Evelo Biosciences, Inc.
US ˙ OTCPK ˙ US2997342025

Introduction

This page provides a comprehensive analysis of the known insider trading history of David R Epstein. Insiders are officers, directors, or significant investors in a company. It is illegal for insiders to make trades in their companies based on specific, non-public information. This does not mean it is illegal for them to make any trades in their own companies. However, they must report all trades to the SEC via a Form 4. Despite these restrictions, academic research suggests that insiders - in general - tend to outperform the market in their own companies.

Average Trade Profitability

The average trade profitability is the average return of all the open market purchases made by the insider in the last three years. To calculate this, we examine every open-market, unplanned purchase made by the insider, excluding all trades that were marked as part of a 10b5-1 trading plan. We then calculate the average performance of those trades over 3, 6, and 12 months, averaging each of those durations to generate a final performance metric for each trade. Finally, we average all of the performance metrics to calculate a performance metric for the insider. This list only includes insiders that have made at least three trades in the last two years.

If this insiders trade profitability is "N/A", then the insider either has not made any open-market purchases in the last three years, or the trades they’ve made are too recent to calculate a reliable performance metric.

Update Frequency: Daily

See the list of most profitable insider traders.

Companies with Reported Insider Positions

The SEC filings indicate David R Epstein has reported holdings or trades in the following companies:

Security Title Latest Reported Holdings
Director 27,041
US:SGEN / Seagen Inc CEO, Director 0
US:EVLO / Evelo Biosciences, Inc. Director 93,932
US:SNTI / Senti Biosciences, Inc. Director 123,252
US:AXLA / Axcella Health Inc. Director 209,756
US:RUBY / Rubius Therapeutics, Inc. Director 499,762
US:US6710051060 / OPY Acquisition Corp. I Director 0
US:IFF / International Flavors & Fragrances Inc. Director 6,397
How to Interpret the Charts

The following charts show the stock performance of securities subsequent to each open-market, non-planned trade made by David R Epstein. Non-planned trade are trades that were not made as part of a 10b5-1 trading plan. The stock performance is charted as cumulative percent change in share price. For example, if an insider trade was made on January 1, 2019, the chart will show the daily percent change of the security to the present day. If the share price were to go from $10 to $15 during this time, the cumulative percent change in share price would be 50%. A change in price from $10 to $20 would be 100%, and a change in price of $10 to $5 would be -50%.

Ultimately, we are trying to determine how closely the insider’s trades correlate to excess returns (positive or negative) in the share price in order to see if the insider is timing their trades to profit from insider information. Consider the situation where an insider was doing this. In this situation, we would expect either (a) positive returns after purchases, or (b) negative returns after sales. In the case of (a), the PURCHASE chart would show a series of upwardly sloping curves, indicating positive returns after each purchase transaction. In the case of (b), the SALE chart would show a series of downward sloping curves, indicating negative returns after each sale transaction.

However, this alone is not enough to draw conclusions. If, for example, the share price of the company was in a non-cyclical climb over many years, then we would expect all the post-purchase plots to be upwardly sloping. Likewise, non-cyclical declines over many years would result in downward sloping post-trade plots. Neither of these charts would suggest insider trading activity.

The strongest indicator would be a situation where the share price was extremely cyclical, and there were both positive signals in the PURCHASE chart and negative plots on the SALE chart. This situation would be highly suggestive of an insider that was timing trades to their financial advantage.

Insider Purchases EVLO / Evelo Biosciences, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in EVLO / Evelo Biosciences, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
2022-05-27 EVLO Epstein David R 17,123 1.4600 856 29.2000 25,000 73 60.2 26,532 106.13
2020-12-11 EVLO Epstein David R 200 6.4000 10 128.0000 1,280
2020-12-11 EVLO Epstein David R 30 6.4500 2 129.0000 194
2020-12-11 EVLO Epstein David R 4,970 6.4900 248 129.8000 32,255
2020-12-11 EVLO Epstein David R 800 7.1600 40 143.2000 5,728
2020-12-11 EVLO Epstein David R 1,000 6.9100 50 138.2000 6,910
2020-12-11 EVLO Epstein David R 500 6.9800 25 139.6000 3,490
2020-12-11 EVLO Epstein David R 200 7.0200 10 140.4000 1,404
2020-08-31 EVLO Epstein David R 2,752 4.4600 138 89.2000 12,274
2020-08-31 EVLO Epstein David R 1,000 4.4700 50 89.4000 4,470
2020-08-31 EVLO Epstein David R 1,000 4.4800 50 89.6000 4,480
2020-08-31 EVLO Epstein David R 1,000 4.5800 50 91.6000 4,580
2020-08-28 EVLO Epstein David R 1,000 4.3400 50 86.8000 4,340
2020-08-28 EVLO Epstein David R 3,248 4.4000 162 88.0000 14,291

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

EVLO / Evelo Biosciences, Inc. Insider Trades
Insider Sales EVLO / Evelo Biosciences, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in EVLO / Evelo Biosciences, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

EVLO / Evelo Biosciences, Inc. Insider Trades
Insider Purchases SNTI / Senti Biosciences, Inc. - Short Term Profit Analysis

In this section, we analyze the profitability of every unplanned, open-market insider purchase made in EVLO / Evelo Biosciences, Inc.. This analysis helps to understand if the insider consistently generates abnormal returns, and is worth following. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market purchases that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Max
Price at
Max
Max
Profit ($)
Max Return (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

SNTI / Senti Biosciences, Inc. Insider Trades
Insider Sales SNTI / Senti Biosciences, Inc. - Short Term Loss Analysis

In this section, we analyze the short-term loss avoidance of every unplanned, open-market insider sale made in EVLO / Evelo Biosciences, Inc.. A consistent pattern of loss avoidance may suggest that future sale transactions may predict declines in price. This analysis is for one-year following each trade, and the results are theoretical.

The following table shows the most recent open market sales that were not part of an automatic trading plan.

Trade Date Ticker Insider Reported
Shares
Reported
Price
Adjusted
Shares
Adjusted
Price
Cost Basis Days to
Min
Price at
Min
Max Loss
Avoided ($)
Max Loss
Avoided (%)
There are no known unplanned open-market trades for this insider and security combination

Adjusted Price is the split-adjusted price. Adjusted Shares is the split-adjusted shares.

SNTI / Senti Biosciences, Inc. Insider Trades
Insider Trading History

This table shows the complete list of insider trades made by David R Epstein as disclosed to the Securities Exchange Commission (SEC).

File Date Tran Date Form Ticker Security Code 10b5-1 Shares Remaining Shares Percent
Change
Share
Price
Tran
Value
Remaining
Value
2025-09-04 2025-09-02 4 TEM Tempus AI, Inc.
Class A Comnmon Stock
S - Sale X -250 27,041 -0.92 73.64 -18,410 1,991,299
2025-08-05 2025-08-01 4 TEM Tempus AI, Inc.
Class A Comnmon Stock
S - Sale X -370 27,291 -1.34 55.16 -20,409 1,505,372
2025-06-04 2025-06-02 4 TEM Tempus AI, Inc.
Class A Comnmon Stock
S - Sale X -250 27,661 -0.90 55.20 -13,800 1,526,887
2025-05-22 2025-05-20 4 TEM Tempus AI, Inc.
Class A Comnmon Stock
A - Award 1,997 27,911 7.71
2025-05-05 2025-05-01 4 TEM Tempus AI, Inc.
Class A Common Stock
S - Sale X -370 25,914 -1.41 53.50 -19,795 1,386,399
2025-03-19 2025-03-17 4 TEM Tempus AI, Inc.
Class A Common Stock
S - Sale X -990 26,284 -3.63 46.83 -46,362 1,230,880
2025-03-05 2025-03-03 4 TEM Tempus AI, Inc.
Class A Common Stock
S - Sale X -250 27,274 -0.91 57.52 -14,380 1,568,800
2025-02-05 2025-02-03 4 TEM Tempus AI, Inc.
Class A Common Stock
S - Sale X -370 27,524 -1.33 53.31 -19,725 1,467,304
2024-12-13 2024-12-11 4 TEM Tempus AI, Inc.
Class A Common Stock
S - Sale X -620 27,894 -2.17 41.81 -25,922 1,166,248
2024-06-17 2024-06-13 4 TEM Tempus AI, Inc.
Class A Common Stock
A - Award 28,514 28,514
2023-12-15 2023-12-14 4 SGEN Seagen Inc.
Common Stock
D - Sale to Issuer -16,407 0 -100.00 229.00 -3,757,203
2023-11-13 2023-11-10 4 SGEN Seagen Inc.
Common Stock
S - Sale X -10,620 136,598 -7.21 213.01 -2,262,166 29,096,740
2023-08-17 2023-08-15 4 SGEN Seagen Inc.
Common Stock
A - Award 39,650 147,218 36.86
2022-11-14 2022-11-09 4 SGEN Seagen Inc.
Common Stock
A - Award 107,389 107,389
2022-06-30 2022-06-30 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,874 93,932 3.16
2022-06-30 2022-06-30 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,053 91,058 2.31
2022-06-10 2022-06-08 4 SNTI Dynamics Special Purpose Corp.
Common Stock
A - Award 112,519 123,252 1,048.35
2022-06-03 2022-05-19 4 AXLA Axcella Health Inc.
Common Stock
A - Award 47,059 209,756 28.92
2022-06-01 2022-05-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 89,005 3.34
2022-06-01 2022-05-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,052 86,132 2.44
2022-05-31 2022-05-27 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 17,123 84,080 25.57 1.46 25,000 122,757
2022-05-13 2022-05-12 4 RUBY Rubius Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 499,762 499,762
2022-05-02 2022-05-02 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,873 5,747 -33.33
2022-05-02 2022-05-02 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,053 4,105 -33.34
2022-05-02 2022-05-02 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 66,957 4.48
2022-05-02 2022-05-02 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,053 64,084 3.31
2022-04-22 2022-04-21 4 RUBY Rubius Therapeutics, Inc.
Common Stock
P - Purchase 30,000 4,720,012 0.64 1.44 43,329 6,817,113
2022-04-01 2022-03-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,874 8,620 -25.00
2022-04-01 2022-03-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,052 6,158 -24.99
2022-04-01 2022-03-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,874 62,031 4.86
2022-04-01 2022-03-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,052 59,157 3.59
2022-03-21 2022-03-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 0 -100.00
2022-03-21 2022-03-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 162,697 0.95
2022-03-21 2022-03-17 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 50,000 50,000
2022-03-18 2022-03-16 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 26,178 161,162 19.39 1.91 50,000 307,819
2022-03-01 2022-02-28 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,873 11,494 -20.00
2022-03-01 2022-02-28 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,053 8,210 -20.00
2022-03-01 2022-02-28 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 57,105 5.30
2022-03-01 2022-02-28 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,053 54,232 3.93
2022-02-23 2022-02-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,534 1,535 -49.98
2022-02-23 2022-02-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,534 134,984 1.15
2022-01-31 2022-01-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,873 14,367 -16.66
2022-01-31 2022-01-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,052 10,263 -16.66
2022-01-31 2022-01-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 52,179 5.83
2022-01-31 2022-01-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,052 49,306 4.34
2022-01-20 2022-01-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 3,069 -33.34
2022-01-20 2022-01-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 133,450 1.16
2022-01-03 2021-12-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,874 17,240 -14.29
2022-01-03 2021-12-31 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,052 12,315 -14.28
2022-01-03 2021-12-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,874 47,254 6.48
2022-01-03 2021-12-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,052 44,380 4.85
2021-12-20 2021-12-17 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 4,604 -25.00
2021-12-20 2021-12-17 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 131,915 1.18
2021-12-01 2021-11-30 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,873 20,114 -12.50
2021-12-01 2021-11-30 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,053 14,367 -12.50
2021-12-01 2021-11-30 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 42,328 7.28
2021-12-01 2021-11-30 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,053 39,455 5.49
2021-11-22 2021-11-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,534 6,139 -19.99
2021-11-22 2021-11-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,534 130,380 1.19
2021-11-01 2021-11-01 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,873 22,987 -11.11
2021-11-01 2021-11-01 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,052 16,420 -11.11
2021-11-01 2021-11-01 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,873 37,402 8.32
2021-11-01 2021-11-01 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,052 34,529 6.32
2021-10-26 3 OHAA Opy Acquisition Corp. I
Common Stock
0
2021-10-19 2021-10-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 7,673 -16.67
2021-10-19 2021-10-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 128,846 1.21
2021-10-01 2021-10-01 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,874 25,860 -10.00
2021-10-01 2021-10-01 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -2,053 18,472 -10.00
2021-10-01 2021-10-01 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,874 32,477 9.71
2021-10-01 2021-10-01 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 2,053 29,603 7.45
2021-09-20 2021-09-17 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 9,208 -14.29
2021-09-20 2021-09-17 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 127,311 1.22
2021-09-03 2021-09-03 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -5,746 28,734 -16.66
2021-09-03 2021-09-03 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
M - Exercise -4,104 20,525 -16.66
2021-09-03 2021-09-03 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 5,746 27,550 26.35
2021-09-03 2021-09-03 4 EVLO Evelo Biosciences, Inc.
Common Stock
M - Exercise 4,104 21,804 23.19
2021-08-19 2021-08-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,534 10,743 -12.49
2021-08-19 2021-08-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,534 125,776 1.23
2021-07-20 2021-07-16 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 12,277 -11.11
2021-07-20 2021-07-16 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 124,242 1.25
2021-07-02 2021-06-30 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
A - Award 34,480 34,480
2021-07-02 2021-06-30 4 EVLO Evelo Biosciences, Inc.
Restricted Stock Units
A - Award 24,629 24,629
2021-06-21 2021-06-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 13,812 -10.00
2021-06-21 2021-06-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 122,707 1.27
2021-05-25 3 DYNS Dynamics Special Purpose Corp.
Class A common stock
10,733
2021-05-20 2021-05-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,534 15,347 -9.09
2021-05-20 2021-05-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,534 121,172 1.28
2021-05-13 2021-05-12 4 RUBY Rubius Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 27,919 27,919
2021-04-20 2021-04-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
M - Exercise -1,535 16,881 -8.34
2021-04-20 2021-04-18 4 AXLA Axcella Health Inc.
Common Stock
M - Exercise 1,535 119,638 1.30
2021-03-22 2021-03-18 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 120,000 120,000
2021-03-22 2021-03-18 4 AXLA Axcella Health Inc.
Restricted Stock Units
A - Award 18,416 18,416
2021-02-16 2021-02-11 4 RUBY Rubius Therapeutics, Inc.
Common Stock
S - Sale X -26,704 4,690,012 -0.57 14.93 -398,560 69,998,898
2021-02-10 2021-02-10 4 RUBY Rubius Therapeutics, Inc.
Common Stock
S - Sale X -7,404 4,716,716 -0.16 14.79 -109,525 69,772,965
2021-02-10 2021-02-09 4 RUBY Rubius Therapeutics, Inc.
Common Stock
S - Sale X -2,100 4,724,120 -0.04 14.83 -31,146 70,065,313
2021-02-10 2021-02-08 4 RUBY Rubius Therapeutics, Inc.
Common Stock
S - Sale X -89,233 4,726,220 -1.85 14.88 -1,328,117 70,343,641
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 200 17,700 1.14 7.02 1,404 124,254
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 500 17,500 2.94 6.98 3,490 122,150
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 1,000 17,000 6.25 6.91 6,910 117,470
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 800 16,000 5.26 7.16 5,728 114,560
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 4,970 15,200 48.58 6.49 32,255 98,648
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 30 10,230 0.29 6.45 194 65,984
2020-12-14 2020-12-11 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 200 10,200 2.00 6.40 1,280 65,280
2020-11-04 2020-11-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 1,071 6,397 20.10 105.07 112,500 672,182
2020-10-14 2020-10-11 4 EVLO Evelo Biosciences, Inc.
Stock Option (Right to Buy)
A - Award 44,743 44,743
2020-10-14 2020-10-11 4 EVLO Evelo Biosciences, Inc.
Stock Option (Right to Buy)
A - Award 59,395 59,395
2020-09-01 2020-08-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 1,000 10,000 11.11 4.58 4,580 45,800
2020-09-01 2020-08-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 1,000 9,000 12.50 4.48 4,480 40,320
2020-09-01 2020-08-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 1,000 8,000 14.29 4.47 4,470 35,760
2020-09-01 2020-08-31 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 2,752 7,000 64.78 4.46 12,274 31,220
2020-09-01 2020-08-28 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 3,248 4,248 324.80 4.40 14,291 18,691
2020-09-01 2020-08-28 4 EVLO Evelo Biosciences, Inc.
Common Stock
P - Purchase 1,000 1,000 4.34 4,340 4,340
2020-06-08 2020-06-05 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 6,800 6,800
2020-05-26 2020-05-21 4 RUBY Rubius Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 115,771 115,771
2020-05-22 2020-05-20 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 65,000 65,000
2020-05-22 2020-05-20 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 35,000 35,000
2020-05-20 2020-05-18 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 50,000 118,103 73.42 4.75 237,500 560,989
2020-05-08 2020-05-06 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 1 5,255 0.02 131.31 107 690,096
2020-05-08 2020-05-06 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 1,047 1,047
2020-05-05 2020-05-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 997 5,255 23.42
2020-05-05 2020-05-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
D - Sale to Issuer -997 0 -100.00
2020-03-19 2020-03-17 4 RUBY Rubius Therapeutics, Inc.
Common Stock
P - Purchase 5,000 4,815,453 0.10 3.76 18,800 18,106,103
2020-03-17 2020-03-13 4 RUBY Rubius Therapeutics, Inc.
Common Stock
P - Purchase 5,000 4,810,453 0.10 4.00 20,000 19,241,812
2020-03-17 2020-03-13 4 RUBY Rubius Therapeutics, Inc.
Common Stock
P - Purchase 5,000 4,805,453 0.10 3.82 19,100 18,356,830
2020-03-02 2020-02-28 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 2,005 68,103 3.03 3.75 7,519 255,386
2020-03-02 2020-02-27 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 12,800 66,098 24.02 3.65 46,720 241,258
2019-12-03 2019-11-27 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 1,005 53,298 1.92 3.91 3,930 208,395
2019-12-03 2019-11-26 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 14,000 52,293 36.56 3.55 49,700 185,640
2019-12-02 2019-11-27 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 1,005 53,298 1.92 3.91 3,930 208,395
2019-12-02 2019-11-26 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 14,000 52,293 36.56 3.55 49,700 185,640
2019-11-05 2019-11-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 462 4,203 12.35 121.74 56,250 511,721
2019-09-17 2019-09-14 4 EVLO Evelo Biosciences, Inc.
Stock Option (Right to Buy)
A - Award 75,000 75,000
2019-09-17 2019-09-14 4 EVLO Evelo Biosciences, Inc.
Stock Option (Right to Buy)
A - Award 75,000 75,000
2019-08-23 2019-08-21 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 65,000 65,000
2019-08-23 2019-08-21 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 35,000 35,000
2019-08-05 2019-08-02 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 2,849 38,293 8.04 7.04 20,057 269,583
2019-08-05 2019-08-01 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 4,092 35,444 13.05 6.98 28,562 247,399
2019-07-18 2019-07-17 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 1,000 31,352 3.29 7.55 7,550 236,708
2019-07-10 2019-07-10 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 1,322 30,352 4.55 8.07 10,669 244,941
2019-07-10 2019-07-09 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 4,200 29,030 16.92 8.24 34,608 239,207
2019-07-10 2019-07-08 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 274 24,830 1.12 9.00 2,466 223,470
2019-07-03 2019-07-03 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 56 19,056 0.29 8.99 503 171,313
2019-07-03 2019-07-02 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 3,500 19,000 22.58 8.76 30,678 166,535
2019-07-03 2019-07-01 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 1,000 15,500 6.90 8.74 8,735 135,392
2019-07-01 2019-06-28 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 5,400 20,000 36.99 10.04 54,216 200,800
2019-07-01 2019-06-27 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 100 14,600 0.69 9.15 915 133,590
2019-06-27 2019-06-26 4 AXLA Axcella Health Inc.
Common Stock
P - Purchase 14,500 14,500 9.57 138,765 138,765
2019-06-13 2019-06-12 4 EVLO Evelo Biosciences, Inc.
Stock Option (Right to Buy)
A - Award 15,690 15,690
2019-05-28 2019-05-23 4 RUBY Rubius Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 39,094 39,094
2019-05-24 2019-05-22 4 AXLA Axcella Health Inc.
Stock Option (Right to Buy)
A - Award 11,000 11,000
2019-05-03 2019-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 874 3,699 30.93
2019-05-03 2019-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
D - Sale to Issuer -874 0 -100.00
2019-05-03 2019-05-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 997 997
2019-02-14 2018-11-28 5 RUBY Rubius Therapeutics, Inc.
Common Stock
G - Gift 180,000 180,000
2019-02-14 2018-11-28 5 RUBY Rubius Therapeutics, Inc.
Common Stock
G - Gift -180,000 4,800,453 -3.61
2019-02-14 2018-12-31 5 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 48 2,795 1.75
2018-07-18 2018-07-17 4 RUBY Rubius Therapeutics, Inc.
Stock Option (Right to Buy)
A - Award 1,902,977 1,902,977
2018-07-17 3 RUBY Rubius Therapeutics, Inc.
Common Stock
9,960,906
2018-07-17 3 RUBY Rubius Therapeutics, Inc.
Common Stock
9,960,906
2018-07-17 3 RUBY Rubius Therapeutics, Inc.
Common Stock
9,960,906
2018-05-03 2018-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 874 874
2018-05-03 2018-05-03 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 882 2,747 47.29
2018-05-03 2018-05-03 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
D - Sale to Issuer -882 0 -100.00
2018-02-02 2017-12-31 5 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 25 1,865 1.36
2017-05-05 2017-05-03 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 882 882
2017-05-03 2017-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 938 1,840 103.99
2017-05-03 2017-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
D - Sale to Issuer -938 0 -100.00
2017-02-07 2016-12-31 5 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 3 583 0.52
2017-02-03 2017-02-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 319 899 55.00
2017-02-03 2017-02-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
D - Sale to Issuer -319 0 -100.00
2016-12-06 2016-02-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 160 160 118.46 18,954 18,954
2016-11-03 2016-11-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Stock Equivalent Unit
A - Award 420 420 133.84 56,213 56,213
2016-05-03 2016-05-02 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 938 938
2016-02-02 2016-02-01 4 IFF INTERNATIONAL FLAVORS & FRAGRANCES INC
Restricted Stock Units
A - Award 319 319
P
Open market or private purchase of non-derivative or derivative security
S
Open market or private sale of non-derivative or derivative security
A
Grant, award, or other acquisition of securities from the company (such as an option)
C
Conversion of derivative
D
Sale or transfer of securities back to the company
F
Payment of exercise price or tax liability using portion of securities received from the company
G
Gift of securities by or to the insider
K
Equity swaps and similar hedging transactions
M
Exercise or conversion of derivative security received from the company (such as an option)
V
A transaction voluntarily reported on Form 4
J
Other (accompanied by a footnote describing the transaction)