2022-05-20 2022-05-18 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -3,100 502,918 -0.61
2022-05-20 2022-05-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -580 42,187 -1.36 25.22 -14,628 1,063,956
2022-05-20 2022-05-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,520 42,767 -5.56 24.26 -61,135 1,037,527
2022-05-20 2022-05-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 45,287 7.35 5.35 16,585 242,285
2022-04-20 2022-04-18 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -3,100 506,018 -0.61
2022-04-20 2022-04-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,100 40,625 -7.09 24.05 -74,542 976,865
2022-04-20 2022-04-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 43,725 7.63 5.35 16,585 233,929
2022-03-22 2022-03-18 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -3,100 509,118 -0.61
2022-03-22 2022-03-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,100 40,625 -7.09 26.13 -80,993 1,061,397
2022-03-22 2022-03-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 43,725 7.63 5.35 16,585 233,929
2022-03-04 2022-03-02 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
A - Award 225,000 225,000
2022-03-04 2022-03-02 4 PCVX Vaxcyte, Inc.
Common Stock
A - Award 37,500 40,625 1,200.00
2022-03-03 2022-03-01 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -6,200 512,218 -1.20
2022-03-03 2022-03-01 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -6,200 3,125 -66.49 24.00 -148,800 75,000
2022-03-03 2022-03-01 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 6,200 9,325 198.40 5.35 33,170 49,889
2021-12-28 2021-12-23 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -3,100 518,418 -0.59
2021-12-28 2021-12-23 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -3,100 3,125 -49.80 24.00 -74,400 75,000
2021-12-28 2021-12-23 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 6,225 99.20 5.35 16,585 33,304
2021-12-21 2021-12-20 4 CRBU Caribou Biosciences, Inc.
Option to purchase Common Stock
A - Award 27,500 27,500
2021-11-22 2021-11-18 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
M - Exercise -3,100 521,518 -0.59
2021-11-22 2021-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -115 3,125 -3.55 25.20 -2,898 78,750
2021-11-22 2021-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
S - Sale X -2,985 3,240 -47.95 24.50 -73,132 79,380
2021-11-22 2021-11-18 4 PCVX Vaxcyte, Inc.
Common Stock
M - Exercise 3,100 6,225 99.20 5.35 16,585 33,304
2021-05-25 2021-05-24 4 MTCR Metacrine, Inc.
Stock Option (right to buy)
A - Award 16,500 16,500
2021-04-06 2021-04-01 4 PCVX Vaxcyte, Inc.
Stock Option (right to buy)
A - Award 145,000 145,000
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Restricted Stock Unit
D - Sale to Issuer -15,000 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Restricted Stock Unit
D - Sale to Issuer -25,000 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Restricted Stock Unit
D - Sale to Issuer -5,700 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Restricted Stock Unit
D - Sale to Issuer -3,562 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
D - Sale to Issuer -65,000 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
D - Sale to Issuer -57,000 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Stock Options (Right to buy)
D - Sale to Issuer -71,250 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
D - Sale to Issuer -71,250 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Stock Options (Right to buy)
D - Sale to Issuer -67,240 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Stock Options (Right to buy)
D - Sale to Issuer -73,287 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Stock Options (Right to buy)
D - Sale to Issuer -121 0 -100.00
2020-02-24 2020-02-20 4 DERM Dermira, Inc.
Common Stock
D - Sale to Issuer -41,951 0 -100.00 18.75 -786,581
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -3,562 0 -100.00
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -2,850 5,700 -33.33
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -3,563 3,562 -50.01
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -1,232 40,927 -2.92 7.91 -9,745 323,733
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -1,233 42,159 -2.84 7.91 -9,753 333,478
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -986 43,392 -2.22 7.91 -7,799 343,231
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 3,562 44,378 8.73
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 3,563 40,816 9.56
2019-08-19 2019-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 2,850 37,253 8.28
2019-05-21 2019-05-17 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -25,000 25,000 -50.00
2019-05-21 2019-05-17 4 DERM Dermira, Inc.
Common Stock
F - Taxes -8,645 34,403 -20.08 10.50 -90,772 361,232
2019-05-21 2019-05-17 4 DERM Dermira, Inc.
Common Stock
M - Exercise 25,000 43,048 138.52
2019-02-14 2019-02-12 4 DERM Dermira, Inc.
Restricted Stock Unit
A - Award 15,000 15,000
2019-02-14 2019-02-12 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
A - Award 65,000 65,000
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -3,563 3,562 -50.01
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -3,562 7,125 -33.33
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -950 8,550 -10.00
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
A - Award 50,000 50,000
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -1,233 16,496 -6.95 9.58 -11,812 158,032
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -1,232 17,729 -6.50 9.58 -11,803 169,844
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -329 18,961 -1.71 9.58 -3,152 181,646
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 3,563 19,290 22.66
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 3,562 15,727 29.28
2018-08-17 2018-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 950 12,165 8.47
2018-02-16 2018-02-15 4 DERM Dermira, Inc.
Restricted Stock Unit
A - Award 9,500 9,500
2018-02-16 2018-02-15 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
A - Award 57,000 57,000 28.25 1,610,250 1,610,250
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -3,562 7,125 -33.33
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -1,188 10,687 -10.00
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -447 10,073 -4.25 23.58 -10,540 237,521
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -1,339 10,520 -11.29 23.58 -31,574 248,062
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 1,188 11,859 11.13
2017-08-17 2017-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 3,562 10,671 50.11
2017-02-22 2017-02-17 4 DERM Dermira, Inc.
Restricted Stock Unit
A - Award 11,875 11,875
2017-02-22 2017-02-17 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
A - Award 71,250 71,250 33.84 2,411,100 2,411,100
2016-11-10 2016-11-09 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -4,100 120,513 -3.29
2016-11-10 2016-11-09 4 DERM Dermira, Inc.
Common Stock
S - Sale X -4,100 5,116 -44.49 35.02 -143,582 179,162
2016-11-10 2016-11-09 4 DERM Dermira, Inc.
Common Stock
M - Exercise 4,100 9,216 80.14 5.51 22,591 50,780
2016-10-13 2016-10-11 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -10,900 124,613 -8.04
2016-10-13 2016-10-11 4 DERM Dermira, Inc.
Common Stock
S - Sale X -1,605 5,116 -23.88 35.13 -56,384 179,725
2016-10-13 2016-10-11 4 DERM Dermira, Inc.
Common Stock
S - Sale X -9,295 6,721 -58.04 34.20 -317,889 229,858
2016-10-13 2016-10-11 4 DERM Dermira, Inc.
Common Stock
M - Exercise 10,900 16,016 213.06 5.51 60,059 88,248
2016-09-20 2016-09-19 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -15,000 135,513 -9.97
2016-09-20 2016-09-19 4 DERM Dermira, Inc.
Common Stock
S - Sale X -15,000 5,116 -74.57 35.01 -525,150 179,111
2016-09-20 2016-09-19 4 DERM Dermira, Inc.
Common Stock
M - Exercise 15,000 20,116 293.20 5.51 82,650 110,839
2016-09-14 2016-09-12 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -10,000 150,513 -6.23
2016-09-14 2016-09-12 4 DERM Dermira, Inc.
Common Stock
S - Sale X -10,000 5,116 -66.16 32.53 -325,300 166,423
2016-09-14 2016-09-12 4 DERM Dermira, Inc.
Common Stock
M - Exercise 10,000 15,116 195.47 5.51 55,100 83,289
2016-08-16 2016-08-15 4 DERM Dermira, Inc.
Restricted Stock Unit
M - Exercise -1,188 10,687 -10.00
2016-08-16 2016-08-15 4 DERM Dermira, Inc.
Common Stock
F - Taxes -447 5,116 -8.04 31.59 -14,121 161,614
2016-08-16 2016-08-15 4 DERM Dermira, Inc.
Common Stock
M - Exercise 1,188 5,563 27.15
2016-08-12 2016-08-11 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -10,000 160,513 -5.86
2016-08-12 2016-08-11 4 DERM Dermira, Inc.
Common Stock
S - Sale X -10,000 4,375 -69.57 31.02 -310,174 135,701
2016-08-12 2016-08-11 4 DERM Dermira, Inc.
Common Stock
M - Exercise 10,000 14,375 228.57 5.51 55,100 79,206
2016-07-12 2016-07-11 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
M - Exercise -10,000 170,513 -5.54
2016-07-12 2016-07-11 4 DERM Dermira, Inc.
Common Stock
S - Sale X -2,639 4,375 -37.62 29.80 -78,642 130,375
2016-07-12 2016-07-11 4 DERM Dermira, Inc.
Common Stock
S - Sale X -7,361 7,014 -51.21 30.28 -222,891 212,384
2016-07-12 2016-07-11 4 DERM Dermira, Inc.
Common Stock
M - Exercise 10,000 14,375 228.57 5.51 55,100 79,206
2016-02-09 2016-02-05 4 DERM Dermira, Inc.
Restricted Stock Unit
A - Award 11,875 11,875
2016-02-09 2016-02-05 4 DERM Dermira, Inc.
Employee Stock Options (Right to buy)
A - Award 71,250 71,250
2014-10-02 2014-10-02 4 DERM Dermira, Inc.
Employee Stock Option (right to buy)
A - Award 67,240 67,240
2014-10-02 2014-10-02 4 DERM Dermira, Inc.
Employee Stock Option (right to buy)
A - Award 73,287 73,287
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)